• Journal of Life Science
• /
• v.8 no.1
• /
• pp.72-84
• /
• 1998

Sprague Dawley rats(24 weeks of age) were divided and were given normal diet for 6 weeks, followed by normal diet and 2% cholesterol diet for 14 weeks. During these periods, 10 weeks’ exercises are performed after 4 weeks. And then we analyze the blood and adipose tissue by decapitating those rats. 1. Serum total cholesterol was enhenced by cholesterol diet, while aerobic exercise tended to reduce it. 2. Cholesterol diet slightly reduced serum HDL-C and LDL-c, where as aerobic exercise showed a tendency to decrease it. 3. Cholesterol diet slightly reduced phospholipid and triglyceride, but aerobic exercise showed a tendency to increase them. 4. Aerobic exercise significantly decreased adipose tissue in normal diet rats and tended to reduce it in cholesterol-dietary rats. These results suggest that aerobic exercise decrease serum total cholesterol and LDL-C, and as a result can prevent atherosclerosis.

• The Journal of Engineering Geology
• /
• v.14 no.3 s.40
• /
• pp.287-300
• /
• 2004

By using a simple conceptual model, a sensitivity analysis is performed to examine the effects of changing model parameters on the model outputs, the groundwater discharge and the radius of influence, induced by tunnel construction. The results indicate that the model outputs are most sensitive to the tunnel depth and the hydraulic conductivity, and their sensitivities vary with time. It is also revealed that the sensitivity of the specific yield in- creases constantly with time, and therefore it is as important as the hydraulic conductivity for constructing a wet-system tunnel. A transient model is suggested to simulate the stepwise tunnel excavation and the watertight lining. The model is used for a tunnel construction site to predict groundwater mow into the tunnel and the transient response of the surrounding aquifer system. The predicted results are highly sensitive to the hydraulic conductivites assigned by model calibration. Thus, a postaudit should be made to reduce the uncertainty of the predictive model.

• The Journal of Engineering Geology
• /
• v.25 no.1
• /
• pp.131-148
• /
• 2015

The purpose of this study is to analyze and compare the heat transfer efficiency of using copper pipe, stainless pipe and traditional PE pipe commonly used for geothermal heat exchanger, with aims at seeking improved methods. In addition, the varying efficiency of heat transfer from ground heat and groundwater heat was assessed and its applicability was discussed. Design parameters for empirical field study were derived by controlling flow rate, velocity and caliber of pipes of the heat exchanger after the thermal efficiency of the heat exchanger material was evaluated. The heat exchange efficiency and effective thermal conductivity were measured with changing pattern through field thermal efficiency and thermal response test. Experimental results show that the metal material showed higher heat transfer efficiency than the PE pipe. Although the heat transfer efficiency was not high with the increase of the pipe diameter in the flow rate, it was high with the increase of the pipe diameter in the velocity.

• The Journal of Engineering Geology
• /
• v.25 no.2
• /
• pp.273-280
• /
• 2015

Delays in horizontal well drilling when encountering heterogeneous sediments can have negative effects on the construction process at a riverbank filtration site. Grain size analysis, including calculation of the coefficient of uniformity and the coefficient of curvature, was conducted on soil samples collected at each drilling depth during the process of drilling horizontal wells. These results were then used to develop a linear equation for estimating drilling velocity using the coefficient of uniformity and the coefficient of curvature as inputs. Testing of the linear equation in other horizontal wells indicates that the equation is most appropriate for coarse-sand-sized and well-sorted sediment. Because this study was conducted in a region with small- to medium-sized streams, more data are needed from larger rivers to modify the general equation. Our results will provide better estimates of drilling velocity, in turn enabling more detailed design and more effective construction management at riverbank filtration sites.

• The Journal of Engineering Geology
• /
• v.28 no.3
• /
• pp.443-453
• /
• 2018

Radial collector wells have been widely used for large-capacity groundwater development in riparian environments, and many empirical equations have been developed for initial estimates of groundwater yield. We compare the initial yield estimates produced by several empirical equations for the radial collector well at the Anseongcheon stream site. The results of Babac's, Kordas', and Petrovic's methods are similar to the actual yield of $6,124m^3/d$, but Milojevic's method predicts a higher yield than the observed value. The conditions under which these methods are applicable explain the observed differences between the actual and estimated yields. The applicability of empirical equations is evaluated by changing the input variables of distance from well to river, number of horizontal wells, thickness of aquifer, length of horizontal well, and hydraulic conductivity. The results indicate that the conditions under which each method is applicable must be considered carefully when estimating groundwater yield, and hydraulic conductivity must be estimated accurately.

• Journal of Nutrition and Health
• /
• v.36 no.8
• /
• pp.834-840
• /
• 2003

To examine the effect of Saengshik on parameters related to hepatoprotective, anthropometric, blood pressure, serum lipid and blood related indices, nonalcoholic fatty liver subjects were treated with two meal portion of Saengshik in the replacement of meals for a period of three months. Weight, Body Mass Index (BMI) and systolic blood pressure were significantly decreased after the treatment. Chronically elevated serum aspartate aminotransferase (AST), gamma-Glutamyl transferase (r-GTP) and Alkaline Phosphatase (ALP) levels showed reduction to the near normal range. Serum total triglyceride level were reduced following the treatment. Whereas, there were no changes of serum total cholesterol with Saengshik consumption. Also, additional study was conducted to investigate the effect of Saengshik supplementation to high cholesterol and fat diet on lipid metabolism in rats. Male Spraque-Dawley rats were administrated hyperlipidemiainducing diet containing 1% cholesterol and 10% lard to induce hyperlipidemia for 4 weeks and were fed on diet containing Saengshik (30%, w/w) for 7 weeks. The feeding of diet containing 30% Shaengshik significantly decreased total cholesterol (TC) contents and total triglyceride. These results demonstrate Saengshik may be beneficial for fatty liver patients in improving their lipid metabolism.

• KSBB Journal
• /
• v.10 no.2
• /
• pp.204-211
• /
• 1995

A target-sensitive liposome was prepared by using a dioleoyl-phosphatidylethanolamine(DOPE) and a palmitic acid coupled antibody(p-IgG). For the preparation of stable PE-liposomes, the key factors such as antibody modification method with palmitic acrid, molar ratio of p-IgG to lipid and the amount of various additives, were examined. The optimum molar ratio of p-IgG to lipid was found to be $2.5{\times}10^{-4}$ and the final concentration of deoxycholate for the stable liposome formation was about 0.09%. Two kinds of target-sensitive liposomes, containing polyclonal anti-SRBC(Sheep Red Blood Cell)-antibody and monoclonal anti-${\beta}$-HCG(Human Chorionic Gonadotropin)-antibody, were successfully prepared. The destabilization of liposomes was examined by measuring the release of calcein entrapped in the liposome vesicles. Calcein was released only when the liposomes were contacted with the specific target cells. The calcein release with non-specific target cells was negligible. From this result, it is clear that p-IgG is indispensible for the maintenance of stable PE-liposome and the calcein release is mainly due to the specific interactions between the liposomes containing antibody and the target cells containing antigen.

• The Journal of Engineering Geology
• /
• v.21 no.1
• /
• pp.1-13
• /
• 2011

Joint roughness is one of the most important parameters in analysis of rock slope stability. Especially in probabilistic analysis, the random properties of joint roughness influence the probability of slope failure. Therefore, a large dataset on joint roughness is required for the probabilistic analysis but the traditional direct measurement of roughness in the field has some limitations. Terrestrial LiDAR has advantagess over traditional direct measurement in terms of cost and time. JRC (Joint Roughness Coefficient) was calculated from statistical parameters which are known from quantitative methods of converting the roughness of the material surface into JRC. The mean, standard deviation and distribution function of JRC were obtained, and we found that LiDAR is useful in obtaining large dataset for random variables.

• The Korean Journal of Food And Nutrition
• /
• v.30 no.1
• /
• pp.148-155
• /
• 2017

This study aimed to investigate the effect of acorn powder and starch on the blood parameters of mice fed a high-fat diet. The moisture, crude ash, crude protein, and crude fat contents of acorns were $37.99{\pm}0.37%$, $1.61{\pm}0.06%$, $4.36{\pm}0.18%$ and $3.22{\pm}0.15%$, respectively. Acorn powder and starch contains antioxidant minerals such as selenium and zinc. The iron content was significantly higher in acorn powder than in acorn starch (p<0.05). The total cholesterol concentration was $148.50{\pm}29.72mg/dL$ in the high-fat starch diet (HFS) group, while in the high-fat diet (HF) group it was $201.50{\pm}39.15mg/dL$ (p<0.05). Serum LDL-cholesterol concentrations were significantly lower in the HFS group ($50.50{\pm}10.79mg/dL$) than in the HF group ($62.00{\pm}20.85mg/dL$; p<0.05). The serum $IL-1{\beta}$ levels in mice were not significantly different between the groups. IL-10 levels were higher in the HFP group than other groups. There is a need for strong recognition that acorns are good ingredients worldwide. It is required to develop various products using acorn powder and starch powder. There is also a need for a strategy to globalize food using acorns.

• Journal of Korean Society for Geospatial Information Science
• /
• v.17 no.2
• /
• pp.61-69
• /
• 2009

In mid-July, 2006 the torrential rainfall across Gangwon-do region caused 48 casualties and 1,248 houses submerged, resulting in damages with the restoration costs of 3 trillion and 512.5 billion won. This was because the topographic characteristics of Gangwon-do region for which mountainous areas mostly account increased the effects of landslide. In this study, the landslide region was shot using the PKNU No.4 system immediately after the occurrence of landslide in order to analyze it as objectively, exactly, and rapidly as possible. 1,054 areas with landslide occurrence were extracted by digitizing the shot images through visual reading after orthometric correction using ERDAS 9.1. Using the Arc GIS 9.2, a GIS program, hydrologic, topographic, clinical, geologic, pedologic aspects and characteristics of the landslide region were established in database through overlay analysis of digital map, vegetation map, geologic map, and soil map, and the status and characteristics of the occurrence of the landslide were analyzed.