• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.5 no.1
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• pp.83-92
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• 1994

Paroxetine is a potent and selective serotoin re-uptake inhibitor. It is well known as an effective and safe antidepressant and increasingly used for neurotic or non-psychotic depression with anxiety symptoms. The present study assessed antidepressant and antianxiety efficacy and tolerability of paroxetine against placebo in child-adolescent and adult depressive neurosis patients. 232 subjects aged 8-55 years and meeting DSM-III-R criteria for depressive neurosis or dysthymia were divided into 8 subgroups according to their sex and age(8-11 yeard old, 12-17 years old, 18-35 years old and 36-55 years old subgroup in each male and female group). In each subgroup, the randomly assigned half of the patients were treated with paroxetine(10-30mg/day) and the others with placebo for the first 2 weeks in double blind fashion. After 1 week of drug-washout period, paroxetine and placebo groups were crossed over. The depression and anxiety symptoms were assessed with Hamilton Depression Scale(HDS) and Hamilton Anxiety Scale(HAS) at baseline and every 1 week during the trial periods. The levels of reduction in HDS and HAS scores from baseline after 2-week trial were compared between paroxetine- and placebo- treated periods by paired t-test. In all the 8 subgroups, statistically significant differences between paroxetine and placebo were found on the antidepressant efficacy after 2-week treatment. The antidepressant efficacy of paroxetine compared to placebo was most prominent in child and adolescent female groups. On anxiety symptoms, paroxetine was also significantly more effective than placebo. The antianxiety efficacy of paroxetine compared to placebo was most prominent in male and female child groups and young adult female group aged 18-35 years. As for the adverse effects of paroxetine, 3 out of 232 subjects reported mild indigestion and abdominal pain. however, in all the 3 cases, the symptoms improved without reduction of dosage or discontinuation of the drug. In conclusion, paroxetine showed significantly higher antidepressant and antianxiety efficacy compared to placebo in child-adolescent and adult depressive neurosis patients after 2-week treatment. Further trials of paroxetine in depressive neurosis are warranted to elucidate the long-term antidepressant and antianxiety efficacy of paroxetine.

• Sleep Medicine and Psychophysiology
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• v.14 no.1
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• pp.26-32
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• 2007

Objectives: Angiotensin-converting enzyme (ACE) gene polymorphism has been reported to be associated with depression and therapeutic outcome in depression. The purpose of this study was to determine whether ACE gene polymorphism is associated with seasonal variation in mood and behavior in a young Korean college student sample. Methods: 297 young Korean medical students were recruited in this study. All subjects were free of major medical and psychiatric problems. They were genotyped for the ACE gene polymorphism and evaluated the seasonal variation in mood and behavior by the Seasonality Pattern Assessment Questionnaire (SPAQ). Results: Global Seasonality Score (GSS) of SPAQ between three genotypes were not different. However, comparison of the group that showed seasonality of mood and behavior during winter with the group that did not showed seasonality indicated significant difference in genotype distribution ($x^2=6.79$, p=0.034). The D allele non-carrier (ll genotype) frequency was significantly higher in winter seasonality group than non-seasonality group ($x^2=6.59$, p=0.010；odds ratio [OR]=2.27, 95% confidence interval [CI] 1.20-4.28). Conclusion: These results suggest that the ACE gene polymorphism is related to winter-type seasonality in a Korean population.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.9 no.2
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• pp.237-246
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• 1998

Objectives and Methods：This study investigated clinical characteristics, treatment modality, outcome of 57 children and adolescent inpatients(male 53, female 4) who were diagnosed as pervasive developmental disorder(PDD) by DSM-Ⅳ criteria recent five years. Results：1) The mean age at admission was $96{\pm}28.2$ months, and the mean age at which they first visited treatment facility was $52{\pm}26.6$ months. The mean hospitalization period was $43.7{\pm}31.3$ days. 2) Diagnosis：Twenty-seven(47.4%) of subjects met DSM-Ⅳ criteria for PDD NOS. Fifteen (26.3%) met for autistic disorder, nine(15.8%) met for Asperger's syndrome, and two(3.5%) met for childhood disintegrative disorder. 3) Comorbid diagnosis：The most common comorbid dignosis was attention deficit hyperactivity disorder(23.8%). 4) IQ test：IQ test for twenty-eight subjects was possible. The Average of the subjects was $70{\pm}27.5$. Fifteen(53.6%) of the subjects were approximate or under 70. 5) Neurology Abnormality：EEG findings of eleven(21.2%) subjects were abnormal, brain CT or MRI findings of eight subjects(21.6%) were abnormal. 6) Family Hx：Depressive disorder were found in Eight mothers(14%). Familial loading was found in twenty families(35.1%), and familial loading of PDD was found in three(5.3%). Conclusion：The most important thing for the management of PDD is early detection and early treatment. To do so, multidisciplinary team approach should be emphasized.

• Korean Journal of Social Welfare
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• v.65 no.2
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• pp.313-334
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• 2013

A study aims to assess Korean mental health literacy and analyze the characteristics of vulnerable population. This study presented typical vignettes of schizophrenia, depression and alcoholism to 1,197 adults randomly. All respondents were asked for recognition of mental illness, beliefs about causes, professional help and self-help, stigma for receiving psychiatric treatment for the person described. The results showed that the recognition of mental health problem in a vignette was very poor and that personal causes were seen by public as more important than environmental and bio-genetic causes. When the public were asked about various professional therapies and self-help activities, psychotherapy was favored while other professional help were considered to be less helpful than self-help activities. Among professionals, psychiatrist were viewed as most helpful. We used cluster analysis to compare high mental health literacy group with low mental health literacy group(vulnerable population). Vulnerable population were found to be more aged and to live in county area. We proposed government initiated program for enhancing public mental health literacy.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.05a
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• pp.652-654
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• 2018

Recently there are many people who suffer from a mental problem like depression or anxiety caused by the stress of employment or school works. Some mental care agencies serve a campaign for them, but it's less accessible due to the geographic distance. And before taking the service, people should find out what is a better psychological test for them to diagnose the problem. Furthermore, it is inconvenient that keeping the diagnosis which is written in some papers. In his paper, in order to solve these problems, suggests the novel platform that serves psychological tests to users and stores results into database so that involved agencies could contact quickly. The psychological tests BAI, BDI, PHQ-15, and Q-15 were used to verify the reliability and effectiveness of the platform.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.31 no.1 s.49
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• pp.127-134
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• 2005

This study is to identify the psychological effect of make-up, to examine women's tendency toward make-up and to figure out relationships between their psychological properties and its functions. This study has verified that makeup has a positive effect on their interpersonal relationships, psychological reaction and self- confidence as well as it meets their fundamental aesthetic needs. And further studies about psychological reason why they wear makeup need to be made. Makeup has an effect on their looks and it has a psychological effect of being able to decorate and move their mind. finally, it is anticipated that the study for psychological approach to makeup could contribute on the study for positive makeup treatment.

• Journal of the Health Care and Life Science
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• v.9 no.2
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• pp.373-381
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• 2021

The purpose of this study was to examine the correlation between the effectiveness of SUKI alternative therapy and scalp massage, and to contribute to the application and activation of hair SUKI alternative therapy. The research method was first to examine the understanding of SUKI alternative therapy through the concept of SUKI alternative therapy, the characteristics of SUKI alternative therapy, and points to be aware of during SUKI alternative therapy. The correlation between SUKI alternative therapy and scalp massage was investigated by reviewing research and others. As a result, SUKI replacement therapy had significant effects such as stress, depression, high blood pressure, muscle pain, skin wrinkles and elasticity. has been shown to affect treatment. Therefore, it is expected that SUKI replacement therapy can be applied to hair SUKI replacement therapy to improve the health and quality of life of modern people.

• 한국노년학
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• v.37 no.1
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• pp.1-14
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• 2017

The purpose of this study was to examine the effect of vision and hearing limitation on the onset of disability among Korean elderly with the consideration of social participation and depression. Study population consisted of 2,670 people aged 65 and above who participated in both the 1st(2006) and 2nd(2008) wave of the Korean Longitudinal Study of Aging(KLoSA), and also reported no ADL or IADL disability in 2006. As the results, first, it found that vision and hearing limitation, social participation, and depression were significant risk factors for the onset of IADL disability in unadjusted analysis. After multivariable adjustment, however, only vision limitation showed significant association with the onset of IADL disability. Second, in the logistic analysis with four categorized variables(vision/hearing limitation + social participation, vision/hearing limitation + depression), the elderly who had vision or hearing limitation had a significantly 1.7 times higher odds ratio for disability onset if they also had low social participation compared with those who had no vision or hearing limitation, and high social participation. Whereas, depression was not significantly associated with the relationship between vision or hearing limitation, and disability onset. The study suggests that the intervention program developed to prevent social isolation of older people with vision or hearing limitation, may be helpful to reduce and postpone the risk of disability onset as well as early detection and treatment of vision or hearing problems.

• Herbal Formula Science
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• v.13 no.1
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• pp.223-233
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• 2005

As woman receive many stress during pregnancy and delivery, they happen to contract to psychopathy like a postpartum depression. Postpartum depression is a serious problem if they are not treated early enough the unhappy seriousness can be resulted. A 32-yeared-old female patient with postpartum depression was taken to Dongshin University oriental medical hospital on April, 28, 2003. We diagnosed this patient as postpartum depression, which originated from and efficiency of vital energy and blood. We treated this postpartum depression patient with herb medicine(Cami-Boheo-tang),acupuncture, moxibustion, and psychical therapy. After the oriental medical treatments, the patient was improved in all complains of the postpartum disease. After this, further study and approach will be needed about the disease of the postpartum depression.

• Archives of Obesity and Metabolism
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• v.1 no.1
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• pp.39-42
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• 2022

Obesity is a chronic disease associated with severe complications. A major complication of obesity is depression, which can worsen obesity and vice versa. In addition, most antidepressants or antipsychotics cause weight gain, and the relationship between obesity and depression is clinically critical. However, treatment of obese patients with major depressive disorder is complicated. Bariatric physicians should provide appropriate behavioral interventions alongside pharmacological treatment, considering psychiatric symptoms, drug side effects, and drug interactions. Two successful cases of moderate-to-severe obese patients with major depressive disorder who had been treated for obesity using behavioral intervention therapy along with liraglutide will be discussed. This report highlights the safety and efficacy of liraglutide treatment of obesity in patients with depression who take antidepressants and antipsychotics.