• Journal of Korean Medicine for Obesity Research
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• v.18 no.2
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• pp.57-63
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• 2018

Objectives: Metabolic syndrome is defined by a cluster of major cardiovascular risk factors: obesity, insulin resistance, dyslipidemia, and arterial hypertension. Several members of a large family of nonselective cation entry channels, e.g., transient receptor potential vanilloid 4 (TRPV4) channels have been associated with the development of dyslipidemia and hypertension. The purpose of this study was to investigate the effects of Leejung-tang (Lizhong-tang), Rikkunshito, and Bojungikgi-tang (Buzhongyiqi-tang) on TRPV4 channel. Methods: Human embryonic kidney 293 cells stably transfected with the TRPV4 expression vectors were maintained in Dulbecco's modified Eagle's medium supplemented with 10% fetal bovine serum, 1% penicillin/streptomycin, $5{\mu}g/mL$ blasticidin, and 0.4 mg/mL zeocin in a humidified 20% $O_2/10%$ $CO_2$ atmosphere at $37^{\circ}C$. Whole-cell patch clamp recordings were obtained using an Axopatch 700B amplifier and pClamp v.10.4 software (Molecular Devices, San Jose, CA, USA), and signals were digitalized at 5 kHz using Digidata 1422A. Results: Leejung-tang and Rikkunshito (10, 30 and 50 mg/mL) had no effects on the TRPV4 whole-cell currents at dose dependent manner. However, Bojungikgi-tang (10, 30, and 50 mg/mL) inhibited the TRPV4 whole-cell currents in a dose dependent manner and the half maximal inhibitory concentration (IC50) of Bojungikgi-tang was 18.2 mg/mL. Conclusions: These results suggest that Bojungikgi-tang plays an important roles to inhibit the TRPV4 channel, suggesting that Bojungikgi-tang is considered one of the candidate agents for the treatment of metabolic syndrome such as dyslipidemia and hypertension.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.31 no.4
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• pp.174-181
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• 2021

Lightweight geopolymers were fabricated by using IGCC (integrated gasification combined cycle) slag and Si sludge which are classified as general wastes (recyclable resources). Three curing methods were tried to investigate the changes in compressive strength and density according to the curing method and immersion time. Immersion period was tried up to 21 days to observe long-term performance in water. Compressive strength of the specimens cured in oven decreased abruptly with an increase in immersion time. Compressive strength of the specimen cured in autoclave was low after 3 and 7 day immersion; however, increased rapidly after 21 day immersion. On the contrary, compressive strength of the specimen cured in autoclave and oven was high but substantially decreased after 21 day immersion. Conclusively, it was speculated that oven curing is effective for the compressive strength development at early age; however, autoclave curing is more desirable for the long-term performance in water.

• The Journal of the Convergence on Culture Technology
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• v.8 no.4
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• pp.277-287
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• 2022

Recent trends in sharing online video contents show that vlogging on everyday life can cause meaningful changes in viewers' perception of mediated characters and their own lifestyles. We explored that flourishing everyday life video contents online are intertwined with viewers' psychological engagement such as empathy and social presence, let alone self-enhancing motivations such as self-reflection and psychological empowerment. Survey analysis results suggest that between contents types of vlog (everyday life vs. in-depth information), watching in-depth information videos significantly affected viewers' psychological engagement and self-enhancing motivations. Compared to celebrity's online videos, daily videos starring laypeople showed significantly positive impacts on viewers' engagement such as empathy, social presence, and self-enhancement such as self-reflection, psychological empowerment.

• The Journal of Pediatrics of Korean Medicine
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• v.37 no.4
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• pp.34-52
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• 2023

Objective This study aimed to evaluate the effect of herbal medicines on transient hip synovitis (TSH) in children. Methods We searched 10 Korean, English, Japanese, and Chinese databases for studies published up to September 19, 2023. Randomized controlled trials (RCTs) evaluating the effect of herbal medicines on TSH levels in children were included. The Cochrane risk of bias was used to evaluate the quality of the studies. A meta-analysis was conducted according to outcome measurements, such as total effective rate (TER), visual analog score (VAS), time to pain relief, and hip joint mobility disorder disappearance time, using the Review Manager website. Results Eleven RCTs were included in this study. TER in the treatment group was significantly higher than in the control group. The duration of pain relief was significantly shorter in the treatment group than in the control group. The VAS score of the treatment group was significantly lower than that of the control group, although the statistical heterogeneity was substantial. The hip joint mobility disorder disappeared in the treatment group treated with external therapy, which was significantly shorter than in the control group. Regarding safety, two of the 11 studies reported that there were no adverse events. Conclusions Herbal medicines are effective in the treatment of TSH in children. However, the safety of herbal medicines should be carefully considered due to the lack of data.

• Clinical and Experimental Pediatrics
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• v.48 no.3
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• pp.306-309
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• 2005

Purpose : The aim of study is to investigate the clinical manifestations and the etiology of markedly-elevated serum alkaline phosphatase(ALP) levels in children without accompanying liver or bone disease. Methods : The serum ALP and other biochemical laboratory data of 4,989 patients attending the pediatric department of Ewha Womans University Mokdong Hospital between January 2002 to December 2002 were studied. The subjects' ages ranged from 4 months to 14 years. Among them, serum ALP levels were markedly elevated over 1,000 IU/L in 114 children. Among those 114 children, 97 children without liver or bone disease were reviewed retrospectively. Results : Of the 114 children with serum ALP activity of over 1,000 IU/L, 97(85.8 percent) children had neither liver or bone disease. The average ALP activity level was $1,539{\pm}948IU/L$. The male : female ratio was 1 : 0.7. Forty-four children(45.3 percent) were between 4 months to 1-year-old, 19 children(19.3 percent) were between 1- to 2-year-old. We observed a seasonal clustering of cases in during October with 10 cases(10.2 percent) and in during December with 11 cases(11.3 percent). The most common clinical presentation was respiratory tract infection in 25 cases(26.9 percent), and acute gastroenteritis in 17 cases(17.5 percent). Forty-four cases had follow-up ALP activity level, 1 month later and the activity decreased under 1,000 IU/L in 37 cases(84 percent). Conclusion : Hyperphosphatasemia is a benign and transient phenomenon. If there are no clinical and laboratory abnormalities of liver and bone, we suggest monitoring monitor the high serum ALP level 1 month later. If decreased, it seems that it is not necessary for specific examinations to exclude other diseases of malignant condition.

• Journal of the korean academy of Pediatric Dentistry
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• v.35 no.2
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• pp.205-215
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• 2008

The purpose of this study is to evaluate at which stage of tooth germ would develop into normal calcification and hence to increase the success rate of transplantation. Therefore, tooth germs on the 15th, 17th embryonic day and the 3rd day of birth were separated for allotransplantation into maxilla of adult rat of 11 weeks. Calcification processes were analyzed radiographically and histopathologically at 4 weeks and 8 weeks after allotransplantation. The results are as follows: 1. Allotransplanted tooth germ at 4 weeks and 8 weeks showed delayed calcification compared to that of normal odontogenesis. 2. At 4 weeks, abnormal calcified tissue, such as odontoma and ankylosis of osteodentin with surrounding alveolar bone were observed. 3. At 8 weeks, allotransplanted tooth germs of the 15th and 17th embryonic day showed calcification and osteodentin surrounded by periodontal ligament. 4. At 8 weeks, allotransplanted tooth germs of the 3rd day of birth showed calcification composed of cementum and osteodentin. In this study, we observed small sized and amorphous calcified tissue from allotropic allotransplantation of tooth germs. Since these calcified tissue were underdeveloped and shaped irregularly, for calcification into normal tooth form, further study needs consideration about the reduction of surgical trauma, developmental stage of transplanted tooth germ, blood supply from recipient site, fixation method in transplanted site and period of transplantation.

• The Korean Journal of Financial Management
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• v.17 no.2
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• pp.175-209
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• 2000

본 연구는 프로그램매매가 주가지수 선물시장 및 현물 주식시장의 수익률 변동성에 미치는 효과에 대해서 일중 수익률 및 프로그램매매자료를 이용하여 분석을 시도하였다. 실증분석을 통해서 관찰된 결과를 살펴보면 대부분 선진국 시장에서 보고된 결과와 일치하였다. 우선 프로그램매매가 증가할수록 현물 주식시장에서의 변동성은 증대하는 것으로 나타났으나 선물시장에서는 그러한 일관성 있는 관계를 발견하지 못하였다. 프로그램매매 발동 직후 선물 및 현물시장의 수익률은 반전현상을 나타냈으며 특히 현물시장의 가격변화가 선물시장에 비해서 큰 것으로 관찰되었다. 그러나 이러한 선물시장과 현물시장에 있어서의 가격반전 현상이 시장 유동성에 미치는 경제적 영향은 선물만기일과 같이 특정시간대에 프로그램매매가 집중되지 않는 한 경미한 것으로 판단되었다. 프로그램매매 특히 차익거래는 선물 가격과 현물 가격간의 균형 관계가 일시적인 수급상황에 따라 이발될 경우 이를 다시 균형 상태로 회복시켜 줌으로써 시장의 효율성을 증대시키는 주요한 연결통로로서의 역할을 수행한다. 특히 두 시장간의 균형 상태는 선물 시장보다는 현물 주식시장에서의 활발한 매매 활동을 통하여 이루어짐을 알 수 있었다. 결론적으로 국내시장에서 차익거래는 시장의 위험을 증대시키는 부정적인 측면보다는 시장의 효율성을 증진시키는 긍정적인 순기능이 많은 것으로 관찰되었다.

• Proceedings of the Korean Information Science Society Conference
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• 2006.06b
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• pp.52-54
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• 2006

유비쿼터스와 유무선 기술의 발전으로 최근들어 각 개인과 그를 둘러싼 환경으로부터 지속적으로 많은 데이터를 수집할 수 있게 되었다. 상황인지 기법들을 활용하면, 수집된 데이터께서 각 개인의 경험을 요약할 수 있는데, 요약된 경험 정보는 해당 개인의 기억 회상에 도움을 줄 뿐 아니라, 다른 사람들과의 상호작용을 증대시키는 데도 유용하게 사용된다. 본 논문에서는 모바일 상에서 수집된 특이성 정보를 바탕으로 사용자의 프로필을 고려하여 개인의 일과를 만화의 형태로 표현하는 방법을 제안한다 특이성 정보는 휴대폰 로그로부터 상황인식 기법을 통해 추론된 것으로 사용자의 행동 및 감정 정보를 나타낸다. 추론된 사용자의 행동 및 감정 정보들과 미리 입력된 사용자 프로필을 바탕으로 본 논문에서는 배경과 캐릭 터 만화 이미지들을 의미적 유사도를 사용하여 합성한다. 또한, 생성된 만화 이미지들에서 동적으로 스토리 스트림을 구성하여 만화 내용의 일관성을 유지한다. 제안하는 만화 생성 방법을 평가하기 위하여 특이성 시나리오를 바탕으로 만화를 합성하여 생성된 만화의 다양성과 일관성을 평가하였다.

• Journal of the Institute of Electronics Engineers of Korea SC
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• v.43 no.5 s.311
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• pp.89-100
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• 2006

The carotid intima-media thickness (IMT) is very important, because the severity of it is an independent predictor of transient cerebral ischemia, stroke, and coronary events such as myocardial infarction. The conventional image processing to measure the IMT has not been satisfactory, because the methods have relied on the manual section drawing and a regional segmentation by differential estimation. We propose a new image processing technology effective to extract features from the carotid artery image whose pixels have the directional vector properties with composed color distribution. The technique we presented here is not by differential variation but by verification of the layer properties of carotid artery image. Iterated vertical and horizontal analysis and segmentation of the IMT image show the vector characteristics. This new technique makes it possible to cluster the layers statistically, and to classify mathematical correlation between regions and resulting in correct measurements of thickness and its variation. The advantages and effectiveness of this approach are applicable to region process and character extraction of such a vector image.

• Applied Biological Chemistry
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• v.50 no.4
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• pp.281-286
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• 2007

The effects of green tea powder (GTP) on kimchi quality were evaluated by investigating acid production, growth of lactic acid bacteria, sensory properties, and several volatile odor components of GTP-added kimchi. The concentrations of GTE added to kimchi were 0.2, 0.4, 0.6 and 1.2% (w/w) of salted Chinese cabbage. The pH of kimchi with higher amounts of added GTP increased with ripening. The acidity of unripened kimchi or kimchi ripened for one day generally increased with the addition of GTP, while that of kimchi ripened for two or three days generally decreased with the addition of GTP. Addition of GTP had no significant effect on the lactic acid bacterial count of kimchi. Scores of overall acceptability, taste and odor of 0.2 or 0.4% GTP-added kimchi were higher than those of other samples, whereas scores of color decreased with increasing amount of GTP added to kimchi. Texture of kimchi added with higher amounts of GTP and ripened for two or three days resulted in lower score than the reference sample. Diallyl sulfide and methyl trisulfide were newly produced with the ripening of kimchi, and the amounts of some volatile odor components in kimchi were changed during ripening.