• Korean Journal of Social Welfare Studies
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• no.39
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• pp.167-187
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• 2008

This study explores the trends of social security expenditures after financial crisis in welfare states. For the purpose, this study analyzes changes in social expenditures during 1980~2003 in 22 OECD countries. The results show that average total social security expenditure(as a percentage of GDP) among the 22 countries increased from 18.0% in 1980 to 22.3% in 2003. Compared to sharp increases during the great expansion period of the welfare state before 1980s, the increase in social expenditures after 1980s is substantially weakened. The slowdown in the increases of social expenditures is remarkable in the social democratic welfare states where social expenditures have already reached a high level. On the other hand, social expenditures are considerably increased in the lagged welfare states such as South European countries and Japan. As a result, the cross-national difference in social expenditures has continuously decreased. These findings suggest that financial crisis is a key factor of welfare-state reorganization. Countries where social expenditures are in high level need more reforms under the pressure of financial deficits. Since 1980s, they have tried various reforms especially in pensions and unemployment benefits. Facing new and increasing demands for social security as well as financial limitations, the welfare state needs major reforms in the social security system to increase effectiveness/efficiency of existing programs and to iron out priorities among programs.

• Economic and Environmental Geology
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• v.52 no.5
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• pp.409-425
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• 2019

Marine terraces, a step-like landform, are important geologic markers that provide tectonic information during the Quaternary Period. Marine terraces are well developed along all coastlines(East, West, and South) of the Korean Peninsula, those along the East coastline are the most distinctive. The marine terraces of the East coastline are classified into 4-6 flights that are several meters or several tens of meters above the present sea level. It is believed that these terraces, except for the lowest one, were formed in the middle Pleistocene. In the base of the OSL age dating results and Blake excursion events of magnetostratigraphy, the $2^{nd}$ and $3^{rd}$ terraces are correlated to the last interglacial stage. Considering the marine terraces linked to a sea-level curve of the Pleistocene, it is thought that regional tectonic movements have uplifted the East coastal area since the middle Pleistocene. Besides, former shorelines of each terrace have varied elevations from Gangreung to Busan bay, which can be divided into four regions, namely, Gangreung-Yonghanri(I), Homikot-Najung(II), Najung-Bangeojin(III), and Waesung-Busan Bay(IV). The former shorelines of each terrace at both Gangreung-Yonghanri(I) and Najung-Bangeojin(III) are higher than those in the other two regions, due to block movements by regional faults such as the Ocheon Fault or its subsidiaries, the Gampo Lineament and Ulsan Fault. Uplift rate of the East coast ranges from 0.2 m/ky to 0.3 m/ky, but each region shows different uplift rate.

• Journal of Plant Biotechnology
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• v.48 no.3
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• pp.124-130
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• 2021

Nitrate is an important nutrient and signaling molecule in plants that modulates the expression of many genes and regulates plant growth. In this study, we cover the research status of transcription factors related to the control of gene expression by nitrate signaling in higher plants. Nitrate reductase is a key enzyme in nitrogen assimilation, as it catalyzes the nitrate-to-nitrite reduction process in plants. A variety of factors, including nitrate, light, metabolites, phytohormones, low temperature, and drought, modulate the expression levels of nitrate reductase genes and nitrate reductase activity, which is consistent with the physiological role if. Recently, several transcription factors controlling the expression of nitrate reductase genes have been identified in higher plants. NODULE-INCEPTION-Like Proteins (NLPs) are transcription factors responsible for the nitrate-inducible expression of nitrate reductase genes. Since NLPs also control the nitrate-inducible expression of genes encoding the nitrate transporter, nitrite transporter, and nitrite reductase, the expression levels of nitrate reduction pathway-associated genes are coordinately modulated by NLPs in response to nitrate. Understanding the function of nitrate in plants will be useful to create crops with low nitrogen use.

• Journal of Life Science
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• v.29 no.4
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• pp.447-454
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• 2019

Fat accumulation in adipocytes occurs through the process of adipogenesis in which preadipocytes differentiate into adipocytes. Obesity is a metabolic disorder caused by excessive accumulation of fat in the body, which increases the incidence of cardiovascular diseases, hypertension, type 2 diabetes, hyperlipidemia, and various cancers. Recently, inhibition of adipocyte differentiation was shown to be a potential antiobesity strategy. In this study, the inhibitory effect of dichloromethane fractions from Illicium verum Hooker fil. water extract on the differentiation of 3T3-L1 preadipocytes to adipocytes was investigated. Dichloromethane fractions from I. verum Hooker fil. significantly inhibited adipocyte differentiation when applied during the adipocyte differentiation process, as assessed by measuring fat accumulation using Oil-red O staining. In addition, dichloromethane fractions from I. verum Hooker fil. reduced important adipogenic transcription factors, such as CCAAT/enhancer binding protein ${\alpha}$ ($C/EBP{\alpha}$), $C/EBP{\beta}$, and peroxisome proliferator activated receptor ${\gamma}$ ($PPAR{\gamma}$). The expression of FAS and LPL, which are terminal differentiation markers of mature adipocytes, was also reduced in the 3T3-L1 adipocytes treated with dichloromethane fractions from I. verum Hooker fil. In addition, the treatment significantly inhibited mitotic clonal expansion, which is essential for adipocyte differentiation, by arresting the G1 phase of the cell cycle. Taken together, these results suggest that dichloromethane fractions from I. verum Hooker fil. may be a natural material with antiobesity effects.

• The Korean Journal of Archival Studies
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• no.30
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• pp.175-204
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• 2011

Electronic records are generated not only in public sector but also in private sector. Records will be used across the public-private boundary. The Certified e-Document Authorities(CeDAs) may keep electronic documents in private sector for preservation and evidence, like the official Record Management Systems for Public sector. A CeDA is the Trusted Third Party (TTP) as a business to be entrusted and proof interchanging documents between parties. This CeDA system could be sustainable only if the CeDA earn the enough sales through enough uses. And yet, all the eight CeDA companies have not had enough users. How to utilize CeDAs is one of the hot issues in this area. In this paper, We analyze the threat to trustworthiness of CeDA due to payment of only one party among others, and describe the difficulty in use of CeDA for an individual user. These things make CeDAs cannot have enough users. To do address these, We expand the boundary of relevant parties for a document, present a delegate-establishing option under a joint name, show the needs of identifying and notifying minimum relevant parties, and suggest the proxy parties to help the individual users.

• Food Science and Industry
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• v.53 no.4
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• pp.390-396
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• 2020

We investigated the anti-obesity effect of Gelidium elegans extract (GE) on 3T3-L1 preadipocytes and a high-fat-diet (HFD)-induced mouse model. The results of the present study demonstrated that GE prevents weight gain induced by a high-fat diet (HFD) by modulating the adenosine monophosphate-activated protein kinase (AMPK)-PR domain-containing 16 (PRDM16)-uncoupling protein-1 (UCP-1) pathway in a mice model. Moreover, in vitro results show that GE suppressed adipocyte differentiation by modulating adipogenic regulators, stimulated lipolysis by activating ATGL, and inhibited adipogenesis by downregulating various enzymes associated with triglyceride synthesis. GE was also found to upregulate AMPK phosphorylation as well as the expression of UCP1 and PRDM16 proteins, leading to measurable changes in the beige-like phenotype differentiation of 3T3-L1 cells. Taken together, these findings suggest the role of GE as a functional food ingredient extracted from Gelidium elegans to increase energy expenditure and anti-obesity efficacy.

• Science of Emotion and Sensibility
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• v.24 no.2
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• pp.25-38
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• 2021

The aim of this study is to protect workers and pedestrians from accidents at night or bad weather by attaching optical fiber to existing safety clothing that is made only with fluorescent fabrics and retroreflective materials. A safety vest was designed and manufactured by applying optical fiber, and energy-harvesting technology was developed. The safety vest was designed to emit light using the automatic flashing of optical fibers attached to the film, and an energy harvester was manufactured and attached to drive the light emission of the optical fiber more continuously. As a result, first, the vest wearer' body was recognized from a distance through the optical fiber and retroreflection, which helped prevent accidents. Thus, this concept helps in saving lives by preventing accidents during night-time work on the roadside or activities of rescue crew and sports activities, or by quickly finding the point of an accident with a signal that changes the optical fiber light emission. Second, to use the wasted energy, a piezoelectric-element power generation system was developed and the piezoelectric-harvesting device was mounted. Potentially, energy was efficiently produced by activating the effective charging amount of the battery part and charging it auxiliary. In the existing safety vest, detecting the person wearing the vest is almost impossible in the absence of ambient light. However, in this study, the wearer could be found within 100 m by the light emission from the safety vest even with no ambient light. Therefore, in this study, we will help in preventing and reducing accidents by developing smart safety clothing using optical fiber and energy harvester attached to save lives.

• Journal of Life Science
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• v.33 no.5
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• pp.436-444
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• 2023

Scientific training, diet, and ergogenic aids are widely used to overcome the limits of humans' physical abilities and to achieve excellent sports records. The adoption of nutritional strategies is important for athletes to perform at their highest level, and one of the main factors determining endurance ability is increased fat metabolism. A ketogenic diet (high fat, low carbohydrates) has thus been proposed as an alternative strategy to maximize fatty acid oxidation during prolonged periods of exercise. However, studies have shown mixed results regarding the ergogenic value of a ketogenic diet. For this reason, exogenous ketone supplements (EKS, ingestible forms of ketone bodies, ketone esters, and/or salts) have been suggested to obtain nutritional ketosis, an acute transient increase in circulating acetoacetate (AcAc) and b-hydroxybutyrate (bHB) concentrations, without limiting carbohydrate intake. Some studies have suggested the beneficial effects of EKS on the performance of endurance exercises by providing an additional fuel substrate for peripheral tissues, such as cardiac and skeletal muscles, sparing carbohydrates/increasing fat oxidation and post-exercise recovery by increasing glycogen resynthesis in the liver/muscle, attenuating protein degradation, stimulating protein synthesis in the skeletal muscle, etc. However, many studies have failed to observe the beneficial effects of EKS as an ergogenic aid. As such, this review summarizes the theoretical basis of, as well as the proposed and proven effects of EKS on exercise performance and recovery to date.

• Journal of Nutrition and Health
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• v.57 no.3
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• pp.307-319
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• 2024

Purpose: This study compared the differences in health and dietary characteristics between middle-aged men and women according to their health-related quality of life. Methods: This study used the data from the 2019 and 2021 Korea National Health and Nutrition Examination Survey (KNHANES). The participants were men (n = 1,571) and women (n = 2,179) aged 40-59. A health-related Quality of Life Instrument with eight items (HINT-8) was used to measure the health-related quality of life. The participants were divided into four groups based on their HINT-8 total scores (high, mid-high, mid-low, and low). The general and health characteristics, mental health, and dietary behaviors were compared according to the quality of life. Results: Men with a lower quality of life had lower incomes, were more likely to be single, smoked and drank more, and perceived themselves as slim or obese. Women with a lower quality of life had a higher proportion of older age, obesity, lower education and income, hypercholesterolemia, and hypertriglyceridemia. Both men and women with a lower quality of life had higher proportions of subjectively perceiving poor health, weight gain over the past year, and considering themselves as obese. Both men and women with a lower quality of life had lower consumption frequencies of vegetables/mushrooms/seaweed and fruits. Conclusion: Both men and women with lower health-related quality of life had lower incomes, higher rates of perceiving their health as poor, and consumed vegetables/ mushrooms/seaweed and fruits less frequently, but they showed different characteristics in other aspects. Therefore, policy development tailored to men and women is necessary.

• Journal of Applied Biological Chemistry
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• v.66
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• pp.369-378
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• 2023

Smilax sieboldii is one of the Smilax species. A number of Smilax plants have multiple physiologically-active components and anti-inflammatory/anti-oxidant effects. Antiobesity effects induced by Smilax sieboldii have not been reported. In this study, we investigated the effects and molecular mechanisms of anti-obesity activity of 70% ethanol Smilax sieboldii extract (SSE). The anti-obesity effect of SSE was determined using 3T3-L1 adipocytes. We confirmed that SSE was not cytotoxic to murine 3T3-L1 preadipocytes, we evaluated SSE dose-dependently decreased the accumulation of lipids via an Oil Red O assay and triglyceride assay. These anti-obesity activities of SSE were mediated by the inhibition of adipogenesis-related marker genes (peroxisome proliferator activated receptor-γ, CCAAT-enhancer-binding protein α, and SREBP1c) and lipogenesis-related marker genes (fatty acid synthase and aP2). These results suggest that SSE has the potential to exert anti-obesity and anti-hyperlipidemia effects by regulating adipogenic transcription factors and inhibiting the expression of adipogenic markers.