• Radiation Oncology Journal
• /
• v.18 no.4
• /
• pp.329-336
• /
• 2000

Backgrounds : The purpose of this study was to identify drugs that can enhance radioresponse of murine fepatocarcinorna. Methods : CSH/HeJ mice bearing 8 mm tumors of murine fepatocarcinorna, HCa-1, were treated with 25 Gy radiation and one of the following drugs: 5-Fu, 150 mghg; adriamycin, 8 mg/kg; cisplatin, 6 mg/kg; paclitaxel, 40 mg/kg; and gemcitabine, 50 mg/kg. Tumor response to the treatment was determined by tumor growth delay assay and by enhancement factor. Apoptotic level was assessed in tissue sections. Expression of regulating molecules was analyzed by western blotting for p53, Bcl-2, Bax, Bcl-XL, Bcl-XS, and p21$^{WAF1/CIP1}$. Results :Among the drugs tested, only gemcitabine enhanced the antitumor effect of radiation, with enhancement factor of 1.6. Induction of apoptosis by a combination of gemcitabine and radiation was shown as only additive level. In analysis of radiation-induced expression of regulating molecules, the most significant change by combining gemcitabine was activation of p21$^{WAF1/CIP1}$ Conclusion :Gemcitabine is the first drug showing an enhancement of radioresponse in murine hepatocarcinoma, when combined with radiation. The key element of enhancement is thought to be p21$^{WAF1/CIP1}$.

• Journal of KIISE:Databases
• /
• v.29 no.1
• /
• pp.34-43
• /
• 2002

Since traditional static metadata set like Dublin Core has static metadata attributes about bibliography information, integration of metadata for various metadata, problems about standard and extension of metadata must be considered for applying it to new environment. Specially, as event-driven metadata write method included the notion of e-commerce come out for interoperability in digital libraries, traditional metadata management which cannot distinguish between different kinds of update operations to new extension of metadata set occurs unsuitable waiting of update operation. So, improvement is needed about it. In this paper, we show whether alleviative transaction consistency can be applied to digital library or not. Also it would divide newer metadata into static metadata attribute connected in read operation within user read-only transaction and dynamic metadata attribute in update operation within dynamic(e-commerce) update transactions. We propose newer metadata management algorithm considered in classfication of metadata attributes and dynamic update transaction. Using two version for minimal maintenance cost and ARU(Appended Refresh Unit) for dynamic update transaction, to minimize conflict between read and write operations shows fast response time and high recency ratio. As a result of the performance evaluation, we show our algorithm is proved to be better than other algorithms in newer metadata environments.

• Journal of the Institute of Electronics Engineers of Korea SP
• /
• v.42 no.5 s.305
• /
• pp.137-144
• /
• 2005

In this paper, the extraction method of the edge histogram directly using wavelet coefficients in the wavelet domain for JPEG2000 images is proposed. MPEG-7 Edge Histogram Descriptor(EHD) extracts edge histogram in the spacial domain. This algorithm has much multiplication and addition for the edge extraction because it needs the decoding processing. However because the proposed algorithm extracts the edge histogram in the wavelet domain, it doesn't need the decoding processing and it decreases multiplication and addition. The Discrete Wavelet Transform(DWT) is a standard transform in JPEG2000. The proposed algorithm uses Le Gall 5/3 filter in JPEG2000 and odd coefficients in LH2 and HL2 sub-band. The edge direction can be decided to use rate of HL2 and LH2 odd coefficients. According to experiments, there is no difference of the efficiency between EHD and the proposed algorithm And the proposed algorithm is much better than EHD for multiplication and addition in the edge extraction of images.

• Journal of Bio-Environment Control
• /
• v.13 no.1
• /
• pp.8-15
• /
• 2004

Seedling mechanization of lettuce is known to be difficult due to the small seed size and the irregular seed shape. The purpose of seed pelleting is to make seedling mechanization possible by enlarging the seed size. After that, it can reduce seedling and thinning labours and can also save seeds. According to the results, there were significant differences on the percent germination and day to 50% final germination in accordance with the pelleting polymer. Among the pelleting polymer, gemination of seeds using polynimyl alcohol (PVA) was generally smooth, and followed by polyvinyl pyrrolidone (PVP), hydroxyethyl cellulose (HEC), methyl cellulose (MC), and wteen 80. The germination rate was also different according to the pelleting particulate matters. Generally, percent germination and speed of seed using the mixture of diatomaceous earth, talc and calcium carbonate were higher and faster than using other polleting materials, respectively. Thus, it should be suitable pelleting particulate matter for the pelleting of lettuce seeds. On the other hands germination of seeds using limestone, calcium oxide and benonite were low. The seed size of lettuce after pelleting was 33 times as large as the raw seed size. During the process of seed pelleting, netrient addition induced the decrement on the germination and the delay of germination speed. Also, there was differences in the germinability of pelleted seeds in accordance with the addition of nutrient sources. MS medium was generally lower than monosodium phosphate in inhibition of seed germination. Germination of pelleted seeds after priming was higher than the seeds without the treatment, and also showed the trend of early germination.

• Journal of KIISE:Databases
• /
• v.28 no.4
• /
• pp.732-741
• /
• 2001

In the relational database systems the join operation is one of the most time-consuming query operations. Many parallel join algorithms have been developed 개 reduce the execution time Multiple hash join algorithm using allocation tree is one of the most efficient ones. However, it may have some delay on the processing each node of allocation tree, which is occurred in tuple-probing phase by the difference between one page reading time of outer relation and the processing time of already read one. This delay problem was solved by using the concept of synchronization of page execution time with we had proposed In this paper the effects of the performance improvements in each node of the allocation tree are extended to the whole allocation tree and the performance evaluation about that is processed. In addition we propose an efficient algorithm for multiple hash joins in limited number of processor environments according to the relationship between the number of input relations in the allocation tree and the number of processors allocated to the tree. Finally. we analyze the performance by building the analytical cost model and verify the validity of it by various performance comparison with previous method.

• Journal of Sericultural and Entomological Science
• /
• v.21 no.1
• /
• pp.36-44
• /
• 1979

Those studies were examined rearing two varieties on Japanese descent and two varieties of Chinese descent by feeding polluted mulberry leaves, non-polluted ones and water-cleaned ones respectively to find effects of air-pollution on the economic characters of silkworms and analysis of contents of Sulphur and Cadmium in the mulberry leaves and silkworms as followings; 1) Japanese descent of polluted part was delayed about 2.5 days than non-polluted part, Chinese descent was delayed about 4 days or inequal and water-cleaned part was medium in the silkworm larval duration. 2) Results of maximum weight of 5th instal, cocoon layer weight and cocoon weight were decreased in due order non-polluted, water-cleaned and polluted in the factors of mulberry 3) Pupal ratio of Japanese descent was not shown statistical significance, but Chinese descent was revealed it obviously in the factors of mulberry leaves. 4) In the resistance of polluted mulberry leaves, Chinese descent was feeble obviously than Japanese and there were some difference even through among the same varieties. 5) The content of S and Cd of polluted area mulberry leaves was increased about 30% respectively than non-polluted area. 6) The fed part of non-polluted mulberry leaves was S 0.41% and Cd 0.013 ppm water-cleaned part was S 0.47% and Cd 0.024 ppm and polluted part was S 0.52% and Cd 0.042 ppm in the contents of S and Cd of silkworm larvae. 7) The contents of S and Cd didn't make visible injury in mulberry leaves but made it seriously in silkworm larvae. 8) The injury of dust on mulberry leaves was more serious than that of quality of mulberry leaves by air-pollution in the economic characters of silkworm. 9) As above results, Chinese descent should avoid contaminated area and it rearing by water-cleaned mulberry leaves can get noticable results in inevitable case on selection of parents silkworm rearingzone.

• Journal of the Korean Geotechnical Society
• /
• v.24 no.9
• /
• pp.13-21
• /
• 2008

Partitioning tracer method is a useful tool to characterize large domains of the aquifers contaminated with light nonaqueous phase liquids (LNAPLs). Sorption of the partitioning tracers to the organic matter content of soil can potentially influence the efficacy of partitioning tracer method. LNAPL-water partitioning coefficients of tracers ($K_{nw}$), measured by static method, showed linear relationship. Sorption isotherm tests were conducted to evaluate the sorption capacity of the soils packed in the columns and the results were appropriately represented by Freundlich sorption isotherm. The sorption of tracers proportionally increased with the increase of the organic matter content of the soil. Laboratory experiments were conducted in four columns each packed with soils of different organic matter contents to determine the potential interference effects of sorption to soil organic matter content and correction factors for the errors in estimation of LNAPLs by partitioning tracer method. Though there were no contaminants added, breakthrough curves from columns packed with mixture of Jumunjin standard sand and organic matter showed separation of tracers. Columns were then contaminated to residual saturation with kerosene and breakthrough curves were obtained. The results show that sorption of tracers to soil organic matter leads to an increase in the retardation factor (R) and hence, to an overestimation of the saturation of LNAPLs. A relation between the percentage of organic matter content and the corresponding percentage error in the estimation of NAPLs has been developed.

• Journal of The Korean Association For Science Education
• /
• v.31 no.8
• /
• pp.1092-1109
• /
• 2011

The purpose of this study was to analyze of the effects of instructional supervision emphasizing reflective thinking on science teaching of elementary teachers. The participants in this study were two teachers. This study was divided in former, middle, and later periods, and consisted of monitoring their own teaching, interviewing, journal writing, discussion with peer teachers and teacher training. Data included descriptions of nine science classes, nine interviews, seven journals and the journals of the researcher. Data analysis tools were the frameworks of the questions, feedback, teaching methods, elements of teaching behavior, and reflection levels. This study employed qualitative research, analysis of the frequency of data, and quoting of descriptions related to the result. The results of this study were as follows: First, teachers showed mainly technical reflection, but changed to show more practical reflection, and critical reflection in the later period of instructional supervision. Second, instructional supervision emphasizing reflective thinking on science teaching for elementary teachers meaningfully changed the question, feedback, teaching methods and teaching elements of teachers. From the results of this study, instructional supervision emphasizing reflective thinking on science teaching for elementary teachers can be considered an effective method in improving teaching elementary science, and instructional supervision used in this study made possible the higher level of reflection and appropriate teaching behavior.

• Korean Journal of Food Science and Technology
• /
• v.28 no.5
• /
• pp.904-909
• /
• 1996

To investigate effects of sugars on the retrogradation of rice flour gels, sucrose and isomaltooligosaccharide (1, 2, and 5%, w/w on the flour basis were added to 50% Dongjinbyeo rice flour gels and stored at different temperature $(20^{\circ}C,\;4^{\circ}C)$ far 1, 3 and 6 days. Changes on the degree of retrogradation (DR) of these rice flour gels were measured by α-amylase-iodine method, DSC and X-ray diffractometry. DRs of rice flour gels increased over storage and showed a rapid increase up to 3 days and then decreased thereafter. DRs of rice flour gels with sucrose or oligosaccharide also increased rapidly until 3 day storage but these values were lower than those of rice flour gels without sugar. DRs of rice flour gels with oligosaccharide were lower than those of gels with sucrose. Changes in enthalpy of rice flour gels measured by DSC showed the same tendency with those in DRs of rice flour gels by ${\alpha}-amylase-iodine$ method, but varied with sugar levels.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.9 no.2
• /
• pp.120-128
• /
• 1976

Two experiments were conducted to study the nature of protein degradation in fish muscle postmortem, first one with English sole (Paraphyrus vetulus) followed by another with rockfish (Sebastodes spp.). In the first one, proteolysis was measured by the increase of amino-N in gutted fish during storage in ice and in the homogenates prepared from fish of different ice storage during $20^{\circ}C-incubation$. In order to test the possible involvement of fish muscle a cathepsin, a portion of each homogenate sample was exposed to 0.5 Mrad of gamma radiation to destroy viable microorganisms prior to the incubation. Proteolysis was not detected until viable count reached a level above $10^7$ cells per gm fish flesh, corresponding to 31 days of ice storage. Even if fish flesh were mechanically disrupted by means of homogenization and subsequently incubated at $20^{\circ}C$, proteloysis attributable to muscle cathepsin was not detected. In the second with rockfish muscle aseptically prepared from freshly killed fish, the samples were inoculated with a proteolytic strain of fish spoilage Pseudomonad or irradiated at 0, 0.5 and 3.0 Mrad. The four samle groups were stored at $0-2^{\circ}C$ to compare the spoilage pattern of sterile and non-sterile muscle. In sterile muscle both total-N (extracted in 0.5M KCl) and amino-N $(soluble\;in\;70\%\;ethanol)$ declined slightly while the inoculated muscle showing increase in parallel with the increase of number of inoculated bacterium. The results indicate that proteolysis is a part of normal fish spoilage and the onset of proteolysis is delayed until viable count reaches its maximum level. Contribution of fish muscle cathepsin to protein degradation in white flesh fish muscle post-mortem is nil.