• Applied Chemistry for Engineering
• /
• v.21 no.6
• /
• pp.593-602
• /
• 2010

Chitosan as a natural polymer has superior physicochemical properties such as biocompatibility, biodegradability and nontoxicity, but application of chitosan for therapy of cancer and gene related-disease has been limited by poor solubility in aqueous solution. Therefore, low molecular weight water-soluble chitosan (LMWSC) with high reactivity and strong positive charge can be applied as a delivery system having function to carry in the specific tissue the bioactive material like poor solubility drug, or therapeutic gene and developed as a therapeutic system having good therapeutic efficiency. The most important factor for therapy of various diseases is to reveal the antigen or receptor expressed in specific lesion tissue and the antibody and ligand which can bind with antigen is to introduce at the biomaterials for enhancement the therapeutic efficiency. The studies for cationic synthetic polymer as drug or gene delivery have been actively performed, but it has many problems such as toxicity in the body, therapeutic efficiency. From this point of view, this article demonstrated the introduction of functional groups to target the specific tissue and therapeutic strategy using the modification of LMWSC with free-amine group. The development of these delivery system will provide a positive vision for cancer therapy.

• Journal of the Korean GEO-environmental Society
• /
• v.17 no.10
• /
• pp.45-53
• /
• 2016

At present, coffee consumption amount is annually on the rise in Korea, which results in about 0.27 million tons of coffee waste annually. They are mostly classified as food waste and deserted with moisture contained, being a serious environmental issue. Existing slope greening techniques, which are vegetation based soil-media hydroseeding measures, have problems such as lack of coherence, dryness or lack of organic matters. Therefore in order to assess usability of Spent Coffee Ground (SCG), medium-to long-term growth test was conducted under the indoor and outdoor conditions. According to the result of growth test, when SCG was mixed with existing base materials, moisturizing power increased and organic matter content was reinforced, promoting germination and growth in a medium term. Among others, under the condition when supply of water was discontinued, withering rate was lower than existing base materials and diverse phenomena resulting from lack of nutrition decreased. Therefore, SCG as a waste organic matter with abundant nitrogen has the characteristic of inhibiting early growth but was found to have a quality favorable to long-term growth resulting from water containing ability and the supply of organic mater and is judged to be a material to replace or complement existing base materials.

• Analytical Science and Technology
• /
• v.26 no.1
• /
• pp.34-41
• /
• 2013

Split-flow thin cell (SPLITT) fractionation (SF) is a rapid separation technique capable of separating colloidal particles or macromolecules into two or more fractions. SF allows fractionations in a preparative scale as sample is fed continuously. Generally SF uses a thin ribbon-like channel equipped with two flow stream splitters at the inlet and outlet of the channel. Thus there exist two flow inlets and two flow outlets at the top and bottom of the inlet and outlet of the channel, respectively. There are two operating modes in SF, conventional mode and full-feed mode (FFD). Although the resolution in the FFD mode is lower than that in the conventional mode, FFD mode has some merits. The design of the channel and operation are simpler in the FFD mode, as it does not require the feeding of the solvent. Thus there is no flow stream splitter at the channel inlet, and only one pump is needed, unlike the conventional mode, where two pumps are required for the feedings of the sample and the solvent separately. Also the sample is not diluted in the FFD mode as there is no solvent feeding, which is important for fractionation samples with low colloidal concentrations such as environmental samples. For some of environmental samples, pre-concentration is often required. In this study, a new large-scale splitter-less FFD-SF channel was implemented, where there is no splitter at the outlet as well as at the inlet of the channel. It was possible to build the channel in a much larger dimension than conventional ones, allowing much higher sample throughput (TP). The new channel was tested and optimized with polyurethane (PU) latex beads, and then applied to large-scale separation of Polyacrylate (PA).

• Investigative Magnetic Resonance Imaging
• /
• v.12 no.2
• /
• pp.188-196
• /
• 2008

Purpose : To describe the clinical, MR imaging, and pathologic findings of pediatric meningiomas. Materials and Methods : The authors retrospectively reviewed the medical records and MR images of 16 pediatric patients with pathologically proven meningioma. Mean patient age at diagnosis was 14 years (range, 3-18). MR images were reviewed for details of lesion sizes, locations, signal intensity (SI), marginal characteristics, internal architectures, enhancements, and dural and parenchymal changes. The findings of other imaging modalities and of pathological examinations were also analyzed. Results : Mean tumor size was 5.24 cm (range, 1.3-18.1 cm) and locations were supratentorial in 12 and infratentorial in 4. SI of masses were variable, that is, high in 9, iso in 4, and low in 3 on T2 weighted images (T2WI), and low (n=11), iso (n=4), or high (n=1) on T1WI images. All lesions were visualized as well-demarcated enhancing masses. Five of the tumors were heterogeneous with cystic or necrotic components. Dural attachment was observed in 11 patients and adjacent brain edema in 10. Tumors exhibited hyperdense (n=6) or isodense (n=4) on non-enhanced CT scans, and 3 of the 7 angiograms demonstrated blood supply from the internal carotid artery. Pathologic examinations revealed the following subtypes; transitional cell (n=4), meningotheliomatous (n=4), chordoid (n=2), fibrous (n=2), clear cell (n=1), hyalinized (n=1), rhabdoid papillary (n=1), and atypical (n=1). Conclusion : Pediatric meningiomas occur usually in teenagers, have diverse pathological types, and may produce atypical imaging findings, such as, a heterogeneous internal content or findings suggestive of intraaxial tumors.

• Proceedings of the Korean Society of Soil and Groundwater Environment Conference
• /
• 2002.09a
• /
• pp.253-256
• /
• 2002

거제도는 남쪽에서 두 번째로 큰 섬으로써 총면적은 399.96$\textrm{km}^2$이며 총면적의 71.85%가 임야로 이루어져 있고 하천이 짧으며 유역면적이 좁은 관계로 지하수의 함양이 어려우며 해안으로 유출되는 지하수가 상당량이 될 것으로 사료되었다. 따라서 유출지하수의 특성을 연구하여 지하수의 유출가능성이 높은 지역을 찾을 수 있도록 여러 가지 분석을 통하여 알아보았다. 이를 위하여 기본적으로 기온, 강수량 등의 기상자료와 지하수온도, 지하수위등의 수문자료 및 해수표면온도 등의 해양관측자료를 이용하였으며, 해수와 지하수의 온도차가 많은 달의 Lanset 7 ETM+ 인공위성 영상자료와 NOAA 인공영상자료를 이용하여 온도자료를 비교하고, 각개 영사의 열분포도를 분석함으로써 유출지하수의 가능성이 높은 지역을 추출하였다. 추출한 지역에서 인구밀집지역, 공단지역, 기 공급지역을 제외하였으며, 수문지질학 적으로 유리한 지역을 선정하고, 평균해수분포차가 큰 지역을 추출함으로써 이후에 이루어질 현장조사시에 접근이 용이하도록 하였다. 연구결과 거제도 일대의 해안유출지하수 가능지점은 10개소 이상이며 자연적, 사회학석인 여건을 고려한다면 지하수개발가능 지역은 6개 정도로 예상된다. 또한 해수면의 온도와 지하수의 온도가 차이가 클 때는11~13$^{\circ}C$의 분포를 보이고 있어, 이후 이와 같은 연구에 충분히 활용할 수 있을 것이며, 해상도가 높은 자료와 연계하면 보다 정확한 자료의 추출이 가능해 앞으로의 국내에 활용되지 못한 수자원 개발에도 많은 도움이 될 것으로 판단된다.하게도 유기물과의 친화력이 높은 것으로 알려진 Cu 역시 F1과 F2에 대하여 높은 함량을 나타내어 오염원으로부터의 Cu의 확산을 지시하였다. 외국에 비하여, 그동안 국내에서는 사격장 주변의 자연환경변화에 관하여 연구된 결과가 거의 전무하였다. 본 연구 결과는, 이와 유사한 사격장 주변 환경에서의 중금속 분포와 거동 특성에 대하여 종합적인 모니터링(즉, 체계적인 환경지구화학적 조사ㆍ연구)이 시급함을 시사해 주고 있다.할 수 있었다.연구지역을 대상으로 추정한 함양율은 지하수이용에 따른 지하수위하강에 대한 보정을 할 필요가 있으며 지하수이용실태조사를 추가로 하여 그 이용량만큼을 지하수함양량에 더하여야 할것이다.의 특성 등을 고려하여 거기에 맞는 기술들을 복합적으로 또는 단독으로 사용하되 처리방법 채택 시 신중을 기할 것이 요망된다.정시에는 SeaWiFS 위성과 관련된 global algorithms 중에서 490nm와 555nm의 복합밴드를 포함하는 OC2 알고리즘(ocean color chlorophyll 2 algorithm)을 사용하는 것이 OC2 series 및 OC4 알고리즘보다 좋은 추정 값을 도출할 수 있을 것으로 기대된다.환경에서는 5일에서 7월에 주로 이 충체의 유충이 발육되고 전파되는 것으로 추측되었다.러 가지 방법들을 적극 적용하여 금후 검토해볼 필요가 있을 것이다.잡은 전혀 삭과가 형성되지 않았다. 이 결과는 종간 교잡종을 자방친으로 하고 그 자방친의 화분친을 사용할 때만 교잡이 이루어지고 있음을 나타내고 있다. 따라서 여교잡을 통한 종간잡종 품종육성 활용방안을 금후 적극 확대 검토해야 할 것이다하였다.함을 보

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.22 no.5
• /
• pp.485-500
• /
• 2020

Due to various advantages such as small facilities, ease of construction and so on, the grouting technology which is widely used in construction field has developed remarkably compared with the past. However, the efforts to improve the homogeneity of quality, long-term durability and environmental problems have been continued. In recent years, new grouting method has been developed in order to solve problems such as low strength, durability and leaching phenomenon of liquid glass (sodium silicate) grouting material in Korea. A newly developed method integrates the injection material with the ground by the self-healing material of crystallization growth type. For this reason, it is known that improvement of the durability and water quality of the ground, prevention of leaching, and environment friendliness can be expected. The present study applied a newly developed method to test sites and verified its effect such as injection range, improvement effect, waterproofing performance and so on. Standard penetration test, field permeability test, borehole shear test, pressuremeter test and pH test were conducted, and the results were compared between before and after developed method application. As results of tests, the field applicability and improvement effect of developed method were proved to be excellent.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.14
• /
• pp.97-109
• /
• 1973

1. The relatively lower prehardening temperature was more effective on increase of the hardiness of the intermediately hardy varieties than the higher one but either the extremely hardy or nonhardy varieties did not respond to the temperature as much as the intermediate types. 2. Five degree Centigrade was generally more favorable than $2^{\circ}C$ on hardening of the plants, especially when frozen at higher temperature for shorter duration. 3. It appears that photoperiod during prehardening and hardening did not play so important role as temperature on the hardiness. 4. The higher the soil moisture content, the higher the frost injury occurred. 5. Application of nitrogen increased markedly the hardiness and % DM of the plants. Percentage of dry matter of young seedlings might be used as an easy and rough criterion for evaluating hardiness since there was a highly significant regression of varietal frost injury on the %DM. 6. Four days appeared to be enough for hardening of plants although the plants increased gradually the hardiness as duration of hardening extended. Dehardening of the plants at relativity higher temperature took place rapidly within one to four days. 7. Under this controlled environment, freezing at about $-8^{\circ}C$ for 24 hours seemed the best for the purpose of evaluating the hardiness to low temperature. 8. It is believed that assessment of frost injury should be done at least one week after freezing. Some varieties showed strong ability to recover from the damage as recovery period was extended. 9. As a whole, Cd 80 and 83 were the most hardy and followed by Cappelle and Maris Otter. Four. winter oats varieties and Jufy I belonged to the intermediate type while the other three spring varieties were nonhardy at all. Peniarth was comparable with Maris Otter in hardiness. S 147 appeared the least hardy among the winter oats varieties. 10. It is evident that water-soluble carbohydrate content is associated with the hardiness to some extent but not primary factor involved in hardiness.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2002.11b
• /
• pp.1487-1490
• /
• 2002

최근 분산 컴퓨팅 환경은 급진적으로 광역화되고, 이질적이며, 연합형태의 광역 시스템 구조로 변화하고 있다. 이러한 환경은 네트워크상에 광범위한 서비스를 제공하는 통신 네트워크 기반에서 구현된 수많은 객체로 구성된다. 더욱, 지구상에 존재하는 모든 객체들은 이름이나 속성에 의해 중복된 특성을 갖는다. 이러한 같은 특성을 갖는 객체들은 중복 객체로 정의된다. 그러나 기존의 네이밍이나 트레이딩 메커니즘은 독립적인 위치 투명성이 결여로 중복된 객체들의 바인딩 서비스 지원이 불가능하다. 서로 다른 시스템 상에 존재하는 중복된 객체들이 동일한 서비스를 제공한다면, 각 시스템의 부하를 고려하여 클라이언트의 요청을 분산시킬 수 있다. 이러한 이유로 본 논문에서는 광역 컴퓨팅 환경에서 중복된 객체들의 위치 관리뿐만 아니라 시스템들간의 부하 균형화를 유지하기 위해서 최소부하를 갖는 시스템에 위치한 객체의 선정하여 동적 바인딩 서비스를 제공할 수 있는 새로운 모델을 설계하고 구현하였다. 이 모델은 네이밍 및 트래이딩 기능을 통합한 서비스에 의해 중복된 객체들에 대한 단일 객체 핸들을 얻는 부분과, 얻어진 객체핸들을 사용하여 위치 서비스에 의해 하나 이상의 컨택 주소를 얻는 부분으로 구성하였다. 주어진 모델로부터, 우리는 Naming/Trading 서비스와 위치 서비스에 의한 전체 바인딩 메커니즘의 처리과정을 나타내고, 통합 바인딩 서비스의 구성요소들에 대만 구조를 상세하게 기술하였다. 끝으로 우리의 모델을 구현하기 위해, 윈도우 운영체제와 Solaris 2.5/2.7에서 사용되는 CORBA 사양을 따르는 VisBroker 4.1과 자바 언어, SQL Server 2000 그리고 LSF를 이용하였다. 그리고 구현 환경과 구성요소에 대한 수행 화면을 보였다.ool)을 사용하더라도 단순 다중 쓰레드 모델보다 더 많은 수의 클라이언트를 수용할 수 있는 장점이 있다. 이러한 결과를 바탕으로 본 연구팀에서 수행중인 MoIM-Messge서버의 네트워크 모듈로 다중 쓰레드 소켓폴링 모델을 적용하였다.n rate compared with conventional face recognition algorithms. 아니라 실내에서도 발생하고 있었다. 정량한 8개 화합물 각각과 총 휘발성 유기화합물의 스피어만 상관계수는 벤젠을 제외하고는 모두 유의하였다. 이중 톨루엔과 크실렌은 총 휘발성 유기화합물과 좋은 상관성 (톨루엔 0.76, 크실렌, 0.87)을 나타내었다. 이 연구는 톨루엔과 크실렌이 총 휘발성 유기화합물의 좋은 지표를 사용될 있고, 톨루엔, 에틸벤젠, 크실렌 등 많은 휘발성 유기화합물의 발생원은 실외뿐 아니라 실내에도 있음을 나타내고 있다.>10)의 $[^{18}F]F_2$를 얻었다. 결론: $^{18}O(p,n)^{18}F$ 핵반응을 이용하여 친전자성 방사성동위원소 $[^{18}F]F_2$를 생산하였다. 표적 챔버는 알루미늄으로 제작하였으며 본 연구에서 연구된 $[^{18}F]F_2$가스는 친핵성 치환반응으로 방사성동위원소를 도입하기 어려운 다양한 방사성의 약품개발에 유용하게 이용될 수 있을 것이다.었으나 움직임 보정 후 영상을 이용하여 비교한 경우, 결합능 변화가 선조체 영역에서 국한되어 나타나며 그 유의성이 움직임 보정 전에 비하여 낮음을 알 수 있었다. 결론: 뇌활성화 과제 수행시에 동반되는 피험자의 머리 움직임에 의하여 도파민 유리가 과대평가되었으며 이는 이 연구에서 제안한 영상정합을 이용한 움직임 보정기법에 의해서 개선되

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.38 no.6
• /
• pp.1021-1028
• /
• 2018

As entering the international construction market became more difficult than the past, ODA projects can be a breakthrough for domestic engineering companies to enter the international market. However, since many companies compete for limited projects, it is necessary to reinforce the competitiveness of bidding success. The competitiveness is the result of accumulating experience, reputation, and networking through partnering. Therefore, depending on which partnering strategy has been taken over a long period, the bidding success is decided. The objective of this study is to identify the effective partnering strategy for bidding success. For this, the World Bank bid results, focusing on consulting projects in Vietnam, are collected. Using the bid results, inter-firm network representing the partnering relationship is constructed and the Social Network Analysis is conducted. After then, by conducting the Logistic Regression Analysis, effective partnering strategies are suggested. The result shows that the diversification strategy is advantageous for transportation and city development projects and the concentration strategy is advantageous for water projects. The partnering strategy for the consulting project proposed in this study will be used as a reference for the domestic engineering companies to enter the Vietnam construction market in the future.

• Journal of the Korean Electrochemical Society
• /
• v.22 no.3
• /
• pp.87-103
• /
• 2019

Nonaqueous organic electrolyte solution in commercially available lithium-ion batteries, due to its flammability, corrosiveness, high volatility, and thermal instability, is demanding to be substituted by safer solid electrolyte with higher cycle stability, which will be utilized effectively in large-scale power sources such as electric vehicles and energy storage system. Of various types of solid electrolytes, composite solid electrolytes with polymer matrix and active inorganic fillers are now most promising in achieving higher ionic conductivity and excellent interface contact. In this review, some kinds and brief history of solid electrolyte are at first introduced and consequent explanations of polymer solid electrolytes and inorganic solid electrolytes (including active and inactive fillers) are comprehensively carried out. Composite solid electrolytes including these polymer and inorganic materials are also described with their electrochemical properties in terms of filler shapes, such as particle (0D), fiber (1D), plane (2D), and solid body (3D). In particular, in all-solid-state lithium batteries using lithium metal anode, the interface characteristics are discussed in terms of cathode-electrolyte interface, anode-electrolyte interface, and interparticle interface. Finally, current requisites and future perspectives for the composite solid electrolytes are suggested by help of some decent reviews recently reported.