• Title/Summary/Keyword: 진단 접근법

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Condition Monitoring under In-situ Lubrication Status of Bearing Using Infrared Thermography (적외선열화상을 이용한 베어링의 실시간 윤활상태에 따른 상태감시에 관한 연구)

  • Kim, Dong-Yeon;Hong, Dong-Pyo;Yu, Chung-Hwan;Kim, Won-Tae
    • Journal of the Korean Society for Nondestructive Testing
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    • v.30 no.2
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    • pp.121-125
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    • 2010
  • The infrared thermography technology rather than traditional nondestructive methods has benefits with non-contact and non-destructive testings in measuring for the fault diagnosis of the rotating machine. In this work, condition monitoring measurements using this advantage of thermography were proposed. From this study, the novel approach for the damage detection of a rotating machine was conducted based on the spectrum analysis. As results, by adopting the ball bearing used in the rotating machine applied extensively, an spectrum analysis with thermal imaging experiment was performed. Also, as analysing the temperature characteristics obtained from the infrared thermography for in-situ rotating ball bearing under the lubrication condition, it was concluded that infrared thermography for condition monitoring in the rotating machine at real time could be utilized in many industrial fields.

Analytical trends in mass spectrometry based metabolomics approaches of neurochemicals for diagnosis of neurodegenerative disorders (퇴행성신경질환의 진단을 위한 신경전달물질 대사체의 질량 분석법 동향)

  • Lee, Na-Kyeong;Jeon, Won-Jei;Jeong, Seung-Woo;Byun, Jae-Sung;Lee, Wonwoong;Hong, Jongki
    • Analytical Science and Technology
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    • v.30 no.6
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    • pp.355-378
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    • 2017
  • Because neurochemicals are related to homeostasis and cognitive and behavioral functions in human body and because they enable the diagnosis of numerous neurodegenerative disorders, there has been increasing interest in the development of analytical platforms for neurochemical profiling in biological samples. In particular, mass spectrometry (MS)-based analytical methods combined with chromatographic separation have been widely used to profile neurochemicals in metabolic pathways. However, development of delicate sample preparation procedures and highly sensitive instrumental detection is necessary considering the trace levels and chemical instabilities of neurochemicals in biological samples. Therefore, in this review, analytical trends in MS-based metabolomics approaches to neurochemicals in multiple biological samples, such as urine, blood, CSF, and biological tissues, are discussed. This paper is expected to contribute to the development of an analytical platform to discover biomarkers that will aid diagnosis, prognosis, and treatment of neurodegenerative disorders.

SURGICAL REPAIR OF COMPLETE BONY BILATERAL CHOANAL ATRESIA VIA TRANSPALATAL APPROACH (완전 골성 양측성 후비공 폐쇄 환자의 구개부를 통한 외과적 치험례)

  • Kim, Kyoung-Won;Cho, Yong-Seok;Yang, Soo-Nam
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.20 no.2
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    • pp.133-138
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    • 1998
  • Choanal atresia may be membrane or bony, unilateral or bilateral. Approximately 90% of the choanal atresia are bony type. Unilateral choanal atresia often eludes the diagnosis because of the absence of subjective symptoms in the neonatal period. However, bilateral choanal atresia presents at birth with cyclic respiratory distress aggravated by feedings. So complete bilateral choanal atresia is considered as a neonatal emergency. Examinations for the diagnosis of chonal atresia include 1) attempt at passing a rubber catheter or probe through the patient s nose, 2) mirror examination of the nasopharynx, 3) digital examination of the nasopharynx, 4) X-ray examination after installation of radiopaque materal into the nasal cavity. But, computed tomography has become accepted method for evaluation of choanal atresia. Surgical repair of choanal atresia is accomplished via transnasal or transpalatal approach. Advantages of the transpalatal approach are improved exposure and the preservation of mucosal flap along the newly formed apertures. On the other hand, the transpalatal approach carries the risk of injury to the greater palatine neurovascular complex, and requires longer operative time. After careful physical and radiographic examinations, we accomplished the surgical repair of the complete bony bilateral choanal atresia via transpalatal approach without complications.

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Limitations of neurobiological approach convergent to neuropsychiatry: DCD and two visual systems theory (신경정신학에 융복합되는 신경생물학적 접근법의 한계점: 발달성 협응장애와 두 시각 이론에 관한 종설)

  • Lee, Young-Lim
    • Journal of Digital Convergence
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    • v.13 no.6
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    • pp.225-234
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    • 2015
  • Neurobiological approach helps to resolve the mind-body dualism and develop new assessment and treatment approaches in psychiatry. However, it could be a problem to place too much emphasis on certain aspects of neurobiology, specifically structural neuroanatomy, because of the complexity or comorbidity of neuropsychiatric disorders. Developmental Coordination Disorder (DCD), for instance, is generally related to problems in motor skills and this movement disability is often related to perception. One account, two visual systems theory, relied on functional distinction in brain; ventral stream is responsible for visual recognition, and dorsal stream is responsible for the guidance of actions. However, Studies are now showing that shape perception is relevant to visually guided action, such as reaching-to-grasp an object. In this article, I reviewed fundamental findings of two-visual system theory and suggested problems of visually guided action to consider what shape perception implies for the two visual systems. Questions raised highlight possible limitations of adopting a structural neuroanatomical approach to account for perception and action effects, and by extent related psychiatric conditions such as DCD. In conclusion, neurobiological approach converging to neuropsychiatry, while useful, would be limited if it focuses too much on anatomical distinction.

Forming Shop Analysis with Adaptive Systems Approach (적응시스템 접근법을 이용한 조선소 가공공장 분석)

  • Dong-Hun Shin;Jong-Hun Woo;Jang-Hyun Lee;Jong-Gye Shin
    • Journal of the Society of Naval Architects of Korea
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    • v.39 no.3
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    • pp.75-80
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    • 2002
  • In these days of severe struggle for existence, the world has changed a great deal to global and digital oriented period. The enterprises try to introduce new management and production system to adapt such a change. But, if the only new technologies are applied to an enterprise without definite analysis about manufacturing, failure fellows as a logical consequence. Hence, enterprise must analyze manufacturing system definitely and needs new methodologies to mitigate risk. This study suggests that the new approach, which is systems approach for process improvement, is organized to systems analysis, systems diagnosis, and systems verification. Systems analysis analyzes manufacturing systems with object-oriented methodology-UML(Unified Modeling language) from a point of product, process, and resource view. Systems diagnosis identifies the constraints to optimize the system through scientific management or TOC(Theory of constraints). Systems verification shows the solution with virtual manufacturing technique applied to the core problem which emerged from systems diagnosis. This research shows the artifacts to improve the productivity with the above methodology applied to forming shop. UML provides the definite tool for analysis and re-usability to adapt itself to environment easily. The logical tree of TOC represents logical tool to optimize the forming shop. Discrete event simulator-QUEST suggests the tool for making a decision to verify the optimized forming shop.

Repair of Morgagni Hernia through the Abdominal Approach - A case report - (복부접근법을 이용한 Morgagni Hernia의 교정 - 1예 보고 -)

  • Hwang, Jung-Joo;Kim, Do-Hyung;Lee, Yang-Deok;Kim, Kil-Dong
    • Journal of Chest Surgery
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    • v.40 no.10
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    • pp.722-725
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    • 2007
  • Morgagni's hernia constitutes about 3% of all the congenital diaphragm hernias. It is usually asymptomatic and it is frequently found coincidentally during routine diagnostic testing in adulthood. It is usually diagnosed by simple chest X-ray, but when this condition is without intestinal herniation, then chest CT or other modalities are necessary. Operative repair is desirable when there is the risk of strangulation of the intestine. The trans-thoracic or trans-abdominal approaches are possible to treat this malady. We report here on one case for which we successfully used a laparoscopic approach to treat this problem.

A Study on Research Topics for Thyroid Cancer in Korea (국내 갑상선암 연구 주제 동향 분석)

  • Yang, Ji-Yeon;Shin, Seung-Hyeok;Heo, Seong-Min;Lee, Tae-Gyeong
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2019.01a
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    • pp.409-410
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    • 2019
  • 본 논문에서는 국내 갑상선암의 연구 동향을 파악하기 위해 텍스트 중심의 접근법을 제안한다. 국내 갑상선암은 2000년대에 들어서며 발생이 급증하여 과잉진단의 논란을 불러일으켰으나, 다양한 분야의 자정 노력으로 수술 환자수가 크게 줄었다. 본 연구에서는 텍스트 마이닝 기술을 사용하여 디비피아에 등록되어 있는 갑상선암 관련 논문의 키워드와 초록을 수집하여 분석하였다. 1980년대는 대부분의 사례보고가 있었고 1990년대에 들어서면서 검진을 통한 조기 진단의 내용이 자주 나타났다. 2000년대에는 여러 장비들을 활용한 검사방법과 미세한 암의 발견에 대한 논의가 증가하였음을 확인 할 수 있었다. 2010년대에 들어서는 환자의 삶의 질에 대한 연구가 많이 이루어졌다. 지난 수십 년 동안 갑상선 암 연구 주제에 대해 뚜렷한 변화가 나타났으며, 향후 연구의 기초자료로 활용될 수 있으리라 기대된다.

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Glomerular Detection for Diagnosis of Lupus Nephritis using Deep Learning (딥러닝을 활용한 루푸스 신염 진단을 위한 생검 조직 내 사구체 검출)

  • Jung, Jehyun;Ha, Sukmin;Lim, Jongwoo;Kim, Hyunsung;Park, Hosub;Myung, Jaekyung
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2022.07a
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    • pp.85-87
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    • 2022
  • 루푸스 신염을 정확히 진단하기 위해서는 신장의 침 생검을 통한 조직검사를 통해 사구체들을 찾아내고, 각각의 염증 정도를 분류해야 한다. 하지만 이에는 의료진의 많은 시간과 노력이 소요된다. 따라서 본 연구에서는 이러한 한계를 극복하기 위해 합성곱 신경망 (Convolutional neural network, CNN)에 기반한 검출 및 분할에 딥 러닝 접근법을 적용하는 YOLOv5 알고리즘을 통해 검체 이미지 내에서 사구체를 자동으로 검출해 내도록 하였다. 그리고 루푸스 신염 환자의 슬라이드 이미지에 대한 태깅 작업을 거쳐 학습을 위한 데이터와 테스트를 위한 데이터를 생성하여 학습 및 테스트에 활용하였다. 그 결과 고화질의 검체 이미지 내에서 대부분의 사구체를 0.9 이상의 높은 precision과 recall로 검출해 낼 수 있었다. 이를 통해 신장 내부의 사구체 검출을 자동화하고 추후 연구를 통해 사구체 염증 정도를 단계화 할 수 있는 발판을 마련하였다.

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Task-Oriented Approaches to Developmental Coordination Disorder: A Literature Review (발달성협응장애와 과제-중심 접근법(task-oriented approach)에 대한 문헌 고찰)

  • Lee, Seung-Jin;Kim, Kyeong-Mi
    • The Journal of Korean Academy of Sensory Integration
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    • v.22 no.1
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    • pp.69-84
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    • 2024
  • Objective : This study aimed to provide an overview of task-oriented approaches for children with developmental coordination disorder, including its definition, diagnosis, causes, and assessment, through a literature review. Subject : Eighteen international articles published between January 2000 and September 2023 were analyzed to explore the intervention strategies of Neuromotor Task Training (NTT) and Cognitive Orientation to daily Occupational Performance (CO-OP). The objectives of the interventions mentioned in the reviewed articles were categorized according to the criteria of the Occupational Therapy Practice Framework-4 (OTPF-4). The results showed that NTT more frequently set goals in the area of client factors, while CO-OP set goals only in the area of occupation. This difference in goal setting can be explained by the strategy differences between the two interventions. Conclusion : A broader and deeper understanding of strategies for interventions with task-oriented approaches to developmental coordination disorder can increase awareness of the disorder and provide a more solid basis for evidence-based practice.

Blood Biomarkers for Alzheimer's Dementia Diagnosis (알츠하이머성 치매에서 혈액 진단을 위한 바이오마커)

  • Chang-Eun, Park
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.4
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    • pp.249-255
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    • 2022
  • Alzheimer's disease (AD) represents a major public health concern and has been identified as a research priority. Clinical research evidence supports that the core cerebrospinal fluid (CSF) biomarkers for AD, including amyloid-β (Aβ42), total tau (T-tau), and phosphorylated tau (P-tau), reflect key elements of AD pathophysiology. Nevertheless, advances in the clinical identification of new indicators will be critical not only for the discovery of sensitive, specific, and reliable biomarkers of preclinical AD pathology, but also for the development of tests that facilitate the early detection and differential diagnosis of dementia and disease progression monitoring. The early detection of AD in its presymptomatic stages would represent a great opportunity for earlier therapeutic intervention. The chance of successful treatment would be increased since interventions would be performed before extensive synaptic damage and neuronal loss would have occurred. In this study, the importance of developing an early diagnostic method using cognitive decline biomarkers that can discriminate between normal, mild cognitive impairment (MCI), and AD preclinical stages has been emphasized.