• Resources Recycling
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• v.30 no.2
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• pp.14-23
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• 2021

To investigate the potential for leaching of heavy metals by bacteria from ores stacked on actual mining sites, leaching tests of a complex metallic ore (Pb-Zn-As ore) were conducted over 60 days using acidophile bacteria Acidithiobacillus ferrooxidans and Acidithiobacillus thiooxidans under initial acidic conditions. Initially, a small amount of heavy metals was leached due to the initial acidic conditions. After 20 days, when A. thiooxidans in the reactor was adapted to the ore, the amount of leached heavy metals rapidly increased; the concentrations of leached arsenic, iron, and zinc reached a maximum of 2800, 3700, and 2500 mg/L, respectively. On the other hand, in the presence of A. ferrooxidans or in the control test without bacteria, heavy metals, except zinc, were barely detected in leaching. Through this study, it was confirmed that (i) bacteria could leach heavy metals at mining sites under acidic conditions and (ii) leaching of heavy metals from a high arsenic-containing ore by A. thiooxidans was more significant than that by A. ferrooxidans.

• Korean Journal of Breeding Science
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• v.49 no.4
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• pp.396-402
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• 2017

'Daname' is a foxtail millet(Setaria italica Beauv.) variety developed and registered by Department of Southern Area Crop Science, NICS, RDA in 2014. This variety which collected from IT252182 was developed through pure line selection. 'Daname' is a early-maturing variety having 100 days of growth period from seeding to harvesting in Milyang of Korea. The culm length is about 97 cm which is 20cm shorter culm length than standard variety 'Hwanggeumjo', and it showed tolerant to lodging in field. The panicle shape is a cylindrical and the length is about 19cm. According to the grain, seed color and dehusked grain colors are orange and yellow and endosperm characteristic is non-glutinous. The yield performance of this variety was about $3.81t\;ha^{-1}$ in local adaptability test from 2013 to 2014 and it showed similar with standard variety 'Hwanggeumjo'. As the addition amount of 'Daname' in rice increased from 0% to 30% and 100%, the antioxidant ability of 'Daname' added rice and hardness/stickiness balances were increased. But we could not find out the difference of hardness/stickiness balances between 0%and 10% addition. So, 10% addition amount was concluded to increase antioxidant ability regardless eating quality of cooked rice. (Variety registration No. 6243)

• Journal of Life Science
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• v.29 no.7
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• pp.824-835
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• 2019

In recent decades, oncolytic viruses (OVs) have extensively been investigated as a potential cancer drug. Oncolytic viruses have primarily the unique advantage in the fact that they can only infect and destroy cancer cells. Secondary, oncolytic viruses induce the activation of specific adaptive immunity which targets tumor-associated antigens that were hidden during the initial cancer progression. In 2015, one genetically modified oncolytic virus, talimogene laherparepvec (T-VEC), was approved by the American Food and Drug Administration (FDA) for the treatment of melanoma. Currently, various oncolytic viruses are being investigated in clinical trials as monotherapy or in combination with preexistent cancer therapies like immunotherapy, radiotherapy or chemotherapy. The efficacy of oncolytic virotherapy relies on the balance between the induced anti-tumor immunity and the anti-viral response. Despite the revolutionary outcome, the development of oncolytic viruses for the treatment of cancer faces a number of obstacles such as delivery method, neutralizing antibodies and induction of antiviral immunity due to the complexity, variability and reactivity of tumors. Intratumoral administration has been successful reducing considerably solid tumors with no notable side effects unfortunately some tumors are not accessible (brain) and require a systemic administration of the oncolytic viruses. In order to overcome these hurdles, various strategies to enhance the efficacy of oncolytic viruses have been developed which include the insertion of transgenes or combination with immune-modulatory substances.

• Journal of the Korean Recycled Construction Resources Institute
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• v.7 no.2
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• pp.109-115
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• 2019

In case of the cracks in concrete, the penetration of deterioration ions such as chloride ions in to cracks is accelerated. According to the penetration of chloride ions, structural and durability problems to RC(Reinforced Concrete) structures are caused. In this study, the accelerated chloride diffusion coefficient which is in steady state is evaluated for 2 year aged normal and high strength FA(Fly Ash) concrete, after a range of crack depths are induced up to 1.0 mm in 56 aged day. Considering crack effect by linear regression analysis, high strength concrete has slightly less increasing ratio of diffusion coefficient by crack than normal strength concrete, and diffusion coefficient increases non-linearly as crack width is increased. Also, In two types of concrete, crack effect decrease as the curing period increase. In the case of quantifying crack and curing effect by using exponential function form, the coefficients of determination are higher than those of linear regression analysis. Under steady state, it is thought that there is not a high correlation between the crack effect and the curing effect, and considering the two independent effects, it is believed that reasonable prediction equation for diffusion of concrete with crack can be proposed.

• Korean journal of applied entomology
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• v.58 no.3
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• pp.233-238
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• 2019

For greenhouse crops, thrips is one of the major insect pests, but its control is difficult owing to short generation time, rapid escaping behavior, and development of pesticide resistance. Stratiolaelaps scimitus (Womersley) is a soil-dwelling predatory mite attacking various soil invertebrate species, including thrips. Using the method by growers' self-production, we mass-reared S. scimitus colony and investigated thrips control in the greenhouse chrysanthemum. The initial density of thrips was six individuals/flower. The treatment with one S. scimitus box in the greenhouse was estimated to be $1,000individuals/m^2$. From August to September 2018, the greenhouse was released with a total of 10 boxes of S. scimitus. The density of thrips in the untreated and the treated cultivar was $53.7{\pm}7.0$ and $13.5{\pm}1.7$ on the late September, respectively, which indicated a reduction of 74.9% in the treated cultivar. Our results suggest that S. scimitus was highly effective for the control of thrips in the greenhouse chrysanthemum although temperature is very high during the summer season.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.2
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• pp.76-82
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• 2019

This study has done to search for a solution to remove risk limitedly caused by separating weapon system acquisition from operation and maintenance at the view point of Logistic Commander who's responsible for stable operation and maintenance after acquiring weapon system. At the System development stage, unverified overhaul development plan may cause additional manpower and costs after the development, and furthermore it is likely to have risk to lower reliability of the military. Thus, research and development agency should write overhaul development plan at the System development stage, and it should be verified through evaluation and verification test. Secondly, during research and development, institutional supplementation is needed to calculate human and material resources writing overhaul development plan. Thirdly, it should be able to analyze proper operation & maintenance plan and cost for overhaul plan at the pre-investigation stage. Fourthly, the base which can develop overhaul concept and overhaul factors should be included in the need and need determination document. Lastly, for the weapon system which has small amount of high power figure, project management should be performed to be able to specify at the each acquisition level of weapon system to realize Article 28, clause 3 and 4 of Defense business law.

• Journal of the Korea institute for structural maintenance and inspection
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• v.23 no.2
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• pp.75-83
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• 2019

In this study, to propose the deterioration curves of urethane, ceramic, polysiloxane and fluorocarbon coating for the steel bridge, an accelerated corrosion tests were carried out. The each coating system wes applied on the top of the specimens, and circular initial defects were introduced with different diameters with 0.5, 1.0, 3.0, 5.0 mm. An accelerated corrosion test condition was used to simulate severe corrosive environment depending on ISO 20340. The deterioration curve of each coating type was evaluated based on deteriorated area from the circular defects. In order to evaluate the coating service life of installed steel bridge using deterioration curve, the acceleration coefficient was calculated at correlation between ISO 20340 and corrosivity categories by ISO 9223 based on field corrosion rate. From test results, the propagation rate of coating deterioration area was different to diameter of circular defects. In case of urethane coating, the coating service lifes of 3% deterioration area was evaluated in 31.8, 15.8, 9.9 and 3.9 years with C2, C3, C4 and C5 category.

• The Journal of Internal Korean Medicine
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• v.40 no.4
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• pp.730-741
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• 2019

Objective: The aim of this study was to report the effectiveness of traditional Korean medicine treatment with rehabilitation exercise on a chronic intracerebral hemorrhage patient with a severe gait disturbance. Method: The patient was treated with Korean herbal medicine (Gami-sibjeondaebo-tang) along with acupuncture, moxibustion, and rehabilitation exercise. The treatment effect was evaluated through the Manual Muscle Test (MMT) and the Korean version of the Modified Barthel Index (K-MBI). The gait of the patient was evaluated by Functional Ambulatory Category (FAC) and the Timed Up and Go (TUG) test. The spatiotemporal parameters were evaluated by a walkway system (GAITRite(R) system) and gait symmetry was evaluated by Symmetry Criterion (SC). Results: After 111 days of traditional Korean medicine treatment, the spatiotemporal parameters and symmetry of the patient's gait improved. Conclusion: This study suggested that traditional Korean medicine treatment with rehabilitation exercise could be effective for gait disturbance in patients with chronic intracerebral hemorrhage.

• The Korea Journal of Herbology
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• v.36 no.5
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• pp.101-108
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• 2021

Objectives : A root of Dipsacus asperoides C. Y. Cheng et T. M. Ai (D. asperoides) has been traditionally used as a medicinal resource in several Asian countries, including Korean and traditional Chinese medicine that has been traditionally used for treating several medical conditions including pain, arthritis, and bone fractures in Korea. In the present study, we investigated potential subacute toxicities of D. asperoides extract. Methods : C57BL/6 mice (male, 7weeks) were randomly divided into 4 groups of 5 mice. Except for the control group, the mice were orally administrated D. asperoides extract at doses of 50, 150, or 450 mg/kg/day for 2 weeks. At the end of the treatment period, all mice were euthanized, and the following parameters were examined: mortality, body weight, clinical signs, gross findings, hematology, serum biochemistry, organ weight, and histopathology. Results : There were no abnormalities in mortality, clinical signs, body weight, gross findings, or organ weight after repeated administration of D. asperoides extract for 2 weeks, compared with the control group. In addition, there were no significant changes in hematological, serum biochemical, and histopathological parameters between the control group and D. asperoides extract administrated groups with doses of up to 450 mg/kg/day. Conclusion : In this study, D. asperoides extract showed no significant toxicities at a dose of up to 450 mg/kg/day in mice. Although we could not confirm the toxic dose of D. asperoides extract, it can be considered safe for further pharmacological use.

• Korean Journal of Food Science and Technology
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• v.53 no.1
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• pp.40-45
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• 2021

Prior studies of physiologically active substances in grapes have focused only on the fruit, pericarp, and branches, as well as the pulp and seeds. The present study assessed the changes in quercetin-3-O-glucuronide (Q3OG) and flavonol glycoside content using grape leaves from Vitis labruscana B. and V. coignetiae at different growth stages and provided basic data for quality control. Content analysis showed that both varieties differed in Q3OG and flavonol glycoside content by growth stage, and the components were found to be high in the order of fruit, maturation, and coloration. Also, Vitis labruscana B. has a better vascular relaxation effect than Vitis coignetiae. These results suggest that in the use of grape leaves as a functional raw material, Q3OG and flavonol glycosides can be used as indicator components. In addition, if raw materials for each growth stage are mixed in a particular ratio, it will be a way to manage the specific efficacy and content of indicator components.