• Korean journal of applied entomology
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• v.18 no.1 s.38
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• pp.1-10
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• 1979

An inclusion forming virus isolated from a fan webworm, Hyphantria cunea, in 1975 was identified as a nuclear polyhedrosis virus. With the virus isolated in Korea, it was considered that the virus would be one of the valuable microorganism in microbial control. In this connection, 1) the shape and size of the virus for identification, 2) susceptibility of the various instar larvae to the virus, 3) the effects of storage condition on the pathogenicity and the cross infection of the virus to the larvae of Bombyx mori were examined. The results are summarized as follows; 1. The polyhedron was tetrahedron or hexahedron of $2\mu$ in size and the rod-shaped virus particles consisting of $2\~14$ rods in a bundle were $330m{\mu}\times35m{\mu}$ in size. 2. The hexagonal nuclear polyhedra were found only in the nucleus of the midgut cells but were variable in size. 3. The $LD_{50}$ values for the various instar larvae of H. cunea were $8.377\times10^4\;PIBs/ml$ for the second, $4.974\times10^5\;PIBs/ml$ for the fifth instar larvae. The $LT_{50}values$ for $10^6\;PIBs/ml$ were 9.6 days for the second, 11.5 days for the third, 12.0 days for the fourth and 17 days for the fifth instar larvae. 4. The susceptibility of H. cunea to the nuclear polyhedrosis virus was greater in the first generation than in the second generation. 5. The effect of the storage conditions on the pathogenicity of the nuclear polyhedra was less in refrigerator $(5^{\circ}C)$ and in freezing $(-80^{\circ}C)$ than in room temperature $(18.5^{\circ}C)$, especially as air-dried polyhedra than as suspension. The pathogenicity of the polyhedra seemed to decrease by sunlight during storage as cadavers, since rather greater decrease in pathogenicity was found in sunny condition than in shady condition. 6. The effective spray concentration was $6.4\times10^7\;PIBs/ml$ in the field and its $LT_50$ values for the third and the fifth instar larvae were 4.8 days and 14.2 days, respectively. 7. No cross infections were found in the nuclear polyhedrosis virus between H. cunea and B. mori. larvae.

• Tuberculosis and Respiratory Diseases
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• v.57 no.3
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• pp.265-272
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• 2004

Background : RASSF1A, which is one of tumor suppressor genes, is frequently inactivated by hypermethylation of the promoter region in a variety of human cancers, including lung cancer. This study was performed to investigate the association between RASSF1A methylation and the clinicopathological factors in patients with squamous cell carcinoma of the lung. Methods : Eighty-one samples from the patients with squamous cell carcinoma of lung were examined. The promoter methyation of RASSF1A was analyzed by methylation specific PCR and sequencing. Statistical analysis was made to examine the association between RASSF1A methylation and the clinicopathological parameters. Results : RASSF1A methylation was observed in 37.0 % (30 of 81) of the patients with squamous cell carcinoma of the lung. RASSF1A methylation was found to be associated with cellular differentiation(p=0.0097) and the overall survival(p=0.0635). However, there was no association between RASSF1A methylation and the other clinicopathological parameters, such as the pathological TNM stage, the recurrence rate, lymph node invasion and the amount of cigarettes smoked. Conclusion : RASSF1A methylation might be associated with a poor prognosis in patients with squamous carcinoma of the lung. A larger scale study is needed.

• The Journal of Engineering Research
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• v.3 no.1
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• pp.189-197
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• 1998

Hyeroxyapatite(HAp) which has good biocompatibility was made by Wet Chemical Process. The surface of Ti-6Al-4V, coated with HAp by lon Beam Assisted Deposition (IBAD), was treated with 5ppm, 10ppm, 20ppm, and 100ppm of $AgNO_3$ solution. In this Ag impregnation process, $Ca^{2+}$ of HAp was substituted with $Ag^+$ of $AgNO_3$. In this study, the antimicrobial effect and biocompatibility of Ti-6Al-4V alloy which was coated with Ag-HAp were examined. The antimicrobial test was carried out with two kinds of bacteria(P. Aeruginosa, S. Epidermidis), which are highly infectious in a transplanting operation of implant materials. As a result of the test, it was observed that Ti-6Al-4V alloy which was treated by 20ppm of $AgNO_3$ solution has good biocompatibility. In order to observe the antimicrobial mechanism of $Ag^+$, E. coli which is the most common bacterium was treated by Ag-HAp. Then cell morphology of E. coli was observed by the transmission electron microscope(TEM). The destruction of cell wall and cytoplasm of E. coil were observed. A black spot appeared in the cytoplasm was analyzed by energy dispersive analysis X-ray (EDAX) and it showed a small amount of $Ag^+$. Thus, it was proved that $Ag^+$ destroys bacteria effectively and Ti-6Al-4V alloy which was impregnate with Ag ion show antimicrobial effect on infection bacteria.

• The Journal of Engineering Research
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• v.3 no.1
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• pp.199-205
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• 1998

Cullet Quality Control in auto glass bottle factory is the most important in recent days because of the increasing cost of materials in glass bottle. Since the composition of plate glass cullet is similar, the cullet quality using plate cullet in glass bottle factory is easily controlled. In addition to this, the price of plate glass cullet is so low that the cost reduction can be achieved. If the ratio of plate glass cullet and gush is over 25%, the liquidity of glass water become worse, which is caused by different compositions and viscosity of the components. As a results, Furnace bottom temperature becomes low and glass water becomes inhomogeneous. Thus production efficiency of glass bottle becomes low because of increasing devitrification in Dead Corner part in glass melting furnace. Three experimental methods – (1) increasing melting temperature, (2) using Booster, (3) using bubbler – were performed to increase the furnace bottom temperature and glass water homogeneity. The amounts of plate glass cullet was able to increase up to 90%, 70% and 60% without any devitrification using booster, bubbler and the method of glass melting temperature increase from $1480^{\circ}C$ to $1560^{\circ}C$ respectively. It is not possible to increase the glass melting temperature without the reduction of furnace operation time and the increase of fuel cost. The booster process has disadvantage of much electric energy consumption. Since the bubbler process uses physical convection of melting glass based on compression air, the homogeneity of molten glass is not so good as that of booster process but it can reduce the cost of glass bottle.

• Korean Journal of Health Education and Promotion
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• v.13 no.1
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• pp.72-89
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• 1996

The oral health status and practices related to oral health among 44-54-year-, 55-64-year- and 65-year-old needy residents were assessed. The subjects were the residents at the Unbong Permanent Rental Apartment, Bansong-dong, Haeundae-gu. Pusan, Korea. An oral epidemiological survey was undertaken to determine the status of dental caries and periodontal health. Periodontal health were analyzed by the tool of CPITN (Community Periodontal Index of Treatment Needs). A questionnaire was used to interview for the practices of toothbrushing. The numbers of subjects were 192 for the interview on toothbrushing, 228 for the survey of dental status and 208 for the survey of periodontal status. The major results were as follows: 1. Toothbrushing frequencies per day were 1.9 among 44-54-year-, 1.7 among 55-64-year- and 1.7 among 65+-year-subjects. Percentages of after-meal-toothbrushings among total brushing frequencies per day were 73.7% among 44-54-year-, 70.6% among 55-64-year- and 76.5% among 65+-year-subjects. 2. DMFT indices were 15.5 among 44-54-year-, 16.4 among 55-64-year- and 26.6 among 65-year-subjects. Decayed teeth component of DMF teeth were 23.9% among 44-54-year-, 11.6% among 55-64-year- and 62.8% among 65+-year-subjects. Missed teeth component of DMF teeth were 55.59% among 44-54-year-, 62.8% among 55-64-year- and 77.4% among 65+-year-subjects. Filled teeth component of DMF teeth were 20.0% among 44-54-year-, 25.0% among 55-64-year- and 10.9% among 65+-year-subjects. 3. Sound permanent teeth were 16.4 among 44-54-year-, 15.6 among 55-64-year- and 5.4 among 65+-year-subjects. Present permanent teeth were 23.7 among 44-54-year-, 21.6 among 55-64-year- and 10.9 among 65-year-subjects. 4. Subjects who needed professional oral prophylaxis were 75.0% among 44-54-year-, 83.3% among 55-64-year-and 76.9% among 65-year-subjects. Subjects who needed complex periodontal treatments were 16.7% among 44-54-year-, 13.3% among 55-64-year- and 15.4% among 65+-year-subjects. 5. Sextants which needed professional oral prophylaxis were 59.3% among 44-54-year-, 71.5% among 55-64-year- and 71.5% among 65+-year-subjects. Sextants which needed complex periodontal treatments were 5.6% among 44-54-year-, 4.1% among 55-64-year- and 5.7% among 65+-year-subjects. 6. Systematic comprehensive oral health care services should be developed for old needy residents in urban area.

• Clinical and Experimental Pediatrics
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• v.49 no.7
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• pp.757-762
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• 2006

Purpose : Pneumonia is one of the most common infections in children who visit emergency departments(ED), but standard clinical guidelines for children with pneumonia in Korea have not been studied. This study was performed to collect and evaluate a data-base of children with pneumonia for establishing clinical guidelines in ED. Methods : This study reviewed 304 children who were diagnosed and treated for pneumonia in the ED at one tertiary hospital between January 2003 and December 2003 retrospectively by reviewing the charts and analyzing the clinical characteristics, laboratory findings, and radiologic findings between an admission group and a discharge group. Results : The 2 year-5 year age group was the top of age distribution and the peak incidence of monthly distribution was December. Two hundred forty seven(81.3 percent) children were hospitalized(admission group), and the mean length of hospitalization was $7.24{\pm}3.24$ days. The most common indications of admission were fever, tachypnea and an age of less than three months. There was statistical differences in the outpatient department follow-up between the two groups(85.8 percent in admission group vs 35.1 percent in discharge group). Conclusion : More prospective studies are needed to establish clinical standard guidelines for children with pneumonia. This will be helpful in ED management and will aid the prevention of pneumonia.

• Journal of the Korean Geographical Society
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• v.31 no.3
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• pp.577-592
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• 1996

The forming process of poverty region in Taegu and the feature of its spatial distribution which are reviewed hitherto can be summarized like this. 1) In the froming porcess of poverty region in Taegu, during the soverignty of Japanese Empire petty farmers became tenantry by the colonial agricultural policy of Japanes Empire and some of those came into the city and g\became urban poor class. They generally lived in poor houses or dugouts in the city, and 6.6$\circ$ of poor house and dugouts of the whole country were in Taegu and 4.9$\circ of the popolatio in Taegu resided there. During the period of disorder, because of the historic accidents, such as the restoration of independence and Korean War, the returnees from aboad and refugees converged into the big city so that those who need the country's relief stood out as new poor class. They generally made their dwellings with tents and straw-bags on vacant grounds in suburbs living form hand to mouth and shaped the poor houses area, so-clalled "Liberated Village". During the developing period, the number of those who need aid gradually decreased, but the problem of poor people by the city-concentration of the poeple who shifted from agricultrual jobs by economic development came to the front. They mostly lived in squatter area forming large poor class area, and generally located near the center of Taegu consisiting of West. South. East Ward. 2) Reviewing the the feature of spatial distribution, the proportion of poor class are highest within 1~2km from the center of the city and also high within 2~3km form the center and suburbs. The poor class area in the center of the city are mostly cleared and removed area and in suburbs by the construction of permanently leased, and leased apartments large grouped poor class areas are forming. In Taegu, 16 low-income class group residence areas and residential environement improving areas are dispersed so that they came under the so-called poor class area. But by the improvement of dewelling environment and living the poor people who lived in groups dispersed or bettered their living for themselves, so the poverty area is greatly chaning into average-levelled residence area, and on the other hand, large poor people's apartment complexes are being constructed in suburbs. 3) Up to now, the distribution of poverty area could be limited its scale to generally the area within 1~3km because the poverty region which had been in suburbs relatively came near the center of the city by the rapid urbanization and poor people preferred that area because of the living convenience facilities as well as the transportation facilities and job-hunting being near the center of the city. But now poor people's apartment complex is being constructed regardless of their zone of job sites, so the low proportion of occupation is pointed as a new problem.

• Journal of Preventive Medicine and Public Health
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• v.28 no.1 s.49
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• pp.59-72
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• 1995

This study was carried out to analyze the food intake and associated factors of the urban poor elderly by comparing poor district, Unbong rental apartment in Bansong 2 dong with other areas in Pusan. 135 elderlies(men 36, women 99) in Unbong rental apartment, 136 elderlies(men 45, women 91) in the other areas were investigated during the period of March to August in 1994. The assumption that the study area represented poor district was satisfied because the age and sex distribution was not significantly different, and the income of the study area was significantly lower than that of the control area. The variables of hospitalized in previous 12 month, gastrointestinal problem, alcohol drinking, cigarette smoking did not differ significantly. But the variables of chronic disease, take medicine, perceived health, vitamin supplement differed significantly between two groups. Therefore some factors associated with health state in the study area are worse than those of the control area. At most of all variables, nutrients intake of the study area did not reach the recommended dietary allowances(RDA) for Koreans, and that nutrient intakes of the study area were significantly lower than those of the control area. The hypothesis of this study that nutrient status depends on economical status was proved. As for the score of nutritional knowledge, the study area was significantly lower than the control area. But as for the score of nutritional behavior, two areas were not significantly different. The latter is counter result of our hypothesis, owing to the effect of the confounding factors including education etc. As for the correlation of variables, not only economic status and educational level, but the score of nutritional knowledge effects strongly on nutrient status in the study area, the poor district. Therefore, adequate nutritional education to the elderly in e poor district should be considered.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.1
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• pp.29-34
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• 2015

Citrullinemia type1 is an autosomal recessive disorder of the urea cycle characterized by neonatal or late onset of hyperammonemia caused by a deficiency of the enzyme argininosuccinate synthetase (ASS). An ASS1 deficiency demonstrates fatal clinical manifestations that are characterized by the neonatal metabolic coma and early death when untreated. It causes a broad spectrum of effects, ranging from a mild disorder to a severe mental retardation, epilepsy, neurologic deficits. An acute neonatal form is the most common. Infants are normal at birth followed by an acute illness characterized by vomiting, lethargy, seizures and coma. These medical problems are life-threatening in many cases. A later onset form is less frequent and may be milder than the neonatal form. This later-onset form is associated with severe headaches, visual dysfunction, motor dysfunction, and lack of energy. Citrullinemia type1 is caused by mutations in the ASS1 gene located on chromosome 9q34.1 that encodes argininosuccinate synthetase, the third enzyme of the urea cycle catalyzing the formation of argininosuccinic acid from citrulline and aspartic acid. The enzyme is distributed in tissues including liver and fibroblasts. This mutation leads to hyperammonemia, arginine deficiency and elevated citrulline level. In the urea cycle, argininosuccinate synthetase catalyses the conversion of citrulline and aspartate to argininosuccinate.. Here, we describe a female newborn patient with lethargy, rigidity and hyperammonemia who was diagnosed as citrullinemia type1 with a c.[421-2A>G], c.[1128-6_1188dup] mutation.

• Land and Housing Review
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• v.2 no.1
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• pp.35-46
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• 2011

This paper aims at examining the indices and their weights for the evaluation of local government to allocate reconstruction charge and reviewing the availability of them simulating local governments' evaluation. There has been no specific evaluation criteria existed, while central government has to allocate the reconstruction charge to local governments by the provision 3 of Restitution of Housing Reconstruction Gains Act. The results as follows : According to a survey on evaluation indices weight and AHP analysis, the weight of 'the housing welfare improve effort' is the highest with 25.1% among 5 upper-classification indices. Following this, each weight of 'housing welfare conditions(22.7%)', 'housing SOC establishment(22.5%)', 'the achievement and planning on reconstruction charge use(15.8%)', and 'housing sector achievement such as Bogeumjari(13.9%)' are ranked. Meanwhile, Among 16 lower-classification indices, 'the rate of minimum housing standard households(11.5%)', 'public rental housing supply(8.9%)', 'reconstruction charge use achievement(8.3%)', 'reconstruction charge use planning submit(7.5%)', and 'rate of water and sewage(6.3%)' hold high rank. The analysis results show the weight of 'housing sector achievement such as Bogeumjari' on the existing provisions should be decreased(30%${\rightarrow}$13.9%) as others' weight has to be slightly increased. According to the result of the simulation, Jeonbuk, Gyeongbuk, Jeonnam, Jeju, Gyeonggi received higher scores in the comprehensive evaluation, while Daejeon, Seoul, Incheon, Daegu and Gwangju, where the housing conditions are relatively good, received lower scores. These results of the analysis correspond with the direction of reconstruction charges allocation and indicate that the evaluation criteria used in this simulation is acceptable.