• Korean Journal of Veterinary Research
• /
• v.40 no.1
• /
• pp.1-16
• /
• 2000

Nowadays, mongolian gerbil is notably utilized for the research of brain and water deprivation because of a congenital incomplete willis circle structure in the brain, audiogenic seizure in low noise, and special cholesterol metabolism without water absorption for a long time. In this study, we are intend to identify the morphological changes of the catecholaminergic neuron of brain according to the time lapse in the condition of long term water deprivation. 55 mongolian gerbil were divided 10 groups(control, 1, 2, 3, 4, 5, 10, 15, 20, 42th day water deprivation group), of which each group include 5 mongolian gerbils and 5 normal mongolian gerbils in control group were also used for brain atlas as a control. The brains were observed by the immunohistochemical stain using the TH, DBH and PMNT antibody. The results were as followings; 1. The nerve fibers of the TH-immunoreactive neuron were observed only in the and corpus striatum of the telencephalon. 2. Intensity of the immunostain of the nerve fiber in the cerebral cortex and corpus striatum was decreased gradually day by day after water deprivation. 3. The TH-immunoreactive nerve cells were observed in the paraventricular and periventricular nucleus of the 3rd ventricular in the hypothalamus of mongolian gerbil but the number of nerve cells were decreased from the first day of the water deprivation to the 10th day and increased until the 20th day, after than redecreased from the 20th day by the continuous water deprivation. The number of nerve fibers in this area were increased in the first day, but decreased from the 2nd day of water deprivation. The shape and density of the dopamine secreting cells in the brain of mongolian gerbil by the immunoreactive stain were changed in the continuous water deprivation. In this results, we can conclude that dopamine concerned in the water metabolism of mongolian gerbil, and mongolian gerbil could be used as an animal model for the research of water deprivation.

• Journal of Chest Surgery
• /
• v.39 no.11 s.268
• /
• pp.822-827
• /
• 2006

Background: Lung transplantation is a definitive therapy for a variety of end stage lung diseases. Since 1996, we have performed thirteen cases of lung transplantation including two retransplantations, and we analyzed the outcomes, complications, and survivals of these patients. Material and Method: We retrospectively analyzed the medical records of thirteen cases from July, 1996 to July, 2005. Result: During the period, 11 patients had undergone 43 lung and heart-lung transplantations, and two patients had retransplantation due to allograft failure. Mean age of recipients were $45.2{\pm}10.7$ years(range, $25{\sim}59$). Early complications were bleeding, reperfusion injury, and infection and late complications were mainly infection and post-transplantation lymphoproliferative disease. Excluding the operative mortality, the mean survival period was 16.5 months($2{\sim}60$ months). Two retransplantations had been performed 2 weeks and 13 months after single lung transplantations. Conclusion: In order to achieve long term survival, early detection of complications and proper treatment in addition to surgical skills are necessary, and these efforts can promote better lung transplantation programs in the near future.

• The Korean Journal of Nuclear Medicine
• /
• v.28 no.3
• /
• pp.371-376
• /
• 1994

To reevaluate the clinical usefulness of erection penography for diffential diagnosis of impotence, we reviewed retrospectively the data of penography in 56 patients who were diagnosed as impotence by various diagnostic workup. Twelve normal males were studied as control group. Papaverine HCl 30mg was injected into the corpus cavernosum and simultaneously $^{99m}Tc$-HSA 20mCi was injected via an antecubital vein. After injection radioactivities in the penile area were detected for 30 minutes by gamma camera and time activity curve was displayed. We defined that transit time(TT) is the time to reach peak activity and erection persistent time(EPT) is the duration of time to maintain peak activity and venous index(VI) is the ratio of radioactivity($R_{30}/R_{max}$). The results were as follows. The TT of arteriogenic group($10.7{\pm}2.8min$) was significantly increased compared with those of control and venogenic groups(P<0.05, respectively). The EPT of venogenic group ($6.2{\pm}6.8min$) is significantly decreased compared with those of control and arteriogenic groups(P<0.05, respectively). The TT of psychogenic($15.2{\pm}5.5min$) is significantly increased compared with those of control and arteriogenic groups(P<0.05, respectively). In conclusion erection penography was very useful for the diagnosis of vascular and psychogenic impotence and for differentiation between arteriogenic and venogenic but it could not differentiate mixed type or neurogenic from vascular or psychogenic.

• Journal of Korea Spatial Information System Society
• /
• v.8 no.1 s.16
• /
• pp.107-118
• /
• 2006

In this paper, several network algorithms were tested to find an optimal one for telecommunication network design. Algorithms such as Dijkstra's shortest path algorithm, Ford-Bellman's shortest path algorithm, Prim's minimum spanning tree algorithm, and Kruscal's minimum spanning tree algorithm were reviewed and compared in terms of feasibility and resulted network construction cost. Then an optimal algorithm that is most suitable for telecommunication network design was selected. For more specific and quantitative analysis of the selected algorithm, it was implemented to a real telecommunication network construction site. The analyzed results showed that the suggested design method when compared with the conventional one, reduced the network construction cost considerably. The total network length estimated by the conventional method were 5267 meters while the suggested method resulted in 4807 meters. Thus the new method reduced the total network length by 8.7 percent which is equivalent to 97,469,000 Won of construction cost. Considering the frequent telecommunication network constructions, due to new urban developments in the nation, the economic benefit of the suggested telecommunication network design method will be significant. In addition to the construction cost savings, the suggested telecommunication network design procedure possesses several other economic benefits. Since the design procedure can be standardized and automatized, it can reduce the design cost itself and the skill acquirement periods required for new or inapt design crews. Further, due to the standardized and automatized design procedure, any telecommunication network design results can accessed more objectively.

• Analytical Science and Technology
• /
• v.31 no.1
• /
• pp.47-56
• /
• 2018

Finding the blood left at a crime scene is very important to reconstruct or solve a criminal case. Although numerous reagents have been developed for use at crime scenes, luminol is the most representative. Bluestar Forensic has been used in recent years, but is expensive and cannot be stored after preparation. This study aims to develop a new luminol reagent that can be stored for a long period of time while maintaining the chemiluminescence intensity at the level of Bluestar Forensic. Because luminol dissolves well in aqueous alkaline solutions, the use of sodium hydroxide in the preparation of luminol reagents can promote the decomposition of hydrogen peroxide. Magnesium sulfate, sodium silicate, and potassium triphosphate have been used as hydrogen peroxide stabilizers. The effects of the addition of these substances on the chemiluminescence emission intensity and the storage period of the luminol reagents were confirmed. The addition of a hydrogen peroxide stabilizer was shown to have no significant affect on the chemiluminescence emissions intensity or stabilized pH of the luminol reagent during storage. It also greatly increases the shelf life of the reagents. The use of magnesium sulfate as a hydrogen peroxide stabilizer is the most appropriate. When sodium perborate is used instead of hydrogen peroxide as an oxidizing agent, there is no significant change in the sensitivity and chemiluminescence emissions intensity, but the storage period is shortened. However, after the reaction with blood, the pH of the mixed solution does not increase significantly, and is judged to be more suitable than a reagent made of hydrogen peroxide.

• Explosives and Blasting
• /
• v.27 no.2
• /
• pp.33-41
• /
• 2009

Specific charge, also called powder factor, is defined as the total explosive mass in a blast divided with the total volume or weight of rock to be fragmented. It is a well-known fact that change in explosive consumption per ton or per cubic meter of rock is always a good indication of changed rock conditions. In mining, it is common to use explosive consumption per ton of ore as a measure of the blastability for rock. On the contrary, in civil engineering, it is common to use explosive consumption per cubic meter of rock. In this paper, we adopt the definition of the civil engineering because we are mainly concerned with tunnel blasting. Up to now, although various methods for tunnel blast design have been proposed, there are so many cases in which the proposed methods do not work well. These may be caused by the differences in rock conditions between countries or regions, and can give a serious technical difficulty to a contractor. But if we know the specific charge for a given rock, then the blast design can become much more easier. In this respect, we suggest an algorithm for tunnel blast design that can exactly produce the predetermined specific charge as a result of the design. The algorithm is based on the concept of assigning different fixation factors to various parts of tunnel section, and may be used in combination with the known methods of tunnel blast design.

• Journal of Environmental Impact Assessment
• /
• v.26 no.3
• /
• pp.195-206
• /
• 2017

Recently, Discussion about BIM based LID (Low Impact Development) facilities management system is activated because interest of LID technique for urban water cycle restoration is increasing. For this reason, this paper developed the auto-checking module of the BIM (Building Information Model) based supply output table. This module will be the foundation of the BIM based LID facilities total management system. The research order is composed like next follows: (1) Select target area, (2) Make BIM model of LID facilities and extract supply output table, (3) Develop comparison module, (4) Analysis results. As a result, the authors made 27 LID facilities and developed the supply output table comparison automation module. So, the authors could find differences of 2D design documents based supply output table and BIm based supply output table. So, the authors made an improvement suggestion of the design plan and could construct foundation of the BIM based LID facilities total management system.

• Journal of Science Education
• /
• v.34 no.2
• /
• pp.279-290
• /
• 2010

This study is to investigate the direction for management of informal science education center by survey of participants' satisfaction and implication. The place to study was Gwacheon National Science Museum in Kyung-gi province. $4,322m^2$ for the education space can make education done effectively. And attendees of their own education program are over 10,000 per year. 87 students who attend education program and 78 of their parents joined the survey of participants' satisfaction. The results of this study show that most of the participants want informal science education center to be able to make up for school education in part of promoting scientific literacy, heuristic method and scientific attitude. Things to be improved were feedback about student activity, segmentation of the education program for each grade, public relations exercise of program and advanced method of teaching based on each subject of classes. As ideas for improvement, it seemed that making long term program for continuous participant, limiting participant appropriately, developing guide manual of teaching, improving publicity of program were required.

• Journal of Food Hygiene and Safety
• /
• v.22 no.2
• /
• pp.110-115
• /
• 2007

This test was performed to evaluate the skin irritation and sensitization of Creocomplex, disinfectant, Containing 10% 4-chloro-m-cresol, 10% didecyl dimethyl ammonium chloride, and 10% glutaraldehyde. In primary skin irritation test, rabbits were dermally treated with Creocomplex for 24 hrs. The disinfectant did not induce any adverse reactions such as erythema and edema on intact skin sites, but on abraded skin sites, some rabbits showed very slight erythema and edema 24hr after topical application. So, the disinfectant was classified as a practically non-irrifating material based on the score 0.13 of primary irritation index. In the skin sensitization test, guinea pigs were sensitized with intradermal injection of 0.1ml Creocomplex for 24 hr. After 1 week, Creocomplex was treated on the site of injection, and challenged 2 weeks later. Creocomplex did not induce any allergic reactions. Therefore, 10% Creocomplex was graded as a weak material from 0 in both sensitization score· and rate. From results of the present study, it is suggested that 10% Creocomplex does not cause contact irritation and sensitization.

• Journal of the Korean Society of Fisheries and Ocean Technology
• /
• v.55 no.4
• /
• pp.294-302
• /
• 2019

As a series of fundamental researches on the development of an automatic identification monitoring system for fishing gear. Firstly, the study on the installation method of automated identification buoy for the coastal improvement net fishing net with many loss problems on the west coast was carried out. Secondly, the study was conducted find out how to install an automatic identification buoy for coastal gill net which has the highest loss rate among the fisheries. GPS for fishing was used six times in the coastal waters around Seogwipo city in Jeju Island to determine the developmental status and underwater behavior to conduct a field survey. Next, a questionnaire was administered in parallel on the type of loss and the quantity and location of fishing gear to be developed and the water transmitter. In the field experiment, the data collection was possible from a minimum of 13 hours, ten minutes to a maximum of 20 hours and ten minutes using GPS, identifying the development status and underwater behavior of the coastal gillnet fishing gear. The result of the survey showed that the loss of coastal net fishing gear was in the following order: net (27.3%), full fishing gear (24.2%), buoys, and anchors (18.2%). The causes were active algae (50.0%), fish catches (33.3%) and natural disasters (12.5%). To solve this problem, the installation method is to attach one and two electronic buoys to top of each end of the fishing gear, and one underwater transmitter at both ends of the float line connected to the anchor. By identifying and managing abnormal conditions such as damage or loss of fishing gear due to external factors such as potent algae and cutting of fishing gear, loss of fishing gear can be reduced. If the lost fishing gear is found, it will be efficiently collected.