• Title/Summary/Keyword: 신경섬유종

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Multiple External Carotid Artery Aneurysms with Neurofibromatosis - Case Report - (신경섬유종을 동반한 다발성 외경동맥 동맥류 - 증 례 보 고 -)

  • Pyo, Sae Yeong;Kim, Moo Seong;Sim, Hong Bo;Lee, Sun Il;Jung, Yong Tae;Kim, Soo Chun;Sim, Jae Hong
    • Journal of Korean Neurosurgical Society
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    • v.29 no.9
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    • pp.1248-1254
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    • 2000
  • Multiple external carotid artery aneurysms with neurofibromatosis are rare. Trauma is the primary cause in the development of aneurysms of the external carotid artery. A 39-year-old female patient was referred to the emergency room because of a headache and a huge lump over the left temporo-parieto-occipital region. The physical examination revealed a huge round mass, $5{\times}15{\times}18cm$, in the left temporo-parieto-occipital region and low set left ear and multiple caf au lait spots in trunk and extremities. The external carotid artery angiography demonstrated multiple aneurysms arising from the superficial temporal artery and occipital artery. A MRI showed a huge hematoma on temporo-parieto-occipital region and postauricular mass suggested of subcutaneous neurofibroma. Embolization followed by surgical resections of those aneurysms and neighboring mass were performed and good result was obtained. We report our case with review of literature.

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A Case of the Solitary Neurofibroma at the Median Nerve -Ultrastructural Study- (정중신경에 발생한 신경섬유종 치험례 -초미형태학적 관찰-)

  • Ihn, Joo-Chul;Ahn, Jong-Chul;Kim, Sae-Dong;Ahn, Myun-Whan
    • Journal of Yeungnam Medical Science
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    • v.1 no.1
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    • pp.199-206
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    • 1984
  • With respect to the histogenesis of the neurofibroma, there are many controversies, since von Recklinghausen postulated that neurofibromas are mainly fibrous tumors arising from the connective tissue of the nerve sheaths. According to the recent studies through the electron microscope, the neoplastic perineurial cells are regarded as the main components of the tumor. So, the neurofibroma enucleated from the median nerve at the level of proximal arm without resulting neurologic sequale was examined through the light- and electron microscope. Ultrastructurally, this tumor is composed of the perineurial cells, fibroblasts, and collagen fibers. The predominant perineurial cells show distinct basal lamina, and contain abundant microfilaments.

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A Case Report of Head and Neck Neurofibroma Cured with Transitional Flap (국소피판으로 치료한 $6{\times}7cm$ 크기의 두경부 신경섬유종 1례)

  • Do Jae-Woon;Park Sang-Woo;Jeong Joon-Hun;Kang Tae-Woo
    • Korean Journal of Head & Neck Oncology
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    • v.22 no.1
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    • pp.36-39
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    • 2006
  • The Neurofibroma is a benign neoplasm originating from neural tissue such as Schwann cell, fibroblast and peripheral fibroblast, which rarely converts to malignancy. About 25-45% of neurofibroma are located in head and neck, and the most common sites are lateral cervical region and mouth. Because of its high vascularity and invasion to the adjacent organs, surgical resection may be confronted and limited, moreover large neurofibroma can cause large defect that needs various kinds of flap. The factors related to clinically suspected malignancy are painlessness, abrupt increase in size, firm fixation, and central ulceration, although the malignancy rate of neurofibroma is low. The complete resection was failed several times at local clinic, the patient was transferred to our hospital. We have successfully removed the retroauricular neurofibroma using transposition flap & free skin graft on its large defects.

Plexiform Neurilemmoma Unassociated with Neurofibromatosis - 2 Cases Report - (신경섬유종증의 동반이 없는 총상 신경초종 - 2 례 보고 -)

  • Lee, Kee-Haeng;Kim, Youn-Soo;Jeong, Chang-Hoon;Sung, Mi-Sook;Kim, Jean-A;Choi, Seung-Woog;Kim, Hyoung-Min
    • The Journal of the Korean bone and joint tumor society
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    • v.11 no.1
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    • pp.82-87
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    • 2005
  • Both neurilemmoma and neurofibroma are originated from Schwann cell. Plexiform tumor was mostly neurofibroma but Neurilemmoma which has plexiform is extremely rare. So it is important to differentiate plexiform neurilemmoma from plexiform neurofibroma, because plexiform neurilemmoma appears to have neither a significant association with neurofibromatosis nor a propensity for malignant transformation. We report two cases of plexiform neurilemmoma involving the left arm and right foot.

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A Case of Plexiform Neurofibroma Arising from Laryngeal Surface of Epiglottis (후두개 후두면에 발생한 망상형 신경섬유종 1예)

  • Kim, So Yeon;Kim, Tae Hwan;Lee, Sang Hyuk;Jin, Sung Min
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.26 no.2
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    • pp.137-140
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    • 2015
  • Neurofibroma is characterized as a benign, slow growing neoplasm, originating from Schwann cells or fibroblast in peripheral nerve sheaths. It may appear as a solitary tumor or have multiple localizations in von Recklinghausen disease. They are commonly found in the gastrointestinal tract and laryngeal neurofibromas are extremely rare, accounting for only 0.03 to 0.1% of benign tumors of the larynx. The aryepiglottic fold and arytenoid are the common site of occurrence for laryngeal neurofibroma, because the branch of the superior laryngeal nerve is involved. We present a case of solitary plexiform neurofibroma arising from the laryngeal surface of epiglottis in a 55-year old female who found the lesion incidentally. We removed the tumor completely by transoral laser surgery and no recurrence was found after 7 months. The case of solitary neurofibroma arising from laryngeal surface of epiglottis has not been reported in Korea. We report this case regarding the diagnosis and treatment with review of literatures.

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CLINICAL REPORT OF NEUROFIBROMATOSIS TYPE 1 PATIENT (제1형 신경섬유종증 환아의 임상적 치험례)

  • Lee, Dae-Woo;Yang, Yeon-Mi;Kim, Jae-Gon;Baik, Byeong-Ju;So, Yu-Ryeo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.38 no.2
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    • pp.187-193
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    • 2011
  • Neurofibromatosis is known as an autosomal dominant disorder caused by a mutation of a tumor suppressor gene on the long arm of chromosome 17 that affects the bone, nervous system, soft tissue, skin, and endocrine system. The most characteristic finding, which is helpful for clinical diagnosis as well, is the neurofibroma. Likewise brown macules called Cafe-au-lait spots with color of caffee latte, and Lisch nodules found around iris are useful to diagnose the disease. As known, the possibility of the neurofibromatosis occurred in oral cavity is relatively rare, and in most of cases it is related to soft tissue changes with single or multiple neurofibromatosis. The purpose of this report is to present characteristic dental findings which were found in a 4-year-old male and his father, both diagnosed as neurofibromatosis at Chonbuk National University Hospital before visiting our department, pediatric dentistry.

Malignant Schwannoma on the Right Chest Wall -1 Case Report- (흉벽에 발생한 악성 신경초종 -1례 보고-)

  • 황의두;황경환
    • Journal of Chest Surgery
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    • v.30 no.10
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    • pp.1051-1053
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    • 1997
  • Malignant schwannoma is rare tumor which is derived from schwas cells or nerve sheath cells, and it is frequently associated with Von Rechlinghausen's disease. We experienced one case of malignant schwannoma on the right chest wall without Von Rechlinghausen's disease. Patient was 64-year-old man who presented painless palpable mass on the right lower -chest wall for about 2 months. On chest computed tomography, the mass which was 6$\times$6 cm in size and had central necrosis, involved 11th rib with destruction, invaded the diaphragm and displaced the kidney anteriorlly. He underwent on-bloc resection of the tumor and discharged without any problem after 20 days.

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A SOLITARY NEUROFIBROMA OF THE FLOOR OF MOUTH (구강저에 발생한 단독형 신경섬유종)

  • Kim, Yong-Kack;Chung, Boong-Hee;Yu, Hyeon-Seok;Kwak, Jae-Keun;Kim, Kyu-Yeong
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.12 no.3
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    • pp.81-86
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    • 1990
  • Benign neural sheath neoplasms are not common in the maxillofacial region. These lesions can occur as solitary tumors, or they can affect many sites in the form of multiple neurofibromatosis. A solitary neurofibroma is seldom undergo sarcomatous transformation, since solitary neurofibroma is relatively radioresistant and its recurrence rate seems to be low, the treatment of choice is surgical excision. This case showed a solitary neurofibroma in the left side of the floor of mouth which occurred in a 33 - year -old female. The tumor was excised. And there is no evidence of disease. She is satisfied in function and esthetic aspect.

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Malignant Schwannoma in Neurofibroma with or without Neurofibromatosis - 3 Cases Report - (신경섬유종 (Neurofibroma) 환자에서 발생한 악성 Schwannoma -3예 보고-)

  • Kim, H.;Lee, D.Y.;Cho, B.K.;Hong, S.N.;Kim, S.K.;Cho, N.H.
    • Journal of Chest Surgery
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    • v.21 no.6
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    • pp.1103-1110
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    • 1988
  • We experienced 1 year old female patient with partial anomalous pulmonary venous return of the right lung into the inferior vena cava with atrial septal defect. Total anomalous venous drainage from the right lung is an uncommon form of congenital defect, and it may or may not be associated with an atrial septal defect. One patient having this venous anomaly is presented with a detailed description of the surgical reconstruction used. The postoperative result has been satisfactory.

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