• Journal of radiological science and technology
• /
• v.35 no.3
• /
• pp.237-248
• /
• 2012

Postpartum depression(PPD) of women with depression increased frequency of thyroid disease, and so the correlations for depression and thyroid disease has been the subject of discussed whether. The purpose of this study was to predict the prevalence of PPD and the correlation between PPD and thyroid disease through ultrasonography. January 2010 to November 2011, Obstetrics & Gynecology in M-clinical center admitted 230 patients within 1 year postpartum were enrolled. EPDS by PPD scale depression screening and general characteristics of subjects were investigated and thyroid was examined that ultrasonography and thyroid blood tests. A total of 230 patients non PPD group were 53.0% and PPD group were 47.0%. In ultrasonography, among 27 patients who changed in size of thyroid, non PPD group were 14.8% and PPD group were 85.2%. Among 124 patients who thyroid nodules were presence, non PPD were 35.8% and PPD group were 64.2%. In ultrasonography, PPD group were higher incidence than non PPD group were changes in size of thyroid and the presence of nodules. There was significant difference between the changed in size of thyroid and thyroid nodules were presence the two group. Definitive histopathological diagnosis was benign in 33 patients (non PPD group were 45.5%, PPD group were 54.5%), malignancy in 5 patients (only PPD group were 100%), thyroiditis in 3 patients (non PPD group were 33.3%, PPD group were 66.7%). The results of thyroid blood tests, abnormal TSH level were 7 patients (non PPD group were 28.6%, PPD group were 71.4%) and abnormal Free T4 level were 9 patients (non PPD group were 44.4%, PPD group were 55.6%). There was no significant difference between the abnormal TSH level and Free T4 level of the two group. 5 patients were diagnosed as thyroid dysfunction. Of these, 2 patients were subclinical hyperthyroidism in non PPD group, 2 patients were subclinical hyperthyroidism and 1 patient was subclinical hyperthyroidism in PPD group. This study was significant the correlation between PPD and thyroid gland disease through ultrasonography. And the objective results of this study might be able to provide guideline that understanding, prevention and treatment for PPD and thyroid disease.

• The Korean Journal of Health Service Management
• /
• v.5 no.4
• /
• pp.137-147
• /
• 2011

본 연구는 일부지역 장애아동 양육자의 정신과적 문제를 알아보기 위해 우울증 지수를 검사하고 분석함으로서 그 심각성을 확인하고 장애아동 양육자의 정신보건의 필요성을 알리기 위한 기초자료를 제공하는 데 목적이 있다. 본 연구는 2011년 8월부터 9월까지 경주 및 인근지역에서 지적장애아동과 지체장애아동을 둔 전업주부의 정신과적 문제를 알아보기 위해 양육 스트레스로 인한 우울증 정도를 알아보았다. 연구대상자는 3개의 치료기관 및 치료 관련기관에서 지적장애 또는 지체장애 아동을 양육하고 있는 부모 각 20명씩을 대상으로 하였다. 우울증 평가도구는 한국형 우울증 검사(Korean Depression Scale; KDS)를 이용하였다. 결과는 첫째, 지적장애아동과 지체장애아동 양육자 모두 우울증이 있는 것으로 나타났고 각각의 차이 비교에는 유의성이 없었다. 둘째, 지적장애아동과 지체장애아동 양육자의 우울증 세부항목에서는 의욕상실 부분에서만 유의성이 있었다. 셋째, 지적장애아동 양육자의 우울증 세부항목간의 비교에서는 유의성이 있었다. 넷째, 지체장애아동 양육자의 우울증 세부항목간의 비교에서는 유의성이 있었다. 다섯째, 지적장애아동 양육자의 우울증과 세부항목의 상관관계에서는 의욕상실에서 유의한 상관성이 있었다. 여섯째, 지체장애아동 양육자의 우울증과 세부항목의 상관관계에서는 의욕상실에서 유의한 상관성이 있었다. 본 연구에서는 두 장애아동의 양육자간 차이는 없었으며 우울증은 장애유형에 상관없이 모두 나타났다. 그리고 세부항목과 우울증의 상관성에서는 의욕상실에서 유의한 상관성을 보였다. 이것은 장애아동의 양육에서 치료의 지연으로 인한 의욕상실에서 우울증이 많이 유발됨을 알 수 있다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.5 no.1
• /
• pp.12-27
• /
• 1994

Until recently there were arguments on the existence and the definition of childhood depression. In DSM-III(1980) childhood depression was accepted as the formal psychiatric disorder in childhood. As the diagnostic criteria for childhood depression is less clearly defined than those for other psychiatric disorders as well as prominent age-related variations in depression symptomatology, informations from various sources are very important in accurate diagnosis of childhood depression. Present study reviewed various assessment methods such as self-report questionnaires, interviews, behavior rating scales, structured tests and projective techniques with discussion on the merits and limitations of each method. Also several issues on the reliability and the validity of assessment techniques for childhood depression were discussed.

• Korean Journal of Biological Psychiatry
• /
• v.8 no.1
• /
• pp.20-36
• /
• 2001

The debate about whether depressive disorders should be divided into categories or arrayed along a continuum has gone for decade, without resolution. In our review, there is more evidence consistent with the spectrum concept than there is with the idea that depressive disorders constitute discrete clusters marked by relatively discontinuous boundaries. First, "depression spectrum", "is there a common genetic factors in bipolar and unipolar affective disorder", "threshold model of depression" and "bipolar spectrum disorder" are reviewed. And, a new subtype of depression is so called SeCA depression that is a stressor-precipitated, cortisol-induced, serotonin-related, anxiety/aggression-driven depression. SeCA depression is discussed. But, there is with the idea that depressive disorders constitute discrete subtypes marked by relatively discontinuous boundaries. This subtypes of depressive disorder were reviewed from a variety of theoretical frames of reference. The following issues are discussed ; Dexamethasone suppression test(DST), TRH stimulation test, MHPG, Temperament Character Inventory(TCI), and heart rate variability(HRV).

• Sleep Medicine and Psychophysiology
• /
• v.14 no.2
• /
• pp.92-98
• /
• 2007

Objectives: Obstructive sleep apnea syndrome (OSAS) is the most common form of sleep-disordered breathing and often presents with comorbid depressive symptoms. In this study, we evaluated the relationship between depressive symptoms and sleep parameters as measured by nocturnal polysomnography (NPSG) and simultaneous wrist actigraphy. Methods: Two hundred sixty-four subjects with clinically suspected cases of OSAS underwent one-night polysomnography, while simultaneously wearing a wrist actigraphy device. They also completed two questionnaires；the Epworth Sleepiness Scale-Korean version (ESS-K) and the Beck Depression Inventory (BDI). Of the cases studied, 105 subjects were proven by NSPG to have OSAS without other sleep disorders. NPSG and wrist actigraphy data from the subjects were analyzed. Pearson correlation and paired t-test were used in order to evaluate the relationship between depressive symptoms and sleep-parameters. Results: Mean age of the subjects was $46.1{\pm}13.1$ years. Means of the ESS-K score and BDI scores were $10.9{\pm}4.7$ and $12.8{\pm}8.1$, respectively. NPSG sleep parameters significantly differed from those of wrist actigraphy. There was no correlation found between subjects' respiratory disturbance index (RDI) and BDI scores. When directly comparing sleep parameters between subjects who were more depressed versus subjects who were less depressed, both total sleep time and sleep efficiency were decreased in the more depressed. A correlation between RDI and ESS-K scores was also found in the more depressed group. Conclusions: Although our findings suggest that there is no relationship between RDI and depressive symptoms, there are other significant differences in the sleep parameters between subjects who are more depressed versus those without depression. We recommend that patients with depression should also be evaluated for clinical symptoms of OSAS.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.9 no.2
• /
• pp.190-197
• /
• 1998

Objectives：This study was conducted to investigate the diagnostic utility of the Rorschach schizophrenia/depression/coping deficite index in child-adolescent parent groups(schizophrenia, depression,depressive conduct disorder). Methods：Three child-adolescent parent groups(schizophrenia(18), depression(20), depressive conduct disorder(19)) were individyally assessed using the Rorschach test and schizophrenia/depression/coping deficite index scores were analyzed. Results：The results showed significant difference among three groups on only SCZI and significantly higher SCZI score of schizophrenia group than other two groups. When the critical value of SCZI was 4, diagnostic hit rate was 96.5%, and when the critical value of DEPI was 3, diagnostic hit rate was 57.9%, and when the critical value of CDI was 4, diagnostic hit rate was 66.6%.

• Sleep Medicine and Psychophysiology
• /
• v.21 no.1
• /
• pp.5-13
• /
• 2014

Objectives: Depression, sleep complaints and cognitive impairments are commonly observed in the elderly. Elderly subjects with depressive symptoms have been found to show both poor cognitive performances and sleep disturbances. However, the relationship between sleep complaints and cognitive dysfunction in elderly depression is not clear. The aim of this study is to identify the association between sleep disturbances and cognitive decline in late-life depression. Methods: A total of 282 elderly people who underwent nocturnal polysomnography in a sleep laboratory were enrolled in the study. The Korean version of the Neuropsychological Assessment Battery developed by the Consortium to Establish a Registry for Alzheimer's Disease (CERAD-K) was applied to evaluate cognitive function. Depressive symptoms were assessed with the geriatric depression scale (GDS) and subjective sleep quality was measured using the Pittsburg sleep quality index (PSQI). Results: The control group ($GDS{\leq}9$) when compared with mild ($10{\leq}GDS{\leq}16$) and severe ($17{\leq}GDS$) depression groups, had significantly different scores in the Trail making test part B (TMT-B), Benton visual retention test part A (BVRT-A), and Stroop color and word test (SCWT)(all tests p<0.05). The PSQI score, REM sleep duration, apnea-hypopnea index and oxygen desaturation index were significantly different across the three groups (all indices, p<0.05). A stepwise multiple regression model showed that educational level, age and GDS score were predictive for both TMT-B time (adjusted $R^2$=35.6%, p<0.001) and BVRT-A score (adjusted $R^2$=28.3%, p<0.001). SCWT score was predicted by educational level, age, apnea-hypopnea index (AHI) and GDS score (adjusted $R^2$=20.6%, p<0.001). Poor sleep quality and sleep structure alterations observed in depression did not have any significant effects on cognitive deterioration. Conclusion: Older adults with depressive symptoms showed mild sleep alterations and poor cognitive performances. However, we found no association between sleep disturbances (except sleep apnea) and cognitive difficulties in elderly subjects with depressive symptoms. It is possible that the impact of sleep disruptions on cognitive abilities was hindered by the confounding effect of age, education and depressive symptoms.

• Korean Journal of Psychosomatic Medicine
• /
• v.29 no.1
• /
• pp.42-48
• /
• 2021

Objectives : Based on the fact that cognitive functions decline known as comorbid symptoms of depression can precede depression, this study seeks to observe the effects of depressive symptoms and anxiety symptoms on cognitive function in healthy subjects. Methods : To recruit 50 general populations to evaluate cognitive and clinical symptoms and to find out the effects of clinical symptoms on cognitive functions, Pearson correlation and multivariate regression were conducted. Correlation analysis of subdomain cognitive function was conducted for reliability analysis. Results : Trail making test-B that evaluates the execution function correlates with depressive symptoms (r=0.300, p=0.03) and age (r=0.323, p=0.02). Depressive symptoms (β=0.304, p=0.03) and age (β=0.335, p=0.01) were significantly related to Trail making test -B (Adjusted R²=0.148). Subjective cognitive tests correlates with anxiety symptoms (r=0.434, p=0.002). In the correlation between cognitive functional items, Subjective cognitive tests was found to be correlated with other test except Spotter. Conclusions : In this study, depressive symptoms contribute independently to executive functions in addition to demographic characteristics such as age and duration of education. Given that cognitive decline is a common long-term clinical outcome in depression, we expect active early intervention and evaluation of cognitive function to be helpful.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.11 no.2
• /
• pp.209-220
• /
• 2000

The purpose of this study is to find out the characteristics of depressive episode about major depression and bipolar disorder in child and adolescent. The subjects of this study were 34 major depression patients and 17 bipolar disorder patients hospitalized at child and adolescent psychiatry in OO university children's hospital from 1st March 1993 to 31st October 1999. The method of this study is to review socio-demographic characteristics, diagnostic classification, chief problems and symptoms at admission, frequency of symptoms, maternal pregnancy problem history, childhood developmental history, coexisting psychiatric disorders, family psychopathology and family history and therapeutic response through their chart. 1) The ratio of male was higher than that of female in major depressive disorder while they are similar in manic episode, bipolar disorder. 2) Average onset age of bipolar disorder was 14 years 1 month and it was 12 years 8 months in the case of major depression As a result, average onset age of major depression is lower than that of bipolar disorder. 3) The patients complained of vegetative symptoms than somatic symptoms in both bipolar disorder and depressive disorder. Also, the cases of major depression developed more suicide idea symptom while the case of bipolar disorder developed more aggressive symptoms. In the respect of psychotic symptoms, delusion was more frequently shown in major depression, but halucination was more often shown in bipolar disorder. 4) Anxiety disorder coexisted most frequently in two groups. And there coexisted symptoms such as somartoform disorder, mental retardation and personality disorder in both cases. 5) The influence of family loading was remarkable in both cases. Above all, the development of major depression had to do with child abuse history and inappropriate care of family. It is apparent that there are distinctive differences between major depression and bipolar disorder in child and adolescent through the study, just as in adult cases. Therefore the differences of clinical characteristics between two disorders is founded in coexisting disorders and clinical symptoms including onset age, somatic symptoms and vegetative symptoms.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.16 no.2
• /
• pp.211-218
• /
• 2005

Objectives : The purpose of the study was to evaluate the related factors of depression in mothers bringing their offspring for evaluation or treatment of problematic behaviors. Methods : Fifty mothers were recruited through their offspring's evaluation or treatment for offspring's problematic behaviors. Psychological tests battery including Korean Wechsler Adult Intelligence Scale and the Korean Educational Development Institute-Wechsler Intelligence Scale for Children was administered to all mothers and their offspring. Mothers completed Korean version of Child Behavior Checklist (K-CBCL), and teachers completed Teacher's Report Form (TRF). On the basis of the maternal depression, the mothers were divided into two groups. Results : 1) Among the fifty mothers, $42\%$ of the mothers had depressive disorder, $16\%$ had anxiety disorder, and $42\%$ had no psychiatric disorder. 2) Depressed mothers rated significantly higher in aggressive behaviors, externalizing problems of K-CBCL in their children. 3) Children of depressed mothers had lower score in picture arrangement and coding subtests of KEDI-WISC than those of no psychiatric disorder mothers. 4) After controlling for the total problematic behavior scores of TRF, mother's depression is positively correlated with aggressive behaviors, externalizing problems, total problematic behaviors of K-CBCL, and negatively correlated with coding of KEDI-WISC. Conclusion : Children's aggressive behavior, externalizing behavior, total problematic behaviors and low coding score may be associated with mother's depression.