• Journal of the Korean Society of Radiology
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• v.17 no.7
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• pp.1165-1170
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• 2023

In this study, we aimed to develop a cost-effective neuro-modulation device for use in neuroscientific and clinical medical imaging applications. To achieve this, we designed and fabricated a brain neuro-modulation device with a material cost of less than $500, and subsequently evaluated its performance. The measured performance was found to be comparable to existing medical devices (TENS), with the developed device being compact in size, measuring less than 3 cm by 3 cm. The outcomes of this study are expected to be applicable in accelerating research and development in related fields, as well as in the rapid commercialization of neuro-modulation technology. Furthermore, it is anticipated that this work will contribute to advancements in functional radiological medical imaging technology and enhance accessibility to brain science and brain stimulation technology.

• Journal of Digital Convergence
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• v.17 no.12
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• pp.319-327
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• 2019

The muscle activity and balance ability of the acute stroke patient has been checked by the functional electrical stimulation using biofeedback fusion postural control training in this study. Functional electrical stimulation using biofeedback fusion postural control training have been implemented on 15 trainees and general biofeedback fusion postural control training have been implemented on another 15 trainees for 30 minutes at 5 times per week during 8 weeks, and vastus lateralis, vastus medialis, rectus femoris and biceps femoris have been measured using the biceps femoris to evaluate the muscle activity of the lower extremity. The moving surface area, whole path length and limited of stability have been measured using biorecue to measure the balance ability. There was statistically meaningful difference on the vastus lateralis, vastus medialis, rectus femoris and biceps femoris in the muscle activity of the lower extremity and there was statistically meaningful difference on surface area, whole path length and limited of stability in the balancing ability. Based on above, it is realized that the functional electrical stimulation using biofeedback fusion postural control training is more effective than the general biofeedback fusion postural control training on the improvement of the muscle activity of the lower extremity and the balance ability.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.04a
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• pp.412-416
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• 2000

본 연구는 TV 화질 설정치를 조절하여 제시된 실제 TV 화질에 대한 감성 평가를 실시하여, TV 화질에 대한 심리적 차원이 어떻게 구성되어 있는지를 알아보고, 또한 TV 최적 화질을 결정하는 감성요인을 규명하기 위해 수행되었다. 피험자들은 다섯가지 TV 화질 변인 (밝기, 명암, 선명도, 색상, 색농도) 각각을 각각 네 수준으로 조절하여 제시하는 네 종류의 자극 (인물, 실내, 정물, 풍경)을 본 후, 각 화질에 대한 감성을 평가하였다. 그 결과 TV 화질에 대한 감성 차원은 "깔끔함"과 "화려함" 두 주된 요인으로 구분되었다. 그리고 가장 만족스러운 TV 화질을 결정하는 감성 요인으로는 "자연스럽다", "침울하다-산뜻하다", "거칠다-매끄럽다" 순으로 나타났다. 네 자극중에서 TV 최적 화질을 결정하는 공통적인 요인은 "자연스럽다"였다.로 나타났다. 네 자극중에서 TV 최적 화질을 결정하는 공통적인 요인은 "자연스럽다"였다.다"였다.t;였다.

• The Korean Journal of Zoology
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• v.34 no.1
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• pp.8-19
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• 1991

Atrial natriuretic peptide(ANP)의 유리기전에 대한 특성을 알아보고자, 흰쥐의 적출심장 관류모형을 사용하여 연구한 바 다음과 같은 결과를 얻었다. 1. 심방을 확장시켰을 때 ANP의 유리는 촉진되었다. 그러나 과용량을 부하하면 확장기간보다 회복기간에 ANP의 유리가 현저하게 증가하였다. 2. Epinephrine과 phenylephrine을 주입하면 ANP의 유리 량이 증가했으나, isoproterenol을 주입하면 심박수와 우심방 내압이 현저하게 증가했는데도 ANP의 유리량은 오히려 감소하였다 3. 미주신경을 자극하면 심박수의 현저한 감소에도 불구하고 ANP의 유리량은 증가하였다. 이상과 같은 결과에서 볼 때 결론적으로, 심방의 용량부하에 의해 심방근의 신장수용체가 자극을 받아 ANP의 유리가 촉진되는 것은 분명하고, 심방근이 확장할 때 보다는 확장 후 다시 원래의 길이로 환원될 때 ANP가 유리될 것으로 사료된다. 그리고 ANP의 유리에 대한 adrenergic조절은 o-receptor가 관련되어 있으며 심박수와 심방내압이 ANP의 유리를 변화시키는 데는 반드시 필수적인 인자가 아닌 것으로 여겨진다. 또한 특히 미주신경의 자극으로도 ANP의 유리가 조절될 수 있다는 것이 본 연구를 통해 새로이 발견되었다.

• Journal of Music and Human Behavior
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• v.16 no.1
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• pp.47-72
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• 2019

This study reviewed and analyzed English-written studies using a rhythmic tapping task for motor control of children with autism spectrum disorder (ASD). Inclusion criteria for the participants were children with ASD and typically developing (TD) children. The keywords used for the outcome variables included rhythmic tapping, timed movement, and synchronization. Ten studies were included in the final analysis. The included studies were analyzed in terms of target variables, auditory stimuli, and measurements. A meta-analysis was also conducted to examine how children with ASD performed rhythmic tapping tasks compared to children with TD. In the identified studies, five variables were used: timed movement control, timing reproduction, bimanual coordination, synchronization, and interpersonal synchronization. It was found that rhythmic tapping performance was analyzed in terms of accuracy and precision of the movement and reported as significantly correlated to social skills measures. The meta-analysis results showed that there were no significant differences between the ASD and TD groups in continuing rhythmic movements when the presented auditory stimuli ended, whereas there were significant group differences in their ability to maintain their motor performance consistently and to synchronize with auditory cue or with others. These results support the rhythmic tapping task as an effective measure for not only motor control but also social skills development in children with ASD.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.12
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• pp.6340-6345
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• 2013

This study examined the involvement of histamine in heat-induced changes in pulpal blood flow(PBF) to determine the mechanism of neurogenic inflammation in feline dental pulp. The experiments were carried out in 10 felines anesthetized with sodium pentobartial and histamine injected into the dental pulp through the external carotid artery. The change in the pulpal PBF was measured using a laser Doppler flowmeter(Periflux 4001, Stockholm, Sweden). The probe of laser Doppler flowmeter was placed on the buccal surface of the ipsilateral canine teeth. Heat was applied to the tooth using a heat stimulator controlled script file with an input/output device. The application of heat ($40-65^{\circ}C$) induced a significant increase in PBF. The application of histamine($5{\mu}g/kg/1ml$) followed by heat($45^{\circ}C$) resulted in an increase in PBF. Therefore, the results of the present study showed that heat and histamine are capable of vasoconstriction caused by neurogenic inflammation in feline dental pulp. In addition, neurogenic inflammation plays an active role in modulating the microcirculation of the dental pulp.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.6
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• pp.1505-1510
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• 2010

Response to nerve stimulation platform for implementing measures to detect finger movement has been functioning as an important factor. The finger movement of the muscle response to nerve stimulation and sensing Actuator for the H/W development is needed. In addition, a low power embedded CPU based on the top was used. H/W configuration portion of the isolation power, constant current control, High impedance INA, amplifier parts, and the stimulus mode and the Micro-control the status of current, AD converter Low Data obtained through the processing system is implemented.

• Journal of the Institute of Electronics and Information Engineers
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• v.49 no.10
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• pp.194-201
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• 2012

Moxibustion is utilized not only to cure disease but also to increase immunity. However, it may lead to undesired effects including severe pains(blisters and burns) because of the difficulty of controlling heat intensity. To overcome these problems we developed the RF heat stimulation system which can control stimulus. Also, we developed the RF stimulation protocol for effective heat transfer in subcutaneous tissue of rabbit. RF stimulator consists of a medical RF capacitive heating device, isolation probe, isolation plate, negative pressure control part and temperature measurement part. For the designed stimulus protocol, we measured the temperature distribution on epidermis and in subcutaneous(5mm, 10mm) area of rabbit during moxibustion. A stimulation protocol was designed by controlling the ON/OFF duty ratio, repeating number, and energy of applied pulse to get the temperature distribution similar with that by moxibustion. In results, the correlation coefficients between temperature distribution by moxibustion and that of stimulator were 95% and 91% from 5mm and 10mm thick respectively. However, temperature distribution on epidermis by stimulator was remarkably lower than that of the moxibustion. Finally, the RF stimulation system showed that it can not only transfer effectively heat similar with moxibustion to the subcutaneous area, but also the influence by unwanted side effects can be minimized.

• The Korean Journal of Pharmacology
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• v.30 no.1
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• pp.29-37
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• 1994

Inhibition of the nociceptive Tail Flick Reflex (TFR) was observed with electrical stimulation of the locus coeruleus/subcoeruleus (LC/SC) in the male Sprague - Dawley rats under light anesthesia, and the involved neurotransmitter (s) were characterized. Electrical stimulation of LC/SC induced the analgesia with the stimulation threshold (intensity of the current, given for 100 usec and in 100 Hz frequency, which caused the TF latency longer than 6.5 sec) around 55 uA. Intrathecal administrations of ${\alpha}_2$ antagonist, yohimbine (30 ug) or opioid antagonist, naloxone (20 ug) increased the stimulation threshold by 147% and 123% respectively (from 55 uA to 135 uA,9 and from 54 uA to 123 uA;P0.01, n=5, each). The basal TF latency without stimulation (3.1 sec) was reduced by the antagonists (to 2.5 sec by yohimbine, p<0.05, n=5; to 2.6 sec by naloxone, p<0.1, n=5), vehicle only did not show any effect. Noradrenaline(NA) in the spinal cord superfusates measured with HPLC was increased by the LC/SC stimulation, from 4.18 ng/ml before to 7.74 ng/ml after stimulation (P<0.05, n=10). The result suggest that analgesia induced by LC/SC stimulation is mediated, at least in part, by the noradrenergic system in which ${\alpha}_2$ receptor is involved, as well as the opioid system.

• Journal of Korean Ophthalmic Optics Society
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• v.15 no.3
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• pp.235-240
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• 2010

Purpose: In this study, we proposed a simple accommodation-dependent crystalline lens with a constant volume and homogeneous refractive index. Methods: We proposed a human crystalline lens with two aspheric surfaces. Two surfaces intersect in two points and straight line between two points was equator(2b). It assumed that the derivative in axial direction was zero at the equator and the radial derivative was zero at the vertex. Proposed human crystalline lens was divided by the equator into the anterior and posterior parts. It was assume that the volume of each part and refractive index of the human crystalline lens were constant during accommodation. Results: For the changes during accommodation, geometrical parameters were determined by different objective distances. Considering the constant volume of each part with the small decrement of the equator, we obtained the paraxial parameters, such as the anterior and posterior vertex radius of curvature and lens thickness. Compared with the experimental data published in the literature, calculated values using simple approximation showed similar change per accommodative stimulus. Conclusions: These results showed that proposed simple approximation using assumption of constant volume and refractive index of the human crystalline lens made it possible to predict changes of geometrical parameters during accommodation.