• Journal of the Korean Society of Food Science and Nutrition
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• v.29 no.5
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• pp.935-942
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• 2000

This study was designed to investigate the effect of flower of Pueraria lobata on liped peroxidation and activities of alcohol metabolic enzymes in alcohol-treated rats. Male Spra gue-Dawley rats were given 25% ethanol (Alcohol), 25% ethanol and 5 mg tectorigenin/kg B.W.(Alc.-Tec), 25% ethanol and 5mg kaikasaponin III/kg B.W. (Alc-Kai). The contents of serum total lipid, triglyceride and phospholipid were increased by ethanol treatment and were lower in the Alc.-Tec and Alc.-Kai group than in the Alcohol group. Decreased serum HDL-cholesterol by alcohol treatment was recovered by tectorigenin and kaikasaponin III. Microsomal cytochrome P-450, aniline hydroxylase and aminopyrine N-demethylase activities were increased by ethanol and were lower in the Alc. Tec and Alc.-Kai group than in the Alcohol group. Activity of hepatic alcohol dehydrogenase was increased by ethanol and was higher in the Alc.-Tec and Alc.-Kai group than in the Alcohol group. Microsomal ethanol oxidizing system activity was higher in Alc.-Tec group than in the other group. No significant difference was found in catalase activity among treatment groups. These data indicate that tectorigenin and kaikasaponin III were effected alcohol metabolic enzyme system and the liver damage associated with chronic ethanol consumption.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.8
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• pp.1139-1147
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• 2014

We investigated whether or not Schisandra chinensis (SC), a traditional herbal medicine, has protective effects against alcohol-induced fatty liver and blood alcohol clearance. Two tests focused on acute intoxication and chronic ethanol treatment were carried out. For the chronic ethanol treatment test, rats were fed ethanol by intragastric administration everyday for 8 weeks to induce alcoholic fatty liver. Ethanol treatment significantly increased blood alcohol concentration at 90 min after acute ethanol intoxication. Compared with the two ethanol-treated groups, rats administered ethanol along with SC extracts showed an approximately 13% increased blood alcohol clearance rate at 360 min. Chronic ethanol treatment significantly increased serum and hepatic triglyceride (TG) levels, and caused fatty degeneration of liver. Ethanol treatment also elevated the serum total-cholesterol (TC) level. However, after feeding of ethanol plus SC extracts, ethanol-induced elevation of hepatic TG levels reversed, whereas elevation of serum TG and TC levels was not observed after treatment with SC extracts. Ethanol treatment significantly increased ${\gamma}$-GT, aspartate aminotransferase, and alanine aminotransferase activities after 8 weeks. Compared with the ethanol-fed group, rats administered ethanol plus SC extracts for 4 weeks showed attenuated fatty degeneration as well as decreased hepatic function test values. SC administration also significantly increased intracellular lipid accumulation in hepatocytes and reduced steatosis score and hepatic TG levels, as measured by biochemical and histolopathological analyses. Our results indicate that the protective effects of SC are accompanied by a significant decrease in hepatic TG levels, thereby suggesting SC has the ability to prevent ethanol-induced fatty liver, by reducing hepatic TG and enzyme levels in alcoholic rats.

• The Journal of the Korea Contents Association
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• v.19 no.12
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• pp.604-614
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• 2019

The purpose of this study is to evaluate the effects of the acceptance commitment therapy program (ACT) on the psychological flexibility, self-compassion, recovery in alcohol dependents. The ACT program contains skills that establish acceptance and willingness, defusion, self-as-context, contact with the present moment, clarifying values, and committed action. This study was intended to enhance the effects on the psychological flexibility, self-compassion, recovery in alcohol dependents with ACT program. Fifteen inpatients with alcohol dependence were participated in the ACT group and the same number of participants were in the both CBT control group and TAU control group. The ACT program was held once a week, eight times, and each session was 90-minute long. Repeated measure of MANOVA and post-hoc were used to compare pre-test mean with post-test and with follow-up test mean. As a result of ACT program, positive changes were assured in the psychological flexibility including acceptance, cognitive defusion, being present, committed action and the increase of self-compassion and of recovery in alcoholics.

• Journal of the Korea Convergence Society
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• v.10 no.4
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• pp.91-97
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• 2019

The aim of this study was to compare effects of oral health education on oral health behavior according to demographic and dental health-related characteristics in inpatient alcoholics. 62 alcoholic male patients were recruited to 32 patients at education group and 30 at non-education group. To search demographic and dental health-related characteristics, the self-administered structured questionnaires were used, and the survey was conducted before and after the oral health education. The oral health education program was consisted of 40 mins theoretical education and individual tooth brushing training once a week for 4 weeks. The oral health education for alcoholic patients had big effects on oral health behavior. And these results indicate that if oral health program was performed systematically in alcohol counseling centers or alcohol hospitals, more oral health promotion effects will appear.

• Korean Journal of Social Welfare
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• v.23
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• pp.151-175
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• 1994

• The Science & Technology
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• v.33 no.8 s.375
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• pp.88-89
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• 2000

• 한국사회복지학회:학술대회논문집
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• 1993.11a
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• pp.195-212
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• 1993

• Journal of Nutrition and Health
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• v.47 no.4
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• pp.277-286
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• 2014

Purpose: The aim of this study was to examine the characteristics of nutrition-related knowledge, dietary habits, and nutrient intakes of alcoholic patients and how nutrition education affects these nutritional behaviors. Methods: Subjects included 37 adult male alcoholic patients who were hospitalized. The nutrition education program consisted of five lessons over a five-week period. An each 80-minute nutrition education program per week was implemented for the alcoholic patients over a five-week period. Both before and after the implementation of nutrition education, their nutrition-related knowledge and dietary habits were assessed and nutrient intakes were investigated. Results: The subjects showed drinking habits of considerably high frequency, a large quantity of alcohol consumption, and preference for soju (a liquor) over beer. They had proper weight, height, and BMI, and came from relatively poor socioeconomic backgrounds with a low-level of self-rated health status and a comparatively high rate of suffering from disease. Mean score of their nutrition-related knowledge and dietary habits was quite low. They consumed less energy, dietary fiber, vitamin C, thiamin, riboflavin, folic acid, Ca, and K, but more Na compared to each Dietary Reference Intake (DRI). After implementing the nutrition education, mean score of nutrition-related knowledge and dietary habits showed significant improvement. In addition, the meeting rate of each DRI of several nutrients was increased significantly, including energy, carbohydrate, dietary fiber, vitamins A, C, and $B_6$, thiamin, riboflavin, niacin, pyridoxine, folic acid, Ca, P, K, Fe, and Zn, while that of Na decreased. Conclusion: The findings of this study indicate that alcoholic patients had various nutritional problems, such as lack of nutrition-related knowledge, bad dietary habits, and insufficient nutrient intakes, however, these problems can be positively modified by implementation of a relatively short-term nutrition education program.

• Korean Public Health Research
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• v.44 no.4
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• pp.1-13
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• 2018

Purpose : The purpose of this study was to explore the subjective experiences of problem drinkers participating in the early intervention program for moderate alcohol drinking. Methods : A qualitative descriptive study design was used. Data were collected through individual interviews with thirteen problem drinkers and analyzed using qualitative content analysis. Results : The experiences of the problem drinkers participating in the early intervention program were derived from four themes and nine sub-themes in terms of awareness, alcohol expectancies, perceived self-efficacy and behavioral change. They participated in programs offered in the workplace, and there were differences in motivation level among individuals, but generally accepted the necessity of the program. Participants who had trust with the program provider were more likely to change drinking behavior. Conclusion : Problem drinkers who participated in the early intervention program showed that it is a useful approach to change the problem drinking behavior by promoting awareness of alcohol-related knowledge, motivation for change through acquiring enough information and acquisition of self-efficacy as a behavior skill. These findings can be used as basic information for implementing and adapting early intervention for prevention of alcoholism in primary health care setting including workplace.

• 한국HCI학회:학술대회논문집
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• 2008.02a
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• pp.823-828
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• 2008

This study set out investigate what kind of changes would be caused to the craving of alcohol dependent patients by stimuli through virtual reality in the preparation stage for drinking refusal training. With regard to stimulation, it included alcohol exposure, a positive situation, and a negative situation on the basis of drinking encouraging situations(social pressure) known as drinking stimulating situations for alcoholics. The purpose of the study is to provide fundamental materials for the development of new training programs to refuse alcohol and for the examination of the possibility of utilizing virtual reality technology as a new treatment and training tool for alcoholics. To this end, a virtual reality program was conducted involving 12 alcoholics admitted to Severance Mental Health Hospital in Gyeonggi province from December 2006 to September 2007. The data was dealt with various statistic analyses such as frequency analysis, Wilcoxon Matched-pairs Signed-Ranks Test using SPSS/WIN 11.5 The analysis results indicate that avatars encouraging drinking caused more craving than just the background, that the scenes with alcohol exposed caused more craving than the scenes with no alcohol exposed, and that there were no significant changes to craving according to a positive or negative situation. The results confirmed that training sessions using virtual reality presented a situation and environment of drinking pressure that's similar to the actual social pressure and that the virtual reality approach had enormous potential as an effective treatment tool when combined with the existing treatment techniques.