• Title/Summary/Keyword: 한국바이오텍

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Hepatoprotective effect of fermented Chrysanthemum indicum L. water extract on ethanol-induced liver injury in HepG2 cells (감국 발효 열수 추출물의 에탄올에 의해 손상된 HepG2 세포의 간보호 효과)

  • Seo, Tae-Su;Han, Joon-Hee;Hong, Min;Choi, Da-Hye;Lee, Deug-Chan;Yu, Keun-Hyung
    • Korean Journal of Food Science and Technology
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    • v.53 no.3
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    • pp.260-266
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    • 2021
  • This study aimed to identify the hepatoprotective effects of a fermented Chrysanthemum indicum L. water extract. The extraction yield, antioxidant activities (ABTS and DPPH), and content of luteolin and luteolin-7-glucoside were significantly higher in the fermented C. indicum L. water extract (FCI) than in the C. indicum L. water extract. Treatment with FCI (200 ㎍/mL) significantly reduced the activities of gamma(γ)-glutamyl transferase, aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase in HepG2 cells treated with 3% ethanol. Furthermore, FCI did not affect the viability of the HepG2 cells. These results suggest that FCI can be useful for the development of an effective hepatoprotective agent.

Evaluating Joint Motion Sensing Efficiency According to the Implementation Method of CNT-Based Fabric Sensors (CNT 기반의 직물센서 구현 방법에 따른 관절동작 센싱 효율 평가)

  • Cho, Hyun-Seung;Yang, Jin-Hee;Lee, Joo-Hyeon
    • Science of Emotion and Sensibility
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    • v.24 no.4
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    • pp.129-138
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    • 2021
  • This study aimed to determine the effects of the shape and attachment position of stretchable textile sensors coated with carbon nanotube on their performance when used to measure children's joint movements. Moreover, the child-safe requirements for fabric motion sensors are established. The child participants were advised to wear integrated clothing equipped with the sensors of various shapes (rectangular and boat-shaped) and attachment positions (at the knee and elbow joints or 4 cm below the joints). The voltage change induced by the elongation and contraction of the fabric sensors was determined for arm and leg flexion-extension motions at 60 deg/s (three measurements of 10 repeats each for 60°and 90°angles, for a total of 60 repetitions). Their dependability was determined by comparing the fabric motion sensors to the associated acceleration sensors. The experimental results indicate that the rectangular-shaped sensor affixed 4 cm below the joint is the most effective fabric motion sensor for measuring children's arm and leg motions. In this study, we designed a textile sensor capable of tracking children's joint motion and analyzed the sensor shape and attachment position on motion sensing clothing. We demonstrated that flexible fabric sensors integrated into garments may be used to detect the joint motions of the human body.

Resistance screening of white mustard(Sinapis alba) plant resources against clover cyst nematode, Heterodera trifolii (클로버씨스트선충에 대한 백겨자 식물자원의 저항성 스크리닝)

  • Hyoung-Rai Ko;Jinwon Kim;Sekeun Park;Natesan Karthi;Byeong-Yong Park;Seon Hwa Kim;Jin-Cheol Kim
    • Korean Journal of Environmental Biology
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    • v.42 no.1
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    • pp.135-142
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    • 2024
  • Clover cyst nematode (Heterodera trifolii, CCN) is one of the important plantparasitic nematodes in the Republic of Korea, causing serious damage to Kimchi-cabbage in Gangwon province since 2017. Soil fumigants are the preferred choice for managing CCN. However, cabbage fields in Gangwon province have a slope, making it challenging to apply soil fumigants and use plastic mulch. Consequently, alternative materials should be developed for managing CCN. Nematicidal cover crops and resistant cultivars are among the alternatives. We conducted resistance screening of 82 white mustard(Sinapis alba) resources from a genebank at RDA against CCN for use as nematicidal cover crops or breeding materials. In the first assay (1st, 2nd, and 3rd pot experiments), 15 white mustard resources were selected, while others were susceptible to CCN. To confirm the reproducibility of resistance to CCN for 13 selected resources, the second assay was performed. As a result, five white mustard resource (IT297309, IT297312, IT302951, IT302953, IT302954) demonstrated resistance to CCN. These findings indicate the potential use of these five white mustard resources as nematicidal cover crops or for breeding cultivars of Kimchi-cabbage in Republic of Korea.

Growth of Intestinal Bacteria and Intestinal Inflammation of Sprout Extract from Common Buckwheat and Tartary Buckwheat (일반메밀과 쓴메밀의 새싹 추출물의 장내 유익균 증식 및 염증조절 효능 평가)

  • Su Jeong Kim;Hwang Bae Sohn;Jong Won Kim;Sanghyun Lim;Jong Nam Lee;Su Hyoung Park;Jung Hwan Nam;Do Yeon Kim;Ye Jin Lee;Dong Chil Chang;Yul Ho Kim
    • Korean Journal of Plant Resources
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    • v.36 no.5
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    • pp.455-468
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    • 2023
  • We aimed to assess the potential growth-promoting effects of buckwheat sprout on intestinal bacteria and their anti-inflammation effects in a cellular model of intestinal inflammation. The growth of Bifidobacterium longum ssp. infantis BT1 was enhanced with the addition of the sprout extract of tartary buckwheat. Further, in the inflammatory model cells cultured with Raw 264.7 cells were treated with buckwheat sprout including each 10 probiotics before the addition of lipopolysaccharide (LPS) to induce inflammation in Raw 264.7 cells. Buckwheat sprout in both Bifidobacterium longum ssp. infantis BT1 and Lacticaseibacillus paracasei LPC5 significantly reduced the production of NO and PGE2. The above results indicate that buckwheat sprout extract which contains with various physiologically active substances such as rutin, quercetin, and choline is effective in suppressing NO and PGE2 production, which are inflammation-related indicators. The present study suggests that buckwheat sprout could induce positive effects on the intestinal beneficial bacteria and in anti-inflammation.

A Study on Wearable Emotion Monitoring System Under Natural Conditions Applying Noncontact Type Inductive Sensor (자연 상태에서의 인간감성 평가를 위한 비접촉식 인덕티브 센싱 기반의 착용형 센서 연구)

  • Hyun-Seung Cho;Jin-Hee Yang;Sang-Yeob Lee;Jeong-Whan Lee;Joo-Hyeon Lee;Hoon Kim
    • Science of Emotion and Sensibility
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    • v.26 no.3
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    • pp.149-160
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    • 2023
  • This study develops a time-varying system-based noncontact fabric sensor that can measure cerebral blood-flow signals to explore the possibility of brain blood-signal detection and emotional evaluation. The textile sensor was implemented as a coil-type sensor by combining 30 silver threads of 40 deniers and then embroidering it with the computer machine. For the cerebral blood-flow measurement experiment, subjects were asked to attach a coil-type sensor to the carotid artery area, wear an electrocardiogram (ECG) electrode and a respiration (RSP) measurement belt. In addition, Doppler ultrasonography was performed using an ultrasonic diagnostic device to measure the speed of blood flow. The subject was asked to wear Meta Quest 2, measure the blood-flow change signal when viewing the manipulated image visual stimulus, and fill out an emotional-evaluation questionnaire. The measurement results show that the textile-sensor-measured signal also changes with a change in the blood-flow rate signal measured using the Doppler ultrasonography. These findings verify that the cerebral blood-flow signal can be measured using a coil-type textile sensor. In addition, the HRV extracted from ECG and PLL signals (textile sensor signals) are calculated and compared for emotional evaluation. The comparison results show that for the change in the ratio because of the activation of the sympathetic and parasympathetic nervous systems due to visual stimulation, the values calculated using the textile sensor and ECG signals tend to be similar. In conclusion, a the proposed time-varying system-based coil-type textile sensor can be used to study changes in the cerebral blood flow and monitor emotions.

원자력 NEWS

  • Korea Atomic Industry Forum
    • Nuclear industry
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    • v.26 no.4 s.278
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    • pp.85-103
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    • 2006
  • 국제원자력규제자협의회(INRA) 정식 가입/ "원자력 기술 주도국으로 부상"/ "방패장 건설 사업 착실히 추진"/ 방폐장 처분 방식 "객관적이고 투명하게"/ 인도네시아 국회의장 고리 원전 방문/ 세계 원자력 안전 전문가들 한 자리에/ 아시아 태평양 지역 17개국 원자력 협력 토의/ 국제핵융합실험로(ITER) 공동이행협정문서 최종 확정/ 한 · IAEA, 원자력방호기술 향상 방안 협의/ 울진 원전 6호기 리스크 정보 활용 정기 검사 수행/ IAEA, 국내 원전 안전 점검 협의 위해 방한/ 중국 원전 기술단 방한/ 울진 원전 총발전량 4천억kWh 돌파/ 원전 안전 관리 실태 불시 점검 결과 양호/ '핵융합연구센터' 공식 출범/ 핵융합에너지개발진흥법 제정을 위한 공청회 개최/ 제9차 한-미 안전조치 기술협력 회의 개최/ 개량핵연료 'PLUS7' 첫 상용화/ 베트남 원자력 협력 강화 워크숍 개최/ "2015년엔 세계 최우수 발전회사"/ 'APR1400'중국에 적극 홍보/ 한수원, 협력기업에 500억원 지원/ "한국 원자력 도입 경험 배우겠다"/ 방사선원 사고 대비 예방 안전 체계 구축/ "한수원 신용 등급 A+"/ 울진 6호기 '첫번째' 계획 예방 정비착수/ '2006 원자력 체험전' 개최/ 원자로 내부 이물질 감시 시스템 개발/ 월성 3호기 정비 완료, 발전 재개/ IAEA안전조치이행자문단 월성 원전 방문/ 제11회 원자력안전기술정보회의 개최/ 월성 1호기 방사능 방재 전체 훈련 실시/ (주)선바이오텍, 첫 '연구소 기업' 공식 승인/ 방사선원 안전성 향상 워크숍 개최/ 양성자 가속기 사업 본격 궤도에/ 스웨덴 프로스마르크 원전 관계자 방한/ "방폐장 유치한 성숙한 시민 의식 감탄" / "올해는 혁신을 체질화하겠다"/ KAERI, 연구윤리위원회 발족/ 2005년 지식 활동 우수 그룹 포상/

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EEG Signal, Subjective Fragrance Sensation, and Preference of Citrus Oil Microcapsule-Loaded Fabric (감귤 오일 마이크로캡슐 가공 직물에 대한 EEG 신호와 주관적 향기감성 및 선호도)

  • Badmaanyambuu, Sarmandakh;Kim, Chunjeong;Yi, Eunjou
    • Journal of the Korean Society of Clothing and Textiles
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    • v.43 no.2
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    • pp.297-309
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    • 2019
  • This study investigated EEG signal, subjective fragrance sensation, and the preference of differently colored cotton knit treated with Citrus unshiu oil containing microcapsules as well as examined their relationships for providing regression models on subjective fragrance preference. Color variables combining 2-level hue (Yellow and Green) and 3-level tone (strong, pale, and grayish) were applied by dyeing prior to microcapsule treatment. We invited 28 female college students aged 20's for EEG signal experiments and subjective fragrance sensations with fragrant knit by rubbing. EEG signals at $mid-{\alpha}$, $fast-{\alpha}$, and $low-{\beta}$ showed significant differences depending on color; Green had more relative power values and grayish tone did more at $low-{\beta}$. Even though subjective sensation showed no significant differences depending on color, some of them such as Fresh, Comfort, and Natural showed significant correlations with EEG signal at $low-{\beta}$, which means that the fragrance sensations of Citrus unshiu fragrance are concerned with attention and alertness for Koreans. Fragrance preference was regressed significantly using some EEG signals and subjective sensation. The results could be utilized to value up fragrant textiles by Citrus unshiu oil.

A Study on Persona and Self-Presentation through Fashion on Instagram -Focusing on Women in Their 20s and 30s- (인스타그램에서의 페르소나와 패션을 통한 자기표현에 관한 연구 -20~30대 여성을 중심으로-)

  • Won, Yeon Jung;Shin, Eun Jung;Koh, Ae-Ran
    • Journal of the Korean Society of Clothing and Textiles
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    • v.45 no.5
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    • pp.804-824
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    • 2021
  • This study qualitatively explored the case of users utilizing multiple accounts on one social network service to create their own multiple spaces and different personas. The purpose of the study was to understand the behavior of people who use multiple accounts to express their identity online using Carl Jung's personality theory. We used in-depth interviews and the Zaltman metaphor elicitation technique (ZMET), targeting 19 people in their 20s and 30s who use more than one personal account on Instagram. Creating a shared consensus map using the configuration concept of ZMET derived six personas in relation to Instagram accounts. The motivations for the respondents' self-presentation associated with their personas and self-presentation types shown on Instagram were analyzed in terms of persona and fashion and subdivided into five dimensions: relationship management strategic presentation, self-monitoring presentation, competence demonstration presentation, anonymous presentation, and persona-centered presentation. Each respondent's persona and self-presentation formed by the Instagram account was analyzed.

Educational Peptide Mapping of Protein-based Biopharmaceuticals by using LC-MS/MS (LC-MS/MS를 이용한 단백질 의약품 맵핑 교수법)

  • Kim, Junseok
    • Journal of Practical Engineering Education
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    • v.14 no.2
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    • pp.327-332
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    • 2022
  • This experiment presents a precise analysis method using a mass spectrometer in the biopharmaceutical market, where utility is expanding. Among various techniques for analyzing the protein drug, somatotropin, the peptide fragments through biochemical sample preparation was analyzed by LC-MS/MS characterization. The analysis process was performed by separation analysis using nanoUPLC and MS/MS analysis using Orbitrap. In the case of somatotropin with 21 tryptic peptides, 13 of them were consistent with theoretical predictions within an average of 1 ppm error.

Anti-oxidant and Anti-inflammatory Activities of Beet (Beta vulgaris) Sprout Extract (비티 새싹 추출물의 항산화 및 항염효과)

  • Song-I Han;Ji Hun Byeon;Mi Sook Kang;So-Mi Kang;Jae-Hoon Kim
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.12a
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    • pp.77-77
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    • 2020
  • 본 연구에서는 비트 새싹 추출물의 항산화 및 항염증 효능을 평가하기 위해 3가지 품종의 레드 비트(메를린, 우단, 디트로이트다크레드) 새싹을 60% 에탄올로 추출한 후 free radical 소거활성, 총 폴리페놀 함량을 측정하였다. 또한, LPS로 염증반응이 유도된 대식세포인 RAW264.7 세포에서 nitric oxide(NO) 생성억제 효과를 알아보았다. 메를린, 우단, 디트로이트다크레드 새싹 추출물의 총 폴리페놀 함량을 querceitn을 표준물질로 사용하여 측정한 결과 2.84 mg Que/g, 2.61 mg Que/g, 2.71 mg Que/g으로 나타났고 DPPH 라디칼 소거능은 농도 의존적으로 증가하였으며, 200 ㎍/ml일 때, 55%, 72%, 63%로 나타났다. 또한, DPPH 라디칼 소거능이 가장 높은 메를린 새싹 추출물은 LPS로 염증반응이 유도된 RAW264.7 세포에서 농도 의존적으로 iNOS와 COX-2를 억제하는 것을 확인하였다. 이러한 결과를 바탕으로 메를린 비트 새싹 추출물이 항산화 및 항염증제의 천연물 소재로 활용이 가능할 것으로 생각된다.

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