• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.1
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• pp.615-621
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• 2018

To enhance the energy saving and comfort of indoors, this study performed a stimulation of sound fluctuation, color temperature, and aroma. The experiment with EEG, HRV, and Vibra images was conducted in an environmental test room with a temperature of $25[^{\circ}C]$, relative humidity of 50[RH%], air current speed of 0.002[m/s], and illuminance of 1000[lux]. The stimulation experiment set up different sensory stimulation conditions, such as before exposure, single-sensory stimulation of fluctuation a=1.106 jazz music, single-sensory stimulation of RED color lighting, single-sensory stimulation of scent aroma, and multi-sensory stimulation of fluctuation a=1.106 jazz music, RED color lighting, and scent aroma. After the multi-sensory stimulation of fluctuation a=1.106 jazz music, RED color lighting and scent aroma, the capacity for work and attention were increased, and the stress index and fatigue degree were decreased. In addition, multi-sensory stimulation of fluctuation a=1.106 jazz music, RED color lighting, and scent aroma were effective in maintaining a stable heart and health. In addition, the Vibra image appeared to decrease tension/anxiety and stress. The multi-sensory stimulation of fluctuation a=1.106 jazz music, RED color lighting, and scent aroma help increase the Neuro-energy more than that by no exposure and single-sensory stimulation.

• Journal of Yeungnam Medical Science
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• v.3 no.1
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• pp.279-285
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• 1986

Carbamazepine is a derivative of iminostilbene with carbamyl group and related chemically to the tricyclic antidepressants. Carbamazepine has been introduced for treatment of trigeminal neuralgia. Recently it is used as an antiepileptic agent such as diphenylhydantoin. Antiepileptic drugs are known to affect experimentally induced cardiac arrhythmia and are now widely used clinically for treatment of ventricular tachyarrhythmias, particularly those produced by digitalis intoxication. Steiner et al.(1970) reported that carbamazepine was found to be very effective in converting ventricular tachycardia due to digitalis toxicity to normal sinus rhythm. Clinically bradycardia, complete heart block, ventricular standstill and Adams-stokes attack were reported in the course of carbamazepine treatment. The purpose of this study was to investigate the effects of carbamazepine on the ouabain-induced arrhythmia in vivo. The rabbits of either sex, weighing from 1.6 to 3.2kg were anesthesized by urethane. After the trachea was cannulated, the rabbits were ventilated with room air using a respirator. Drugs were given into polyethylene cannula in the femoral vein. Blood pressure were recorded by physiograph via pressure tranducer connected with the cannula in the femoral artery. EKG were recorded by Physiograph via electrode implanted in both fore leg and left hind leg. The results are summarized as follows; 1. Arrhythmia was induced by continuous infusion of ouabain.($64{\pm}8.8{\mu}g/kg$) 2. Single administration of ouabain($64{\mu}g/kg$) induced arrhythmia which was persisted for 7-8 min. 3. Ouabain induced arrhythmia was restored to normal sinus rhythm by administration of carbamazepine.(The more dosage, the less frequent and the longer duration) 4. Severe bradycardia, A-V block, atrial fibrillation were seen on the EKG after injection of carbamazepine alone. By the above results, it may be concluded that carbamazepine inhibits the ouabain-induced arrhythmia by dose-dependent.

• Science of Emotion and Sensibility
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• v.6 no.4
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• pp.41-49
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• 2003

To inspect how the different sensitivities in BAS(or BIS) modulate on the HRV pattern stimulated by positive or negative affective sound, we measured the electrocardiogram(ECG) of 25 students(male : 14), consisted of 4 groups depending on the BAS(or BIS) sensitivity, during listening meditation music or being exposed to noise. The power spectral density(PSD) of HRV was derived from the ECG, and the power of HRV was calculated for 3 major frequency ranges(low frequency[LF], medium frequency[MF], and high frequency[HF]). We found that the index of MF/(LF+HF), during listening music, was higher significantly in the individuals with a low BIS but high BAS than in the individuals with a low sensitivity in both BIS and BAS. Especially in the former group, there was a tendency that the index was higher during listening music than during being exposed to noise. For individuals with a high BIS, regardless of the BAS sensitivity, the difference of this index values was not significant. From these results we suggest that individuals with a low BIS but high BAS are more sensitive to positive affective stimuli than other groups, and the index of MF/(LF+HF) is applicable to evaluate positive and negative affects.

• Journal of Chest Surgery
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• v.34 no.8
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• pp.583-590
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• 2001

The aim of this study was to compare one-year graft patency after coronary artery bypass grafting without cardiopulmonary bypass(OPCAB) with that of conventional CABG and that of on-pump beating CABG, and to demonstrate any differences in patency of various conduits among the three groups. Material and Method: We analyzed the results of OPCAB cases(group I; n=122) compared with those of conventional CABG cases(group II; n=65) and those of on-pump beating CABG cases(group III; n=19). In group I, coronary angiography(CAG) was performed immediately postoperatively and 1 year after surgery. In group II and III, CAG was performed 1 year after surgery. Graft patency was graded as grade A(excellent), grade B(fair), or grade O(occluded). Result: The average number of distal anastomoses in groups I, II, and II were 3.1$\pm$1.1, 3.7$\pm$0.9, and 3.6$\pm$0.9, respectively. In group I, postoperative CAG was performed in 92%(112/122) of patients before discharge. The patency rate(grade A+B) was 96.4$(162/168) for arterial grafts, and 85.6%(160/187) for saphenous vein grafts(SVG). One-year follow-up CAG was performed in 74%(90/122) of patients. The patency rate was 97.8%(132/135) for arterial grafts, and 67.9%(106/156) for SVG. In group II, one-year follow-up CAG was performed in 65%(42/65) of patients. The patency rate(grade A+B) was 93.5%(43/46) for arterial grafts, and 86.8%(33/38) for SVG. Conclusion: Our results demonstrated that the patency rate of SVG after OPCAB was significantly lower than that of arterial grafts in the early postoperative CAG(p<0.001), and was also significantly lower than those of SVG of group II(p<0.001) and group III(p<0.01) in the postoperative one-year CAG, although there was no significant difference is one-year patency of arterial grafts among the three groups. Our data suggest that a specific perioperative anticoagulant therapy may be advisable in patients undergoing OPCAB with SVG.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2009.10a
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• pp.444-446
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• 2009

현재 대다수의 맥박(또는 심박) 측정 장치는 electrodes와 PPG로 국한되어 있다. 그러나 electrodes는 착용자의 불편감과 수입 의존성에 의한 높은 가격이라는 단점을 가지고 있으며, PPG는 동잡음에 약하다는 단점을 갖는다. 본 논문에서는 PPG와 flexible sensor를 동시 적용하여 상호 작용하게 함으로서 각 센서들의 단점을 보완 해줄 수 있는 하이브리드형의 맥박 측정 장치에 대하여 연구하였다.

• Journal of Veterinary Clinics
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• v.27 no.5
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• pp.569-572
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• 2010

A 4-year-old neutered female Pekingese dog (weighing 3.6 kg) was referred with the primary complaint of exercise intolerance with occasional syncope. Physical examination revealed irregularly irregular heart rhythm with persistent pulse deficits. The 12-lead surface ECG showed a marked sinus arrest with occasional junctional escape beats, indicating a sick sinus syndrome. Permanent transvenous cardiac pacing with a rate-responsive bipolar implantable pacemaker (VVIR type) was performed in the right ventricle. After pacemaker implantation, the clinical signs were remarkably improved. No further syncopal episodes have yet been occurred after implantation.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.10a
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• pp.1822-1825
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• 2015

본 논문에서는 운동 전후 또는 심장 질환과 관련 있는 사용자가 체중을 측정하면서 동시에 심전도 신호를 측정하여 운동 부하에 따른 심장의 활동 상태를 모니터링 할 수 있는 장치를 고안하였다. 이를 위한 방법으로 체중계에 수정된 바이폴라 금속전극을 적용하여 표준사지 측정법을 이용하여 심장활동 신호를 측정할 수 있는 방법을 제안하였다. 체중계에서 심전도를 측정하기 위해 기존의 Ag-AgCl 전극이 아닌 금속 판 형태의 전극을 사용하였으며 이를 위해 입력 임피던스의 설계를 브릿지 형의 AC-Coupling 회로를 통해 높은 CMRR이 유지되도록 설계하였다. 또한 시시각각 변화하는 노이즈를 제거하기 위해 Savitzky-golay filter를 사용하였으며 이를 통해 Baseline wandering 이 제거된 최종 심장활동 신호를 획득하였다. R-peak 검출을 통해 기준신호와의 심박수 및 Sensitivity의 비교평가를 수행하여 이 장치의 성능을 평가한 결과 심박 검출률의 평균 Sensitivity가 97.1%로 나타났다. 동잡음 제거에 대한 알고리즘이 보다 최적화 되어 최종 출력 신호의 안정성이 향상 된다면 체중계를 통한 심박 검출의 가능성과 그 유효성이 충분할 것으로 사료된다.

• Science of Emotion and Sensibility
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• v.10 no.2
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• pp.273-280
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• 2007

The study is to examine the psychophysiological responses evoked by negative emotions(fear and disgust) in children. 47 children(11-13 years old, 23 boys) participated in the study. While the children were experiencing fear or disgust emotion induced by audio-visual film clips, ECG, EDA, PPG and SKT are measured. Emotion assessment scale was used to confirm that emotions elicited by the film clips were significantly noticeable, which was measured self-report. The results turned out to be 100% and 89.4% of appropriate for fear and disgust emotions, respectively. Emotional intensity the children had experienced was rated as 4.05, 4.07 on 1-5 scale based on effectiveness of measurement of fear and disgust emotion. ANS reponses by fear and disgust were significantly between the resting state and emotional state induced. The result obtained from the fear emotion showed significant increases in SCL, NSCR, HR, RSA, RESP and HF. There was a significant difference in SCL and NSCR between the two emotions.

• Proceedings of the Korean Society of Computer Information Conference
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• 2017.07a
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• pp.253-254
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• 2017

본 논문에서는 타인의 도움 없이 자율적으로 환자를 따라다니며 환자의 상태를 주기적으로 주치의에게 전달하는 스마트 링거대를 구현하였다. 기존의 링거대는 환자 혼자 끌고다니며 움직이기에는 여러 가지 불편한 점이 있다. 예를 들면 잠을 잘 때 링거대의 위치를 환자가 직접 옮겨놓고 자야하며, 옮기기도 몸이 불편한 환자 입장에서는 많은 어려움이 따른다. 또 링거액을 다 썼을 때도 간호사에게 직접 가서 말을 해야 하거나, 피가 역류했을 때도 불편한 몸을 이끌고 간호사에게 가야 한다. 이런 여러 가지 불편함을 스마트 링거대를 제작함으로써 링거대의 이동부터 여러 가지 도움이 필요한 상황이 발생 시 간호사에게 연락을 할 수 있도록 하며, 여러 가지 돌발 상황을 대비하여 추가적으로 심박동 및 체온을 측정하여 이상이 발생 할 시 자동적으로 간호사와 보호자에게 연락이 갈 수 있도록 함으로써 병원에서 환자에게도, 간호사에게도 큰 도움이 될 것이라고 사료된다.

• Korean Journal of Biological Psychiatry
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• v.8 no.1
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• pp.20-36
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• 2001

The debate about whether depressive disorders should be divided into categories or arrayed along a continuum has gone for decade, without resolution. In our review, there is more evidence consistent with the spectrum concept than there is with the idea that depressive disorders constitute discrete clusters marked by relatively discontinuous boundaries. First, "depression spectrum", "is there a common genetic factors in bipolar and unipolar affective disorder", "threshold model of depression" and "bipolar spectrum disorder" are reviewed. And, a new subtype of depression is so called SeCA depression that is a stressor-precipitated, cortisol-induced, serotonin-related, anxiety/aggression-driven depression. SeCA depression is discussed. But, there is with the idea that depressive disorders constitute discrete subtypes marked by relatively discontinuous boundaries. This subtypes of depressive disorder were reviewed from a variety of theoretical frames of reference. The following issues are discussed ; Dexamethasone suppression test(DST), TRH stimulation test, MHPG, Temperament Character Inventory(TCI), and heart rate variability(HRV).