• Title/Summary/Keyword: 질병회복

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Comparative Effectiveness of Adjunctive Aripiprazole versus Bupropion Uses to Selective Serotonin Reuptake Inhibitor on the Specific Symptom of Depression : A post-hoc, Multi-Center, Open-Label, Randomized Study (세로토닌 재흡수 억제제에 대한 아리피프라졸 및 부프로피온 부가요법의 우울증 세부증상에 대한 효과 비교 : 다기관, 개방표지, 무작위 연구)

  • Lee, Ga-Won;Lee, Kwang-Hun;Park, Young-Woo;Lee, Jong-hun;Koo, Bon-Hoon;Lee, Seung-Jae;Sung, Hyung-Mo;Cheon, Eun-Jin
    • Anxiety and mood
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    • v.13 no.2
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    • pp.66-73
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    • 2017
  • Objective : The purpose of this study was to examine the effects of adjunctive aripiprazole versus bupropion on specific symptoms of depression. Methods : Data were from 6-week, randomized, prospective, open-label multi-center study in 103 patients with major depressive disorders. Participants were randomized to receive aripiprazole (2.5-10 mg/day) or bupropion (150-300 mg/day) for 6 weeks. Change in four subscales of the 17-item Hamilton Depression Rating Scale (HAM-D17) that capture core depression symptoms was determined, and change in individual HAM-D17 items was also assessed. Changes in three composite subscales-anxiety, insomnia, and drive were also examined. Results : Within-group change in the four core subscales was large [effect size (ES)=1.30-1.47] and it was similar to that in the HAM-D17 total score. Differences between aripiprazole and bupropion were significant for each of the four core subscales and the HAM-D17 total score favored aripiprazole (p<0.001). On three composite scales, both treatments caused substantial changes in anxiety (within-group ES=1.10 (aripiprazole) vs. 1.00 (bupropion)], insomnia (ES=0.75 vs 0.50), and drive (ES=1.17 vs 1.15). Conclusion : This results suggested that both aripiprazole and bupropion adjunctive therapies with selective serotonin reuptake inhibitors resulted in significant and clinically meaningful changes in core symptom subscales for depression.

A Clinical Study of 52 Patients with Myasthenia Gravis Syndrome (중증 근무력증 52례에 대한 임상적 고찰)

  • Park, Gun-Ju;Hah, Jung-Sang;Lee, Jun;Do, Hyun-Cheol;Park, Seung-Kweun;Suh, Sang-Dug;Kee, Byung-Soo;Kim, Jin-Kook
    • Journal of Yeungnam Medical Science
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    • v.13 no.1
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    • pp.86-96
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    • 1996
  • The authors experienced 52 patients with myasthenia gravis who were diagnosed at the Department of Neurology, Yeungnarn University Hospital from August 1985 to January 1996. The following results were obtained through diagnostic evaluation and treatment. 1. The ratio of male to female was 1:1.7 and the most prevalent age group was second decade. 2. The most common initial presentation symptom was ocular(71.2%) and the peak incidence group was stage I (69.3%) according to the modified Osserman's classification. 3. In 16 patients(30.8%), it took more than a year to diagnose due to symptoms which were relapsed and remitting. 4. Of 52 patients, 2 cases were associated with thyroid disease(3.8%) and 2 with insulin-dependent diabetes mellitus(3.8%). 5. All of those who received anticholinesterase and corticosteroid therapy were improved with the exception of 5 cases which were improved after thymectomy and/or plasmapheresis. 6. Spontaneous remission was occured in 2 cases(3.8%) of ocular myasthenia gravis. And 1 case of group II. was cured through thymectomy and long-term corticosteroid therapy.

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The Study on New Poverty and Change of Poverty Policy in Korea (한국의 신빈곤현상과 탈빈곤정책에 관한 연구: 근로빈곤층(the working poor)의 실태를 중심으로)

  • Kim, Young-Lan
    • Korean Journal of Social Welfare
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    • v.57 no.2
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    • pp.41-70
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    • 2005
  • The object of the study is to examine the change of social-economic structure and poverty-shape to escape poverty. In Korea, the working poor have been increased by flexibility and division of labor market since the economic crisis in 1997, and are faced with hard conditions due to the vulnerable welfare system. Especially the workers who engage in irregular jobs were increased by restructure of labor market. Besides they are in unstable employment terms such as low payment, low-skill and exclusion from welfare-benefit. Many small independent businessmen are also in danger of poverty for enterprises trend to move abroad by globalization. Poverty policy in our country was focused on the absolute poor class that has relation with old age, unemployment, disable, disease etc, so they were the object of welfare policy. The poverties, however, are increasing rapidly after the economic crisis, and they work so hard but are still poor, that is, participation in labor market doesn't become an element to escape poverty. Thus the emergence of new poverties whose core consists of the working poor becomes to need new poverty policy. The study is to survey change of their economic conditions, their welfare conditions, their experiences and responses of social dangers after the economic crisis, then to explore the policy to escape poverty. As the result of the study, it shows that the working poor experienced many kinds of social dangers like unemployment, decrease of income etc. In their welfare conditions as their responses to the social dangers, the benefit of social insurance, enterprise welfare like legal retirement pay and paid leave and private welfare such as private pension and insurance are low. The working poor are faced with social dangers, moreover, they don't have skill or education for adapting themselves to information society. The study says that it needs variable policies for the working poor to escape poverty, and suggests payment & tax policies as stable income policy, occupational discipline and skill-education for promoting the quality of employment, moreover, social insurance as expansion of social welfare policy and housing & education policies whose objects are the working poor.

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A Study of Trade-Off Relationship Between Income Maintenance Programs and Social Services (소득보장과 사회서비스의 교환관계(trade-off) 연구)

  • Moon, Jin Young;Kim, Yun Young
    • Korean Journal of Social Welfare
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    • v.67 no.4
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    • pp.203-226
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    • 2015
  • It is widely accepted that one of the main challenges of the 21st century welfare state is how to harmonize 'Old Welfare, Old Risks' which mostly consists of income maintenance programs with 'New Welfare, New Risks' which actively advances social services. It is in this regard that this paper attempts to define the relationship between the income maintenance programs and social services. For this purpose, it analyses social expenditure of 18 OECD countries during 1980-2006, and subsequently attests, if there is a trade-off relationship between the two, using correlation and Granger panel analysis. It duly concludes that the trade-off relationship between the two is not valid in that the two are better understood as a complementary relationship, not substitute relationship.

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The Developmental Program of Emergency Medical System in Correctional Facilities (교정시설 내 응급의료체계 발전방안)

  • Kim, Su-Il
    • Journal of forensic and investigative science
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    • v.3 no.1
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    • pp.60-73
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    • 2008
  • The purpose of Emergency Medical System(EMS) is what a patient returns to society with recovering mental tone in the shortest time as giving prompt and proper medical treatment to patient in emergency situation, and the Correctional Administration(CA) is purposed for the convict to return and settle down to society after release from prison in success as executing schooling, enlightenment activity, vocational training to convict who was quarantined from the society for the term of imprisonment. The EMS and CA will coincide each other which is reverting people to society in safety. This study aims to suggest the developmental program of EMS in correctional facilities through the cause of emergency situation, system, human resources, establishment, medical equipments, state of budget and the point issue for safety of victim who has many chances that is exposed to physical damage and disease because of particularity of lower culture in correctional facilities and the staff who works there. First, in the view of the correctional facility security system, a proper number of the emergency rescuers should be employed. Second, the effective transportation system along with some emergency medical equipment needs to be established. Third, the correctional officers and the prisoners should be learned the first-aid training which is realistic, practical and systematic. Fourth, the cooperative system should be established such as 1339 emergency medical information center in society. Fifth, the Ministry of Health and Welfare must increase EMS budget for correctional facilities.

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Rapid Detection of Lactobacillus Genus Inhabiting in Vagina of 20's Healthy Women Using Multiplex PCR (Multiplex PCR 분석을 통한 건강한 20대 여성의 질 내에 서식하는 Lactobacillus 속 유산균의 신속한 검출)

  • Oh, Cho-Rong;Cho, Hong-Bum
    • Korean Journal of Microbiology
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    • v.48 no.4
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    • pp.309-313
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    • 2012
  • The purpose of this study is to simultaneously detect and identify specific genus of Lactobacillus distributed in vagina of healthy women in their twenties by using multiplex primer. Vaginal fluid samples were taken from 166 women who were healthy and did not have vaginosis symptoms caused by bacterial infection. Six species of lactic acid bacteria belong to Lactobacillus genus that are known to inhabit in healthy vagina were selected to make a species-specific multiplex primer. Multiplex primer I was specified to selectively detect L. iners, L. crispatus, L. gasseri and multiplex primer II was specified to selectively detect L. acidophilus, L. jensenii, L. fermentum. L. crispatus (77%) was most frequently detected, and L. acidophilus (57%) and L. jensenii (57%) were relatively higher than others. Although the proportion of L. iners (59%) was a little higher than those of L. acidophilus and L. jensenii, this should be further validated in healthy women's vagina to be sure since they often appear in women having bacterial vaginosis and/or during the antibiotic therapy. Conclusively, the multiplex PCR technique using the species-specific primer could a useful tool to predict variation of vaginal health condition and process of recovery from vaginal disease.

Histopathological studies on the macrophage behavior in lymphomyeloid tissues of tilapia, Oreochromis niloticus (나일틸라피아의 임파조혈조직내 대식세포(大食細胞) 분포변화(分布變化)에 관한 병리조직학적(病理組織學的) 연구(硏究))

  • Lee, Nam-Sil;Kim, Jee-Young;Jeong, Hyun-Do;Huh, Min-Do
    • Journal of fish pathology
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    • v.8 no.2
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    • pp.135-148
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    • 1995
  • To elucidate the distributional pattern of macrophages within lymphomyeloid tissues according to the disease process, tilapias, teleostean fish, were intraperitoneally injected with live Edwardsiellatarda and its extracellular product(ECP) respectively. And then histopathological examination for the spleen and gead kidney were carried out for the individuals which had not any clinical signs. In the group injected with live E. tarda, macrophages were densely organized into MMC-like structures with showing some degree of recovery in histological arrangement. At the 2nd week, overall structures of the lymphomyeloid tissues became normal, accompanying the disappearance of most of macrophage groups. Also in case of ECP injection, quite similar findings were observed. Moreover, macrophage collections and hypertrophied ellipsoids were recognized at 1hour after the injection of ECP in head kidney and spleen, respectively. These results suggested that characteristic behaviors of macrophages in lymphomyeloid tissues would be used as important morphological criteria for early diagnosis of edwarsiellosis or possibly of other infectious diseases.

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Assessment of Functional Food Consumption Among the Working Women in Korea (한국 직장 여성의 건강식품 섭취 실태에 관한 연구)

  • Chang, Min-Ki;Kim, Yang-Ha
    • Journal of Nutrition and Health
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    • v.41 no.8
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    • pp.832-838
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    • 2008
  • The aim of this study was to identify the status of health functional food consumption of working women. The 558 subjects of the study were aged between 10-60 years, and had previous experiences of consuming health functional foods. The majority of the subjects lived in Seoul, and some lived in the Gyeonggi Province. The most prevalent goals that the subjects hoped to achieve by consuming health functional foods were improvement of physical health status and reduction of exhaustion. Other goals included supplement of nutrition, and prevention or treatment of diseases. Those who were older or who possessed a high BMI spent more expenses on health functional foods, and showed a higher intake frequency as well as longer periods of consumption. Subjects placed in the older group showed a lower level of knowledge related to functional foods, which turned out to be statistically significant. Most of the respondents answered that their knowledge related to functional foods was picked up from listening to others. In conclusion, we were able to observe that groups with elder working women and high BMI show higher consumption and expense rates of health functional foods, as well as longer periods of consumption. However, they show a minimum level of knowledge related to functional foods. According to our results, these subjects should seek practical help in order to select functional foods that will aid their health, and learn the proper method of consumption. In order to reduce inaccurate consumption of health functional foods, it is imperative that more in-depth study is carried out in this field.

Adult-role Burdens and Socio-emotional Development of Children in Poverty (빈곤과 아동의 사회정서적 발달 간의 관계 : 성인역 부담의 역할을 중심으로)

  • Park, Hyun-Sun;Chung, Ick-Joong;Ku, In-Hoe
    • Korean Journal of Social Welfare
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    • v.58 no.2
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    • pp.303-330
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    • 2006
  • The purpose of this study was to investigate the relationships among poverty, family structure and functioning, burdens of adult roles and socio-emotional problems. It was especially focused on the relationship between the burden of adult roles and socioemotional problems among children in poverty. The Structural Equation model was employed for analyses. The Theoretical model was established based on previous researches related to poverty and adult roles (for example, parentification and parentified children). Data came from the first wave of 'Seoul Panel Study of Children; SPSC' and subjects consisted of 1,807 4th grade elementary school students and their parents who were located at K-Gu in Seoul. The survey was carried out from October 25th to November 20th in 2005. The Results of the Structural Equation model were congruent with the theoretical expectations. To find a more appropriate model, three kinds of structural models were hypothesized and analysed. In the most appropriate model which had a good model fit, poverty and family structure impacted on socio-emotional problems directly and indirectly. The relationship between poverty and socio-emotional problems was mediated by family functioning and burdens of adult roles. The same mediation process existed between family structure and socio-emotional problems also. In brief, children in poverty or those who have a single parent are more likely to have impaired family functioning, which is likely to cause higher burdens of adult roles. In turn, those who have higher burdens of adult roles are more likely to have socioemotional problems. In conclusion, various theoretical and practical implications for social work practice focusing on the burdens of adult roles or caretaker roles among children in poverty were discussed.

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A Theoretical Review on the Planting and Management of Coastal Forests in Korea (우리나라 해안림조성과 관리의 이론적 고찰)

  • Kim, Yong-Shik;Kim, Do-Gyun
    • Korean Journal of Plant Resources
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    • v.30 no.1
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    • pp.110-123
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    • 2017
  • The authors reviewed the history of creation and management, purposes, extents, methods of creation, planting species and mediums, structure of vegetation layers and legal management, etc. of coastal forests of Korea. Since the Goryeo dynasty, the inhabitants in the coastal regions has long been aware the safety from natural disasters and the local governments manages for the defence and natural disasters, and collaboration among GO and NGOs, as well as enterprises are participating to the conservation of coastal forests in Korea. The purposes of creation and management of coastal forests in historical aspects are prevention of disasters, safety by the Fengsui, military uses, and timber productions, but partly as the places for religious beliefs, safety from diseases and fires, increasing of forest products and fishes, as well as tourists, improving of amenity and landscapes and recreation, inherits of traditional culture, habitats for wildlife, and ecological corridors, etc. The inhabitant in the coastal region who experienced frequent natural disasters has strong supports for the conservation of coastal forest and as a natural resources to inherits to the coming generations as the coastal forests has high values of academic researches on human society, culture, ecology and recreational uses, etc. The extensive overall researches on the creation and managements of coastal forests, as well as cultural tradition in the coastal forests of Korean peninsula are critically essential.