• Title/Summary/Keyword: 이차분석

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Optimization for Hot Water Extraction Process of Cordyceps militaris using Response Surface Methodology (반응표면분석법에 의한 동충하초 열수추출공정의 최적화)

  • 윤광섭;정용진;이기동;신승렬;구재관
    • Food Science and Preservation
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    • v.9 no.2
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    • pp.184-188
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    • 2002
  • This study was conducted to optimize hot water extraction process of cordyceps militaris for development beverage. Optimal condition for hot water extraction was investigated with changes in extraction concentration and temperature by response surface methodology. The content of soluble solid was effected with concentration. The efficiency of extraction for turbidity, total sugar, reducing sugar and protein increased with low concentration. The response variables had significant with concentration and the established polynomial model was suitable (p>0.05) model by lack-of-fit analysis. Optimal extraction conditions as the limited renditions of 2.0∼2.4% extractable solids, 1.5∼2.0% brix, l14∼120 $\mu\textrm{g}$/g total sugar, 10.5∼11.0 $\mu\textrm{g}$/g reducing sugar and 110∼l15 $\mu\textrm{g}$/g protein were 95∼100$\^{C}$ and 4.0∼4.1% of concentration.

Behavior Analysis of Particle Crushing about Sabkha Layer under Hydrotest (Sabkha층의 Hydrotest 시 입자파쇄 거동분석)

  • Kim, Seokju;Han, Heuisoo
    • Journal of the Korean GEO-environmental Society
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    • v.14 no.9
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    • pp.57-65
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    • 2013
  • Carbonate sands can be crushed under low confining pressure to achieve high compressibility. So particle crushing has significant influence on characteristics of strength and deformation. Trial embankment and hydrotest are conducted on Sabkha layer, consisting of carbonate sand to build tank structure. In this paper the settlement behavior was analyzed from each test. Particle crushing happened from 80 to 170kPa stress under compression test, and calcium was detected from chemical test. The test result came out Sabkha soil was very weak and easy to be crushing. About trial embankment test, particle crushing was not happen, and then extinction of pore water pressure and settlements were finished just during 2 days. On the other hand, the long-term settlement was happened in hydrotest. So the two test results did not correspond to each other. If loading stress is higher than yielding stress, instant settlement and secondary compression settlement are happened as a result of the particle crushing.

A Study on Convergence Factors Related to Cardiovascular Disease in Korean Elderly (노인의 심뇌혈관질환 관련요인의 융복합적 규명)

  • Park, Jeeyeon
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.1
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    • pp.215-221
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    • 2020
  • The purpose of this study was to investigate convergence factors associated with cardiovascular disease in Korean elderly and use them as basic data for developing a customized health program for elderly. This was a secondary data analysis study using the 2017 National Health and Nutrition Survey and the study subjects included 1,617 individuals aged 65 and over. Regression analysis showed that perceived health status, walking practice and hypercholesterolemia were related to cardiovascular disease in elderly. In case of perceived health status, the incidence of cardiovascular disease was higher in 'good', 'fair', 'poor', and 'very poor' compared to 'very good'. Also, the incidence of cardiovascular disease was higher in the 'No' than in rhe 'Yes' of the walking practice, and higher in the case of elderly with the hypercholesterolemia. Based on the results, it is necessary to develop an active prevention nursing intervention program considering the underlying disease of the elderly.

Inhibitory Melanogenesis of Bambusae caulis in Taeniam and Profiling of Related Proteins (죽여의 멜라닌 생성 억제 효과 및 관련 단백질 동향 분석)

  • Lee, Chung-Hyun;Kim, Sang-Bum;Byun, Sang-Yo
    • KSBB Journal
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    • v.25 no.5
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    • pp.478-482
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    • 2010
  • Inhibitory melanogenesis by Bambusae caulis in Teaniam (Phyllostaachys nigra var. henonis Stapf) was studied. Tyrosinase inhibition activities were evaluated with six different extracts. Among them the extract with methanol showed the highest tyrosinase activity inhibition. MTT assay with B16 melanoma showed that the extract was not toxic up to the concentration of 50 ppm. The melanogenesis was clearly inhibited by the extract when it was examined by the melanin content assay in the cell. When the extract was dosed as 10 ppm, the melanogenesis was reduced to 68% in culture medium and 74% in the cell. By the proteome analysis with 2-D electrophoresis, 171 protein spots were found in the control gel and 282 spots were detected in the sample gel. Among 120 spot proteins matched, 12 spots were identified as proteins involved in the melanogenesis mechanism.

Mining the Secondary and Tertiary Structures Elements of RNA from the Structure Data of PDB (RNA의 이차 구조 요소 및 삼차 구조 요소를 추출하기 위한 PDB 구조 데이터 마이닝)

  • 임대호;한경숙
    • Proceedings of the Korean Information Science Society Conference
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    • 2003.10b
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    • pp.826-828
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    • 2003
  • 이제까지 Protein이나 RNA와 같은 분자의 구조는, 대부분 X-ray crystallography나 Nuclear Magnetic Resonance (NMR) 방법을 통해 분석이 이루어 졌다. 이 방법들은 실제 분자를 직접 원자레벨에서 분석하는 방법으로, 분자를 구성하는 모든 원자의 3차원 좌표 정보를 얻어 낼 수 있다. 원자의 3차원 좌표 정보는 분자의 전체적인 모양과 구조를 이해하는데 유용한 정보이다. 하지만, 분자의 구조를 좀 더 완벽히 이해하기 위해서는 원자 레벨의 좌표 정보 보다는 좀 더 높은 차원에서의 구조 정보가 필요하다. 특히 분자의 구조를 예측하거나, 분자들 사이에 결합 관계를 예측하기 위해서는, 원자 레벨의 정보만으로는 필요한 모든 정보를 얻을 수 없다. 이러한 경우, 분자의 2차원 또는 3차원 구조 요소 (structural elements)가 더욱 좋은 정보를 제공해 줄 수 있다. Protein 분자의 경우. 이미 3차원 좌표 정보를 이용해서, 2차원 구조 요소를 알아내는 자동화된 방법이 알려져 있다. 그러나 RNA의 경우 protein에 비해 알려진 결정 구조가 적기 때문에. 아직까지 2차원 구조 요소나 3차원 구조 요소를 알아내는 자동화된 방법이 알려져 있지 않다. 따라서, 이제까지는 RNA의 구조 요소를 알아내기 위해, 사람이 직접 RNA분자의 3차원 좌표 정보를 분석함으로써 많은 시간과 노력이 필요했다. 이 때문에, 우리는 RNA의 원자들의 3차원 좌표 정보를 이용해서, 2차원 구조요소와 3차원 구조 요소 정보를 자동화된 방법으로 밝혀내는 알고리즘을 개발하였다. 우리는 분자를 구성하고 있는 원자들의 3차원 좌표 정보를 Protein data bank (PDB)에서 가져왔다. 우리의 알고리즘은 PDB file형태의 데이터라면 protein-RNA 복합체나 RNA 분자 모두에서 RNA의 2차원 구조 요소나 3차원 구조 요소를 얻어낼 수 있다. 우리의 연구는 RNA의 원자레벨의 3차원 좌표 정보를 이용해서 RNA의 구조 요소를 뽑아내는 첫 번째 시도로, 우리의 알고리즘을 통해 얻어진 구조 정보는 RNA의 구조 예측 연구나. protein-RNA complex의 결합 예측 연구에 많은 도움을 줄 수 있으리라 기대된다.

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Factors Associated with Intention to Quit Smoking in Male Smokers Who Have Not Tried to Quit Smoking in Seoul : Based on the Theory of Planned Behavior (금연 시도경험이 없는 서울시 남성 흡연자의 금연의도 영향요인: 계획된 행동론에 근거하여)

  • Shin, Eunyoung;Kim, Hyeongsu
    • Journal of Convergence for Information Technology
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    • v.11 no.11
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    • pp.210-218
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    • 2021
  • This study was conducted to provide a basis for developing strategies to improve the intention to quit smoking by identifying the factors affecting the smoking cessation intention of male smokers living in Seoul who have not tried to quit smoking in the past year. The components of the planned behavioral theory were used to identify the influencing factors. The research data were analysed secondary data used in the study performed by the Korea Centers for Disease Control and Prevention in 2020. As a result of the univariate analysis, the factors affecting the smoking cessation intention rate were the average daily smoking amount and the components of the TPB. As a result of multivariate logistic regression analysis, the subjective norm and the perceived behavior control factor among the components of the TPB had statistically significant differences. Therefore, in order to increase the intention to quit smoking, it would be effective to use strategies that strengthen the strong recommendations from significant others and the smoker's self control.

A study on relationship between Physical activity, Diet pattern and Mental health of Korean elderly (한국노인의 신체활동 및 식생활과 정신건강 관련성에 대한 연구)

  • Yun, Haesun
    • Journal of the Korea Convergence Society
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    • v.9 no.12
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    • pp.313-319
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    • 2018
  • The purpose of this study was to investigate the relationship between physical activity, diet and mental health of elderly and to use the study as basic data for a program development for elderly. This was a secondary data analysis study using the 2015 National Health and Nutrition Survey and the study subjects included 1,484 individuals aged 65 and over. The results showed that depression and stress perception in young-old were higher than old-old's and the suicidal ideation rate of old-old was higher than young-old's. In case of eating patterns, 'poor eating' in old-old was higher than young old's. Regression analysis showed that middle-intensity physical activity and eating patterns were associated with mental health of the elderly. Based on the results, it is necessary to develop a differentiated nursing intervention program suitable for the elderly by age.

A Study on the Acoustic Analysis Method of the External Ear Canal Using DICOM Images (DICOM 영상을 이용한 외이도 음향해석 방법에 관한 연구)

  • Kim, Hyeong-Gyun
    • Journal of the Korea Convergence Society
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    • v.10 no.3
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    • pp.73-79
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    • 2019
  • This study simulated external ear canal modeling with different external ear canal lengths, vertical flexion angles, and inner/outer diameter ratios using digital imaging and communications in medicine(DICOM) of the head temporal region and measured the acoustic sensitivity. The experiment was performed by increasing the audible frequency for humans by 200 Hz and expressing the frequency constantly transmitted at 1 Pa as the eardrum acoustic volume and presented the measurements by linear and quadratic curve regression analysis. The results showed that the longer the external ear canal length and the higher the ratio of the outer/inner diameter, the faster the acoustic response at lower frequencies. The acoustic sensitivity correlation of the meta-model using regression analysis showed a 77% influence by the external ear canal length and 5% by the external/internal diameter ratio, while the vertical flexion angle did not show a significant relationship. This showed that auditory acoustic sensitivity of humans is a factor that reacts faster at a low frequency when the external ear canal length is longer and when the difference between the outer and inner diameter is higher.

Mediating Effect of Job Satisfaction in the Impact of Depression on Life Satisfaction of the Working Elderly (경제활동 노인의 우울이 삶의 만족도에 미치는 영향에 있어 일 만족도의 매개효과)

  • Oh, Yeong-Kyong
    • The Journal of the Korea Contents Association
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    • v.19 no.6
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    • pp.271-280
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    • 2019
  • Purpose: The purpose of this study was to examine the effect of depression and job satisfaction on life satisfaction of the elderly and prove the mediating effect of job satisfaction. Methods: This study is a pathway analysis study using 3060 working elderly. This study was performed as secondary analysis using the data from the 2017 Korean Elderly Examination Survey. Data were analyzed using descriptive statistics, correlation analysis and pathway analysis. Results: Depression, job satisfaction and life satisfaction showed significant correlation. Life satisfaction was directly affected by depression(.38, p=.019) and job satisfaction(.22, p=.009). Job satisfaction was also directly affected by depression(.20, p=.009). Depression was mediated by job satisfaction in affecting to life satisfaction. Conclusion: Depression and job satisfaction affect to life satisfaction of the working elderly and life satisfaction is affected by depression via job satisfaction. It suggests that it needs to provide nursing intervention for job satisfaction for life satisfaction of the working elderly.

Development and importance analysis of evaluation factors for formation of future-oriented rural residential environment: using network analysis and AHP analysis (농촌다운 주거환경 조성을 위한 평가항목 개발 및 중요도 분석 - 네트워크 분석과 AHP 분석 활용 -)

  • Lee, Cha Hee;Lim, Jung Eon;Lee, Sang Moon;Yun, Sang Hun
    • Journal of Korean Society of Rural Planning
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    • v.25 no.2
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    • pp.89-98
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    • 2019
  • The purpose of this study is to develop the evaluation factors for formation of the future - oriented rural residential environment and to derive the importance of this evaluation factors. The main research methods are network analysis using Net-miner, AHP analysis and importance analysis for experts. The main research results are as follows. First, 6 factors for evaluation rural residential environment(environmental-sustainability, communality, self-reliance, aesthetic, enjoyment, settlement), 3 sub-factors of each factors, and key physical facilities(10 for rural center and 28 for rural villages) were derived by literature analysis and network analysis on it. Second, key priority factors that should be considered in physical formation of rural residential environment was deducted by AHP analysis. Improving accessibility of living services in the settlement factor, improvement of garbage collection and wastewater treatment system around the residential area, and ensuring topographic continuity in the environmental-sustainability factor was derived as a priority factors. Third, as a result of evaluation of the importance of physical facilities in the rural residential environment, there was a high demand for cultural welfare facilities in common. However, when compared with the villages where the harmony between the natural environment and the living environment is emphasized, convenience of living and accessibility of transportation were important in the rural center. These results suggest that solving the qualitative conditions as residential environment will help to attract new population. This study will contribute to enhance the qualitative level of the rural residential environment by suggesting strategic priority items when carrying out projects related to the rural residential environment creation in the future.