• Journal of Internet Computing and Services
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• v.7 no.4
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• pp.33-43
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• 2006

This paper proposes a method to extract coronary arteries effectively in the angiography, In general. DSA(Digital Subtraction Angiography) is a well-established technique for the visualization of coronary arteries, DSA involves the subtraction of a mask image, an image of a heart before the injection of contrast medium, from a live image, However, this technique is sensitive to the movement of background and can cause wrong detection due to the variance of background intensity between two images. Therefore, this paper solves the structural problem resulted from background movement by selecting an image which has the least difference of movement through the similarity analysis of background texture, and it extracts only the blood vessels effectively through local intensity correction of the selected images, Experimental results show that the proposed method has the lower false-detection rate and higher accuracy rate than existing methods.

• Journal of KIISE:Software and Applications
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• v.27 no.8
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• pp.804-814
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• 2000

In this paper, we propose an effective method to detect the regions of interests in the Videostrobokymography System. Videostrobokymography system is a medical image processing system for extracting automatically the diagnosis parameters from the irregular vibratory movements of the vocal fold. We detect the regions of interests through three steps. In the first step, we remove the noise in the input image and we find the minimum energy value in each frame. In the second step, we computed the edge by everage value for the one line. In the third step, the regions of interests can be extracted by using the Merge Algorithm which uses the variance of luminance as the feature points. We experimented this method for the vocal fold images of nineteen patients. In consequence, the regions of interests are detected in most vocal fold images. The method proposed in this study is efficient enough to extract the region of interests in the vocal fold images with the frame rate of 40 frames/second and the resolution of 200${\times}$280 pixels.

• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.9
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• pp.1351-1357
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• 2016

Green tea (Camellia sinensis) seed extract (GTSE) was prepared under various pretreatment conditions and used to investigate its extraction yield and anti-yeast activity. Anti-yeast activity of GTSE from seeds with or without the coats was the same, whereas the extraction yield was slightly higher in extract from seeds without the coat. Anti-yeast activity of GTSE from seeds with different water contents or particle sizes was the same, whereas the extraction yield was highest in extract from seeds with 7.3% moisture or a smaller particle size. Anti-yeast activity of defatted green tea seed extract (DGTSE) was the same as that of GTSE. Extraction yield was higher in DGTSE from defatted seeds by the oil press machine compared to hexane extraction. Defatted green tea seed (DGTS), a by-product from the oil extraction process, is a good natural source of anti-yeast preservative. The extraction yield and anti-yeast activity of DGTSE were investigated using various extraction solvents, temperatures, and times. The results show that water was an economic extraction solvent, and anti-yeast activity of DGTSE was unstable at $90^{\circ}C$. These results suggest that water, extraction temperature of $50^{\circ}C$, and extraction time of 4 h were the most efficient for extraction of anti-yeast compounds from DGTS.

• The Korean Journal of Pesticide Science
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• v.14 no.4
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• pp.339-346
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• 2010

The acute toxicity test of high bio-active plant essential oils was conducted with Lavender, Lemon eucalyptus and Cassia oils selected to develop environment-friendly insecticides. The results of acute oral toxicity using rats showed that $LD_{50}$ of over 2,000 mg/kg bw for Lavender, Lemon eucalyptus and Cassia oils. The calculated acute dermal $LD_{50}$ value of all testing materials was over 4,000 mg/kg bw. The Skin irritation test indicated that Lavender and Lemon eucalyptus oil have no irritation while Cassia oil has a moderate irritation. For the Eye Irritation test, the result showed no irritation for Lavender and Lemon Eucalyptus oil and irritation for Cassia oils. However, the irritation was not showed for Eye Irritationwashing test of Cassia oil. Consequently, the Lavender and Lemon eucalyptus oils were showed to be low in toxicity whereas Cassia oil indicated to cause a moderate irritation on the skin and eyes.

• Proceedings of the KSRS Conference
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• 2000.04a
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• pp.149-154
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• 2000

분류기법을 통해 얻어진 원격탐사 자료는 사용되기 이전에 그 정확성에 관한 신뢰도 검증을 해야 한다. 분류 정확도를 평가하기 위해서는 오분류행렬(confusion matrix)을 사용하여 정확도 평가를 하게 되는데, 이때 오분류행렬을 구성하기 위해서는 기준자료(reference data)에 대한 표본추출이 이루어져야 한다. 기준자료의 표본을 추출하는 기법간의 비교 및 표본 크기를 줄이고자 하는 연구는 많이 이루어져 왔으난, 추출된 표본들간의 거리를 줄임으로써 정확도 평가 비용을 감소시키고자 하는 연구는 미미한 실정이다. 따라서, 본 연구에서는 프랙탈 분석을 통하여 기준자료의 표본을 추출하였으며, 이를 바탕으로 기존의 표본추출 기법과 정확도 차이 및 비용효과 측면을 비교 분석하였다. 연구 결과, 프랙탈 분석을 통하여 표본을 추출하는 기법은 그 정확도 추정에 있어 기존적 표본 추출 기법과 큰 차이가 보이지 않았으며, 추출된 화소들이 가까운 거리에 군집해 있어 비용효과측면에서 보다 유리함을 확인하였다.

• Radiation Oncology Journal
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• v.25 no.3
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• pp.185-191
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• 2007

Purpose: This study was performed to investigate the effects of immune cell activation and the antitumor effect for the combination of treatment with X-irradiation and E/eutherococcus senticosus Maxim Root (ESMR) on mouse tumor cells. Materials and Methods: ESMR (250g) was extracted with 80% methanol, concentrated under decompression and lyophilized. To determine whether ESMR is able to activate the immune cells or not, the proliferation of splenocytes in vitro and the number of B cells and T cells in splenic lymphocytes in ESMR-pretreated mice were evaluated. X-irradiation was given to the mouse fibrosarcoma tumor cells (FSa II) by 250 kv X-irradiation machine. The cytotoxicity of ESMR was evaluated from its ability to reduce the clonogenecity of FSa II cells. In X-irradiation alone group, each 2, 4, 6 and 8 Gy was given to FSa II cells. In X-irradiation with ESMR group, 0.2 mg/ml of ESMR was exposed to FSa II cells for 1 hour before X-irradiation. Results: The proliferation of cultured mouse splenocytes and thymocytes were enhanced by the addition of ESMR in vitro. The number of B cells and T cells in mouse splenic lymphocytes was significantly increased in ESMR pretreated mice in vivo. In FSa II cells that received a combination of 0.2 mg/ml of ESMR with X-irradiation exposure, the survival fraction with a dose of 2, 4 and 6 Gy was $0.39{\pm}0.005$, $0.22{\pm}0.005$ and $0.06{\pm}0.007$, respectively. For FSa II cells treated with X-irradiation alone, the survival fraction with a dose of 2, 4 and 6 Gy was $0.76{\pm}0.02$, $0.47{\pm}0.008$ and $0.37{\pm}0.01$. The difference in the survival fraction of the mouse FSa II cells treated with and without ESMR was statistically significant (p<0.05). Conclusion: Treatment with ESMR increased cell viability of mouse splenocytes in vitro and especially the subpopulation of B cells and T cells in splenocytes in ESMR-pretreated mice. However, treatment with ESMR did not increase the level of Th and Tc subpopulations in the thymocytes. Treatment with the combination of ESMR and X-irradiation was more cytotoxic to mouse tumor cells than treatment with X-irradiation alone; this finding was statistically significant.

• Journal of Life Science
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• v.23 no.4
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• pp.510-517
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• 2013

This study was performed to evaluate the antiobesity effect of supercritical fluid extracts (SFC) and marc methanol extracts (SFM) from Cinnamomum verum in 3T3-L1 preadipocytes. In inducing the differentiation of 3T3-L1 preadipocytes in the presence of an adipogenic cocktail, iso-butylmethylanthine (IBMX), dexamathasone, and insulin, treatment with fraction residue SFC and SFM. SFC significantly reduced the mRNA expression of the transcription factor peroxisome proliferator-activate-dreceptor-${\gamma}$ ($PPAR{\gamma}$), the sterol regulatory-element-binding protein-1c (SREBP1c), and the CCAAT enhancer-binding-protein ${\alpha}$ ($C/EBP{\alpha}$) in a concentration-dependent manner. Moreover, SFC markedly down-regulated acyl-CoA synthetase-1 (ASC1), fatty acid synthesis (FAS), fatty acid transport-1 (FATP1), fatty acid binding protein 4 (FABP4), and perilipin. These findings suggest that SFC may be a potential therapeutic adjunct for obesity by targeting the differentiation of preadipocytes, as well as their functions.

• Proceedings of the Korean Journal of Food and Nutrition Conference
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• 2004.07a
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• pp.53-53
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• 2004

버섯류는 항산화, 항암, 항변이원성, 항콜레스테롤성 효과 등의 여러 가지 생리활성 기능을 나타내기 때문에 암 및 성인병에 대한 예방 및 개선효과가 기대되는 좋은 소재라 할 수 있다. 그러므로 본 연구에서는 영지버섯의 생리 기능에 대한 활성을 탐색하고자 영지버섯을 에탄올로 추출하여 항산화효과와 항돌연변이 효과를 측정하였다. MDA에 대한 단백질의 보호효과를 알아본 결과 영지버섯추출물은 MDA의 교차 결합 형성을 31.68％저해하였고 처리농도가 증가할수록 저해율은 증가하였다. (중략)

• Proceedings of the Optical Society of Korea Conference
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• 2003.07a
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• pp.296-297
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• 2003

본 연구에서는 푸리에 변환법에 의한 위상정보 추출 기술을 개발하고, 주파수 영역에서의 창함수 필터에 따른 위상추출 특성을 분석하였다. 푸리에 변환법은 위상이동법과는 달리 정현파 패턴이 투영된 하나의 영상만을 이용하여 3차원 형상정보를 추출할 수 있는 장점이 있다. 획득된 영상은 오일러 공식으로부터 다음과 같이 표현할 수 있다. (중략)

• The Korean Journal of Food And Nutrition
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• v.13 no.4
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• pp.379-382
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• 2000

Conditions of isolation for the red color pigments from the Korean Lithospermum erythrorhizon were investigated and identification of the red pigment was analysed. Non-polar solvents were more effective than water. Especially, 95% ethanol was observed as optimum solvent for the pigments extraction. About 20 minutes at 40$^{\circ}C$ with 95% ethanol was enough for the extraction of the red pigments. The major pigment was analysed as acetylshikonin by TLC, IR, NMR and GC/MS.