• Radiation Oncology Journal
• /
• v.11 no.1
• /
• pp.119-126
• /
• 1993

From 1988 to 1991, nineteen patients with unresectable localized pancreatic carcinoma were treated with radiotherapy and/or hyperthermia or in combination with chemotherapy. Radiation dose of 4500-5000 cGy with or without additional 500-1000 cGy was administered over 5 to 6 weeks to the pancreatic tumor area using 10 MV linear accelerator. Five of 19 patients were given chemotherapy, either neoadjuvant or maintenance setting with FAM regimen (5-FU, adriamycin and mitomycin C), which was repeated every 4 weeks for one year or until progression. Symptomatic palliation was achieved in 17 among 19 patients ($89{\%}$) and objective response (complete or partial response in CT finding) was achieved in 5 among 11 patients ($45{\%}$). The median survival time was 9 months and one-year survival rate, $32{\%}$. Local-regional failure was documented in 10 among 13 patients ($77{\%}$) and distant failures were found in the liver (3 patients) and carcinomatosis (2 patients). Prognostic significance of various factors such as age, sex, performance status, tumor location, stage, etc. were assessed. Any factors did not have the prognostic significance in univariate analysis. Treatment was well tolerated in most of the patients with only mild to moderate toxicity.

• Radiation Oncology Journal
• /
• v.11 no.2
• /
• pp.193-203
• /
• 1993

In understanding radiosensitivity a new concept of inherent radiosensitivity based on individuality and heterogeneity within a population has recently been explored. There has been some discussion of possible mechanism underlying differences in radiosensitivity between cells. Ataxia telangiectasia (AT), a rare autosomal recessive genetic disorder, is characterized by hypersensitivity to ionizing radiation and other DNA damaging agents at the cellular level. There have been a lot of efforts to describe the cause of this hypersensitivity to radiation. At the cellular level, chromosome repair kinetics study would be an appropriate approach. The purpose of this study was to better understand radiosensitivity En an approach to investigate kinetics of induction and repair of $G_2$ chromatic bleaks using normal, AT heterozygous (ATH), and AT homozygous lymphoblastoid cell lines. In an attempt to estimate initial damage, $9-{\beta}-D-arabinosyl-2-fluoroadenine,$ an inhibitor of DNA synthesis and repair, was used in this study. It was found from this study that radiation induces higher chromatid breaks in AT than in normal and ATH cells. There was no significant differences of initial chromatid breaks between normal and ATH cells. Repair kinetics was the same for all. So the higher level of breaks in AT $G_2$ cells is thought to be a reflection of the increased initial damage. The amount of initial damage correlated well with survival fraction at 2 Gy of cell survival curve following radiation. Therefore, the difference of radiosensitivity in terms of $G_2$ chromosomal sensitivity is thought to result from the difference of initial damage.

• Journal of Engineering Education Research
• /
• v.14 no.4
• /
• pp.39-47
• /
• 2011

This paper deals with nanoethics as a sort of extension of engineering ethics utilizing various books, articles, and reports concerning historical, social, and ethical aspects of nanotechnology. After a brief examination on the place and development process of nanotechnology, ethical issues on nanotechnology are analysed including safety problem, impact on environment, violating privacy, social inequity, military use, and human enhancement. The basic principles on nanoethics are proposed such as promotion of public understanding, construction of participatory governance, contribution to sustainable development, commitment to precautionary principle, and compliance with research integrity. Lastly, integrated method in nanoethics education is illustrated putting lecture model, investigation model and discussion model together. This paper can provide the contents available for nanoethics education, and make a basis for the sound development of nanotechnology.

• Convergence Security Journal
• /
• v.17 no.1
• /
• pp.81-88
• /
• 2017

The purpose of this study is to analyze any hinderance factors for successful attending system of Korean National Assembly and to provide improvement plans of legal systems to ensure security of National Assembly. First, the conceptualization and functions of Korean National Assembly attending system were discussed and related regulations and laws were also examined. Second, hinderance factors, such as sharp increase in 1) illegal behaviors, 2) bring in prohibited items, and 3) possibility of National Assembly terror, for successful attending systems were analysed. Third, improvements of legal system for security enhancement of National Assembly Attending System were discussed: 1) new legislation for providing National Assembly's security officers with special judicial police power is needed to deal with criminal behaviors and to protect human rights, and 2) legal reforms are required to provide right to command to National Assembly's Security Planning Office rather than National Assembly security office under Seoul Metropolitan Police Agency in order to unify commanding system.

• Journal of Korean Society of Archives and Records Management
• /
• v.18 no.2
• /
• pp.85-108
• /
• 2018

Oral history research in Korea began with the effort to find out the truth behind the hidden historical issues that occurred during the mid-1980s. Since then, attempts to record the major issues through contemporary Korean history orally has increased. From the late 2000s, the focus shifted to local and smaller village units. In Busan, from 2009 to 2016, 33 oral history projects from 10 government agencies were conducted. This research was carried out to investigate what kind of oral records has been produced in Busan from the said period and how they are managed. With these findings, possible solutions to preserve and utilize the oral records as the locality archives are suggested.

• Korean Educational Research Journal
• /
• v.40 no.3
• /
• pp.17-38
• /
• 2019

Deleuze and Guattari revive the educational meaning of training. For them, "a violent training" always penetrates unconsciousness and consciousness. For example, we can float on water only by swimming. There is a complex historical exploration on the subject of training. Socrates distinguishes the training of spirit from that of the body, so he secures the independence of educational language. This heritage continues to us until today. However, Foucault argues that, since the modern era, humans have accepted an active obedience by "disciplinary training". Nowadays, the term "skill discipline" is also reduced to business language, and we should overcome this situation. Deleuze and Guattari suggest a "becoming-other" argument predicated on "pre-conscious singularities" on this point. The training of spirit evolves in relation to a body and other circumstance for them. Therefore, the traditional hierarchy between spirit and body is erased in their argument. Ironically, this argument displays "educational effectiveness" to success Socrates's heritage subverting to the modern thinking of it. In conclusion, we can now rethink the educational value of training based on this effectiveness. Kyudo training is an excellent example of education through body and spirit.

• The Journal of Korean Academic Society of Nursing Education
• /
• v.20 no.4
• /
• pp.639-649
• /
• 2014

Purpose: This study evaluates the feasibility of Korean Advance Directives (K-AD) developed earlier. Method: From January 1 to February 28, 2013, data were collected from 330 adults through a self-reported questionnaire established by the authors based on literature review and expert consultation. The feasibility of K-AD was multi-dimensionally evaluated through four criteria: cognitive, psychological, document making and socially expecting aspects. Data were analyzed using t tests, one-way ANOVA, and Scheffe post hoc tests via the SAS 9.1.3 program. Results: The feasibility of K-AD differed significantly by gender (p=.003), educational level (p<.001), religion (p=.002), and self-reported health status (p=.039). Differences in the level of easiness with K-AD by gender (p=.008) and education (p=.047) were significant. Perceived simplicity of AD differed significantly by religion (p=.005), and the necessity of AD differed significantly by gender (p=.025) and religion (p=.005). Conclusion: K-AD are sufficiently feasible to be tentatively utilized in practice. This is the first study to explore the feasibility of K-AD on the basis of multiple aspects. However, further studies involving diverse populations and methodologies to validate the usefulness of K-AD are warranted.

• Nuclear industry
• /
• v.37 no.8
• /
• pp.24-33
• /
• 2017

영화 '판도라'에 투입된 정도의 돈은 막대한 예산을 갖고 있는 국제 그린피스나 매년 전 세계 TV 광고에만 수천만 달러를 쏟아 붓는 천연가스 이익단체들의 예산에 비하면 조족지혈의 수준이다. 국제 그린피스의 연간 예산이 대략 4억 달러, EDF가 1억4천만 달러, 천연자원보호협회(NRDC)와 시에라클럽이 1억 달러가 넘고, 이들 단체가 예금이나 주식에 투자한 돈만 해도 수억 달러나 된다. 시에라클럽이나 NRDC, EDF는 블로그에 원자력을 화석연료로 대체하는 것에 반대하는 글을 올리면서 다른 한편으로는 뉴욕에 있는 Indian Point, 캘리포니아에 있는 Diablo Canyon, 그리고 오하이오에 있는 여러 원전들을 천연가스로 대체해야 한다고 주장하는 기만책을 쓰고 있다. 자연과의 조화를 위해서라도 신재생에너지를 사용해야 한다는 그들 주장의 베일 뒤에는 더 큰 어두운 그림자가 깔려 있다. 가난한 나라는 계속해서 가난하도록 해야 '과잉 인구'와 '과소비'를 막을 수 있다는 반인륜적인 멜더스(Malthusian) 이론과 그들이 주장하는 반핵의 오랜 역사는 서로 그 맥을 같이하고 있기 때문이다. 탈원전이 추진되면 전기요금도 올라가고 실업률도 증가한다는 사실, 그리고 환경 오염도 더 심해지고 그로 인해 조기 사망자 수도 증가한다는 사실을 보여주는 데 반드시 어려운 경제 모델이나 환경 모델이 필요한 것은 아니다. 원자력을 천연가스로 대체하면 그에 따른 비용 상승이 연간 최소 110억 달러나 된다. 물론 신재생에너지로 대체하게 되면 그 상승폭은 더욱 커지게 된다. 그리고 한 경제 분석 전문기관의 연구에 따르면 전기요금이 상승되면 한국의 경제는 저성장에서 벗어나지 못하게 된다. 결국 지금 우리에게 가장 필요한 것은 원자력 휴머니즘, 즉 원자력 에너지가 갖고 있는 훌륭한 도덕적인 목적을 다시 한 번 상기하면서, 우리 인류가 가지고 있는 가장 중요한 환경 기술을 반인륜적인 집단으로부터 구해내기 위한 풀뿌리 시민사회의 가열찬 노력이라고 할 수 있다. 우리와 같은 원자력 휴머니스트들에게는 그린피스나 기타 여러 반인륜적 집단들이 갖고 있는 풍부한 자원이 없다. 그러나 우리에게는 그런 종류의 자원이 필요한 것이 아니다. 우리에게는 그것보다 훨씬 더 중요한 진실이라는 자원이 있다는 사실을 결코 잊어서는 안될 것이다.

• Journal of Digital Convergence
• /
• v.15 no.4
• /
• pp.395-403
• /
• 2017

Narrators used to take an important role in the theatre of ancient Greece. They gave the audience an important information, explained the situations and conflicts between characters by talking to the audience directly. But in the realism play in the 20th century, which is represented as the 'fourth wall,' anything that can interrupt commitments of the audience such as a narrator, was excluded. However the two representative playwright in the 20th century, Thorton Wilder and Arthur Miller took narrators in their plays, Our Town and A View form the Bridge. This study shows why they adopted narrators in their play, which was unusual at that time and how this form of narrator affects to the meaning of the plays.

• Korean Journal of Social Welfare
• /
• v.59 no.4
• /
• pp.163-189
• /
• 2007

This study explores actual conditions and experiences on the rigor of social welfare qualitative researchers in Korea by using a qualitative inquiry. To examine the actual conditions on the rigor, this study analyzes 2,112 articles published in 8 Korean social work journals from 1979 to 2006. And to explores the experiences of social welfare qualitative researcher on the rigor, this study analyzes the experiences of qualitative research by using individual interviews and focus group interviews. The characteristics of social welfare qualitative research in Korea tend to enlarge according to the needs by doctoral candidates, coexist with post-positivism and constructivism. The analysis of both quantitative and qualitative results show that the rigor of social welfare qualitative research is very important to secure the validity and control the quality of qualitative research. Based on these results, this study introduced concrete tasks related to secure the rigor of social welfare qualitative research in Korea.