• Journal of the Korea Computer Graphics Society
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• v.29 no.3
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• pp.127-135
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• 2023

Accurate segmentation of histopathology whole slide images (WSIs) is a crucial task for disease diagnosis and treatment planning. However, conventional automated segmentation algorithms may not always be applicable to WSI segmentation due to their large size and variations in tissue appearance, staining, and imaging conditions. Recent advances in interactive segmentation, which combines human expertise with algorithms, have shown promise to improve efficiency and accuracy in WSI segmentation but also presented us with challenging issues. In this paper, we propose a novel interactive segmentation method, ZoomISEG, that leverages multi-resolution WSIs. We demonstrate the efficacy and performance of the proposed method via comparison with conventional single-scale methods and an ablation study. The results confirm that the proposed method can reduce human interaction while achieving accuracy comparable to that of the brute-force approach using the highest-resolution data.

• KIPS Transactions on Computer and Communication Systems
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• v.11 no.7
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• pp.233-240
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• 2022

Most of the recent AI researches has focused on developing AI models. However, recently, artificial intelligence research has gradually changed from model-centric to data-centric, and the importance of learning data is getting a lot of attention based on this trend. However, it takes a lot of time and effort because the preparation of learning data takes up a significant part of the entire process, and the generation of labeling data also differs depending on the purpose of development. Therefore, it is need to develop a tool with various labeling functions to solve the existing unmetneeds. In this paper, we describe a labeling system for creating precise and fast labeling data of medical images. To implement this, a semi-automatic method using Back Projection, Grabcut techniques and an automatic method predicted through a machine learning model were implemented. We not only showed the advantage of running time for the generation of labeling data of the proposed system, but also showed superiority through comparative evaluation of accuracy. In addition, by analyzing the image data set of about 1,000 patients, meaningful diagnostic indexes were presented for men and women in the diagnosis of sarcopenia.

• Journal of the Korean Society of Radiology
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• v.7 no.1
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• pp.9-15
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• 2013

In this study, texture feature analysis (TFA) algorithm to automatic recognition of liver disease suggests by utilizing computed tomography (CT), by applying the algorithm computer-aided diagnosis (CAD) of hepatocellular carcinoma (HCC) design. Proposed the performance of each algorithm was to comparison and evaluation. In the HCC image, set up region of analysis (ROA, window size was $40{\times}40$ pixels) and by calculating the figures for TFA algorithm of the six parameters (average gray level, average contrast, measure of smoothness, skewness, measure of uniformity, entropy) HCC recognition rate were calculated. As a result, TFA was found to be significant as a measure of HCC recognition rate. Measure of uniformity was the most recognition. Average contrast, measure of smoothness, and skewness were relatively high, and average gray level, entropy showed a relatively low recognition rate of the parameters. In this regard, showed high recognition algorithms (a maximum of 97.14%, a minimum of 82.86%) use the determining HCC imaging lesions and assist early diagnosis of clinic. If this use to therapy, the diagnostic efficiency of clinical early diagnosis better than before. Later, after add the effective and quantitative analysis, criteria research for generalized of disease recognition is needed to be considered.

• Journal of Software Engineering Society
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• v.28 no.1
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• pp.13-22
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• 2019

To enhance effective and efficient applications of automated security vulnerability checkers in highly competitive and fast-evolving IT industry, this paper studies a comprehensive set of security bug checkers in open-source static analysis frameworks and how they can be utilized for source code inspections according to the security vulnerability inspection guidelines by MOIS. This paper clarifies the relationship be tween all 42 inspection criteria in the MOIS guideline and total 323 security bug checkers in 4 popular open-source static analysis frameworks for Java web applications. Based on the result, this paper also discuss the current challenges and issues in the MOIS guideline, the comparison among the four security bug checker frameworks, and also the ideas to improve the security inspection methodologies using the MOIS guideline and open-source static security bug checkers.

• The Journal of Korean Academy of Prosthodontics
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• v.59 no.3
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• pp.299-304
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• 2021

Purpose. The purpose of the present study was to investigate the effects of image matching experience of operators on the accuracy and working time of image registration between radiographic and optical scan images. Materials and methods. Computed tomography and optical scan of a dentate dental arch were obtained. Image matching between the computed tomography and the optical scan (IDC S1, Amann Girrbach, Koblah, Austria) was performed using the point-based automatic registration method in planning software programs (Implant Studio, 3Shape, Copenhagen, Denmark) using two different experience conditions on image registration: experienced group and inexperienced group (n = 15 per group, N = 30). The accuracy of image registration in each group was evaluated by measuring linear discrepancies between matched images, and working time was recorded. Independent t test was used to statistically analyze the result data (α = .05). Results. In the linear deviation, no statistically significant difference was found between the experienced and inexperienced groups. Meanwhile, the working time for image registration was significantly shorter in the experienced group than in the inexperienced group (P = .007). Conclusion. Difference in the image matching experience may not influence the accuracy of image registration of optical scan to computed tomography when the point-based automatic registration was used, but affect the working time for the image registration.

• Journal of KIISE:Computer Systems and Theory
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• v.32 no.10
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• pp.530-540
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• 2005

Virtual colonoscopy is an easy and fast method to reconstruct the shape of colon and diagnose tumors inside the colon based on computed tomography images. This is a non-invasive method, which resolves weak points of previous invasive methods. The path for virtual colonoscopy should be generated rapidly and accurately for clinical examination. However, previous methods are computationally expensive because the data structure such as distance map should be constructed in the preprocessing and positions of all the points of the path needs to be calculated. In this paper, we propose the automatic path generation method based on visibility to decrease path generation time. The proposed method does not require preprocessing and generates small number of control points representing the Path instead of all points to generate the path rapidly. Also, our method generates the path based on visibility so that a virtual camera moves smoothly and a comfortable and accurate path is calculated for virtual navigation. Also, our method can be used for general virtual navigation of various kinds of pipes.

• Journal of the Korea Computer Graphics Society
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• v.23 no.1
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• pp.49-55
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• 2017

Computed tomographic angiography (CTA) is widely used in the diagnosis and treatment of coronary artery disease because it shows not only the whole anatomical structure of the cardiovascular three-dimensionally but also provides information on the lesion and type of plaque. However, due to the large size of the image, there is a limitation in manually extracting coronary arteries, and related researches are performed to automatically extract coronary arteries accurately. As the coronary artery originate from the ascending aorta, the ascending aorta and ostium should be detected to extract the coronary tree accurately. In this paper, we propose an automatic segmentation for the ostium as a starting structure of coronary artery in CTA. First, the region of the ascending aorta is initially detected by using Hough circle transform based on the relative position and size of the ascending aorta. Second, the volume of interest is defined to reduce the search range based on the initial area. Third, the refined ascending aorta is segmented by using a two-dimensional geodesic active contour. Finally, the two ostia are detected within the region of the refined ascending aorta. For the evaluation of our method, we measured the Euclidean distance between the result and the ground truths annotated manually by medical experts in 20 CTA images. The experimental results showed that the ostia were accurately detected.

• Journal of Korea Multimedia Society
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• v.14 no.3
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• pp.348-355
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• 2011

In this paper, we propose an automatic prostate segmentation method from dynamic magnetic resonance (MR) images. Our method detects contrast-enhanced images among the dynamic MR images using an average intensity analysis. Then, the candidate regions of prostate are detected by the B-spline non-rigid registration and subtraction between the pre-contrast and contrast-enhanced MR images. Finally, the prostate is segmented by performing a dilation operation outward, and sequential shape propagation inward. Our method was validated by ten data sets and the results were compared with the manually segmented results. The average volumetric overlap error was 6.8%, and average absolute volumetric measurement error was 2.5%. Our method could be used for the computer-aided prostate diagnosis, which requires an accurate prostate segmentation.

• Journal of the Korean Institute of Telematics and Electronics C
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• v.36C no.12
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• pp.90-97
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• 1999

Recently, there have been many researches to automate processing and analysing image data in medical field, due to the advance of image processing techniques, the fast communication network and high performance hardware. In this paper, we design and implement the system based on the multi-layer neural network model to be able to analyze, differentiate and count blood cells in the peripheral blood image. To do these, we segment red and white-blood cell in blood image acquired from microscope with CCD(Charge-coupled device) camera and then apply the various feature extraction algorithms to classify. In addition to, we reduce multi-variate feature number using PCA(Principle Component Analysis) to construct more efficient classifier. So, in this paper, we are sure that the proposed system can be applied to a pathological guided system.

• The Journal of Society for e-Business Studies
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• v.19 no.4
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• pp.45-60
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• 2014

Dentist can obtain 3D anatomical information without distortion and information loss by using dental Computed Tomography scan images on line, and also can make the preoperative plan of implant placement or orthodontics. It is essential to segment individual tooth for making an accurate diagnosis. However, it is very difficult to distinguish the difference in the brightness between the dental and adjacent area. Especially, the root of a tooth is very elusive to automatically identify in dental CT images because jawbone normally adjoins the tooth. In the paper, we propose a method of automatically tooth region segmentation, which can identify the root of a tooth clearly. This algorithm separate the tooth from dental CT scan images by using Seeded Region Growing method on dental crown and by using Level-set method on dental root respectively. By using the proposed method, the results can be acquired average 19.2% better accuracy, compared to the result of the previous methods.