• Journal of Biomedical Engineering Research
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• v.8 no.2
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• pp.177-188
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• 1987

Detection of left ventricular boundary for the functional analysis of LV(left ventricle) is obtained using automatic boundary detection algorithm based on dynamic program ming method. This scheme reduces the edge searching time and ensures connective edge detection, since it does not require general edge operator, edge thresholding and linking process of other edge detection methods. The left ventricular diastolic volume and systolic volume were computed after this automatic boundary detection, and these volume data were applied to analyze LV ejection fraction.

• The Korean Journal of Nuclear Medicine Technology
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• v.16 no.1
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• pp.91-95
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• 2012

Purpose: In this study, we evaluated the ejection fraction (EF) according to the difference of patient position in Gated Blood Pool (GBP) scan. Material and Methods: The analysis was performed to 80 patients ($51.2{\pm}17.4$ years old) who examined GBP scan in Department of nuclear medicine, National Cancer Center from March 2011 to August 2011. We divided the patients into two groups; one group received conventional position (raise left arm up supine) and supine position (group 1) and the other group received conventional position and left arm back down supine position (group 2). To observe the change EF according to patient position difference, the image was reconstructed and analyzed by Xeleris (GE, USA). We measured body mass index (BMI) of patients. Result: In group 1, EF error less than 3% occurred at a rate of 72.5% (29 of the 40 patients). In group 2, EF error less than 3% occurred at a rate of 79% (32 of the 40 patients). The patient's BMI did not affect ejection fraction. Conclusion: The EF error of left arm back down supine position closer to conventional position than in supine position shows the results.

• Journal of Chest Surgery
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• v.30 no.6
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• pp.613-616
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• 1997

We present a case of 58-year-old (tamale with dilated cardiomyopathy(DCMP) in whom we performed left ventricular(LV) remodeling surgery(Batista operation) to reduce the left ventricle diameter and improve left ventricular unction. The patient was admitted September 1996 with heart failure NYHA class IV. There was severe orthopnea and peripheral edema. 2-D echocardiography(Echo) showed DCMP with the ejection fraction(EF) I5%, LV end diastolic dimension(LVEDD) 80mm, mitral regurgitation(MR) grade IV, tricuspid regurgitation ('m) grade ll. Preoperative cardiac output(CO) was 1.5/L/min and cardiac index(Cl) was 1.0 L/min/m2. We proceeded with LV remodeling surgery by resection a part of LV lateral wall between both papillary muscle, from the mitral annulus to the LV apex. Size of resected LV wall was 90 $\times$ 100 $\times$ 15 mm. At the mean time, mitral valve and tricuspid valve were repaired. Postoperative 2-D Echo showed the EF 37%, LVEDD 50 mna, trivial MR, no TR. CO was 3.SL/min and Cl was 2.3 L/min/m2. Her fuctional NYHA class was 1.

• Journal of Chest Surgery
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• v.29 no.2
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• pp.191-198
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• 1996

Amrinone is a non-glycosidic, non-adrenergic positive inotropic agent with peripheral and coronary vasodilator effect. It inhibits phosphodiesterase F-III, the cardiac cyclic-AMP specific phosphodiesterase, selectively and potently. In this study, the effects of IV administered amrinone and dopamine were compared in 40 patients who had open heart surgery. Amrinone was administered as a bolus of 1 5~2mglkg for several minutes, followed by continuous infusion at 5~1 Oug/kg/min. The hemodynamic measurements including heart rate, systolic and diastolic pressure, cardiac index, pulmonary wedge pressure, and systemic vascular resistance were recorded immediately for 12~24 hours awl 7th day following operation. In amrinone group, cardiac index increased from 3.73$\pm$1.39 L/min/m2 to 5.44$\pm$2.65 L/min/m2 at the time of posterative 48 hours (n=20, p< 0.05). The decrease in systemic vascular resistance from 1237.5 $\pm$ 637.7 dyne/sec/cm2 to 1000.8 $\pm$ 608.5 dyne/sec/cm2(p<0.05). In Dopamine group, the heart rate increased from 92.1 $\pm$ 13.0/min to 101.0 $\pm$ 13.1/min and the cardiac index decreased from 3.40 $\pm$ 0.50 L/min/m2 to 2.53 $\pm$ 1.15 L/min/m2 at the time of postoperative 12 hours(p<0.05). Systemic vascular resistance increased from 1058.5 $\pm$ 234.6 dyne/sec/cm2 to 1979.7 $\pm$ 759.2 dynelsec/cm2 The comparison of the hemodynamic effects of amrinone and dopamine, both drugs improved cardiac performance. But the administration of amrinone results in a higher cardiac index, diastolic blood pressure and lower systemic vascular resistance than those achieved with dopamine (p<0.05). The uniqueness of the action of amrinone on the heart and its sustained hemodynamic effect suggest it has clinical promise, pos operative care of cardiac surgery

• Journal of Chest Surgery
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• v.40 no.1 s.270
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• pp.45-51
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• 2007

Background: Although echocardiography is usually used for quantitative assessment of left ventricular function, the recently developed 16-slice multidetector computed tomography (MDCT) is not only capable of evaluating the coronary arteries but also left ventricular function. Therefore, the objective of our study was to compare the values of left ventricular function quantified by MDCT to those by echocardiography for evaluation of its regards to clinical applications. Material and Method: From 49 patients who underwent MDCT in our hospital from November 1, 2003 to January 31, 2005, we enrolled 20 patients who underwent echocardiography during the same period for this study. Left ventricular end-diastolic volume index (LVEDVI), left ventricular end-systolic volume index (LVESVI), stroke volume index (SVI), left ventricular mass index (LVMI), and ejection fraction (EF) were analyzed. Result: Average LVEDVI ($80.86{\pm}34.69mL$ for MDCT vs $60.23{\pm}29.06mL$ for Echocardiography, p<0.01), average LVESVI ($37.96{\pm}24.52mL$ for MDCT vs $25.68{\pm}16.57mL$ for Echocardiography, p<0.01), average SVI ($42.90{\pm}15.86mL$ for MDCT vs $34.54{\pm}17.94mL$ for Echocardiography, p<0.01), average LVMI ($72.14{\pm}25.35mL$ for MDCT vs $130.35{\pm}53.10mL$ for Echocardiography, p<0.01), and average EF ($55.63{\pm}12.91mL$ for MOCT vs $59.95{\pm}12.75ml$ for Echocardiography, p<0.05) showed significant difference between both groups. Average LVEDVI, average LVESVI, and average SVI were higher in MDCT, and average LVMI and average EF were higher in echocardiogram. Comparing correlation for each parameters between both groups, LVEDVI $(r^2=0.74,\;p<0.0001)$, LVESVI $(r^2=0.69,\;p<0.0001)$ and SVI $(r^2=0.55,\;p<0.0001)$ showed high relevance, LVMI $(r^2=0.84,\;p<0.0001)$ showed very high relevance, and $EF (r^2=0.45,\;p=0.0002)$ showed relatively high relevance. Conclusion: Quantitative assessment of left ventricular volume and function using 16-slice MDCT showed high relevance compared with echocardiography, therefore may be a feasible assessment method. However, because the average of each parameters showed significant difference, the absolute values between both studies may not be appropriate for clinical applications. Furthermore, considering the future development of MDCT, we expect to be able to easily evaluate the assessment of coronary artery stenosis along with left ventricular function in coronary artery disease patients.

• Journal of the Korean Institute of Telematics and Electronics
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• v.26 no.2
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• pp.132-139
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• 1989

We have designed a real-time Cardiac digital substraction angiography system (C-DSA) and tested the system for the diagnosis of Cardiac patients. The system was developed by interfacing a radiographic angiography system to a computerized motional image analysis system. This new cardiac DSA can perform the real time processing of averaging and subtraction of the 32 image frames to measure the volume changes of the left ventricle after elimination of motional artrifacts, caused by the heart contraction of beats per minute in average. Each frame has a resolution of 512 x 512 pixels and 256 gray levels. Two image data with maximal and minimal volume were moved to the interfaced IBM PC computer system by high speed computer link line for computation of the heart's contraction parameters. First, the boundary of the left ventricule was detected using a dynamic programming of the gray levels, and its volume was computered to determine the parameters, such as the maximal volume of end-diastolic volume (EDV), the minimal volume of end systolic volume (ESV), and ejection fraction (EF).

• Journal of radiological science and technology
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• v.45 no.2
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• pp.151-158
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• 2022

The Cardiac Gated Blood Pool (GBP) scintigram, a nuclear medicine imaging, calculates the left ventricular Ejection Fraction (EF) by segmenting the left ventricle from the heart. However, in order to accurately segment the substructure of the heart, specialized knowledge of cardiac anatomy is required, and depending on the expert's processing, there may be a problem in which the left ventricular EF is calculated differently. In this study, using the DeepLabV3 architecture, GBP images were trained on 93 training data with a ResNet-50 backbone. Afterwards, the trained model was applied to 23 separate test sets of GBP to evaluate the reproducibility of the region of interest and left ventricular EF. Pixel accuracy, dice coefficient, and IoU for the region of interest were 99.32±0.20, 94.65±1.45, 89.89±2.62(%) at the diastolic phase, and 99.26±0.34, 90.16±4.19, and 82.33±6.69(%) at the systolic phase, respectively. Left ventricular EF was calculated to be an average of 60.37±7.32% in the ROI set by humans and 58.68±7.22% in the ROI set by the deep learning segmentation model. (p<0.05) The automated segmentation method using deep learning presented in this study similarly predicts the average human-set ROI and left ventricular EF when a random GBP image is an input. If the automatic segmentation method is developed and applied to the functional examination method that needs to set ROI in the field of cardiac scintigram in nuclear medicine in the future, it is expected to greatly contribute to improving the efficiency and accuracy of processing and analysis by nuclear medicine specialists.

• Journal of Chest Surgery
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• v.30 no.11
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• pp.1077-1082
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• 1997

To assess the early results, risk factors and optimal timing for coronary artery bypass graft surgery(CABG) after an acute myocardial infarction(AMI), we reviewed our 19 patients who underwent CABG within 30 days after AMI, between June 1994 and October 1996. This study excluded 1 patient whose diagnosis was AMI with ventricular septal rupture. 14 of the patients were male and 5 were female. Their ages ranged from 41 to 77 years(mean age, 60.6$\pm$ 10.4 years), and the amount of time between AMI and CABG ranged from 8 hours to 24 days(mean time, 10.6$\pm$6.4 days). There were 11 anteroseptal infarctions and 8 inferior wall infarctions. 11 patients had trsnsmural infarctions and 8 had subendocardial infarctions. Indications of operations were p imary revascularization and postinfarction angina. Three patients required preoperative intra-aortic balloon pump(IABP) support, and 4 additional patients required IABP to be separated from cardiopulmonary bypass. An average of 3.6 $\pm$ 0.6 vessels per patient were bypassed. The early mortality rate for these 19 patients was 5.3% and late mortality rate was 5.5%, 1-year and 2-year actuarial survival rates were 89.5% Univariate analysis of mortality showed that an ejection fraction less than 30% and intraopretative IABP supports were associated with risk factors(p value=0.018 and 0.015 respectively). Age, sex, time to CABG, emergency operations, types and locations of infarctions were not significant. Although our studies have weak p.oints in that there was only a small number of patients and the lack of long-term results, we could conclude that early myocardial revascularization is relatively safe after AMI for those individuals with an ejection fraction greater than 30%.

• Science of Emotion and Sensibility
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• v.12 no.3
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• pp.299-306
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• 2009

In this study, pulse waves were measured at radial artery using non-invasive tonometric pulse pressure measurement system, SphygmoCor(AtCor, Australia), according to subject's posture. Then it was analysed whether the pulse wave parameters, which contain heart activities, change among three different postures (upright stand, sit, and supine). And it was also verified that the pulse wave parameters change among blood pressure level groups(hypotensive, normotensive, and hypertensive). As a results, posture effects were verified in time information of pulse wave rather than amplitude. But some parameters calculated by ratio of two amplitude, such as augmented index(AI) and ratio of central aortic pulse and radial artery pulse, showed significant difference according to postures. In post hoc test, time to the $1^{st}$ and $2^{nd}$ pulse peak(P_$T_1$, and P_$T_2$), ED(ejection duration), and HR(heart rate) showed significant difference among posture groups with each other. In comparison of blood pressure groups, it was verified that the parameters related to amplitude of pulse wave showed significant difference rather than time information.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.5
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• pp.2142-2147
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• 2012

This study is aimed at decreasing wrong diagnosis with corrected EF(Ejection Fraction) of 2D echo cardiography by analysing the physical time-resolution difference between Cine MRI and 2D echo cardiography and applying the corrected EF in 2D echocardiography. From February 2010 to December 2011, among the 110 patients who had undergone both 2D echo cardiography and cine MRI only 37 patient were selected suffering aortic valve regurgitation. ED, ES and SV were measured and EF was calculated in each system while normal ranges of Cine MRI and 2D echocardiography were compared to evauate misdiagnosis rate. The correlation of physical time resolution between 2D echocardiography and MRI was evaluated and the differences were corrected with linear regression coefficient which is derived from linear regression analysis. Blandt-Altman plot was used to evaluate the reliability of corrected 2D echo cardiography EF and compare the error among measured values. The values were compared with MRI normal range and misdiagnosis rate was measured again. As a result, misdiagnosis rates of physical time resolution were measured to be 32.4%(12people) before the correction of EF and 18.9%(7people) after the correction. Also, EF confirmed in Blandt-Altman plot were almost the same with MRI EF. In conclusion, when diagnosing aortic regurgitation disease, simply using 2D echocardiography can easily raise the misdiagnosis rates, therefore considering the MRI machine's physical merits, correcting the time resolution difference is important by calculating time resolution wrong diagnosis would decrease and it is considered to be useful in clinical circumstances.