• Title/Summary/Keyword: 평균 h-지수

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Evaluation of the usefulness of Halcyon VMAT treatment plan through comparison with tomotherapy in bilateral breast cancer radiation therapy. (양측 유방암 방사선치료 시 토모테라피와의 비교를 통한 Halcyon VMAT 치료계획의 유용성 평가)

  • LIM JUN TAEK;PARK JU YOUNG;PARK SU YEON;JEON SEONG JIN;PARK TAE YANG;HWANG DA JIN
    • The Journal of Korean Society for Radiation Therapy
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    • v.34
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    • pp.83-92
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    • 2022
  • Purpose: To evaluate usefulness of Tomotherapy and Halcyon VMAT treatment in radiation therapy for bi-breast cancer Materials and Methods: For 10 patients with bi-breast cancer, volumetric modulated arc therapy(VMAT) treatment plan was established using helical Tomotherapy(Accuray. USA) with field width of 5.0-cm and pitch of 0.287, and Halcyon(Varian Medical System, Palo Alto, CA, Version 3.0 USA) of 6arc and 8arc. Prescribed dose was 42.4 Gy/16, and V 40.3Gy of Planning Target Volume(PTV) was 90%. The quality of plan was evaluated by comparing the dose to tumor and normal organs, and the efficiency was evaluated by comparing total MU and beam on time. Results: About three treatment plans(Tomotherapy, Halcyon 6Arc VMAT, Halcyon 8Arc VMAT) , the mean homogeneity index(H.I) of PTV were 1.07, 1.10, 1.11, and the mean conformity index(C.I) of PTV were 1.21, 1.16, 1.17, respectively. The average value of the dose assessment item for a normal organ is V 5Gy(%) of both lung was 36.3, 31.2, 29.7, and V 15Gy(%) were 18.6, 15.5, 14.6, respectively. The mean heart dose(Gy) were 4.17, 2.69, 2.51. Total MU were (7498.6, 2494.2, 2471.5), and beam on time(sec) were 462.5, 195.4, 198.0. Conclusion: Halcyon VMAT showed similar quality of treatment plan compared to helical Tomotherapy, while also protecting normal organs. In addition, the efficiency of radiotherapy increased due to a decrease in Beam On Time and MU.

A Preliminary Study on Depressive Symptoms and Glycemic Controls in Diabetic Patients (당뇨병 환자에서의 우울 및 관련증상에 관한 예비적 연구)

  • Ko, Seung-Hyun;Jeong, Jong-Hyun;Hong, Seung-Chul;Han, Jin-Hee;Lee, Seung-Pil;Ahn, Yoo-Bae;Song, Ki-Ho
    • Korean Journal of Psychosomatic Medicine
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    • v.12 no.2
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    • pp.165-173
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    • 2004
  • Objectives: Diabetes mellitus is a heterogeneous, chronic, progressive disease characterized by hyperglycemia and abnormality in protein, carbohydrate, fat metabolism. Recent studies have reorted two times prevalence of depression in individuals with diabetes compared to individuals without diabetics. This study was designed to investigate glycemic controls, anxiety, alexithymia, stress responses between depressed diabetic patients and non-depressed diabetic patients. Methods The subjects were 60 diabetic patients(mean age : $50.3{\pm}9.7$ years, 31 men and 29 women) who were confirmed to have diabetes depending on the laboratory findings as welt as clinical symptoms at the St. Vincent Hospital Diabetes Clinic, from Mar. 2004 to Sep. 2004. Laboratory test including, blood chemistry. glycated hemoglobin, urinalysis for proteinuria and Korean version of Beck Depression Inventory(BDI), State and Trait Anxiety Inventory(STAI), Toronto Alexithymia Scale(TAS) and Stress Response Inventory(SRI) were used for assessment. Based on BDI scores, all diabetics were divided into 13 depressed-diabetics group(above 20 point) and 47 non-depressed group(below 20 point). We compared demographic data. glycemic controls, STAI, TAS and SRI scores between two groups by independent t-test. Results : 1) Depressed diabetic groups were 13(mean age : $55.4{\pm}7.2$ years, 7 men and 6 women) and non depressed groups were 47(mean age $48.9{\pm}9.8$ years, 24 men and 23 women). In depressed diabetics, compared with non-depressed group, manifested aged(p=0.031), but other demographic data showed no difference between two groups. 2) No significant differences were noted in FBS, PP2h, Hb A1C, total cholesterol, HDL-cholesterol, SGOT/SGPT, BUN levels between depressed and non-depressed groups. But, blood creatine levels of depressed group were significantly increased than non-depressed group(p=0.026). 3) No significant differences were found in the score of STAI, STAI-S, STAI-T, TAS between depressed and non-depressed groups. 4) The SRI scores of depressed groups were significantly higher than non-depressed groups$(59.7{\pm}24.9\;vs.\;31.5{\pm}22.0)(p=0.000)$. Conclusion : The above results suggest that depressed diabetic patients are have more stress responses and higher blood creatine levels. However, there were no differences in laboratory data related to glycemic controls, and anxiety. alexithymia levels between two groups. We suggest that physicians should consider integrated approaches for psychiatric problems in the management of diabetes.

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Characteristics and Genesis of Terrace Soils in Yeongnam Area -II. Physico-Chemical Properties (영남지역(嶺南地域)에 분포(分布)된 단구지토양(段丘地土壤)의 특성(特性)과 생성연구(生成硏究) -제(第) 2 보(報): 물리화학적(物理化學的) 특성(特性))

  • Jung, Y.T.;Kim, I.H.
    • Korean Journal of Soil Science and Fertilizer
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    • v.18 no.3
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    • pp.289-296
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    • 1985
  • To clarify the soil characteristics and genesis of the clayey terrace soils distributed in Yeongcheon (inland region) and Yeongil (coastal region), 9 typifying pedons including a recent local deposits were studied. The physico-chemical properties found were summarized as follows; 1. The contents of available water of the terrace soils were ranged from 12.0 to 20.3%. They were increased with increaseing clay content up to 35%, and then decreased at clay content of 35 to 55%, but were maintained about 12 to 13% when the clay content exceeds 55%. 2. The amount of water stable aggregates in the surface soils were ranged from 55.0 to 81.1%, and were low in cultivated upland where water erosion were accelerated while high in the paddy where the double cropping were practiced. The index of aggregate in cultivated upland were higher in the surface soils but the paddy soils were higher in subsoils. 3. The colloidal reactions checked by the differences between pH in $0.01N-Na_2SO_4$ and $H_2O$ indicate exchangeable acidity to exchangeable neutrality, which means a sort of Red-yellow soil forming process had been prevailed during genesis of the terrace soils. 4. Cation exchange capacity of the clayey terrace soils were averaged about 15.8-20.2me/100g of fine earth and 35.6-52.6me/100g of clay. The rates of base saturation were 32.7 to 57.6% and the rates decreased with increasing the elevations of terraces. 5. The activities of free iron oxides were 0.061 to 0.739 and the values decreased with increasing elevation while the crystallinity index of iron oxides positively correlated with elevations the values ranged from 0.067 to 0.537.

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Water Chemistry Characteristics and Fish Fauna of Sodo Stream Watershed in Taebaeksan Provincial Park (태백산 도립공원 내 소도천 수계의 이·화학적 수질 특성 및 어류상)

  • Han, Jeong-Ho;Paek, Woon Kee
    • Korean Journal of Environment and Ecology
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    • v.30 no.1
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    • pp.71-80
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    • 2016
  • The fauna of freshwater fish and water chemistry characteristics were investigated from June, 2014 to October, 2014 at 10 sites in Taebaeksan Provincial Park. A total of 7 species under three families were collected from the survey sites and among them one endangered species - Koreocobitis naktongensis - was identified. The endemic species of Korea were 2 species: Koreocobitis naktongensis, Iksookimia koreensis. Dominant species was Rhynchocypris oxycephalus(89%) and subdominant species was Orthrias nudus(8.9%). Water quality including conductivity, turbidity, pH and total dissolved solids(TDS) varied largely depending on the sampling locations. Values of ambient conductivity and TDS were greater in the upstream than in the downstream, and seasonal variabilities were also higher in the upstream. The pH decreased towards the downstream, and especially showed a sharp decrease in S5. This phenomenon was evident due to a dilution by the influx in the acid mine drainage(AMD) of S4. Physical habit conditions, based on qualitative habitat evaluation index(QHEI) model, indicated a "Sub-optimal" condition(mean: 157.3; range: 78 ~ 194) in the Sodo stream watersheds.

Cumulative Deposition of $^{137}Cs$ in the Soil of Korea (한국토양에 존재하는 $^{137}Cs$ 방사능 분포)

  • Lee, Myung-Ho;Choi, Yong-Ho;Shin, Hyun-Sang;Kim, Sang-Bog;Lee, Chang-Woo
    • Journal of Radiation Protection and Research
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    • v.23 no.2
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    • pp.97-102
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    • 1998
  • The cumulative deposition of $^{137}Cs$ in the soil of Korea has been studied. Using ${\gamma$-ray spertrometry, the conrentrations of $^{137}Cs$ were determined for the soil samples collected to a depth of 20 cm. The average accumulated depositions of $^{137}Cs$ were estimated roughly to be 2,501 ${\pm}$ $m^{-2}$ in the forest and 1,058 ${\pm}$ 322 Bq $m^{-2}$ in the hill. The inventory value of $^{137}Cs$ in the forest is about two times higher than that in the hill. Except for some cases, the concentrations of $^{137}Cs$ in the undisturbed soils decreased exponentially with increasing the soil depth. The influences of rainfall, organic matter content, clay content and pH on the deposition of $^{137}Cs$ were studied using the field method. Among these factors, the organic matter content played the most important role in the retention and relative mobility of $^{137}Cs$ in the soil. The other factors such as rainfall, clay content and pH showed weak correlation with the deposition of $^{137}Cs$ in the soil.

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Characteristics and breeding of a new cultivar Pleurotus eryngii, Seolsong (큰느타리버섯 신품종 '설송'의 육성 및 그 특성)

  • Shin, Pyung-Gyun;Yoo, Young-Bok;Kong, Won-Sik;Jang, Kab-Yeul;Oh, Youn-Lee;Cheong, Jong-Chun
    • Journal of Mushroom
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    • v.11 no.2
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    • pp.77-81
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    • 2013
  • To develop a new cultivar of king oyster mushroom(Pleurotus eryngii), G09-21 as parental strain was selected by the method of Di-mon crossing between monokaryotic strain ASI 2824-21 derived from ASI 2824(Keunneutari No. 2) and dikaryotic strain ASI 2887(Aeryni 3). The Pe21-53(G09-21-10 x ASI 2844-9) was shown the best cultural characteristics, selected to be a new cultivar and designated as 'Seolsong'. The 'Seolsong' was distinctly formed incompatibility line in the confrontation growth of parental strains Keunneutari No. 2, Aeryni 3 and ASI 2844. Analysis of the genetic characteristics of the new cultivar 'Seolsong' showed a different DNA profile as that of the control strains, Keunneutari No. 2, Aeryni 3 and ASI 2844, when RAPD(Random Amplified Polymorphic DNA) primer URP4 was used. The optimum temperature and pH arrange for mycelial growth were $25{\sim}30^{\circ}C$ and pH 5~8, respectively. This new cultivar 'Seolsong' of fruiting body production per bottle was about $131.4{{\pm}}43.1$ g which is about 102% quantity compared to that of other cultivar Keunneutari No. 2. And also the stipe is thick and long, but the number of available stipe is few. Particularly, it was tolerant of high moisture above 90% during the growth period after primodia formation. We therefore expect that this new strain will save of labor and cost of cultivation by without culling work.

Pharmacokinetics of amoxicillin after intramuscular injection at different temperatures to cultured olive flounder, Paralichthys olivaceus (Amoxicillin의 근육투여에 따른 수온별 넙치 체내 약동학적 특성)

  • Kim, Ji-Soo;Lee, Ji-Hoon;Lee, Soo-Jin;Park, Kwan-Ha
    • Journal of fish pathology
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    • v.28 no.1
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    • pp.43-51
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    • 2015
  • The pharmacokinetic properties and residue levels of amoxicillin (AMOX) were studied after intramuscular injection to cultured olive flounders ($100{\pm}50g$), Paralichthys olivaceus. For pharmacokinetic studies, AMOX of 20 to 80 mg/kg body weight was administered at $17{\pm}2^{\circ}C$ or $22{\pm}2^{\circ}C$ and AMOX concentrations were determined in plasma, the liver, and the kidney by HPLC-UVD. Plasma samples were assessed at 0.25, 0.5, 1, 3, 6, 12, 24, 48, 72, 96, 168 hours post-dose, whereas liver and kidney concentrations were measured at 0.25 to 48 hours post-dose. The kinetic profiles of AMOX were analyzed by fitting to a 2-compartmental model with PKSolver program. The following parameters were obtained for a single dosage of 20, 40 and 80 mg/kg of body weight at $22^{\circ}C$ and 20 and 40 mg/kg of body weight at $17^{\circ}C$ in plasma, liver and kidney, respectively: $C_{max}$ (the peak concentration)= $27.23-257.36{\mu}g/m{\ell}$, $5.49-41.65{\mu}g/g$, $16.75-129.31{\mu}g/g$; $t_{max}$ (the time for peak concentration)= 0.05-0.91, 1.36-3.28, 1.95-4.49 h. For residue studies, AMOX of 40 and 400mg/kg was administered, and muscle samples were taken at 2, 5, 7, 14 and 21 days post-dose. The residueof AMOX in the muscle were found under the MRLs (maximum residue levels) within 7 days for the two doses.

Fish Fauna and Weight-Length Relationships for 9 Fish Species in Andong Reservoir (안동호의 어류상과 9개 어종의 길이-무게 상관관계에 관한 연구)

  • Han, Seung-Cheol;Lee, Hak-Yeong;Seo, Eul-Won;Shim, Jae-Hun;Lee, Jong-Eun
    • Journal of Life Science
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    • v.17 no.7 s.87
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    • pp.937-943
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    • 2007
  • The fish fauna and weight-length relationship in Andong reservoir were investigated from May 2005 to March 2006. During surveyed period, 2,540 individuals 20 species belonging to 7 families were collected. Dominant species were Hemibarbus labeo(19.6%) and sub-dominant species were Carassius cuvieri (19.2%). The korea endemic species were Hemiculter eigenmanni(7.1%), Squalidus chankaensis tsuchigae (0.1 %), Corroperca herzi (0.1 %) and introduced fishes were Carassius cuvieri (19.21 %) Lepomis macrochirus (4.2%), Micropterus salmoides (0.2%). Dominace, species diversity, species richness, species even-ness were 0.39, 3.16, 2.42, 0.73 respectively. The values of the exponent b in the weight-length relation-ship $W=aL^{b}$ ranged from 2.9162(H. labeo, $R^{2}$=0.9567) to 3.2509(Zacco pla쇼pus, $R^{2}$=0.9928) and the median value was 3.1079, whereas 50% of the values ranged between about 3.05 to 3.20. The Condition factor(K) showed good state of health in the surveyed species (excepts H. labeo and Cyprinus carpio).

Development of Biomass Allometric Equations for Pinus densiflora in Central Region and Quercus variabilis (중부지방소나무 및 굴참나무의 바이오매스 상대생장식 개발)

  • Son, Yeong-Mo;Lee, Kyeong-Hak;Pyo, Jung-Kee
    • Journal of agriculture & life science
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    • v.45 no.4
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    • pp.65-72
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    • 2011
  • The objective of this research is to develop biomass allometric equation for Pinus densiflora in central region and Quercus variabilis. To develop the biomass allometric equation by species and tree component, data for Pinus densiflora in central region is collected to 30 plots (70 trees) and for Quercus variabilis is collected to 15 plots (32 trees). This study is used two independent values; (1) one based on diameter beast height, (2) the other, diameter beast height and height. And the equation forms were divided into exponential, logarithmic, and quadratic functions. The validation of biomass allometric equations were fitness index, standard error of estimate, and bias. From these methods, the most appropriate equations in estimating total tree biomass for each species are as follows: $W=aD^b$, $W=aD^bH^c$; fitness index were 0.937, 0.943 for Pinus densiflora in central region stands, and $W=a+bD+cD^2$, $W=aD^bH^c$; fitness index were 0.865, 0.874 for Quercus variabilis stands. in addition, the best performance of biomass allometric equation for Pinus densiflora in central region is $W=aD^b$, and Quercus variabilis is $W=a+bD+cD^2$. The results of this study could be useful to overcome the disadvantage of existing the biomass allometric equation and calculate reliable carbon stocks for Pinus densiflora in central region and Quercus variabilis in Korea.

A Study on Design Optimization of an Axle Spring for Multi-axis Stiffness (다중 축 강성을 위한 축상 스프링 최적설계 연구)

  • Hwang, In-Kyeong;Hur, Hyun-Moo;Kim, Myeong-Jun;Park, Tae-Won
    • Journal of the Korean Society for Railway
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    • v.20 no.3
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    • pp.311-319
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    • 2017
  • The primary suspension system of a railway vehicle restrains the wheelset and the bogie, which greatly affects the dynamic characteristics of the vehicle depending on the stiffness in each direction. In order to improve the dynamic characteristics, different stiffness in each direction is required. However, designing different stiffness in each direction is difficult in the case of a general suspension device. To address this, in this paper, an optimization technique is applied to design different stiffness in each direction by using a conical rubber spring. The optimization is performed by using target and analysis RMS values. Lastly, the final model is proposed by complementing the shape of the weak part of the model. An actual model is developed and the reliability of the optimization model is proved on the basis of a deviation average of about 7.7% compared to the target stiffness through a static load test. In addition, the stiffness value is applied to a multibody dynamics model to analyze the stability and curve performance. The critical speed of the improved model was 190km/h, which was faster than the maximum speed of 110km/h. In addition, the steering performance is improved by 34% compared with the conventional model.