• Title/Summary/Keyword: 신생물

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Hypoglycemic Effect of Fermented Soybean Culture Mixed with Mulberry Leaves on Neonatal Streptozotocin-Induced Diabetic Rats (뽕잎 함유 대두발효물이 신생 당뇨유도쥐에 미치는 혈당강하효과)

  • Hwang, Kyo-Yeol;Kim, Young-Hoon;Cho, Yong-Seok;Park, Young-Shik;Lee, Jae-Yeon;Kang, Kyung-Don;Kim, Keun;Joo, Dong-Kwan;Ahn, Duk-Kyun;Seong, Su-Il
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.4
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    • pp.452-458
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    • 2008
  • The effect of fermented soybean culture of Bacillus subtilis MORI mixed with mulberry leaves on the lowering the levels of blood glucose and cholesterol was examined using neonatal streptozotocin-induced diabetic (n-STZ) rats. B. subtilis MORI produces 1-deoxynojirimycin (DNJ), an $\alpha$-glucosidase inhibitor. The content of DNJ of soybean fermented culture mixed with mulberry was higher (4.1$\pm$0.0 mg/g dry base) than that (1.5$\pm$0.0 mg/g) of mulberry. The concentration of 50% inhibition (IC50) against rat intestinal $\alpha$-glucosidase of soybean fermented culture mixed with mulberry was $5.6{\pm}0.1{\mu}g$/mL and that of mulberry was $17.0{\pm}0.5{\mu}g$/mL. Experimental groups of diabetic rats were randomly assigned to normal control group (NC group), diabetic control group (DC group) and three diabetic groups fed with DNJ food product. One of the three diabetic groups was M group (60 mg DNJ food product/kg) (DNJ food product containing 30% mulberry) and the other two were MM-60 group (60 mg/kg) and MM-120 group (120 mg/kg) (DNJ-fortified food product containing 30% fermented soybean culture mixed with mulberry leaves). The glucose in serum was significantly decreased in the MM-60 and MM-120 groups fed with DNJ-fortified food product for 4 weeks, compared with DC group. Total cholesterol and triglyceride in serum were also lower in MM-60 and MM-120 groups than the DC group. These results support that the fermented soybean culture of B. subtilis MORI mixed with mulberry leaves improved the metabolism of blood glucose and lipid in the n-STZ rat model.

Adsorption and Leaching Characteristics of the Insecticide Imidacloprid in Paddy Soils (살충제 Imidacloprid의 논토양 중 흡착 및 용탈 특성)

  • Ihm, Yang-Bin;Kyung, Kee-Sung;Kim, Chan-Sub;Lee, Hee-Dong;Ryu, Gab-Hee;Lee, Jae-Koo
    • Korean Journal of Environmental Agriculture
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    • v.25 no.1
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    • pp.58-63
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    • 2006
  • In order to elucidate the adsorption and leaching characteristics of the insecticide imidacloprid in two types of paddy soils near Suwon, this experiment was carried out with $[^{14}C]$imidacloprid as a radiotracer. In an adsorption study conducted using $[^{14}C]$imidacloprid in 2 test soils, the adsorption coefficient was higher in soil A $(K_f\;2.6)$ than that in soil B $(K_f\;1.7)$. As calculated from Freundlich constant, distribution coefficients and half lives in soils, GUS indices showed low leachabilities of imidacloprid treated on the paddy soils into the groundwater. The amount of imidacloprid leached from the soil columns during the 4 weeks of leaching was less than 2% of the originally treated $^{14}C$. In the leaching test the amounts of $^{14}C$ activities distributed in the soil layer of 0-10 cm were more than 80% of the originally tented $^{14}C$ and those in rice plants were less than 3% of the originally treated $^{14}C$, suggesting that imidacloprid has very low teachability and bioavailability.

Mantle Source Lithologies of Late Cenozoic Basaltic Rocks and Two Varieties of Enriched Mantle in the Korean Peninsula (한반도 신생대 후기 현무암의 근원 맨틀 암상과 두 종류의 부화 맨틀)

  • Choi, Sung Hi
    • Korean Journal of Mineralogy and Petrology
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    • v.35 no.3
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    • pp.183-197
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    • 2022
  • Geochemical data, including Sr-Nd-Pb-Mg-Zn isotopes, reported on the late Cenozoic intraplate basaltic rocks in the Korean Peninsula (Mt. Baekdu, Jeongok, Baengnyeong Island, Pyeongtaek, Asan, Ganseong, Ulleung Island, Dok Island, and Jeju Island) are summarized to constrain their mantle source lithologies, and the nature of mantle end-members required. In the Sr-Nd isotope correlation diagram, Jeju basalts plot in the field of EM2-type oceanic island basalts (OIB), while the other basalts fall in the EM1-type OIB field. In Pb-Pb isotope space, Jeju basalts show a mixing array between Indian MORB and EM2 component, whereas the other basalts display an array with EM1 component. The Korean basalts were derived from a hybrid source of garnet lherzolite and recycled stagnant slab materials (eclogite/pyroxenite, pelagic sediments, carbonates) in the mantle transition zone. The EM1 component could be ancient (~2.0 Ga) K-hollandite-bearing pelagic sediments that were isolated for a long period in the mantle transition zone due to their neutral buoyancy. The EM2 component might have been relatively young (probably Pacific slab) and recently recycled clay-rich pelagic sediments. Eclogite and carbonates are unlikely to account for the EM components, but they are common in the mantle source of the Korean basalts.

Analytical Psychology-Based Interpretation of a Russian Fairy Tale Entitled "Seven Stars" (러시아 민담 '일곱 개의 별'에 대한 분석심리학적 해석)

  • Myeong-Sook Hwang
    • Sim-seong Yeon-gu
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    • v.30 no.1
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    • pp.31-66
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    • 2015
  • A study on a Russian fairy tale entitled "Seven Stars" was conducted from the perspective of analytical psychology. The plot goes as follows. Once upon a time, a village in Russia was suffering from severe drought. Villagers were dying of thirst, and crops were withering day by day. One night, a little girl left their house carrying a wooden dipper to find water for her sick mother by herself. However, water was nowhere to be found. She felt tired and fell asleep. When she woke up, the moon was already over her head, and the dipper had been filled with water. On her way home to give the water to her mother, she found a dog lying on the ground. The dog was also dying of excessive thirst, so she gave the dog a handful of water. Then the wooden dipper suddenly turned into a silver dipper. When she had finally arrived home and her mother has drunk the water, the silver dipper changed into a golden dipper. At that moment, an old man showed up and asked for water. The little girl gave him water. When the old man stared at the water, she realized that there were seven diamonds twinkling like stars in the dipper. The water never ran out. Surprisingly enough, the seven diamonds suddenly soared up into the sky and eventually formed a constellation of the Big Dipper. The water was shared with the other villagers who, then, recovered their strength. The severe drought came to an end, and the villagers danced together with joy. In this fairy tale, the severe drought symbolizes devastation caused by a unidirectional stream of consciousness while the little girl represents a new function, which shows the value of women who can heal and restore from that devastation. Symbolized in a fairy tale character such as 'a daughter' or 'a little girl', the new function eventually reaches up to the value which leads and affects the group as well as individuals. To conclude, this new function represents the unconscious process whose role is to revitalize the maternity and resolve the problems posed to a group as well as individuals.

Exmination of Anti-Obesity Effect of Regional Special Natural Products of Anthrisci radix, Psoraleae semen, Siegesbeckiae herba and Corni fructus (지역 특산 천연산물 전호, 파고지, 희첨 및 산수유의 항비만효과 규명)

  • Shin, Jin-Hyuk;Cha, Gu-Yong;Kim, Hui-Jin;Hwang, Jae-Ho;Han, Kyeong-Ho;Seo, Hyo-Jin;Shin, Tai-Sun;Oh, Suk-Jung;Kim, Jong-Deog
    • KSBB Journal
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    • v.24 no.6
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    • pp.549-555
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    • 2009
  • 4 kinds of Regional Special Natural Products (RSNPs), such as Anthrisci radix, Psoraleae semen, Siegesbeckiae herba and Corni fructus were examined to verify for anti-obesity effect. $PPAR\gamma$ (peroxisome proliferator-activated receptor $\gamma$) from 3T3-L1 cell concerning adipocyte differentiation was suppressed by different concentraton of 4 RSNPs with western blot, when treated RSNPs' extract and MDI (IBMX, Dexamethasone, Insulin) at the same time. Also, SREBP-1 (Sterol regulatory element binding protein) controlling lipogenesis and $PPAR\gamma$ expression levels were reduced by these 4 RSNPs' extract, when these chemicals after differentiation of 3T3-L1 cell. And lipid droplets were reduced by 7.5%, 14.4%, 18.3% and 30% at different concentration of Anthrisci radix from Oil Red O staining. Also, it was reduced by 2%, 4.9%, 9.3% and 38% at different concentration of Psoraleae semen. For Siegesbeckiae herba, it was inhibited by 1.4%, 6.4%, 16.4% and 30.1%, respectively. And Corni fructus was also showed by 0.9%, 6.3%, 13.7% and 33% at same concentration of Siegesbeckiae herba. These 4 kinds of RSNPs were expected for a useful material for anti-obesity materials.

Primary Malignant Cardiac Lymphoma in Right Atrium - A case report- (우심방에 발생한 원발성 악성 림프종의 수술적 치험 - 1예 보고 -)

  • Choi, Won-Suk;Han, Il-Yong;Jun, Hee-Jae;Lee, Yang-Haeng;Hwang, Youn-Ho;Cho, Kwang-Hyun
    • Journal of Chest Surgery
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    • v.41 no.3
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    • pp.369-372
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    • 2008
  • A primary malignant lymphoma that originates in the heart is extremely rare. A 68-year-old male patient was admitted due to aggravated dyspnea. After echocardiography and chest computed tomography evaluation, a huge mass in the right atrium and the right ventricle was detected. We decided to perform emergency surgery due to a high risk of infarction and hemodynamic disturbance. After the near total removal of the huge mass in the right cardiac chamber, the interatrial septum and antero-lateral part of the right atrium were reconstructed by the use of a bovine pericardial patch. The final pathological diagnosis was a primary malignant lymphoma. The patient and his guardians refused chemotherapy (including radiotherapy), and the patient was discharged to his home, where the prognosis was hopeless.

Surgical Treatment of Mediastinal Neoplasms (종격동 신생물의 수술적 치료)

  • Park, Kyung-Taek;Ryoo, Ji-Yoon;Kim, Yeon-Soo;Kim, Chang-Young;Chang, Woo-Ik
    • Korean Journal of Bronchoesophagology
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    • v.13 no.2
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    • pp.34-39
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    • 2007
  • Background: The mediastinum is the anatomic space which is restricted and the clinical aspect varies according to location, size and type of neoplasm. Diagnostic and therapeutic approaches to mediastinal neoplasms have changed over and over. We presented our recent therapeutic experiences with these neoplasms. The object and method: The 36 patients were treated in operation from 2000 until 2006. The male patients were 20 and the female patients were 16. Age of the patients ranged from 5 to 70, and the median age was $46.4{\pm}21.9$. The child patients were two. Result: The most prevalent anatomic distribution of the neoplasm was anterosuperior mediastinum. The most common neoplasm was thymoma, followed by thymic cyst, teratoma, ganglioneuroma. The complete excison of neoplasm was accomplished in 96% of patient group except thymoma patient group. One patient underwent total thymectomy, and the other 12 patients underwent extended thymectomy from 13 thymoma patient group. In the malignant neoplasm, 7 patients were received additional treatment after operation. There was short-term death of 1 person and late death of 1 person. Conclusion: Our results except clinical manifestation are compared favorably with other reports. Surgery is the management of choice for patients with mediastinal neoplasm and early curative resection is considered to optimize clinical outcome for patients.

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Synchronous Mucoepidermoid Carcinoma of Parotid Gland and Unicentric Cervical Cathleman's Disease : A Case Report (점액표피양 암종과 동반된 경부 캐슬만 병 1예)

  • Noh, Min Ho;Bae, Kong Geun;Ban, Myung Jin;Park, Jae Hong;Lee, Seung Won;Park, Ki Nam;Kim, Jae Wook;Koh, Yoon Woo
    • Korean Journal of Head & Neck Oncology
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    • v.31 no.1
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    • pp.14-17
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    • 2015
  • Castleman's disease is an uncommon lymphoproliferative disorder. The disorder can be classified based on histological subtype, such as hyaline vascular type, plasma cell type, and mixed type, and can also be clinically divided into either unicentric or multicentric type. Its exact pathophysiology is not clearly identified. The unicentric type is able to be treated by surgical resection. However, there is no standard treatment modlity for the multicentric type. Treatment of multicentric type includes anti-cancer chemotherapy and radiation therapy. Recently, authors have experienced a rare case of unicentric type of Castleman's disease accompanying a mucoepidermoid carcinoma of parotid gland and report a case which is discussed with references.

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A case of thyroid malignant solitary fibrous tumor (갑상선에 발생한 악성 고립성 섬유종양 환자 1례)

  • Song, In Sik;Joo, Jae Woo;Lim, Kang Hyun;Choi, Jung Woo;Kim, Young Sik;Oh, Kyung Ho;Kwon, Soon Young
    • Korean Journal of Head & Neck Oncology
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    • v.33 no.2
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    • pp.59-62
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    • 2017
  • Solitary fibrous tumor (SFT) is an uncommon spindle cell neoplasm that is usually presented as a pleural origin localized tumor. There are few cases, found in thyroid. Twenty six cases found in thyroid have been reported since 1993, and two of these were malignant. We report another malignant case in this study; a 55 years old man visited out-patient clinic due to palpable mass of anterior neck, and pathologically diagnosed as malignant SFT of thyroid after surgical resection. In this study, we focus on the clinical features of this uncommon disease along with other literature reviews.

Radiologic Evaluation for Differentiating Benign from Malignant Solitary Pulmonary Nodule (고립성 폐결절에서 양, 악성 감별을 위한 화상적 고찰)

  • 박재길;사영조;정정임
    • Journal of Chest Surgery
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    • v.36 no.12
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    • pp.943-951
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    • 2003
  • We are now detecting an increasing number of solitary pulmonary nodules (SPNs) that are difficult to diagnosis. The purpose of this study was to evaluate the useful radiologic findings for differentiating benign from malignant pulmonary nodules. Material and Method: The high-resolution CT (HRCT) findings of SPNs smaller than 3 cm in largest diameter were evaluated in 134 patients with malignant and benign nodules in regard to internal structures, margin characteristics, and surrounding parenchymal responses. Result: The nodules with the area of ground-glass attenuation (GGA) greater then 50% were noted in adenocarcinoma, inflammatory lesions and some of metastatic tumors, and the lesions greater than 90% were noted only in adenocarcinoma. The area of GGA in non-adenocarcinoma, benign tumors and tuberculomas were less than 50%, and mainly less than 10%. The findings of air bronchogram, spiculation, lobulation, vascular involvement, and pleural indentation were some noted at every types of malignant tumors, but especially high over than 30% in adenocarcinomas. Conclusion: Most peripheral lung adenocarcinomas form a characteristic radiologic findings especially in HRCT. Evaluation of these findings would be helpful in differentiating between lung cancer, especially adenocarcinoma, and other lesions.