• Title/Summary/Keyword: 표면적응

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The effects of properties and interactions of surface molecules in antigen presenting cells on T cell activation (인공 항원제시세포의 표면 분자의 특성 및 상호작용이 T 세포 활성화에 미치는 영향)

  • Min, Youngsil;Kang, Yoon Joong
    • Journal of Convergence for Information Technology
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    • v.10 no.6
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    • pp.164-176
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    • 2020
  • Efficient production of antigen specific cytotoxic T cells is critical for appropriate adoptive immune response. In vitro culture and expansion of human T lymphocyte clones are very sophisticated and subtle procedure in immune cell therapy and hard to control. Therefore, many groups devoted their efforts to manipulate artificial antigen presenting cells (aAPCs) that can induce T cell activation and clonal expansion. To mimicking of natural antigen-presenting cells, aAPCs encompass basic signal molecules required for T cell activation: MHC:antigen complexes, co-stimulatory molecules and soluble immune modulating molecules. Orchestrated organization of these molecules is important for efficient T cell activation. Here, we discuss how those molecules have been incorporated in several aAPC models, but also how physical properties od aAPC are important for interaction with T cells.

Fast Algorithm for the Capacitance Extraction of Large Three Dimensional Object (대용량 3차원 구조의 정전용량 계산을 위한 Fast Algorithm)

  • Kim, Han;Ahn, Chang-Hoi
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.14 no.1
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    • pp.27-32
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    • 2003
  • This paper describes to extend the fast algorithm fur the capacitance extraction of large three-dimensional object. The triangular meshes are used and refined adaptively in the area where the heavy charges reside in each iterative solving. This technique is applied to the capacitance extraction of a 68-pin cerquad package. The results show fast convergence, and this adaptive technique coupled with the fast algorithm is efficient to reduce the number of elements and computing time with least additional computational efforts in large three dimensional problems.

Aberration Extraction Algorithm for LCD Defect Detection (대면적 LCD 결함검출을 위한 수차량 추출 알고리즘)

  • Ko, Jung-Hwan;Lee, Jung-Suk;Won, Young-Jin
    • 전자공학회논문지 IE
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    • v.48 no.4
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    • pp.1-6
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    • 2011
  • In this paper we show the LCD simulator for defect inspection using image processing algorithm and neural network. The defect inspection algorithm of the LCD consists of preprocessing, feature extraction and defect classification. Preprocess removes noise from LCD image, using morphology operator and neural network is used for the defect classification. Sample images with scratch, pinhole, and spot from real LCD color filter image are used. From some experiments results, the proposed algorithms show that defect detected and classified in the ratio of 92.3% and 94.5 respectively. Accordingly, in this paper, a possibility of practical implementation of the LCD defect inspection system is finally suggested.

Three Dimensional Finite Element Analysis of Filling Stage in Casting Process Using Adaptive Grid Refinement Technique (3차원 적응 격자 세분화를 이용한 주조 공정의 충전 해석)

  • Kim Ki Don;Jeong Jun Ho;Yang Dong Yol
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.29 no.5 s.236
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    • pp.568-576
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    • 2005
  • A 3-D finite element model combined with a volume tracking method is presented in this work to simulate the mold filling for casting processes. Especially, the analysis involves an adaptive grid method that is created under a criterion of element categorization of filling states and locations in the total region at each time step. By using an adaptive grid wherein the elements, finer than those in internal and external regions, are distributed at the surface region through refinement and coarsening procedures, a more efficient analysis of transient fluid flow with free surface is achieved. Adaptive grid based on VOF method is developed in tetrahedral element system. Through a 3-D analysis of the benchmark test of the casting process, the efficiency of the proposed adaptive grid method is verified. Developed FE code is applied to a typical industrial part of the casting process such as aluminum road wheel.

Document Image Binarization Using a Water Flow Model (Water Flow Model을 이용한 문서 영상의 이진화)

  • Kim, In-Gwon;Jeong, Dong-Uk;Song, Jeong-Hui;Park, Rae-Hong
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.38 no.1
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    • pp.19-32
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    • 2001
  • This paper proposes a local adaptive thresholding method based on a water flow model, in which an image surface is considered as a 3-dimensional (3-D) terrain. To extract characters from backgrounds, we pour water onto the terrain surface. Water flows down to the lower regions of the terrain and fills valleys. Then, the amount of filled water is thresholded, in which the proposed thresholding method is applied to gray level document images consisting of characters and backgrounds. The proposed method based on a water flow model shows the property of locally adaptive thresholding. Computer simulation with synthetic and real document images shows that the proposed method yields effective adaptive thresholding results for binarization of document images.

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LCD Defect Detection using Neural-network based on BEP (BEP기반의 신경회로망을 이용한 LCD 패널 결함 검출)

  • Ko, Jung-Hwan
    • 전자공학회논문지 IE
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    • v.48 no.2
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    • pp.26-31
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    • 2011
  • In this paper we show the LCD simulator for defect inspection using image processing algorithm and neural network. The defect inspection algorithm of the LCD consists of preprocessing, feature extraction and defect classification. Preprocess removes noise from LCD image, using morphology operator and neural network is used for the defect classification. Sample images with scratch, pinhole, and spot from real LCD color filter image are used. From some experiments results, the proposed algorithms show that defect detected and classified in the ratio of 92.3% and 94.5 respectively. Accordingly, in this paper, a possibility of practical implementation of the LCD defect inspection system is finally suggested.

A Study on Compliance Robot Using a PID Adaptive Controller (PID 적응 제어기를 이용한 컴플라이언스 로보트에 대한 연구)

  • Kim, Seung-Woo;Kang, Moon-Sik;Koh, Jae-Won;Park, Mign-Yong;Lee, Sang-Bae
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.27 no.2
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    • pp.105-110
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    • 1990
  • In this paper, a compliance robot control algorithm using a PID adaptive controller is proposed. The compliance robot is suitable for the tasks in contact with environment, such as assembly operation or surface processing. A hybrid robot control method can control force and position simultaneously and two independant feedback closed loops are formed in this method. Because the compliance robot is operated in contact with environment, it is very difficult to obtain linear model of dynamics for this robot. In order to overcome this difficulty, a PID adaptive controller independant of robot dynamics is applied to the compliance robot. The proposed control algorithm for the compliance robot was analyzed and conformed by simulating the surface processing task by a two-joint robot.

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Development of a Laser-Generated Ultrasonic Inspection System by Using Adaptive Error Correction and Dynamic Stabilizer (적응적 에러 보정과 다이나믹 안정기를 이용한 레이저 유도 초음파 검사 시스템 개발)

  • Park, Seung-Kyu;Baik, Sung-Hoon;Park, Moon-Cheol;Lim, Chang-Hwan;Ra, Sung-Woong
    • Journal of the Korean Society for Nondestructive Testing
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    • v.25 no.5
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    • pp.391-399
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    • 2005
  • Laser-generated ultrasonic inspection system is a non-contact scanning inspection device with high spatial resolution and wide bandwidth. The amplitude of laser-generated ultrasound is varied according to the energy of pulse laser and the surface conditions of an object where the CW measuring laser beam is pointing. In this paper, we correct the generating errors by measuring the energy of pulse laser beam and correct the measuring errors by extracting the gain information of laser interferometer at each time. h dynamic stabilizer is developed to stably scan on the surface of an object for an laser-generated ultrasonic inspection system. The developed system generates ultrasound after adaptively finding the maximum gain time of an laser interferometer and processes the signal in real time after digitization with high speed. In this paper, we describe hardware configuration and control algorithm to build a stable laser-generated ultrasonic inspection system. Also, we confirmed through experiments that the proposed correction method for the generating errors and measuring errors is effective to improve the performance of a system.

The effects of non-condensable gas on condensation heat transfer on a super-hydrophobic surface tube (초소수성 코팅 튜브에서의 비응축가스 영향에 대한 응축 열전달 연구)

  • Ji, Dae-Yun;Kim, Daeho;Lee, Kwon-Yeong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.4
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    • pp.517-524
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    • 2018
  • This purpose of this research is to observe the influence of non-condensable gas (NCG) on a horizontal super-hydrophobic aluminum tube and compare it with a bare aluminum tube. To achieve super-hydrophobic characteristics, an aluminum tube was coated with a Self-Assembled Monolayer (SAM). The overall heat transfer coefficient U was used to represent the condensation performance. The NCG mass fraction was the main variable, and its range was 0.08 to 0.45. The condensation performance of the SAM tube and bare tube increased with decreasing mass fraction of NCG. The SAM tube showed 1.9 to 2.5 times larger dropwise condensation performance than the bare tube. When the mass fraction of NCG decreased in the SAM tube, the rate of increase of the SAM tube was lower because flooded condensation occurred. In addition, filmwise condensation occurred in the SAM tube when more active condensation was generated, and its performance was lower than that of the bare aluminum tube. The flooded and filmwise condensation in the SAM tube is explained by the pinning effect. In conclusion, controlling the condition of the condenser is necessary to improve the condensation performance by surface modification a SAM.

Adsorption of Heavy Metal Ions from Aqueous Solution by Chestnut Shell (밤 부산물의 수용액 중 중금속 흡착 특성)

  • Lee, Hyeon-Yong;Hong, Ki-Chan;Lim, Jung-Eun;Joo, Jin-Ho;Yang, Jae-E;Ok, Yong-Sik
    • Korean Journal of Environmental Agriculture
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    • v.28 no.1
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    • pp.69-74
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    • 2009
  • In Korea, large amounts of chestnut shell as by-products are produced from food industries. However, most of the by-products exist with no disposal options. Biosorption uses biomass that are either abundant or wastes from industrial operations to remove toxic metals from water. Objective of this research was to evaluate the feasibility of using chestnut shell as by-products for removal of metal ions(Pb, Cu and Cd) from aqueous solution. The chestnut shell was tested for its efficiency for metal removal by adopting batch-type adsorption experiments. The adsorption selectivity of chestnut shell for metals was Pb > Cu > Cd at solution pH 5.5. The Langmuir isotherm adequately described the adsorption of chestnut shell for each metal. Using The maximum adsorption capacity predicted using Langmuir equation was 31.25 mg $g^{-1}$ 7.87 mg $g^{-1}$ and 6.85 mg $g^{-1}$ for Pb, Cu and Cd, respectively. Surface morphology, functional group and existence of metals on chestnut shell surface was confirmed by FT-IR, SEM and EDX analysis. The chestnut shell showed an outstanding removal capability for Pb compared to various adsorbents reported in the literatures. The overall results suggested that chestnut shell might can be used for biosorption of Pb from industrial wastewater.