• Title/Summary/Keyword: 유사성 탐색

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Biological activities of Hovenia dulsis $T_{HUNB}$ (헛개나무의 생리활성 탐색)

  • Lee, Mi-Kyoung;Kim, Young-Kil;An, Sang-Wook;Kim, Min-Hae;Lee, Jin-Ha;Lee, Hyeon-Yong
    • Korean Journal of Medicinal Crop Science
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    • v.7 no.3
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    • pp.185-192
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    • 1999
  • Four different parts of Hovenia dulcis $T_{HUNB}$; fruit, bark, vessel area, fruit coat were extracted with water and ethanol. The ethanol extracts of bark, fruit coat and fruit were fractionized into diethyl ether, chloroform and aqueous partitions. Ethanol extract of fruit coat increased the activity of cathepsin B up to 55 %, which can enhance the alcohol dehydration in the liver. The ethanol extracts was more effective than water extracts against the growth of Hep3B, MCF7. The ethanol extracts of bark (0.5mg/ml) inhibited 90% the growth of MCF7. Each extracts and fractions (0.5mg/ml) did not show considerable cytotoxicity on HEL299. In overall, most of the fractions had similar effects to ethanol extracts; however, diethyl ether and chloroform fractions had higher bioactivity than ethanol extracts, but aqueous fraction.

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Antioxidative Activities of Water Extracts from Different Parts of Taraxacum officinale (민들레의 부위별 열수 추출물의 항산화 활성)

  • Han, Eun-Kyung;Lee, Ji-Young;Jung, Eui-Jin;Jin, Yong-Xie;Chung, Cha-Kwon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.39 no.11
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    • pp.1580-1586
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    • 2010
  • This study was conducted to examine antioxidative and physiological activities of water extracts from different parts (flower, leaf, root, and the whole plant) of Taraxacum officinale. The water extracts from different parts were measured to obtain total flavonoids content, total polyphenol content, electron donating ability, SOD-like activity, nitrite-scavenging ability and tyrosinase inhibition effects. Total flavonoids and total polyphenol contents in flower extract were 32.91 mg/g and 49.31 mg/g, respectively, which were much higher than those of any other parts. The electron donating abilities of flower, leaf, the whole plant, and root extracts were 87.07%, 87.66%, 81.06% and 66.20%, respectively at a concentration of 1 mg/mL. The activities increased in a dose-dependent manner. The SOD-like activity of water extracts from different parts showed 9.07~10.97% at a concentration of 1 mg/mL. The nitrite-scavenging abilities of flower and leaf extracts measured at pH 1.2 were 36.34% and 38.16%, respectively at a concentration of 1 mg/mL. Tyrosinase inhibition activity of the leaf extract at a concentration of 1 mg/mL was the highest (34.19%) and that of the whole plant and root extracts was shown to be more than 20%. These results suggest that water extracts from different parts of Taraxacum officinale could be used as an antioxidative functional food source.

Usefulness of Meyerhold's 'Biomechanics' as an Alternative for a Method of Actor Training II - Focused on the Actual Training Program of 'Biomechanics' (배우 훈련 방법의 대안으로서 메이어홀드 '인체역학'의 효용성 II - '인체역학'의 실제 훈련 프로그램을 중심으로)

  • Cho, Han-Jun
    • The Journal of the Korea Contents Association
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    • v.14 no.11
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    • pp.89-101
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    • 2014
  • The 'Biomechanics', which was devised to systematically train actor's material and medium, is evaluated as the first approach to an acting method in earnest with Stanislavsky's 'System'. Especially, due to the psycho-physical features of 'Biomechanics' that helps an actor to master a mechanism of human being such as stimulus, impulse and reaction, it was valued as an alternative for a naturalistic acting method that was excessively focused on the actor's emotional expression. However, the 'Biomechanics' is not utilized with activity in a field of actor training in Korea compared with Stanislavsky's 'The Method of Physical Action' which has a similar starting point as the psycho-physical feature. It is because of a political reason that a study for Meyerhold was officially forbidden in Russia until the mid-twentieth century. It is also because of a limit that incorporeal features of the 'Biomechanics' could not but be explained only by publications, especially translation. In this sense, as part of seeking for a new alternative of acting methods in Korea, this study will explore a possibility of applying the 'Biomechanics' to the actual actor training field through correct understanding of it.

Isolation and Characterization of Actinomycete Strain BK185 Possessing Antifungal Activity against Ginseng Root Rot Pathogens (인삼 뿌리썩음병균에 항균활성이 있는 방선균 BK185의 분리 및 특성)

  • Kim, Byung-Yong;Bae, Mun-Hyung;Ahn, Jae-Hyung;Weon, Hang-Yeon;Kim, Sung-Il;Kim, Wan-Kyu;Oh, Dong-Chan;Song, Jaekyeong
    • The Korean Journal of Pesticide Science
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    • v.18 no.4
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    • pp.396-403
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    • 2014
  • Ginseng (Panax ginseng C. A. Meyer) is an economically valuable pharmaceutical crop in Korea. In order to find promising biocontrol agents for soil-borne fungal pathogens which infect ginseng roots, we have isolated actinomycete, BK185 from soil. The isolate was investigated for the antifungal activity against to ginseng rot pathogens prior to testing genetic and chemical properties. The strain was identified as Streptomyces sp. using phylogenetic analysis based on 16S rRNA gene sequence. The most closely related species was S. sporoclivatus and S. geldanamycininus with high similarities (>99%). The isolate, BK185 showed positive reaction for PCR detection targeting biosynthetic gene clusters of PKS (Type-I polyketide synthase) and NRPS (Non-ribosomal polypeptide synthetase) genes. Major metabolite from the BK185 was analyzed by The LC/MS and identified to geldamycin, which was known to contained broad antibacterial, antifungal or anticancer activities. The results provide evidences that the strain, BK185 can be promising biocontrol agent for ginseng organic farming.

The Research on the Effects of the Transformational Leadership on Organizational Effectiveness: on the Moderating Effects of Personal Thinking Type- (변혁적 리더십이 조직효과성에 미치는 영향에 관한연구 -개인 인지사고 유형의 조절효과를 중심으로-)

  • Lee, Sung-Choon
    • The Journal of the Korea Contents Association
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    • v.17 no.2
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    • pp.337-348
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    • 2017
  • The Army tried to settle the mission command in army command system in 1999 but still not be settled. One of the reason is the absence of practical plans of mission command. The purpose of this study is to find out the moderating effects of personal thinking type to the impact on organizational effectiveness about the impact on organizational effectiveness on sub factors the transformational leadership The main results of this study are as follows. <H1> The charisma and the personal considerations of sub factors of transformational leadership effected positively(+) on the job satisfaction, the charisma effected positively(+) on the organizational commitment. But There was no statistically significant influence on the personal considerations and the effort advocacy <H2> In the result of the moderating effects, in accordance the of a person's each cognitive processing traits is high and low, on the transformational leadership turned out to be a gap in the influence show the difference in organizational effectiveness.on the organizational effectiveness. This results suggest the following. The first. The military group regard highly commandand and discipline. so, the charisma of a superior is that a big impact on organizational effectiveness. The second, For the mission command is to become established in the army, It suggest that need to explore of sub factors of the mission command and need to consider of personal traits with the mission command.

Who is the Busiest in Korea? A Study on Gender Difference in Time Pressure (남녀의 시간압박인식 차이와 관련요인 탐색)

  • Cha, Seung-Eun
    • Korea journal of population studies
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    • v.33 no.1
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    • pp.27-49
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    • 2010
  • The aim of this study was to get answers to following research questions: Who are the busy people in such a speedy society like Korea? How the daily schedules of busy people might look like? What is the priority of activity that appear in their schedules?, And what is the gender difference? The sample of study came form the 2004 Korean Time Diary Data which have been collected by Korean National Statistical Office. The sample consisted of 11,976 married men and women, whose age range from 25-54 (women 49.7% of the sample). Dependent variable was time pressure measured in one item question with 4-likert scale. Socio-demographic factors and the amount of time in work/family role and other relevant activities were considered as well as gender. The results of the study showed us that men perceived more time deficit compared to women. Especially, employed men were the most time poor group, followed by employed women, unemployed women and unemployed men. The results showed that, even though there were similarities in the impact of relevant factors, men's time pressure were tightly linked with their work role and social status, while women's time pressure were responsive to both their role as a mother and as a worker. Nowadays, Korean fathers appear to face new expectation that they need to be involved in family just like mothers do. However, men and women still seems to traverse through different time path, which may create both burden and conflict to either party. Policy implication and detailed suggestions were discussed.

Analysis of Characteristics of Seismic Source and Response Spectrum of Ground Motions from Recent Earthquake near the Backryoung Island (최근 백령도해역 발생지진의 지진원 및 응답스펙트럼 특성 분석)

  • Kim, Jun-Kyoung
    • Geophysics and Geophysical Exploration
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    • v.14 no.4
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    • pp.274-281
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    • 2011
  • We analysed ground motions form Mw 4.3 earthquake around Backryoung Island for the seismic source focal mechanism and horizontal response spectrum. Focal mechanism of the Backryoung Islands area was compared to existing principal stress orientation of the Korean Peninsula and horizontal response spectrum was also compared to those of the US NRC Regulatory Guide (1.60) and the Korean National Building Code. The ground motions of 3 stations, including vertical, radial, and tangential components for each station, were used for grid search method of moment tensor seismic source. The principal stress orientation from this study, ENE-WSW, is consistent fairly well with that of the Korean Peninsula. The horizontal response spectrum using 30 observed ground motions analysed and then were compared to both the seismic design response spectra (Reg Guide 1.60), applied to the domestic nuclear power plants, and the Korean Standard Design Response Spectrum for general structures and buildings (1997). Response spectrum of 30 horizontal ground motions were used for normalization with respect to the peak acceleration value of each ground motion. The results showed that the horizontal response spectrum revealed higher values for frequency bands above 3 Hz than Reg. Guide (1.60). The results were also compared to the Korean Standard Response Spectrum for the 3 different soil types and showed that the vertical response spectra revealed higher values for the frequency bands below 0.8 second than the Korean Standard Response Spectrum (SD soil condition). However, through the qualitative improvements and quantitative enhancement of the observed ground motions, the conservation of horizontal seismic design response spectrum should be considered more significantly for the higher frequency bands.

Antioxidative Activity of Ethanol Extracts from Different Parts of Taraxacum officinale (민들레의 부위별 에탄올 추출물의 항산화 활성)

  • Han, Eun-Kyung;Jung, Eui-Jin;Lee, Ji-Young;Jin, Yong-Xie;Chung, Cha-Kwon
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.40 no.1
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    • pp.56-62
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    • 2011
  • This study was conducted to investigate antioxidative and physiological activities of ethanol extracts from different parts (flower, leaf, root, and the whole plant) of Taraxacum officinale. The ethanol extracts from different parts were measured to examine total flavonoids content, total polyphenol content, elect ron donating ability,superoxide dismutase (SOD)-like activity, nitrite-scavenging ability and tyrosinase inhibition effects. Total flavonoids content in leaf extract (41.66 mg/g) and total polyphenol content in flower extract (71.91 mg/g) were higher than those of other parts. All assays were conducted at concentrations of 0.1, 0.3, 0.5, and 1 mg/mL ethanol extracts. The electron donating abilities of leaf, flower, the whole plant, and root extracts were 92.25%, 88.18%, 84.55% and 83.40%, respectively, at a concentration of 1 mg/mL. The activities were concentration dependent. The SOD-like activity of ethanol extracts from different parts was 8.40~11.20% at a concentration of 1 mg/mL. The nitrite-scavenging abilities of flower and leaf extracts measured at pH 1.2 were 47.37% and 47.18%, respectively, at a concentration of 1 mg/mL, which were higher than those of the whole plant and root extracts. Tyrosinase inhibition activity of the leaf extract at a concentration of 1 mg/mL was the highest (34.22%) and that of the whole plant and root extracts was shown to be more than 20%. These results suggest that ethanol extracts from different parts of Taraxacum officinale could be used as antioxidative functional food sources.

Effects of Scutellaria baicalensis Extracts on Tyrosinase Gene Expression in B16 Melanoma Cells (B16 Melanoma Cell에서 티로시나아제 유전자 발현에 황금(Scutellaria baicalensis) 추출물이 미치는 효과)

  • Cho, Nam-Chul;Bai, Suk;Chin, Jong-Eon
    • The Korean Journal of Food And Nutrition
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    • v.23 no.1
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    • pp.118-123
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    • 2010
  • To estimate the regulatory effects of Scutellaria baicalensis extracts on melanin biosynthesis, we evaluated the regulatory effects of the tyrosinase gene on B16 melanoma cells. The results revealed that methanolic extracts of Scutellaria baicalensis resulted in a high increase in the expression of the tyrosinase gene. Specifically, treatment with extracts at concentrations of $10\;{\mu}g/m{\ell}$ and $100\;{\mu}g/m{\ell}$ resulted in increases in tyrosinase gene expression rates of approximately 231% and 256%, respectively, when compared to the control. Moreover, the solvent fraction layers(methylene chloride, ethyl acetate, butyl alcohol, water) improved the expression of the tyrosinase gene, but to a lesser degree than the methanolic extracts. An MTT assay revealed, that the methanolic extract exhibited very low cytotoxicities at $10\;{\mu}g/m{\ell}$ and $100\;{\mu}g/m{\ell}$. Taken together, the results of this study indicated that the methanolic extracts of Scutellaria baicalensis was a very effective positive regulator of tyrosinase gene expression.

Minimum-Cost Path Finding Algorithm in Real-Time For Computer Generated Force (실시간성을 고려한 가상군 최소비용 길 찾기 알고리즘)

  • Han, Chang-Hee;Min, Young-Hye;Park, Sang-Hyuk;Kim, Jai-Hoon
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.48 no.1
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    • pp.17-25
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    • 2011
  • At the computer games, we can experience a variety of environments using a virtual object. It is similar to that be trained in War-game simulator of the defense. Actual soldiers and a computer-generated virtual group(Computer Generated Force: CGF) in 3-D virtual battlefield environment are training. However, path finding algorithm, one of the techniques of simulation models, to the current level only considers the shortest time path. So, this current level at the special situation of the army in the battlefield for selecting the optimal path is limited. The focus of this paper is to select the least-cost path using the deadline with several different mission conditions(METT+TC). For the only shortest time path algorithm and the least-cost path algorithm using dealine,($d_t$, one of METT+TC elements), Its usefulness is verifying the change of the move spent time(t) for all possible paths and the fighting power of the combat troops(Troops ability, a) through a comparison of the total cost of moves(c(t)). According to the results, when considering the deadline, the proposed algorithm saves about 62.5% of the maximum cost.