• Korean Journal of Applied Biomechanics
• /
• v.24 no.3
• /
• pp.287-293
• /
• 2014

The purpose of this study was to investigate the effects of Hoehn-Yahr scale on the activation of lower-extremity muscles during walking. Electromyography (EMG) analysis was carried out on 36 patients with Parkinson's disease in the off phase of the medication cycle. We recorded EMG signals of the tibialis anterior (TA), medial gastrocnemius (MG), lateral gastrocnemius (LG), soleus (SOL), rectus femoris (RF), vastus lateralis (VL), semitendinosus (ST) and biceps femoris (BF) using Noraxon 16 channels EMG system during walking at preferred speed. Rectified EMG signals were normalized to reference voluntary contractions (RVC) over a gait cycle at the preferred speed, allowing for an assessment of how the activity was distributed over the gait cycle. Compared to the H & Y Scale 1, H & Y Scale 3 exhibited greater activation of the vastus lateralis during mid-stance and greater activation of the medial gastrocnemius during terminal swing. Compared to the H & Y Scale 1, H & Y Scale 2 and 3 exhibited less activation of the tibialis anterior during initial swing. We conclude that the more Hoen & Yahr Scale increase, the more abnormal lower-extremity muscles activation.

• Korean Journal of Veterinary Research
• /
• v.34 no.2
• /
• pp.381-386
• /
• 1994

Evidence is presented for the isolation and characterization of Anaplasma avis in both indigenous (Korean) and exotic goats imported from Australia. These studies were carried out in response to epidemic scenario whereby farmers reported noticing what was described as a mysterious disease characterized by anemia, anorexia, general malaise and a significant morbidity and mortality rate in both types of goat breeds. The syndrome consistent with caprine anaplasmosis was associated with an intraerythrocytic agent occuring in single initial bodies characteristically surrounded by a single-layered membrane whereas the marginal body was typically surrounded by a double-layered membrane. The identity of the etiologic agent was confirmed as Anaplasma avis by light and ultrastructural microscopy.

• Journal of Veterinary Clinics
• /
• v.19 no.1
• /
• pp.14-18
• /
• 2002

An epidemiological study was performed to evaluate the state of fish diseases between aquaculture fishes in the area of southern Kyeongnam, especially Tongyeong-si, Geoje-si, and Goseong-gun. Examination for a total of 91 cases was carried out for a variety of fishes, including Japanese flounder(Paralichthys olivaceus), rock fish (Sebastes schlegeli), sea bass (Lateolabrax japonicus), sea breams(Pagrus major), and red drum (Sciaenops ocellatus) from November, 1999 to October, 2001. The investigation resulted in exploring 155 infectious diseases, including 62 Vibriosis, 16 Edwasiella infection, 11 Streptococcosis, 7 Pseudotuberculosis, 15 Scuticociliatida infection, 20 Gill flukes, and 9 Trichodiniasis. When the infections were classified according to fish species, Japanese flounder was infected by 30 Vibrio spp., 16 Edwardsiella tarda, 6 Streptococcus spp., 12 Scuticociliatida infection. In case of sea bass, 10 Vibrio spp. was able to isolate out of 10 outbreaks, on the other hand, rock fish was dominantly infected by gill flukes since it was observed 12 out of a total of 20 cases. With reference to seasonal fluctuation, Vibrio spp. infection was continually observed through all seasons but Edwardsiella septicaemia, Streptococcosis and Pseudotuberculosis was mainly isolated in summer and autumn when the water temperature was raised high. Scuticociliatida infection was frequently occurred from late autumn to early spring but gill flukes were watched all the year regardless of temperature. As regards, multiple infection, 47 out of 91 cases was Identified to have involved in more than 2 pathogens, especially Vibrio spp. was highly mixed with other pathogens since 42 out of 47 cases was mixed with Vibrio spp.

• Journal of the Korean Society of Radiology
• /
• v.13 no.4
• /
• pp.597-603
• /
• 2019

We obtained a Dicom file using a CT (Computed Tomography), a diagnostic test device used in clinical practice. Dicom files and 3D programs, and finger printers with 3D printers. Because the finger brace is intended for the human body, the accuracy of the shape is very important. 3D Print has the advantage of high precision, variety of materials, and short output time. In clinic, aluminum protector or medical device manufacturer's finger protector is limited. By creating a finger brace with a 3D printer, we expect to be able to apply a precise form of a custom finger brace to the patient that can be used to treat a patient's finger trauma, illness, or deformity.

• Korean journal of aerospace and environmental medicine
• /
• v.29 no.3
• /
• pp.96-100
• /
• 2019

The present study analyzed all of exotic malaria (EM) cases reported in the Republic of Korea (Korea) and Japan from 2015 to 2017 to assess the trends of incidence overtime to review the risk factors for travelers visiting malaria-endemic countries. We investigated 162 cases of EM in Korea with a cumulative incidence rate (CIR) of 0.105 per 100,000 populations nationwide and the CIR of the oversea travelers was 0.238 per 100,000 travelers, respectively. During the same period in Japan, 152 cases of EM in nationwide with a CIR of 0.041 and in the oversea travelers with a CIR of 0.297 were observed. When compared, the CIR of EM in nationwide was much higher than that in Japan (P<0.01), but a CIR of imported by travelers in Korea was lower than that in Japan (P<0.01).

• Pediatric Infection and Vaccine
• /
• v.30 no.1
• /
• pp.1-11
• /
• 2023

Respiratory syncytial virus (RSV) is a pathogen with a high burden of disease and social cost among infants worldwide, but the development of a vaccine has been delayed. The recent understanding of the pathogenesis of RSV, progress in reverse genetics, and successful implementation of other maternal immunizations have prompted the recent rapid development of monoclonal antibodies (mAbs) and vaccines for RSV prevention. Phase 3 clinical trials for two next-generation mAbs (nirsevimab and clesrovimab) and two maternal RSV pre-F vaccines are currently underway or have been recently completed. Soon, we might be able to protect young infants through long-acting mAbs and/or maternal immunization. Additionally, the development of live-attenuated vaccine candidates that are capable of avoiding enhanced RSV disease is ongoing. We need to gain familiarity with these newly developed strategies and collect epidemiological data on domestic RSV to adequately prepare for a new era of RSV prevention.

• Korean Journal of Occupational Health Nursing
• /
• v.32 no.4
• /
• pp.131-140
• /
• 2023

Purpose: We reviewed the cases of occupational diseases that occurred in healthcare workers from 2010 to 2019 and the cases of epidemiological investigations conducted by the Occupational Safety and Health Research Institute for them. Methods: In this study, gender, age, working period, occupational characteristics, and disease characteristics by occupation, which are general characteristics of healthcare workers approved for occupational diseases. In addition, 32 cases of epidemiological investigation of healthcare workers conducted by the Institute for Occupational Safety and Health for the past 10 years (2010~2019) were analyzed. Results: The gender, age, working period, occupational characteristics, and disease characteristics by occupation of medical workers recognized as occupational diseases were all statistically significant (p<.001). In the epidemiological investigation, ionizing radiation( 50.0%) and stress (33.3%) were recognized as disease-related factors, and even in cases of disapproval, ionizing radiation (60.0%) and shift work (25.5%) were designated as related factors. And it was statistically significant (p=.008). Conclusion: The current study identified the types of diseases, various causes, and general characteristics and occupational characteristics that occur frequently in healthcare workers. Therefore, if this study is used as basic information to set the priority and direction of disease prevention project for healthcare workers, it is judged that it will be helpful in preventing industrial accidents.

• Pediatric Infection and Vaccine
• /
• v.21 no.3
• /
• pp.174-180
• /
• 2014

Purpose: This study was performed to assess the clinical and epidemiological changes after the introduction of the rotavirus vaccine in Korea, as well as to determine the efficacy of the rotavirus vaccine among hospitalized rotaviral gastroenteritis patients over the past two years. Methods: We analyzed yearly and seasonal patterns of 1,165 inpatients who were hospitalized for rotaviral gastroenteritis under the age of 5 years between 2006 and 2013. We also conducted a survey among 460 gastroenteritis patients who were hospitalized between 2012 and 2013 regarding the rotavirus vaccination and the symptoms of gastroenteritis. Among those individuals surveyed, clinical indices were analyzed for 124 patients who were tested positive for the rotavirus antigen. Results: The incidence of Rotaviral gastroenteritis have decreased significantly by year 2010. After the introduction and widespread dissemination of the rotavirus vaccine, the onset of the disease and the seasonal peak have been delayed. Overall, the vaccinated group showed a lower rate of positivity than the unvaccinated group. Among the hospitalized rotaviral gastroenteritis patients, the vaccinated group had a shorter hospitalization period, less severe clinical symptoms of gastroenteritis, and better laboratory test results. Conclusions: After introduction of the rotavirus vaccine in Korea, there were two main trends observed: 1) the overall level of disease incidence was reduced; 2) the severity of rotaviral gastroenteritis cases also decreased. Based on this data, more children should receive vaccination in order to prevent the rotavirus infection and decrease the severity of rotaviral gastroenteritis.

• Journal of Food Hygiene and Safety
• /
• v.14 no.4
• /
• pp.319-326
• /
• 1999

Recently, it is continuously rising to concern about the health risk being induced by microorganisms in food such as Escherichia coli O157:H7 and Listeria monocytogenes. Various organizations and regulatory agencies including U.S.FPA, U.S.DA and FAO/WHO are preparing the methodology building to apply microbial quantitative risk assessment to risk-based food safety program. Microbial risks are primarily the result of single exposure and its health impacts are immediate and serious. Therefore, the methodology of risk assessment differs from that of chemical risk assessment. Microbial quantitative risk assessment consists of tow steps; hazard identification, exposure assessment, dose-response assessment and risk characterization. Hazard identification is accomplished by observing and defining the types of adverse health effects in humans associated with exposure to foodborne agents. Epidemiological evidence which links the various disease with the particular exposure route is an important component of this identification. Exposure assessment includes the quantification of microbial exposure regarding the dynamics of microbial growth in food processing, transport, packaging and specific time-temperature conditions at various points from animal production to consumption. Dose-response assessment is the process characterizing dose-response correlation between microbial exposure and disease incidence. Unlike chemical carcinogens, the dose-response assessment for microbial pathogens has not focused on animal models for extrapolation to humans. Risk characterization links the exposure assessment and dose-response assessment and involve uncertainty analysis. The methodology of microbial dose-response assessment is classified as nonthreshold and thresh-old approach. The nonthreshold model have assumption that one organism is capable of producing an infection if it arrives at an appropriate site and organism have independence. Recently, the Exponential, Beta-poission, Gompertz, and Gamma-weibull models are using as nonthreshold model. The Log-normal and Log-logistic models are using as threshold model. The threshold has the assumption that a toxicant is produce by interaction of organisms. In this study, it was reviewed detailed process including risk value using model parameter and microbial exposure dose. Also this study suggested model application methodology in field of exposure assessment using assumed food microbial data(NaCl, water activity, temperature, pH, etc.) and the commercially used Food MicroModel. We recognized that human volunteer data to the healthy man are preferred rather than epidemiological data fur obtaining exact dose-response data. But, the foreign agencies are studying the characterization of correlation between human and animal. For the comparison of differences to the population sensitivity: it must be executed domestic study such as the establishment of dose-response data to the Korean volunteer by each microbial and microbial exposure assessment in food.

• Childhood Kidney Diseases
• /
• v.13 no.1
• /
• pp.63-74
• /
• 2009

Purpose : The current nationally representative data on inpatient care are important to make the of the national public health policy because distributions and the prevalence of diseases among children and adolescents represent the socioeconomic status of the society. The prevalence of chronic disease is increasing now in Korea as the socioeconomic condition is improving. We analyzed a part of genitourinary tract disease of the cross-sectional hospital discharge survey data in Korea collected recently to delineate the trend of genitourinary tract diseases. Methods : Korean nationwide hospital discharge survey for pediatric inpatients in the period from 2004 to 2006 was analyzed. Diagnoses in the data were coded using ICD-10 classification. Totally 826,896 cases were collected from the 85 training hospitals. Selected data of genitourinary tract diseases (belonging to N00-N99 by ICD-10) among 826,896 cases of final inpatients data were analyzed for this study. Results : Among total patients of 826,896, diseases of the genitourinary system accounted for 4.1%. and four diagnostic categories accounted for 92.8%. These were other diseases of the urinary system (N30-39), 45.8%, disease of male genital organs (N40-51),19.1%, glomerular diseases (N00-08), 17.3%, renal tubulo-interstitial diseases (N10-16), 10.6%, respectively. Conclusion : Genitourinary tract disease in pediatric inpatient shows decreasing tendency but the prevalence of chronic diseases is increasing in Korea as the socioeconomic condition is improving. For further comprehensive analysis, regular and organized nationwide survey should be performed. Development of a new data collecting system will improve the performance of such nationwide survey.