• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.5
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• pp.921-927
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• 2002

Inflammation is localized response to foreign substance such as bacteria or in some instance to internally produced substances and has relation with immunity system. The macrophages plays a role in the development of the Iymphohaemopoietic system before and after birth, as well as in the natural and acquired immune responses of adult to immunogens, including infectious agents. NO have been suggested to play an important role in endotoxin-mediated shock and imflammation. In this study, we investigated the effect of Omisodok-eum on the production of NO. The Omisodok-eum inhibited the secretion of NO in LPS-stimulated mouse peritoneal macrophages, without affecting cell viability. The protein level of inducible nitric oxide synlhase(iNOS) in peritoneal macrophages was also decreased by Omisodok-eum. These results suggest that Omisodok-eum suppresses the endotoxin-induced inflammatory responses through inhibiting the production of NO

• Phonetics and Speech Sciences
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• v.1 no.2
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• pp.119-128
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• 2009

Many researchers have argued about the relationship between information structure and intonation. Their results can be summarized in three main points: the intonation of topic and focus in English information structures is implemented as i) a pitch accent, ii) a tune (a pitch accent + (an) edge tone(s)), or iii) a boundary tone. The purpose of this paper is to study various intonational patterns of topic and focus in English information structures, using natural conversations. In this paper, the types of topics and foci are divided, based on contrastiveness. The topics are classified as five non-contrastive and four contrastive topics. The foci are classified as neutral focus, informational focus, and contrastive focus. The results show that the intonation of the topic in English information structures is mainly implemented as a pitch accent, except for the type of the pronoun topic (Lp) which is not implemented as a pitch accent or a tune. However, the intonation of the focus is implemented as a tune in the neutral focus (Fn) and as a pitch accent or a tune in the informational focus (Fi) and the contrastive focus (Fe). In our discussion and conclusion, we suggest that it is not always true that for the meaning of contrast, the topic or the focus is represented as a $L+H^{\ast}$ pitch accent, which has been the main contrastive intonation from earlier studies.

• The Korean Journal of Applied Statistics
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• v.20 no.2
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• pp.409-422
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• 2007

Filtering genes that do not appear to contribute to regulation prior to the statistical analysis of time course gene expression data can reduce the dimensions of data and the possibility of misinterpretation due to noise or lack of variation. In this paper, we compare six different functions for filtering genes with flat pattern under the percentile criterion on an observed sample and that on a bootstrap sample. The result of applying to the yeast cell cycle data shows that the variance function is most similar in both samples.

• Journal of Korean Medical classics
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• v.19 no.3
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• pp.33-46
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• 2006

통과대약물적(通過對藥物的)'승강부심(升降浮沈)'이론화기재방제학적운용방면적연구득출여하결론(理論和其在方劑學的運用方面的硏究得出如下結論): 1. 대약물적(對藥物的)'승강부심(升降浮沈)'대래영향적인소유(帶來影響的因素有), 기미후박지음양(氣味厚薄之陰陽), 한열온경지사기(寒熱溫京之四氣), 산고감신함지오미(酸苦甘辛鹹之五味), 이급약용부위(以及藥用部位), 약물적재질(藥物的材質), 약물적생숙등(藥物的生熟等). 2. 재약성작용상가구분위(在藥性作用上可區分爲), 승부적약성구유소풍(升浮的藥性具有疏風), 산한(散寒), 선폐(宣肺), 투진(透疹), 승양(升陽), 통비(通痺), 최토(催吐), 개궁등작용(開窮等作用), 이침강약성구유통편(而沈降藥性具有通便), 사화(瀉火), 이수(利水), 진정안신(鎭靜安神), 평간개탕(平肝漑湯), 평단(平端), 강역(降逆), 고정(固精), 삽장(澁腸), 지대등자용(止帶等作用). 3. 근거재(根據在), ${\ulcorner}$의학입문(醫學入門) 본초(本草)${\lrcorner}$ 중장결고등인적이론(中張潔古等人的理論), 치풍문적약가귀납위'승'적작용(治風門的藥可歸納爲'升'的作用), 치열문적약가귀납위'심'적작용(治熱門的藥可歸納爲'沈'的作用), 치조문적약가귀납위'강'적작용(治操門的藥可歸納爲'降'的作用), 치한문적약가귀납위'부'적작용(治寒門的藥可歸納爲'浮'的作用), 단시실제상부동적'승강부심'작용시상혼재일기적(但是實際上不同的'升降浮沈'作用是相混在一起的). 4. 재(在) ${\ulcorner}$의학입문(醫學入門)${\lrcorner}$, ${\ulcorner}$의방집해(醫方集解)${\lrcorner}$, ${\ulcorner}$의방고(醫方考)${\lrcorner}$ 중구체응용등약물적승강부심이론(中具體應用等藥物的升降浮沈理論), 내설명료방제적조성원리(來說明了方劑的組成原理), 저일점적용어소유처방(這一點適用於所有處方), 단시주요국한어중기적허약혹심현부교(但是主要局限於中氣的虛弱或心賢不交), 음허화왕등(陰虛火旺等).

• Phonetics and Speech Sciences
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• v.5 no.4
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• pp.185-193
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• 2013

This study investigates dialectal differences in the acoustic properties of Korean lenis, aspirated, and tense stops Seoul Korean (standard Korean) and Yanbian Korean (spoken in the largest Korean Autonomous Prefecture in China). This production study the main acoustic cues that each dialect uses to mark the laryngeal distinction between the three types of Korean stops. Measurements included VOT, and the initial F0 of the following vowel. Data collected from 10 young Seoul Korean speakers, 10 young Yanbian Korean speakers, and 6 older Yanbian speakers. two key findings: First, aspirated and lenis stops are mainly differentiated by F0 in Seoul Korean, and by $H1^*-H2^*$ in Yanbian Korean. Second, there is no VOT merger between lenis and aspirated stops in Yanbian Korean, whereas there is in Seoul Korean. These results are discussed in terms of the phenomenon of VOT shift and the function of F0t is argued that the function of F0 to substitute for VOT difference as a primary cue for the coding of laryngeal contrast can be predicted by the pitch accent system of the language involved.

• Tuberculosis and Respiratory Diseases
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• v.65 no.6
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• pp.541-545
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• 2008

Hypersensitivity pneumonitis (HP) is an immunologically-mediated disease resulting from repeated exposure to sensitizing agents, such as organic dusts or chemicals. Isocyanate is a volatile and highly reactive chemical that is extensively used in the manufacturing of automobiles, upholstery, and polyurethane foam. Occupational respiratory diseases associated with isocyanate, such as bronchial asthma, are well-known. It is thought that HP is one of the rare diseases induced by isocyanate with a very low frequency worldwide. We report a case of HP in an automobile painting sprayer which appeared to be associated with isocyanate.

• The Korean Journal of Applied Statistics
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• v.16 no.2
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• pp.335-349
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• 2003

In this paper, we use Bayesian method for model selection of poisson vs. negative binomial distribution, and normal, double exponential vs. cauchy distribution. The fractional Bayes factor of O'Hagan (1995) was applied to Bayesian model selection under the assumption of noninformative improper priors for all parameters in the models. Through the analyses of real data and simulation data, we examine the usefulness of the fractional Bayes factor in comparison with intrinsic Bayes factors of Berger and Pericchi (1996, 1998).

• Korean journal of food and cookery science
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• v.28 no.2
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• pp.143-148
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• 2012

$Dumebuchu$ ($Allium$ $senescens$ L. var. $senescens$) has a peculiar and long-lasting odor that resembles the flavor of garlic and onions. This study was conducted to examine the volatile compounds of essential oils extracted from $dumebuchu$. The essential oils of $dumebuchu$ were extracted by hydrodistillation using a clavenger-type apparatus and analyzed by GC-MS. A total of 25 compounds were identified in the essential oils from $dumebuchu$. Among sulfur-containing compounds, 4 disulfides and 3 trisulfides were identified. The most abundant sulfur-containing compound was 5-dimethylthiophene (peak area 41.15%) and the second and the third most abundant compound were dipropyl disulfide (18.91%) and propyl allyl disulfide (12.23%), respectively.

• Journal of Korean Medical classics
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• v.13 no.1
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• pp.304-327
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• 2000

This report is closely related to ${\ulcorner}$Simple question Five Qi Anouncement${\lrcorner}$ that you shouldn't take a Hot Taste excessively in case of Qi pathology because a Hot Taste runs to Qi, you shouldn't take a Salty Taste excessively in case of Blood pathology because a Salty Taste runs to Blood, you shouldn't take a Bitter Taste excessively in case of Bone pathology because a Bitter Taste runs to Bone, you shouldn't take a Sweet Taste excessively in case of muscles pathology because a Sweet Taste runs to Muscles, you shouldn't take a Sour Taste excessively in case of Sinews pathology because a Sour Taste runs to Sinews. Also the report mainly describes to relations between Five Tastes and BloodVessel-Organs of human body, to pathological change of a Five Tastes' one-sided diet or taking too much, and to various disease caused by that. And the section is called 'An Essay on Five Tastes', that Five Tastes of food and medicines could make human body either healthy or damaged so you should be careful. This report is divided into two chapter, the first chapter presents to specific diseases according to runnings of Five Tastes, the second chapter shows the pathological process how the human body would change and what kind of disease attacts human body as result of taking Five Tastes. So this section is important remarkably as a viewpoint of food and medicines.

• Korean Journal of Childcare and Education
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• v.15 no.3
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• pp.115-133
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• 2019

Objective: The purpose of the study was to develop a mathematics education program utilizing food to improve the mathematical abilities of 4-year-olds and to analyze the effects of this program on 4-years-olds' mathematical concepts (number and operation, algebra, geometry, measurement, data analysis, and probability). Methods: The study selected 30 4-year-olds from two daycare centers located in K city. The experimental group (N=15) participated in the mathematics education program utilizing food, 10 times for five weeks, while the comparative group (N=15) participated in the seasonal mathematics education program based on the Nuri Curriculum. The activities of this intervention program were designed to cover all domains of Mathematical Exploratory areas in the Nuri Curriculum. For data processing and analysis, pre-test and post-test score differences between the two groups were analyzed through MANCOVA. Results: The experimental group had significantly higher scores on five mathematical concepts compared with the control group. A mathematics education program utilizing food had the positive effect of improving 4-year-olds' mathematical ability. Conclusion/Implications: Mathematic education programs utilizing food are recommended as necessary pedagogical data to develop the mathematical abilities of children in education centers, families, or relating to parenting education.