• Journal of Veterinary Clinics
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• v.27 no.5
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• pp.588-592
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• 2010

A 15-year-old neutered male Yorkshire terrier was presented with a gait disorder of the pelvic limbs. For differential diagnosis of neural disease, magnetic resonance imaging (MRI) and computed tomography (CT) scan were performed. CT showed bone defect in the 4th lumbar vertebra and adjacent soft tissue mass. MRI revealed a mass in left side of the 4th lumbar vertebra. The mass was uniformly enhanced on contrast-enhanced T1-weighted imaging (T1W1). Excision of the mass alleviated back pain. Vertebral osteosarcoma was identified by the histopathological examination. Therefore, CT and MRI were helpful to diagnose vertebral osteosarcoma in the dog and to plan surgical excision of the mass.

• Journal of radiological science and technology
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• v.47 no.1
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• pp.21-28
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• 2024

This study was purpose to quantitative evaluation of comparison of the image intensity uniformity and noise power spectrum (NPS) by using American college of radiology (ACR) phantom for magnetic resonance imaging (MRI). The MRI was used achiva 3.0T MRI and discovery MR 750, 3.0T, the head and neck matrix shim SENSE head coil were 32 channels receive MR coil. The MRI was used parameters of image sequence for ACR standard and general hospital. NPS value of the ACR standard T2 vertical image in GE equipment was 7.65E-06 when the frequency was 1.0 mm^-1. And the NPS value of the ACR hospital T1 region of interest (ROI) 9 over all vertical image in Philips equipment was 9E-08 when the frequency was 1.0 mm^-1 and the NPS value of the hospital T2 ROI 9 over all vertical image in Philips equipment was 1.06E-07 when the frequency was 1.0 mm^-1. NPS was used efficiently by using a general hospital vertical sequence more than the standard vertical sequence method by using the ACR phantom. Furthermore NPS was the quantitative quality assurance (QA) assessment method for noise and image intensity uniformity characteristics was applied mutatis mutandis, and the results values of the physical imaging NPS of the 3.0T MRI and ACR phantom were presented.

• Journal of radiological science and technology
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• v.42 no.5
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• pp.329-334
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• 2019

This study was purpose to quantitative evaluation of noise power spectrum(NPS) and studied the quantitative evaluation and characteristics of modulation transfer function(MTF) by obtain the optimal edge image by using Coil in magnetic resonance imaging(MRI) equipment through Fujita theory using edge method. The MRI equipment was used (Tim AVANTO 1.5T, Siemense healthcare system, Germany) and the head matrix coil were 12channels(elements) receive coil. The NPS results of showed the best value of 0.004 based on the T2 Nyquist frequency of $1.0mm^{-1}$, and the MTF results of showed that the T1 and T2 values were generally better than the T1 CE and T1 CE FC values. The characteristics of this study were to explain the characteristic method of image quality evaluation in general. To present the quantitative evaluation process and results in the evaluation of MRI image characteristics in radiology.

• Investigative Magnetic Resonance Imaging
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• v.6 no.1
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• pp.28-34
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• 2002

Purpose : The minimum stimulus onset asynchronoy(SOAmin) is one of important experimental parameters for an event-related fMRI experiment designed with the stochastic stimulus. In this study, the most efficient SOAmin is explored for the stronger activation in motor and language tasks with the stimulus designed stochastically. Materials and methods : The event-related fMRI during motor and language tasks were obtained in four normal right-handed subjects. EPI-BOLD sequence is used at 1.5Tesla MR system for the acquisition of event-related fMRI. For each task the subjects are responded for the stimulus' with 2, 3, 4, and 6 seconds SOAmin. The obtained images are processed with SPM99, and the p value is set as 0.05 for the significant activation detection. The Z value and the number of activated pixels are compared for each task. Results : For the motor task, the primary and supplementary motor areas are activated, and for the language task the consistent activated signals are detected in the Broca's. The activated signal is to be stronger for the shorter SOAmin for both motor and language tasks. At primary motor area, the activated signals is the strongest for 3 seconds SOAmin and for the supplementary motor area the result with 2 seconds SOAmin shows the strongest activation. And the result of language task shows the strongest activation at the 2 seconds SOAmin. Conclusion : In the event-related fMRI of motor and language tasks with the stochastically designed stimulus, the 2 or 3 seconds SOAmin is efficient for more activated and clustered activation.

• Investigative Magnetic Resonance Imaging
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• v.4 no.1
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• pp.52-57
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• 2000

Purpose : The purpose of this study was to investigate the pattern of cerebral response to motor tasks in patients with schizophrenia compared with normal subjects using functional MRI. Materials and methods ; Nine right handed-schizophrenic patients and six right-handed normal subjects were included. We used right hand movement as task. Series of 120 consecutive echo-planar images per section were acquired during three cycles of task and rest activations. Lateralization index of cortical response was measured and compared between patients and normal subjects. Results ; Right hand motor task was associated with greater activation in left sensorimotor cortex than the right in normal subjects. Schizophrenia patients showed relatively decreased activation in left cortex and increased activation in right cortex compared with normal subjects. In one patient, reversed lateralization was noted. Conclusion : Normal hemispheric asymmetry of cortical response to motor task was found in different pattern in schizophrenia. Our result is consistent with functional disturbance of motor circuitry in this disorder. Functional MRI will play an important role in diagnosis and research of this disorder.

• Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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• 2003.10a
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• pp.151-152
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• 2003

최근 NMR, MRI, x-선 등 전자파의 기술이 발전되면서 이들을 이용하여 내부품질을 검출하는 보다진보된 연구가 수행되고 있다. 관련 연구로는 자기공명영상을 이용하여 내공수삼 및 정상수삼의 내부를 촬영하여 T$_1$, T$_2$의 값을 측정하여 내부조직의 이상유무를 추정하였고, 또한 MRI에 의해 수삼의 내부품질 뿐만 아니라 연근 판정 가능성을 검토하는 등 많은 연구가 수행되고있다. 이 연구에서는 MRI 시스템을 이용하여 수삼의 내부단면 영상을 획득하여 내부결함 유무를 검출하고, 또한 동일한 수삼을 대상으로 홍삼 제조 후 내부품질의 변화 특성을 조사하고자 수행하였다. 공시재료는 충북 음성에 있는 인삼연초연구원에서 4~6년 근 된 수삼을 이용하였고, 시험 장비로는 국내 MRI 생산 전문 업체인 ISOL Tech. Co.에서 개발한 의료용 장비인 CHORUS 1.5T(자속밀도 1.5 Tesla)를 이용하였다. 슬라이스 두께/간격은 5mn/5mn, 촬영 단면수는 15장/시료, 영상영역(FOV)은 180mmx90mm, image size는 256$\times$128 pixels 그리고 TR/TE는 각각의 이완상수별로 500/13(Tl), 4,000/63(T2) 및 2,200/21(Pd)에 대한 단면영상을 얻었다. 5개의 수삼을 동시에 뇌두에서 뿌리 쪽으로 MR 단면영상을 획득하였다. 이완상수 T$_1$, T$_2$, Pd에 대해서 MR 영상을 획득하였으며, 총 15장의 단면 영상 중 내부 상태를 가장 잘 식별 할 수 있는 영상을 조사한 결과 T$_1$과 Pd에서 촬영한 영상에서는 내부상태가 잘 나타났으나, T$_2$에서 얻은 영상은 영상의 손실이 많이 발생되었다. 한편, T$_1$에 대해서 뇌두에서 뿌리쪽으로 가면서 각 위치에 따라 수삼 내부의 부패된 영상이 나타나 이에 대한 판정은 가능한 것으로 나타났다. 2000년도와 2001년도에 각각 수확.저장된 수삼을 부위별로 단면영상을 MRI로 측정하고, 그 시료를 인삼연초연구원(음성시험장)에서 홍삼으로 제조한 후 수삼 상태에서의 내부품질과 홍삼으로 제조된 후의 내부품질 변화를 조사하였다. 총 20본의 수삼을 MRI 시스템으로 영상을 획득하였고, 모든 시료에 대해서 내부조직의 상태를 관찰하였다. 수삼의 수분함량은 뇌두로부터 1cm부위를 절단하여 조사하였고, 수삼조직은 절단시 단면의 달관 조사에 의한 성적이며 홍삼품질은 제조삼의 조직상태를 절단하여 육안판별로 검사하였다. 총 20본의 수삼 중 정상은 16본 이었고, 이들은 홍삼으로 제조된 후 내공 내백 등이 혼재되어 나타났으며 정상수삼이 정상홍삼으로 나타난 경우는 5본이었고, 내백은 5본, 내공은 6본으로 조사되었다. 또한 수삼에서 4본은 썩은 부위가 포함되어있는 수삼이었는데 홍삼으로 제조되었을 때 3본은 내백으로 되었고 1 본은 수삼에서 썩은 부위가 1/4정도로 미미해서 홍삼 제조시 정상으로 나타났다. 일반적으로 홍삼 제조시 내공의 발생은 제조공정에서 나타나는 경우가 많으며, 내백의 경우는 홍삼으로 가공되면서 발생하는 경우가 있고, 인삼이 성장될 때 부분적인 영양상태의 불충분이나 기후 등에 따른 영향을 받을 수 있기 때문에 앞으로 이에 대한 많은 연구가 이루어져야할 것으로 판단된다.

• Investigative Magnetic Resonance Imaging
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• v.12 no.2
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• pp.170-177
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• 2008

Purpose : To evaluate usefulness of MR imaging after serial brain US in the high-risk neonates before discharge of the neonatal intensive care unit. Materials and Methods : Retrospective comparison of 412 US and 121 MR scans in 121 neonates and young infants were performed. Grading of germinal matrix/intraventricular hemorrhage (GMH/IVH) was performed and presence of intracranial hemorrhage other than GMH/IVH and parencyma lesions was also analyzed. Results : Among the 242 lateral ventricles, Seven GMH and 46 IVH were additionally detected by MRI. On the other hand, 30 GMH were only detected by US. US demonstrated Grade 1/2/3/4 GMH/IVH in 24/8/13/0 ventricles each, while each grades were identified in 3, 49, 10, 2 ventricles on MR images. Other intracranial lesions additionally detected on MR images were cerebral hemorrhage (n=4), cerebellar hemorrhage (n=4), extraaxial hemorrhage (n=8), diffuse excessive signal change of the white matter (n=72), non-cavitary lesion (n=4), encephalomalacia (n=2), and ventriculomegaly (n=5). Conclusion : MR imaging could be an excellent complimentary study after serial brain US for additional detection of the intracranial pathology, particularly IVH and white matter lesions, though US would be better in follow-up of GMH in some neonates.

• Korean Journal of Cognitive Science
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• v.19 no.1
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• pp.75-88
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• 2008

Visual scene contains lots of redundant information. To process this redundant information without increasing brain's volume, human visual system may summarize incoming information. If similar but different information are given to visual system, visual system extracts statistical properties of the information. One example of the statistical representation is representation of mean size. The mean representation is accurate and durable. The process of mean representation is suggested to be parallel. However, previous studies on the mean representation mostly used behavioral methods. The purpose of this study was to investigate which neural regions extracted the mean size of a set of circles using fMRI method. According to previous studies, BOLD signal of certain areas that were in charge of cousin stimuli decreased when the same stimuli presented repetitively. We used this paradigm and found that BOLD signal of right occipital area was decreased when same mean site was presented repeatedly. This results suggest that right occipital area is the locus of mean representation of visual stimuli.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.34 no.3
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• pp.80-91
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• 2021

Objective : The purpose of this study is to discriminate the vestibular schwannoma misdiagnosed as Idiopathic Sudden Sensorineural Hearing Loss. Methods : A 46-year-old female patient who was suffering left sudden sensorineural hearing loss(SSNHL), visited after diagnosed as Idiopathic SSNHL by previous hospital. For diagnosing the vestibular schwannoma, we conducted the Puretone audiometry, auditory brainstem response threshold test and magnetic resonance imaging(MRI) for temporal bone with enhancement. Result : Auditory Brainstem Response threshold test was abnormal and in enhanced MRI, the vestibular schwannoma in left side was detected. The patient was discharged from the hospital for tertiary hospital care. Conclusions : When the patient with SSNHL visits a hospital even if after diagnosed as Idiopathic SSNHL by previous hospital, a doctor should keep in mind the possibility of vestibular schwannoma.

• Investigative Magnetic Resonance Imaging
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• v.14 no.2
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• pp.95-102
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• 2010

Purpose : To evaluate the magnetic resonance imaging (MRI) and clinicopathological features of triple negative breast cancer, and compare them with those of non-triple negative breast cancer. Materials and Methods : This study included 231 pathologically confirmed breast cancers from January 2007 to May 2008. We retrospectively reviewed the MRI findings according to the Breast Imaging Reporting and Data System (BI-RADS) lexicon: mass or non-mass type, mass shape, mass margin, non-mass distribution, and enhancement pattern. Histologic type, histologic grade, and the results for epidermal growth factor receptor, p53, and Ki 67 were reviewed. Results : Of 231 patients, 43(18.6%) were triple negative breast cancer. Forty triple negative breast cancers (93.0%) were mass-type lesion on MRI. A round or oval or lobular shape (p=0.006) and rim enhancement (p=0.004) were significantly more in triple negative breast cancer than non- triple negative breast cancer. In contrast, irregular shape (p=0.006) and spiculated margins (p=0.032) were significantly more in non-triple negative breast cancer. Old age (p=0.019), high histologic grade (p<0.0001), EGFR positivity (p<0.0001), p53 overexpression (p=0.038), and Ki 67 expression (<0.0001) were significantly associated with the triple negative breast cancer. Conclusion : MRI finding may be helpful for differentiation between triple negative and non-triple negative breast cancer.