• Journal of dental hygiene science
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• v.3 no.1
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• pp.11-14
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• 2003

A methylotrophic Actinomycetes strain, which produce the anti-oral cancer activity compound, was isolated from soil and estimated as Amylocolatosis sp. based on taxonomic studies. A methanol didn't have influence on the production of the anticancer compounds. These compound were isolated by ethylacetate extract, silica gel column chromatography, sephadex LH-20 column and reverse phase HPLC. The compounds were very stable under heat ($121^{\circ}C$), acid(pH 2.0) and alkali(pH 11.0) treatment. The cytotoxic effect of isolated anticancer compounds on various cancer cell lines such as A549, SNU-1, KB, L1210, and Sarcoma 180 was investigated by MTT assay method. And these produced compounds also showed the broad antimicrobial spectrum to test strains such as bacteria and yeast.

• Transactions of the Korean Society of Mechanical Engineers
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• v.10 no.1
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• pp.25-33
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• 1986

In this paper, the frontal method based elastic-plastic F.E.M. program for mini-computer was developed. Since, the executable source program size was restricted by the system core memory size on the mini-computer, the active variables were memorized by the element base and the nonactive varables were memorized to the external disc file. The active variables of the finally developed program were reduced enough to execute about 1,000 freedom finite element on the mini-computer on which available variables were restricted as 32,767 integers. A modified CT fracture test specimen was examined to test the developed program. The calculated results were compared with experimental results concerning on the crack tip plastic deformation zone. Recrystallization technique was adopted to visualize the intensive plastic deformation regions. The Von-Mises criterion based calculation results were well agreed with the experimental results in the intensive plastic region which was over than 2% offset strain. The F.E.M. results using the developed program were well agreed with the theoritical plastic boundary which was calculated by the stress intensity factor as r$_{p}$=(K$_{1}$$^{2}$/2.pi..sigma.$_{y}$$^{2}$).f(.theta.).).).

• Journal of the Korean Institute of Telematics and Electronics S
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• v.36S no.8
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• pp.30-38
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• 1999

On providing MPEG-2 video service through the ATM network, it is necessary for network provider to have the ATM QoS objectives in order to guarantee quality of service required by end users at the application layer. In this paper, the degradation of QoS caused by cell losses at application layer is assessed quantitatively by GIQ model considering AAL layer and is evaluated qualitatively by MOS from the viewpoint of the end users in order to analyze the relation between CLR and QoS of MPEG-2 video. From the simulation and empirical results, we know that CLR and $GIQ_{mean}$ for guaranteeing QoS of MOS grade 5(Excellent) are $CLR{\le}4{\times}10^7$ & $GIQ_{mean}{\ge}99.4%$ and those for guaranteeing QoS of MOS grade 4(Good) are $CLR{\le}2{\times}10^6$ & $GIQ_{mean}{\ge}99.705%$.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.40 no.11
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• pp.913-918
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• 2016

A three-way reversing valve, which provides rapid and accurate changes in the water flow direction without requiring any precise control device, is used in automotive washing machines to remove oil and dirt that remain on the machined engine and transmission blocks. Because of the complicated shape of the bottom-plug, however, cavitation occurs in the plug. In this study, the cavitation index and POC (percent of cavitation) were used to quantitatively evaluate the cavitation effect occurring in the bottom-plug on the downstream side. An optimal shape design was conducted via parametric study with a simple CAE model to avoid time-consuming CFD analysis and hard-to-achieve convergence. To verify the results of the numerical analysis, a flow visualization test was conducted using a specimen prepared according to ISA-RP75.23. In this test, the flow characteristics, such as cavitation occurring on the downstream side, were investigated using flow test equipment that included a valve, pump, flow control system, and high-speed camera.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.37 no.3
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• pp.303-311
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• 2013

This research deals with the analysis and design of a driving mechanism for an automatic pneumatic drug injector, which can precisely control the injection volume using a relatively simple friction-driven mechanism, without any complicated control system. Through a dynamic analysis, the effects of the design parameters of the driving mechanism associated with the geometry, spring stiffness, and fiction are analyzed, and the results are reflected in a proto-type drug injector design, which is under development for mass production. A test is performed to assess the durability of the mechanism for up to one million operations, and comparison of its displacement after one million operations, verifies the mechanism's durability.

• Journal of Astronomy and Space Sciences
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• v.14 no.1
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• pp.136-141
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• 1997

To calculate the position and velocity of the artificial satellite precisely, one has to build a mathematical model concerning the perturbations by understanding and analysing the space environment correctly and then quantifying. Due to these space environment model, the total acceleration of the artificial satellite can be expressed as the 2nd order differential equation and we build an orbit propagation algorithm by integrating twice this equation by using the Cowell's method which gives the position and velocity of the artificial satellite at any given time. Perturbations important for the orbits of geostationary spacecraft are the Earth's gravitational potential, the gravitational influences of the sun and moon, and the solar radiation pressure. For precise orbit propagation in Cowell' method, 40 x 40 spherical harmonic coefficients can be applied and the JPL DE403 ephemeris files were used to generate the range from earth to sun and moon and 8th order Runge-Kutta single step method with variable step-size control is used to integrate the the orbit propagation equations.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.42 no.2 s.302
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• pp.1-10
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• 2005

This paper presents a technique for localization of a mobile robot using a single ultrasonic sensor. The mobile robot is designed for operating in a well-structured environment that can be represented by planes, edges, corners and cylinders in the view of structural features. In the case of ultrasonic sensors, these features have the range information in the form of the arc of a circle that is generally named as RCD (Region of Constant Depth). Localization is the continual provision of a knowledge of position which is deduced from it's a priori position estimation. The environment of a robot is modeled into a two dimensional grid map. we defines a physically-based sonar sensor model and employs an extended Kalman filter to estimate position of the robot. The performance and simplicity of the approach is demonstrated with the results produced by sets of experiments using a mobile robot.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.19 no.1 s.71
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• pp.1-13
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• 2006

An analytical procedure to analyze reinforced concrete(RC) beams and columns subject to monotonic and cyclic loadings is proposed on the basis of the layered section method. In contrast to the classical nonlinear approaches adopting the perfect bond assumption, the bond slip effect along the reinforcing bar is quantified with the force equilibrium and compatibility condition at the post cracking stage and its contribution is implemented into the reinforcing. The advantage of the proposed analytical procedure, therefore, will be on the consideration of the bond slip effect while using the classical layered section method without additional consideration such as taking the double nodes. Through correlation studies between experimental data and analytical results, it Is verified that the proposed analytical procedure can effectively simulate the cracking behavior of RC beams and columns accompanying the stiffness degradation caused by the bond slip.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.22 no.4
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• pp.299-306
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• 2009

Design optimization is a method to find optimum point which minimizes the objective function while satisfying design constraints. The conventional optimization does not consider the uncertainty originated from modeling or manufacturing process, so optimum point often locates on the boundaries of constraints. Reliability based design optimization includes optimization technique and reliability analysis that calculates the reliability of the system. Reliability analysis can be classified into simulation method, fast probability integration method, and moment-based reliability method. In most generally used MPP based reliability analysis, which is one of fast probability integration method, if many MPP points exist, cost and numerical error can increase in the process of transforming constraints into standard normal distribution space. In this paper, multiplicative decomposition method is used as a reliability analysis for RBDO, and sensitivity analysis is performed to apply gradient based optimization algorithm. To illustrate whole process of RBDO mathematical and engineering examples are illustrated.

• Journal of the Earthquake Engineering Society of Korea
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• v.8 no.3
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• pp.43-52
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• 2004

This paper describes a method of evaluating seismic system performance of highway transportation network in California. The basic element that plays a crucial role in this study is the fragility information of highway bridges in Caltrans' (California Department of Transportation) freeway network. The bridge fragility information is expressed as a function of the ground motion intensity, such as peak ground acceleration (PGA) or peak ground velocity (PGV). Network damage was evaluated under the 1994 Northridge earthquake and scenario earthquakes. A probabilistic model was developed to determine the effect of repair of bridge damage on the improvement of the network performance as days passed after the event. As an example, the system performance degradation measured in terms of an index, “Drivers Delay”, is calculated for the Los Angeles area transportation system, and losses due to Drivers Delay with and without retrofit were estimated.