A Case of the Solitary Neurofibroma at the Median Nerve -Ultrastructural Study-

정중신경에 발생한 신경섬유종 치험례 -초미형태학적 관찰-

With respect to the histogenesis of the neurofibroma, there are many controversies, since von Recklinghausen postulated that neurofibromas are mainly fibrous tumors arising from the connective tissue of the nerve sheaths. According to the recent studies through the electron microscope, the neoplastic perineurial cells are regarded as the main components of the tumor. So, the neurofibroma enucleated from the median nerve at the level of proximal arm without resulting neurologic sequale was examined through the light- and electron microscope. Ultrastructurally, this tumor is composed of the perineurial cells, fibroblasts, and collagen fibers. The predominant perineurial cells show distinct basal lamina, and contain abundant microfilaments.

저자들은 19세 남자 환자에서 정중신경에 발생한 신경섬유종을 신경학적 손상없이 제거하였다. 전자현미경을 통한 초미형태학적으로는 종양성 신경주막세포, 섬유아세포 및 교원섬유로 이 종양이 구성되었고 주된 세포는 신경주막세포로써 종양의 발생기전에 중요한 역할을 할 것으로 사료되어 문헌고찰과 함께 보고하는 바이다.