• Title/Summary/Keyword: 중간체

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Regional outbreak of staphylococcal scalded skin syndrome in healthy children (건강한 소아에서 포도알균화상피부증후군의 지역적 유행)

  • Do, Hyun Jeong;Park, Eun Sil;Lim, Jae Young;Park, Chan Hoo;Woo, Hyang Ok;Youn, Hee Shang;Seo, Ji Hyun
    • Clinical and Experimental Pediatrics
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    • v.53 no.1
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    • pp.48-55
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    • 2010
  • Purpose : Staphylococcal scalded skin syndrome (SSSS) is a relatively uncommon superficial blistering skin disease that is due to Staphylococcus aureus. We had experienced a regional outbreak of SSSS over 3 years in healthy children. Methods : We retrospectively reviewed the medical records of those patients diagnosed as SSSS. Most of neonatal cases were nosocomial infections and excluded from the analysis. The clinical features, laboratory findings, the isolation and antibiotic resistance of S. aureus, the antibiotic management and other supportive treatments were analyzed. Results : Fifty-five patients with SSSS were admitted to our hospital from October 2001 to September 2004. The median age of patients was 3.0 years. Of the 55 patients, 9 were the generalized type, 13 were the intermediate type and 33 were the scarletiniform rash. All the patients were living in neighborhood of the Jinju area. S. aureus were isolated from 9 of the patients and all of the isolated S. aureus were methicillin resistant. All the patients except two were treated with intravenous flocloxacillin or nafcillin and/or cefotaxime. All the patients recovered during the follow-up period of 2 to 3 weeks. Conclusion : We experienced a regional outbreak of SSSS in previous healthy children. Further study for finding the carriers of S. aureus caused SSSS and preventing the spread of this disease is needed. Additionally, guidelines for treating SSSS due to methicillin resistant S. aureus should be established.

Analysis of Nutrients Balance during Paddy Rice Cultivation (수도재배시 논에서의 영양물질 수지 분석)

  • Hwang, Ha-Sun;Jeon, Ji-Hong;Ham, Jong-Hwa;Yoon, Chun-Gyeong
    • Korean Journal of Ecology and Environment
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    • v.36 no.1 s.102
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    • pp.66-73
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    • 2003
  • Field experimental study was performed to evaluate water and nutrient balances in paddy rice culture. The water balance showed that outflow generally balanced the inflow showing that about half (47${\sim}$54%) of total outflow was lost by surface drainage. No significant effect of fertilization rate was observed from three treatments (150%, 100%, and 70% of standard fertilization) on both rice yield and nutrient outflow from surface drainage. Therefore, reducing nonpoint source nutrient loading by reducing fertilization may not work well in the range of normal paddy rice farming practice, and instead it could be achieved by reducing surface drainage outflow. Water-saving irrigation by reducing pending depth, raising ridge height in rice field, and minimizing forced surface drainage are suggested to reduce surface drainage outflow. These practices can save water and protect water quality, however, deviation from conventional standard practices might affect the rice yield and further investigations are necessary. It was demonstrated that rainfall affects nutrient net outflow and paddy rice culture might be beneficial to wafer quality protection under normal rainfall condition.

Species and Hybrid Identification of Genus Coreoleuciscus Species in Hwnag-ji Stream, Nakdong River Basin in Korea (낙동강 상류 황지천에 서식하는 쉬리속(genus Coreoleuciscus) 어류 집단의 종 동정 및 잡종 판별)

  • Song, Ha-Yoon;Kim, Jae-Hun;Seo, In-Young;Bang, In-Chul
    • Korean Journal of Ichthyology
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    • v.29 no.1
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    • pp.1-12
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    • 2017
  • A natural hybrid of interspecific between the Coreoleuciscus splendidus and C. aeruginos (Cypriniformes: Cyprinidae) was captured in the Hwang-ji Stream, a tributary of the Nakdong River basin in Korea. An interspecific hybrid between C. splendidus and C. aeruginos was genetically identified based on morphological characteristics and the sequence analysis of nuclear recombination activating gene 1 (RAG1) gene (1,334 bp) and mitochondrial cytochrome c oxidase subunit 1 (CO1) gene (1,551 bp). As a result of morphological variations, the natural hybrid appeared to have an intermediate character between two parental species (C. splendidus and C. aeruginos) in three variations of black array (s) on dorsal, caudal and anal fin rays. Phylogenetic analysis inferred from RAG1 and CO1 sequence data revealed that Coreoleuciscus populations from Hwang-ji stream consist of two pure Coreoleuciscus species and a hybrid individual group. The individuals were clearly identified the cross and reciprocal hybrid by CO1 gene analysis. In RAG1 gene, 13 nucleotide variation loci were detected and the hybrid individuals displayed the double peaks of sequence chromatograms at the 9 diagnostic positions. In this study, molecular data and morphological variations were clearly demonstrated that hybridization did occur between C. splendidus and C. aeruginos. However, F2 hybrid generation and reproductive capacity of F1 hybrid individuals were not demonstrated.

FPGA Mapping Incorporated with Multiplexer Tree Synthesis (멀티플렉서 트리 합성이 통합된 FPGA 매핑)

  • Kim, Kyosun
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.4
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    • pp.37-47
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    • 2016
  • The practical constraints on the commercial FPGAs which contain dedicated wide function multiplexers in their slice structure are incorporated with one of the most advanced FPGA mapping algorithms based on the AIG (And-Inverter Graph), one of the best logic representations in academia. As the first step of the mapping process, cuts are enumerated as intermediate structures. And then, the cuts which can be mapped to the multiplexers are recognized. Without any increased complexity, the delay and area of multiplexers as well as LUTs are calculated after checking the requirements for the tree construction such as symmetry and depth limit against dynamically changing mapping of neighboring nodes. Besides, the root positions of multiplexer trees are identified from the RTL code, and annotated to the AIG as AOs (Auxiliary Outputs). A new AIG embedding the multiplexer tree structures which are intentionally synthesized by Shannon expansion at the AOs, is overlapped with the optimized AIG. The lossless synthesis technique which employs FRAIG (Functionally Reduced AIG) is applied to this approach. The proposed approach and techniques are validated by implementing and applying them to two RISC processor examples, which yielded 13~30% area reduction, and up to 32% delay reduction. The research will be extended to take into account the constraints on the dedicated hardware for carry chains.

DRAM Package Substrate Using Aluminum Anodization (알루미늄 양극산화를 사용한 DRAM 패키지 기판)

  • Kim, Moon-Jung
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.47 no.4
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    • pp.69-74
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    • 2010
  • A new package substrate for dynamic random access memory(DRAM) devices has been developed using selective aluminum anodization. Unlike the conventional substrate structure commonly made by laminating epoxy-based core and copper clad, this substrate consists of bottom aluminum, middle anodic aluminum oxide and top copper. Anodization process on the aluminum substrate provides thick aluminum oxide used as a dielectric layer in the package substrate. Placing copper traces on the anodic aluminum oxide layer, the resulting two-layer metal structure is completed in the package substrate. Selective anodization process makes it possible to construct a fully filled via structure. Also, putting vias directly in the bonding pads and the ball pads in the substrate design, via in pad structure is applied in this work. These arrangement of via in pad and two-layer metal structure make routing easier and thus provide more design flexibility. In a substrate design, all signal lines are routed based on the transmission line scheme of finite-width coplanar waveguide or microstrip with a characteristic impedance of about $50{\Omega}$ for better signal transmission. The property and performance of anodic alumina based package substrate such as layer structure, design method, fabrication process and measurement characteristics are investigated in detail.

Breeding of Purple Flower-colored Dwarf 'Jiknyeo' from Hybridization of Campanula punctata Lam. × Campanula punctata Lam. var. rubriflora Mak. (애기초롱꽃(Campanula punctata Lam.)과 자주초롱꽃(C. punctata Lam. var. rubriflora Mak.)의 교잡을 통한 자주색 꽃을 가진 왜성 초롱꽃 '직녀' 육성)

  • Choi, Nam-Hee;Kim, Gyeong-Hee;Lim, Mi-Young;Kim, Zhoo-Hyeon;Jeong, Byoung-Ryong
    • Horticultural Science & Technology
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    • v.30 no.3
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    • pp.338-341
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    • 2012
  • Campanula, native to Korea, is potentially an attractive potted or bedding plant. Experiments were conducted to produce a $F_1$ hybrid plant for a reduced plant height, 'Jiknyeo', by a conventional cross breeding between C. punctata Lam. and C. punctata Lam. var. rubriflora Mak. The crossing was carried out in July 2001 and the seeds were harvested in October 2001. Seeds were stored for two months at $5^{\circ}C$ for vernalization, and then were sown in March 2002. The $F_1$ hybrid have a purple flower color, and decreased plant height, leaf length, leaf width, and peduncle length. Each flower maintained freshness for a period of 20 days on the average. The whole flowering period of a plant was four months. The plant has flowering characteristics of an indeterminate inflorescence, prefers low humidity during the whole cultivation period, and requires low temperature in winter for flower bud differentiation.

Isothermal Vapor-Liquid Equilibria at 333.15 K and Excess Molar Volumes and Refractive Indices at 303.15 K for the Mixtures of Propyl vinyl ether + Ethanol + Benzene (Propyl vinyl ether+Ethanol+Benzene 혼합계의 333.15 K에서의 등온 기액평형과 303.15 K에서의 과잉물성 및 굴절율편차)

  • Hwang, In-Chan;Park, So-Jin
    • Korean Chemical Engineering Research
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    • v.49 no.1
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    • pp.56-61
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    • 2011
  • Alkyl vinyl ethers such as methyl vinyl ether, propyl vinyl ether, isopropyl vinyl ether, butyl vinyl ether and isobutyl vinyl ether are usually used as industrial solvents and chemical intermediates in the chemical or pharmaceutical industry. Recently, they are popularly used as raw materials for polymer electrolyte membrane fuel cells and as cellulose dyeing assistants. However, very few investigations about process design and operation data were reported for alkyl vinyl ether compounds and there are no data for propyl vinyl ether(PVE) systems as far as we know. In this work, the isothermal VLE data are reported at 333.15 K for the ternary systems of {PVE + ethanol + benzene} by using headspace gas chromatography(HSGC) and these VLE data were correlated using Wilson, NRTL and UNIQUAC equations. The excess volumes($V^E$) and deviations in molar refractivity(${\Delta}R$) data are also reported for the sub binary systems {PVE + ethanol}, {ethanol + benzene} and {PVE + benzene} at 303.15 K. These data were correlated with Redlich-Kister equation. In addition, isoclines of $V^E$ and DR for ternary system {PVE + ethanol + benzene} were also calculated from Radojkovi equation.

An Introductory Research for Development of Soil Ecological Risk Assessment in Korea (토양생태 위해성평가 제도 국내 도입방안 연구)

  • An, Youn-Joo;Kim, Shin Woong;Moon, Jongmin;Jeong, Seung-Woo;Kim, Rog-Young;Yoon, Jeong-Ki;Kim, Tae-Seung
    • Journal of Korean Society of Environmental Engineers
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    • v.39 no.6
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    • pp.348-355
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    • 2017
  • Human activities have resulted in soil pollution problems to us. Human and ecological risk assessment have been suggested as an efficient environmental management strategy for protecting human and ecosystems from soil pollution. However, Korean environmental policy is currently focused on human protection, and fundamental researches for ecology protection are required for institutional frameworks. In this study, we developed a schematic frame of Korean soil ecological risk assessment, and suggested the basic information for its application. This study suggested a soil ecological risk assessment scheme consisting of 4 steps for derivation of Predicted-No-Effect-Concentration (PNEC): 1) ecotoxicity data collection and reliability determination, 2) data standardization, 3) evaluation of data completeness for PNEC calculation, and 4) determination of ecological-risk. The reliability determination of ecotoxicity data was performed using Reliability Index (RI), and the classification of domestic species, acute/chronic, toxicity endpoint, and soil properties was used for data cataloging. The PNEC calculation methodology was determined as low-reliability, middle-reliability, and high-reliability according to their quantitative and qualitative levels of ecotoxicity data. This study would be the introductory plan research for establishment of Korean soil ecological risk assessment, and it can be a fundamental framework to further develop guidelines of Korean environmental regulation.

Load Sharing Ratios Between the Cortex and Centrum in a Lumbar Vertebral Body with aging using Finite Element Method (유한 요소 법을 이용한 노화에 따른 요추의 피질 골과 해면 골 간의 하중 분담 비율)

  • Lim, JongWan
    • Journal of Biomedical Engineering Research
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    • v.37 no.2
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    • pp.90-103
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    • 2016
  • This research was aimed to analyze load sharing ratios between cortical shell and trabecular bone of a degraded lumbar vertebra with aging, and also evaluate elastic moduli assigned into an FE model, using finite element method. For the better analysis of trabecular bone, effective elastic moduli, that is, nominal elastic moduli divided by the volumetric porosities was used. The elastic moduli of the cortical shell suitable for the trabecular bone were obtained from the equations on the basis of idealized stress-strain relations, including areal porosities. To minimize numerical errors, p-element was used. Using eight parameters that refer to some published papers, the geometry of L3 with a removed posterior part. After the constant compressive displacement was applied, the load sharing ratios were obtained by using both every elastic strain energy and every vertical force between two bones in each 8-volume. As results, 1) according to an increase in age from 20-year to 80-year, load sharing ratios of trabecular bone decreased from 55% to 49%; 2) the maximal ratios of each bone were occurred in the mid-plane of centrums and the endplate of cortical shells, respectively; 3) effective elastic moduli assigned into a porous centrum/cortex were found to be adequate; 4) for load sharing ratios, the difference of two methods showed that the total ratios were almost same within less than 1% but the partial ratios at every depth were more or less different each other.

Improvement of Field Installation Method for Asphalt Concrete Pavement Strain Gauge (아스팔트 콘크리트 포장 변형률계 매설 방법 개선에 관한 연구)

  • Lee, Jae-Hoon;Kim, Ji-Won;Kim, Do-Hyung;Lee, Kwang-Ho
    • International Journal of Highway Engineering
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    • v.5 no.3 s.17
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    • pp.31-42
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    • 2003
  • The KHC Test Road project was initiated on 1991 to develop Korean Pavement Design Guide. It was constructed along the Joongbu Inland Expressway line between Yeoju and Gamgok. It is two-lane wide expressway containing fifteen asphalt and twenty-five Portland cement concrete test pavement sections. Various sensors were installed in the Test Road to evaluate the behavior of test pavement sections under the influence of traffic load and environmental change. The most important issues in the sensor installation are the accurate location and long-term survivability. They are directly influenced by the sensor installation methodology. The methodology for asphalt strain gages is mainly discussed in this paper because it is the second important sensors in the KHC Test Road project. In order to find the best methodology, we evaluated existing methodology from prior experience and several conducted test installations. We have tried mound, block out, and trench cuts since 2000. Among three methods, block out was the most effective one in terms of accurate location, long-term survivability, and material homogeneity. However, this method cannot be applied to the wearing coarse so that the mound method was used as an alternative. The block out method was applied to base and intermediate layers while the mound method was used to the wearing coarse. Three hundred seventy-four asphalt strain gauges were installed on asphalt pavement sections from September 3rd to November 18th in 2002. According to the sensor measurement evaluation, 6.3% of sensor demonstrated over ranged readings for mound method installation and 2.5% did for block out method installation. We lost only two sensors during the installation. It is 99.5% survival and it is excellent survival rate according to other experience.

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