• Title/Summary/Keyword: 침투정

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The Study for Stability of Useful Glycyrrhiza uralensis (Licorice Root) Using Nanosolve and PMMA (Nanosolve와 PMMA를 이용한 유용성감초산의 안정화에 대한 연구)

  • Ji, Hong-Geun;Kim, Ju-Duck;Kim, Jeong-Dong;Choi, Jung-Sik
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.2
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    • pp.207-210
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    • 2004
  • Glycyrrhiza uralensis (licorice root) is very useful medicinal herb because of strong anti-inflammatory and anti-wrinkle effect. Therefore, it is widely used in functional cosmetics. However, it is insoluble and easily decomposed by light, heat, oxygen, etc. In this study, we first prepared NanoSolve-Licorice (30-50nm) using Glycyrrhiza uralensis and propylene glycol! hydrogenated lecithin/caprylic/capric triglyceride/glycerin/water system with microfluidizer. And then, NanoSolve-Licorice and porous PMMA are dispersed in ethanol. Finally, we could get a stabilized system with high-pressure homogenizer (1,000 Bar, 3 passes). According to HPLC measurement for glabridin content, our system is more stable compared with general liposome ones. Capsulated licorice has an enhanced anti-inflammatory effect on account of excellent skin penetration. We also evaluated our final product through image analyzer, particle size analyzer, FF-TEM and chromameter.

Relation of the Activities of Plasminogen Activator and Plasmin-like Protease with Malignant Behavior of Skin Tumor of Rats (Plasminogen Activator 및 Plasmin-like Protease활성도의 변화와 쥐 피부암의 악성)

  • Yun Kee;Park, Sang C.;Doo B. Ha;Chin H. Chung
    • The Korean Journal of Zoology
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    • v.31 no.3
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    • pp.185-190
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    • 1988
  • To investigate whether malignant behavior of skin tumor correlates with changes in the level of proteolytic activities in skin tumors, rats were treated with 7,12-dimethylbenzanthracene followed by photbor ester. Tumors induced upon the treatrnents exhibited more than 20-fold increase in the activity of plasminogen activator and about 3-fold of plasmin-like activity. as compared to those in treated controls. Furthermore, the former activity was raised to about 6-fold even in the preneoplastic dssues of the skin tissues. On the other hand, the proteolytic activity against casein and insulin decreased to several-fold in the tumor tissues while antitrvpsin activity remained similar in both tumor and controls. Thus, the increase in the activities of plasmInogen activator and plasminlike enzyme appears to occur as a charaderistic to skin cancer and may involve in invasion and metsstasis of the tumor.

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Basic Study on the Performance of a Pressure-difference Control Damper Affected by Flow Disturbance in a Wind Tunnel (풍도 내 유동 교란과 자동차압 댐퍼의 성능 특성 기초 연구)

  • Yun, Yung-Min;Lee, Min-Jung;Kim, Nam-Il;Ryou, Hong-Sun
    • Fire Science and Engineering
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    • v.23 no.6
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    • pp.16-23
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    • 2009
  • The performance characteristics of a smoke damper, which aims to suppress the penetration of smoke to a safe area, have been tested under the regulation of the FIS 001. However, the improvement of the test methods and the regulation has consecutively been requested. From a view-point of fluid mechanical theory, a pressure control damper, that is installed at the end of the flow control system, is important and it dominates flow characteristics in all designed flow systems. In this study, the weak points of the regulation of the FIS 001 concerned with the pressure control damper was visited and the some important characteristics of the damper was examined. Based on these results, it was confirmed that the effects of flow disturbance in the air supplying duct on the performance of the damper are not significant. This results gives some information for the modification of the experimental regulation concerned to the pressure control damper.

Estimation of irrigation water need with climate change in Jeju Island (기후변화에 따른 제주도 농업용수 수요량 변화 추정)

  • Kim, Chul-Gyum;Kim, Nam-Won;Cho, Jaepil
    • Proceedings of the Korea Water Resources Association Conference
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    • 2017.05a
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    • pp.459-459
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    • 2017
  • 본 연구에서는 순물소모량 개념의 농업용수 수요량 추정방법을 적용하여 기후변화에 따른 제주도의 미래 수요량 변화를 추정 분석하였다. 지하수를 주 수원으로 하고 관정에 의한 밭작물 위주의 작물재배와, 일정 규모 이상의 강우시에만 유출이 발생하며, 유출량의 대부분이 지하수로 침투되는 물순환 특성 등을 고려할 수 있는 제주도 지역에 적합한 순물소모량 산정방법을 적용하였다. 순물소모량 산정에 필요한 실제증발산량 및 잠재증발산량 등은 유역모형인 SWAT을 이용하여 산정하였다. SWAT 모형의 구동에 필요한 미래 기후자료는 10개의 대표적인 대순환모델(General Circulation Model, GCM) 결과로부터 상세화(Downscaling) 기법을 통해 적용하였으며, RCP 4.5와 RCP 8.5 시나리오를 중심으로 미래 기후변화에 따른 영향을 분석하였다. 미래(2010-2099)의 수문성분별 변화를 살펴본 결과, 연도별 증감과 GCM 모델별 차이는 있으나, 평균적으로 강수량, 잠재증발산량, 실제증발산량, 함양량 등이 점차 증가하는 것으로 나타났으며, RCP 4.5보다는 RCP 8.5 시나리오에서 증가현상이 좀 더 크게 나타났다. 순물소모량 또한 2010년에 비해 2099년을 기준으로 약 100~200mm 정도 증가하는 것으로 나타났으며, RCP 8.5 시나리오에서 증가폭이 크게 나타났다. 그러나 이는 자연적인 기후변화에 따른 단위면적당 순물소모량으로서, 인위적인 요인인 농업형태의 변화(관개면적의 증감, 작물품종의 변화, 인위적 용수절감 등)에 따라 실제 지역별 농업용수 수요량은 다른 경향을 나타낼 수도 있다. 특히 농업용수는 계절별, 지역별 편차가 크게 나타나므로, 자연적 조건에 의한 가용수자원량과 지역별 공급시설에 의한 용수공급량 및 수요예측량의 상호분석을 통해 안정적 물수급을 위한 대응책 마련이 필요할 것으로 판단된다.

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Gamification Convergence Contents Study: Formal Elements of the Game Implemented in (게이미피케이션 융합콘텐츠 연구: <잼라이브>에 나타난 게임의 형식적 요소를 중심으로)

  • Lee, Un-Jung;BYUN, Daniel H.
    • The Journal of the Korea Contents Association
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    • v.19 no.8
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    • pp.483-489
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    • 2019
  • Recently, various media such as broadcasting, movies, and mobile converge with game elements, expanding the contents and expanding the area. This study focuses on the gamification convergence contents. Among them, we examine the case of mobile application live quiz show by applying the formal elements of the game mentioned by Tracy Fullerton. The elements have all the formal elements of the game, which led to the conclusion that they lead the audience to immersion based on the play characteristics of the game. This can be attributed to the elements of the game that have penetrated into the contents, and it can be reinterpreted, and the directions of new contents can be presented, which is industrially, culturally and academically significant. This study focuses on the industrial and cultural achievements created by contents, and plans and prospects new content that balances play and usefulness.

Performance of a Chimney Drain in Reinforced Earth Wall for Reduction of Pore Water Pressure During Rainfall - a Numerical Investigation (보강토 옹벽에 적용되는 연직 배수시스템의 강우시 수압 저감 효과 - 수치해석 연구)

  • Yoo, Chung-Sik;Kim, Sun-Bin;Jung, Hyuk-Sang
    • Journal of the Korean Geotechnical Society
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    • v.24 no.5
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    • pp.99-106
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    • 2008
  • This study is concernsed with the effect of a chimney drainage system installed at the back of reinforced soil block on preventing the pore water pressure development. A series of finite-element analyses based on transient seepage analysis were performed for a number of cases with different patterns of the chimney drainage system. The results were thoroughly analyzed to get insight into the mechanism of pore water pressure reduction effect of the chimney drainage system. It is shown that a vertical drainage system installed at the back of reinforced zone can be an effective means of maintaining the wall stability during rainfall by preventing pore pressure increase in the reinforced as well as the backfill zones. Also shown is that the optimum height of the chimney drain is 50% of the wall height. Practical implications of the findings were discussed.

Effect of Steel Fiber Addition on the Mechanical Properties and Durability of High-Flowable Retaining Wall Material (고유동 흙막이 벽체 재료의 역학적 성능 및 내구성에 대한 강섬유 혼입률의 영향)

  • Donggyu Kim;Seungtae Lee
    • Journal of the Korean GEO-environmental Society
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    • v.24 no.6
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    • pp.13-20
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    • 2023
  • This paper is aimed to evaluate the mechanical properties and durability of high-flowable retaining wall material (RWM) with different levels of steel fiber (SF) content. To produce the specimens of RWM, some chemical agents such as superplasticizer (SP), air-entrained agent (AEA) and viscosity modifying agent (VMA) were added in the fresh RWM. The compressive and split tensile strength measurements were performed on the hardened RWM specimens at the predetermined periods. Additionally, surface electric resistivity and absorption tests according to ASTM standards were carried out to examine mechanical properties of RWM mixes. The durable performances such as chloride ions penetrability and freezing-thawing resistance of RWM mixes were experimentally investigated. As resutls, it was found that the performance of RWM mix with SF were much better than that without SF, especially at the 2% addition of SF. Thus, it is noted that the proper addition of SF in the RWM mix may have a beneficial effect to improve mechanical properties and durability of RWM mixes.

Effects of Some Factors on In Vitro Production of Embryos from Antral Follicle-Derived Porcine Oocytes III. Effects of Fertilization Media and the Sperm Concentration during Fertilization on In Vitro Fertilization and Development (돼지 난포란 유래 체외수정란 생산에 대한 제요인의 영향 III. 체외수정배양액과 정자농도가 체외수정 및 체외발달에 미치는 영향)

  • Yeon S. H.;Son D. S.;Jean H. J.;Choi S. H.;Kim I. C.;Park C. S.;Lee K. S.
    • Journal of Embryo Transfer
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    • v.19 no.3
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    • pp.265-273
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    • 2004
  • This study was carried out to examine the effects of fertilization media and sperm concentration on in vitro fertilization (IVF) and development (IVD) of porcine oocytes matured in vitro. Cumulus-oocyte complexes (COCs) were collected from antral follicles of porcine ovaries collected from abattoir, and were matured in vitro in modified NCSU-23 (mNCSU-23) supplemented with 10% porcine follicular fluid (pFF). After the fertilization by experimental scheme, putative embryos were developed in vitro in NCSU-23. The results are as follows. When the oocytes were fertilized in vitro in modified TBM or modified TLP-PVA by 1 ${\times}$10$^{5}$ sperm/$m\ell$, all of the fertilization parameters were not significantly different between two media. Subsequently, as these putative embryos were developed in vitro in NCSU-23, the percentage of oocytes cleaved and of blastocysts were not different between two media, either. When the oocytes were fertilized in vitro in mTBM by 5${\times}$10$^4$, 1${\times}$10$^{5}$ or 5${\times}$10$^{5}$ sperm/$m\ell$, all of the fertilization parameters were significantly (P<0.05 or P<0.01) increased as sperm concentration was elevated. Subsequently, as these putative embryos were developed in vitro in NCSU-23, the percentage of oocytes cleaved and of blastocysts were significantly boosted (P<0.01) as sperm concentration at fertilization was elevated from 5${\times}$10$^4$ to 1${\times}$10$^{5}$ sperm/$m\ell$, but were not different between 1${\times}$10$^{5}$ and 5${\times}$10$^{5}$ sperm/$m\ell$.

The Effects of Geological and Topographical Features on Landslide and Land-creep (지질(地質)과 지형(地形)이 산사태(山沙汰) 및 땅밀림에 미치는 영향(影響))

  • Jau, Jae-Gyu;Park, Sang-Jun;Son, Doo-Sik;Joo, Sung-Hyun
    • Journal of Korean Society of Forest Science
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    • v.89 no.3
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    • pp.323-334
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    • 2000
  • This study was carried out to investigate the effects of geological and topographical features on landslide and land-creep at the twenty four surveyed sites of Kyungpook province. According to the results obtained, it was concluded that continuous heavy rainfall was one of the primary factors to occur landslide and land-creep. Most of the landslides occurred in the past were concentrated in the granite and granitic gneiss zones, while land-creeps were mainly occurred in the mud-stone zones. Therefore, it was thought that the physical properties such as soil texture, solid phase, moisture contents, density, hardness and porosity rate of weathered granite and granitic gneiss could affect the occurrence of landslide and land-creep. Due to the holding of sand contents in the upper soil layers of weathered granite and granitic gneiss, rainfall could infiltrate into the soil easily. While lower soil layers contained much quantity of clay and silt contents, those soils saturated with rainfall cause to lose viscosity and shear strength. Therefore, it was seemed that landslide was occurred more easily and the saturation of those soils was made much easily by bed rocks under those soils. Landslide and land-creep are slided into lower place by gravitation and slope degree factors. Therefore, prediction of landslide occurrence is very difficult because landslide is occurred abruptly, and physical properties of the soil have to be understood and checking the existence of bed rocks under the soils is not easy, on the other hand, land-creep is progressed very slowly. Therefore, it was suggested that in a degree creeping could be protected by removing of several causing factors.

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Behavior of Concrete Bridge Deck Using Hybrid Reinforcement System (Hybrid Reinforcement System을 이용한 콘크리트 교량상판 슬래브의 거동)

  • Park Sang-Yeol;Cho Keun-Hee
    • Journal of the Korea Concrete Institute
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    • v.16 no.4 s.82
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    • pp.451-458
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    • 2004
  • This study describes the basic concept and the applicability of Hybrid Reinforcement System using conventional steel reinforcing bars and Fiber Reinforced Polymer bars. The concrete bridge decks are assumed to be supported by beams and reinforced with two layers of reinforcing bars. In concrete bridge deck using HRS, the top tensile force for negative moment zone on beam supports is assumed to be resisted by FRP reinforcing bars, and the bottom tensile force for positive moment zone in the middle of hem supports is assumed to be resisted by conventional steel reinforcing bars, respectively. The FRP reinforcing bars are non-corrosive. Thus, the steel reinforcement is as far away as possible from the top surface of the deck and protected from intrusion of corrosive agent. HRS concrete bridge deck has sufficient ductility at ultimate state as the following reasons; 1) FRP bars have lower elastic modulus and higher ultimate strain than steel re-bars have, 2) FRP bars have lower ultimate strain if provided higher reinforcement ratio, 3) ultimate strain of FRP bars can be reduced if FRP bars are unbonded. Test results showed that FRP and HRS concrete slabs are not failed by FRP bar rupture, but failed by concrete compression in the range of ordinary reinforcement ratio. Therefore, in continuous concrete bridge deck using HRS, steel reinforcing bars for positive moment yield and form plastic hinge first and compressive concrete fail in the bottom of supports or in the top of the middle of supports last. Thus, bridge deck consumes significant inelastic strain energy before its failure.