During pregnancy, maternal immune activation (MIA) from infection increases the risk of neurodevelopmental diseases, including schizophrenia and autism spectrum disorders. MIA induced by polyinosinic-polycytidylic acid (poly (I:C)) and lipopolysaccharide (LPS) in animal experiments has led to offspring with abnormal behaviors and brain development. In addition, it has recently been reported that microglia, which reside in the brain and function as immune cells, play an important role in behavioral abnormalities and brain development in MIA-induced offspring. However, the underlying mechanism remains unclear. In this study, we investigated whether microglia-specific inhibition of GPR56, a member of the G protein-coupled receptor (GPCR) family, causes behavioral abnormalities in brain development. First, MIA induction did not affect the microglia population, but when examining the expression of microglial GRP56 in MIA-induced fetuses, GPR56 expression was inhibited between embryonic days 14.5 (E14.5) and E18.5 regardless of sex. Furthermore, microglial GPR56-suppressed mice showed abnormal behaviors in the MIA-induced offspring, including sociability deficits, repetitive behavioral patterns, and increased anxiety levels. Although abnormal cortical development such as that in the MIA-induced offspring were not observed in the microglial GPR56-suppressed mice, their brain activity was observed through c-fos staining. These results suggest that microglia-specific GPR56 deficiency may cause abnormal behaviors and could be used as a biomarker for the diagnosis and/or as a therapeutic target of behavioral deficits in MIA offspring.
The Journal of the Convergence on Culture Technology
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v.9
no.2
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pp.437-444
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2023
With the development of modern society, society provides people with a quick and convenient life, but it also causes anxiety, depression, other psychological and mental illnesses, so art can also be used as a way and path to treating psychological disorders. Art therapy is a creative method of delivery used in therapy, resulting from the fusion of art and psychotherapy. Art is a service and public art activity, mainly aimed at solving human psychological problems, providing nonverbal expression and communication opportunities, and treating psychological and psychological entanglement by improving emotion, stability, and indirectly inappropriate behavior through multi-disciplinary convergence. Art therapy, as an independent discipline, began in Europe in the 3rd and 40th centuries and was mainly influenced by two psychologists, Sigmund Freud and Carl (Gustav Jung). We Starting with the theoretical foundation of psychoanalysis, this paper explores the effectiveness of modern people's psychotherapy, analyzes the similarities between the two ideas, explores the application of art therapy and the development of science and technology, and provides the public with various ways of art therapy and the validity of science and technology.
Journal of Korea Entertainment Industry Association
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v.13
no.7
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pp.25-38
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2019
For many years, emotions have been regarded as dangerous as well as obstructive to reason and rationality. Even in the history of dramatic genres based on human behavior, emotions are often portrayed as errors or flaws that lead to the collapse of characters, even though they are presented as powerful motives to evoke the characters' actions. Based on the development of the cognitive science field today, it is revealed how emotion is important for human thinking, judgment and action, and how closely reason and emotion are combined. This study examines emotions dealt with in drama genres on the basis of the sociality of emotions. Emotions also play a crucial role in the change and judgment of the audience of drama. This study examines the sociality of emotions and looks at the social aspect of individual emotions through the movie as a text. Just as horror movies attempt to communicate using and expanding feelings of fear, the movie uses the emotions of 'Sad' and 'Losing' to try to expand and share it. And I look into the mechanism in which the emotions of the characters in drama are transmitted to the audience in the form of empathy.
Disabled elderly faced with disability and the aged problems at the same time. So, this research creates two research questions and examines. First research question is how nine dimensions of daily life satisfaction according to gender difference. Second research question is how the factor of daily life satisfaction by gender difference. The data is sixty-five disabled elderly, 386 among Panel Survey of Employment for the Disabled(PSED, 2008). The methods of analysis for identifying research questions is t-test and multiple linear regression. The result of analysis on first research question, the gender difference six dimensions among nine dimensions of daily life satisfaction come out statistically significant. And The result of analysis on second research question, come out statistically significant, too. Socioeconomic status: the lower class, physical condition: bad health, chronic disease is or not, family and other people's social supports, disability: serious turn out to be factors in common. It has been suggested social policies from the results of studies that the provision of health support policy and program, enlarge assistance on daily life, support system on serious disabled elderly. On the other hand, analysis showed that distinctive factors between disabled elderly man and woman was age and education level. In other words, disabled elderly woman come out into the open that the more grow old, the less daily life satisfaction low, while disabled elderly man appeared higher daily life satisfaction in case of junior and senior high school graduate than uneducated.
The purpose of this study was to search the clustering and variables in discriminating the groups by the level of the loss experience and ego-integrity among the elderly. In addition, the study aimed to confirm the moderating effects of variables related to resilience in the relationship between a loss experience and ego-integrity. The subjects were 245 elderly aged 60 or above, most of whom were socially active with comparatively high education levels. Six individual variables(physical self-efficacy, general self-efficacy, social self-efficacy, existential spirituality, religious spirituality, optimism) and five environmental variables(emotional support, instrumental support, informational support, appraisal support, social activity) were used in the study. The results of the study are as follows. To data analysis, ANOVA, Stepwise Discriminant analysis, Cluster analysis, Regression analysis and Two-way analysis of variance was employed. First, the subjects were 4 cluster into overcome group, crisis group, stable group and vulnerable group according to the level of loss experience and ego-integrity. Second, optimism, physical self-efficacy, existential spirituality and emotional support were seen to be significant variables in discriminating the groups. Third, the ego-integrity became higher as the variables related to resilience were increased.
Materialistic values can be a important variable to understand Koreans' psychological well-being and mental health. This study aimed to validate the Korean version of the Material Values Scale (K-MVS)(Richins & Dawson, 1992). In study 1, we performed confirmatory factor analysis(CFA) to ascertain the three factor model of the original MVS using 417 Korean undergraduate student data(sample 1). The CFA confirmed the three-factor model of the MVS. Yet, three items that yielded low factor loadings in this study as well as in other MVS validation studies were excluded from the final model. In study 2, content, construct, and concurrent validity of the K-MVS were examined with 650 undergraduate student data(Sample 2). We also tested measurement invariance across two groups(i.e., college student group of Sample 2 and employee group of Sample 3). The result revealed that the three-factor model of the K-MVS hold true across the two groups. Lastly test-retest reliability was calculated with 408 female college student data(Sample 4) that filled out K-MVS twice within 6 months. These findings suggest that the K-MVS is a reliable and valid measure for assessing materialistic values in Korea.
This paper explored the differences in university students' e-Sports patterns(e-Sports behaviors, its meaning and personalities) based on the types of game-lifestyle. The results of this study could be summarized as follows. First, game-lifestyle was categorized into 5 groups, that is, 'game with someone', 'game alone', 'addicted to game', 'novice for game' and 'flow in game'. Second, there were remarkable differences in e-Sports behaviors, its meaning and personalities(altruism, sociality and aggression) among these 5 groups. Specifically, The group of 'addicted to game' was similar to the group of 'flow in game' in the amount of time/money for game. Moreover they were highly likely to regard e-Sports game defeat as the reflection of their self-esteem and as the tool of gaining popularity/superiority to peers. Even though these similarities, the group of 'flow in game' was inclined not to permit deviant words/deeds and to keep the good manner in the cyber space as well as the real space, while the group of 'addicted to game' was permissible wrong and aggressive behaviors in the both cyber space and real space. Third, the group of 'novice for game' was less likely to participate in e-Sports activities(playing e-Sports game and watching TV) and to be less attracted to e-Sports than other groups. Moreover they had negative perspectives on e-Sports. In specific, they regarded it as a dangerous and addictive leisure activity hindering everyday life(study, relationship with peers/family etc) and health. These results would be used to develop game/e-Sports education program
This study is a research study aimed at finding out the relationship between lifestyle and life satisfaction of single youth households and the relationship between the mediating role of interpersonal relationships and the effect of parents' social and economic status regulation in the relationship between lifestyle and life satisfaction. To this end, this study conducted a self-written survey of single-person youth households across the country through an online survey institution, regardless of gender, and used a total of 501 copies out of 520 subjects for final results analysis. The data were analyzed using the SPSS 25.0 and AMOS 25.0 programs, and the applied statistical techniques included correlation analysis, confirmatory factor analysis, structural equation model analysis, multi-group analysis, and bootstrap. As a result of the study, there was a significant positive (+) correlation between lifestyle, life satisfaction, and interpersonal relationships of single youth households, and interpersonal relationships were found to have a mediating effect in the relationship between lifestyle and life satisfaction. It was found to have a significant positive (+) effect on income and income satisfaction, but the moderating effect of education, economic activity, housing ownership type, and class consciousness was not significant. Based on the results of these studies, it was intended to provide basic data for developing various community programs and institutional arrangements for single youth households.
This article compares the psychological and behavioral profiles of adolescents on probation and high school students. A total of 253 adolescents on probation and 257 high school students completed an open-ended questionnaire developed by the present researchers and structured questionnaire that assessed moral disengagement and self-efficacy developed by Bandura (1995), delinquent behavior and academic achievement. Adolescents on probation reported that they engaged in delinquent behavior due to the fault of others and they were angry for being forced to be on probation. They are not likely to take responsibility and morally disengage from their delinquent actions. When compared to high school students, adolescents on probation are likely to report low self-efficacy, low academic grade, and less likely to feel proud of themselves. They are more likely to meet their friends in Internet and video game rooms and less likely to focus on academic achievement. Results of ANCOVA indicate that adolescents on probation have higher scores on moral disengagement, social efficacy, but lower score on efficacy for self-regulated learning. They are more likely to run away from home and have lower academic grade. The results of the discriminant analysis indicate that running away from home, social efficacy and moral disengagement are predictive of adolescents on probation and academic achievement and efficacy for self-regulated learning are predictive of high school students.
Asia-Pacific Journal of Business Venturing and Entrepreneurship
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v.17
no.2
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pp.153-165
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2022
The COVID-19 Pandemic incident forced all educational and learning activities to move online, so it is no longer an option to use information and communication technology for education and learning. Venture capital has made the largest investment ever in Edu-tech startups. This study investigates the factors influencing the intention to use digital technology in education, taking into account the Unified Theory of Acceptance and Use of Technology (UTAUT) along with digital literacy, which has become an essential ability in the digital age. As a result of the structural equation model analysis, we find that performance expectation, effort expectation, and social influence have a positive effect on the intention to use digital technology in education. Moreover, digital literacy has a positive effect on performance expectation, effort expectation, and social impact, but the direct effect on the intention to use digital technology on learning is not significant. Furthermore, to see the moderating effect of age, the results of multi-group analysis present that the differences between 10s and 60s, between 20s and 60s, between 30s and 60s on the path of social influence on the intention to use digital technology in education are significantly reduced. This study academically contributes to expanding the research on the factors affecting the intention to use digital technology in a specific situation of education by considering both digital literacy and Unified Theory of Acceptance and Use of Technology (UTAUT). In addition, it can be used as a practical guide to the factors to be considered for each age when making learning participants more actively use digital technology.
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