• Tuberculosis and Respiratory Diseases
• /
• v.50 no.3
• /
• pp.300-309
• /
• 2001

Background : Sepsis is a clinical syndrome characterized by a systemic inflammatory and hemodynamic response to severe bacterial infections that involve various mediators. Endothelin (ET)-1, a potent vasoconstrictor is associated with mu1tiple organ failure, and interleukin (IL)-8, a proinflammtory cytokine, plays a major role in neurophil activation. Both have been reported to be useful parameters in the clinical assessment of sepsis. The levels of ET-1 and IL-8 in the blood were measured in patients with sepsis, and the correlation of both parameters and their relationship with the clinical data was assessed. Methods : 19 sepsis patients and 17 controls were studied. Blood samples of the sepsis patients were drawn in day 1, 3, 7, and 14. The APACHE III scores were calculated in concurrent days. The ET-1 and IL-8 levels were measured using immunoassay methods. Results : The ET-1 levels of patients with sepsis were significantly higher than in the controls. In patients with sepsis, non-survivors had higher ET-1 levels than survivors on day 1 and 7, and patients with shock also had higher ET-1 levels than normotensive patients on admission. The ET-1 levels were significantly correlated with the creatinine levels on day 1, 7, and 14. The IL-8 levels showed a significant correlation with the ET-1 levels on day 14. Conclusion : ET-1 was found to be closely related with the clinical outcome, shock, and renal failure, and showed a correlation with IL-8. These mediators can be considered not only to play pathophysiologic roles but also as useful parameters in the clinical assessment of sepsis.

• Journal of IKEEE
• /
• v.18 no.4
• /
• pp.471-477
• /
• 2014

In this paper, we propose a low-cost license plate recognition system based on smart cam system using Android. The proposed system consists of a portable device and server. Potable device Hardware consists of ARM Cortex-A9 (S5PV210) processor control unit, a power supply device, wired and wireless communication, input/output unit. We develope Linux kernel and dedicated device driver for WiFi module and camera. The license plate recognition algorithm is consisted of setting candidate plates areas with canny edge detector, extracting license plate number with Labeling, recognizing with template matching, etc. The number that is recognized by the device is transmitted to the remote server via the user mobile phone, and the server re-transfer the vehicle information in the database to the portable device. To verify the utility of the proposed system, user photographs the license plate of any vehicle in the natural environment. Confirming the recognition result, the recognition rate was 95%. The proposed system was suitable for low cost portable license plate recognition device, it enabled the stability of the system when used long time by using the Android operating system.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.19 no.1
• /
• pp.109-114
• /
• 1997

Malignant hyperthermia is a hypermetabolic, fatal syndrome triggered by anesthetic drugs that occurs frequently in genetically susceptible persons. It is characterized by tachycardia, rapidly increasing temperature, skeletal muscle rigidity, respiratory and metabolic acidosis, cyanosis etc. It has been noted that the majority of cases of malignant hyperthermia are fatal unless early diagnosis and treatment are performed. Thus, the accurate prediction of preanesthetic susceptibility and early diagnosis of malignant hyperthermia is necessary to appropriate treatment. Dantrolene sodium has been shown to be effective in the prevention and treatment of malignant hyperthermia. We experienced a case of malignant hyperthermia, which is presented of a 32-year-old healthy male patient in whom a orthognatic surgery was performed under $O_2-N_2O$-enfl-rane anesthesia with induction by pentobarbital and succinylcholine. We discuss this case with reviewing the history, incidence, etiology, pathophysiology, clinical signs & biochemical changes, prevention & treatment.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2011.05a
• /
• pp.85-85
• /
• 2011

홍수기에 안전하고 정확한 유량측정을 통하여 물관리에 필요한 기초수문자료를 확보하고자 한국수자원공사에서 1993년도부터 홍수유량측정기술 확보를 위한 연구를 시작하였다. 그간의 연구성과를 바탕으로 1999년도에 하천의 유속을 비접촉식으로 측정할 수 있는 홍수용 전자파표면유속계를 개발하여 특허등록하였고 그와 동시에 이의 상품화를 추진하여 2010년도까지 75대를 보급하여 실무에서 이용하고 있다. 이동식인 홍수용 전자파표면유속계를 바탕으로 2001년도에는 고정식 실시간 홍수유량측정측정시스템을 개발하여 특허등록하였고, 이 시제품을 현재 용담 수자원시험유역의 동향지점에서 시험운영하고 있다. 또한, 현장 유량측정실무자들의 홍수용 전자파표면유속계 개선요구에 따라 편각용 전자파표면유속계 시제품을 개발하였으며, 이는 임의의 한 지점에 설치한 한 대의 장비로 좌우 여러 측선의 유속을 동시에 측정할 수 있는 다점 측정기능을 갖도록 성능을 개선하였다. 이에 따라 홍수시 유량측정에 소요되는 시간이 줄어들어 신속하게 유량측정을 완료할 수 있는 계기를 마련하였다. 이와 더불어 유속측정 범위를 확장하여 홍수시의 고유속 뿐만 아니라 0.5 m/s 이하의 저유속까지 측정할 수 있는 범용 전자파표면유속계의 시제품을 추가로 개발하였다. 이 장비는 최저유속 0.03 m/s의 측정을 실내시험을 통하여 입증하였다. 범용 전자파표면유속계는 상품화 시제품의 개발을 목표로 기존 시제품의 현장시험을 통하여 현장적용상의 문제점에 대한 해결에 주력하였다. 첫째, 평갈수용 전자파표면유속계의 사용편의를 개선하기 위하여 소형화 및 경량화를 추진하였고, 이를 위하여 사용주파수를 기존의 10 GHz에서 24 GHz로 변경함으로써 $35{\times}35\;cm$ 크기의 기존안테나를 $22{\times}22\;cm$ 크기로 소형화하였으며 송수신부의 무게는 기존 18 kg에서 3.3 kg으로 혁신적으로 줄이는데 성공하였다. 이를 위하여 안테나는 기존의 반사형안테나에서 도파관슬롯배열안테나로 변경하였다. 둘째, 측정값의 안정화를 위하여 안테나의 특성을 개선하여 부엽(side-lobe) 레벨 30 dB 이하 그리고 전후방비(front-back ratio) 50 dB 이하로 개선하여 안테나가 지향하는 방향 이외의 위치에서 반사되는 불필요한 신호를 줄였다. 또한 적응형 이득제어(adaptive gain control)기법의 채택으로 미소 신호에 대한 안정적 측정 및 과다 신호에 대한 능동적 감쇄를 할 수 있도록 시스템을 구성하여 전 유속범위에 대한 안정적 측정을 가능토록 설계 및 제작하였다. 셋째, 자가점검 기능을 탑재하여 유속측정 전에 기기의 상태에 대한 self test기능을 통하여 측정자가 기기의 상태를 사전에 파악 가능토록함으로써, 기기 오작동에 대한 능동 대처할 수 있도록 하였다. 이외에도 저전력 회로설계를 통하여 배터리 사용시간을 확장하였고, 기존의 전자파표면유속계가 가지고 있던 방습 및 방수에도 내성을 갖는 제품으로 설계하였으며 스마트기기를 이용한 무선측정 및 세련된 디자인 등 사용자의 요구사항을 충분히 반영하였다.

• Clinical and Experimental Pediatrics
• /
• v.45 no.12
• /
• pp.1540-1545
• /
• 2002

Purpose : Vesicoureteral reflux(VUR) is defined as a retrograde flow of urine from the bladder into the upper urinary tract. It has been shown to predispose patients to hypertension, renal scarring, and end-stage renal failure if not recognized and treated. The observation that VUR occurs in siblings of children with reflux at a significantly higher rate than the general pediatric population has been recognized for many years and VUR was detected in 26% to 51% of siblings of patients with VUR. The purpose of this study is to determine the incidence of VUR in asymptomatic siblings of children with VUR and to see if this form of screening would be practical. Methods : We retrospectively reviewed the records of 28 patients with VUR and their siblings. The total number of asymptomatic siblings investigating VUR were 28 persons. All patients and siblings were evaluated for VUR by a voiding cystourethrography and all patients and siblings with VUR were performed $^{99m}Tc$ 2,3-dimercaptosuccinic acid renal scan. Results : A total of 28 patients(14 boys, 14 girls) with VUR were studied; the mean patient age was 2.7 years(range 1 month to 8.4 years). The total number of asymptomatic siblings investigating VUR were 28 persons(17 boys, 11 girls) and the mean age was 3.3 years(range 2 months to 7.4 years). Renal scar was detected in 20 of 28(71.4%) patients with VUR. VUR was noted in three of 28(10.7%) siblings and renal scar was detected in one of three siblings with VUR. Conclusion : In this study, the predictive value of a positive family history alone in identifying VUR was 10.7%. This incidence suggests more investigation of asymptomatic siblings and continued study of this group of patients at risk is needed for clarifying the family screening of patients with VUR.

• Journal of the Korea Fashion and Costume Design Association
• /
• v.21 no.4
• /
• pp.43-54
• /
• 2019

This study analyzed the casula wearing by Catholic priests. By understanding various applications of the priests' wearing of casula, we can understand the meaning of wearing casula, situational judgment, and the role and status of priests. Ultimately, the Catholic symbol and meaning of the casula can be found. The purpose of this study is to examine the basic setting of the casula, the setting according to the status of the priest, and the origin of the casula. Second, this study to understand the design of the pattern shown in the casula. The patterns containing the symbol and the liturgical period were examined, and the method of making the pattern design was considered. Third, various symbols appearing in examples of priests' rituals were considered and analyzed. The method of this study was to utilize various pictures acquired during interviews with priests and nuns and to perform content verification. As a result of this study, the aspects of form, color, and pattern were shown through the wearing of casula during various situations. First, the morphological symbols appearing in the rituals are the simplified casula that hangs on the stola on the top of the alb and the symbols of the form according to the priest's status. In the liturgy, the casula is put on the outermost side as for basic wearing, but in the case of celebration or the attendance at celebrations other than the liturgy, it is the same as simplified wearing. Second, in terms of the symbol and color, the basic colored casulas were worn to match the time and character of the liturgy, and in addition, on the priests' ordination ceremony and celebration day the priests wore white casulas. Third, the symbol of the pattern used in the casula was a Cathoric pattern according to the period in the basic casula wearing of the liturgy. In addition, the patterns were produced by combining the patterns and meaning of the priests that were used in the casulas of the priests' ordination ceremony. The design of the pattern used in the beatification mass casula and the Mass of Peace casula during the Pope's visit to Korea in 2014 used the same motif as the Pope's design, but the simplified pattern was produced for the casula of the Cardinal and bishops. Through this, it is possible to understand the situation where a morphological symbol appears due to a distinction according to the role and status of the priest. This shows that the symbols that appear are the cross and should also consider the complexly, shape, color, and pattern.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.17 no.2
• /
• pp.542-548
• /
• 2003

The present study was aimed to investigate whether glycyrrhizin, which is the major component of Glycyrrhiza uralensis, has an antioxidant effect and regulatory effect on Na,K-ATPase in gentamicin-induced acute renal failure (ARF) rats . It is well known that reactive oxygen species (ROS), such as superoxide anion and hydroxyl radical, are main pathophysiological factor in gentamicin-induced ARF. Glycyrrhizin showed potent in vitro antioxidant activity, especially superoxide scavenging activity, in a dose-dependent manner. Plasma lipid peroxide level was restored to normal level by oral administration of glycyrrhizin (200 mg/kg) in the gentamicin-induced ARF rats. The expression of Na,K-ATPase α1 subunit was restored in the gentamicin-induced ARF rats by administration of glycyrrhizin, whereas β1 subunit was not restored. The renal functional parameters including urine volume, cleatinine clearance, urine osmolality, solute-free water reabroption were also partially restored in gentamicin-ARF rats by administration of glycyrrhizin. Taken together, the amelioration of renal functions and the expression of sodium pump by administration of glycyrrhizin in the gentamicin-induced ARF was appear to be mediated by the scavenging of ROS.

• Childhood Kidney Diseases
• /
• v.1 no.2
• /
• pp.123-129
• /
• 1997

Purpose : The Childhood Steroid Resistant Nephrotic Syndrome (SRNS) has a poor prognosis and there has been no effective therapy against SRNS of children. In 1990, Mendoza have reported that methylprednisolone pulse therapy was effective against SRNS of children. But in 1992, Waldo have reported that methylprednisolone pulse therapy was not as effective as in the report of Mendoza. So, retrospectively, we have studied 20 korean children with SRNS to evaluate the effect of methylprednisolone pulse therapy, Methods : Mothylprednisolone pulse therapy were given to 20 korean children with SRNS who admitted to Seoul National University Hospital from 1990 to 1995 and follow up was done Results : 1) During methylprednisolone pulse therapy, remission of nephrotic syndrome was induced in 45% of patients. 2) during follow up after the end of methylprednisolone pulse therapy, remission of nephrotic syndrome was maintained in 45% of patients. 3) 25% of patients has progressed to chronic renal failure. Conclusion : We think that the methylprednisolone pulse therapy is a effective therapy against SRNS of children with the 45%, remission rate of of SRNS in Korean Children

• Childhood Kidney Diseases
• /
• v.12 no.1
• /
• pp.99-104
• /
• 2008

Microscopic polyangiitis(MPA) is a systemic necrotizing vasculitis that involves many organ systems including the skin, joint, kidneys, and lungs. In spite of early diagnosis and intensive care, the five-year actuarial patient and kidney survival rates are 65% and 55%. We experienced a case in 7-year-old girl of microscopic polyangiitis presenting with rapidly progressive glomerulonephritis which was confirmed by renal biopsy and positive serum perinuclear antineutrophil cytoplasmic autoantibodies(p-ANCA). The diagnosis of patients first renal biopsy was MPA, p-ANCA-associated crescentic glomerulonephritis. The patients second renal biopsy was done 5 years 6 months later since first renal biopsy, and pathologic diagnosis was chronic sclerosing glomerulonephritis, advanced, due to MPA. We began methylprednisolone pulse therapy, combined with a low dose of cyclophosphamide and plasmapheresis therapy. ACE inhibitor, angiotensin II receptor blocker, and cyclophosphamide were used until now and the patients current age is 14 years old. On admission, the patients laboratory findings showed BUN 117 mg/dL and Cr 2.3 mg/dL, while on the hospital day BUN and Cr values fell to 20.8 mg/dL and 1.6 mg/dL. But renal function was progressed to chronic failure with latest laboratory data BUN 51.7 mg/dL and Cr 3.2 mg/dL. ACE inhibitor, angiotensin II receptor blocker and small dose of immunosuppressant with close observation is the key to maintain the patient survival.

• Childhood Kidney Diseases
• /
• v.12 no.1
• /
• pp.70-77
• /
• 2008

Purpose: Urinary tract infections(UTIs) are not uncommon findings in febrile pediatric patients and approximately one third of patients with UTI may have renal scars. This research was intended to establish the relationship between duration of fever and renal scars. Methods: The medical records of 143 patients were reviewed retrospectively. Inclusion criteria were as follows: 1) fever as defined by an axillary temperature $\geq37.5^{\circ}C$, 2) accurate history of fever duration and the use of antibiotics 3) no previous history of UTI and 4) positive urine culture. We observed whether the longer fever duration could be associated with the development of initial renal defects and subsequent renal scars, increased C-reactive protein(CRP), leukocytosis and the presence of vesicoureteral reflux(VUR). Results: 1) Patients with longer fever duration after antibiotics showed more frequent initial renal defects(P=0.014). However, fever duration before antibiotic use was not associated with the development of initial renal defects(P=0.244). 2) Incidence of renal scar increased with fever duration before antibiotic use(P=0.006) and fever duration after antibiotic use(P=0.015). 3) CRP correlated with the fever duration after antibiotic use(r=0.287, P=0.003). 4) There was no relationships between fever duration and VUR(P>0.05). Conclusion: Our data suggest that fever duration before/after antibiotic use is significantly associated with the increased development of renal scars in pediatric UTI.