• Title/Summary/Keyword: 수명 연장

Search Result 995, Processing Time 0.029 seconds

Studies on Constituents of Higher Fungi of Korea(LVI) -General Constituents and lmmunostimulation of Ganoderma lucidum- (한국산(韓國産) 고등(高等) 균류(菌類)의 성분(成分) 연구(硏究)(제(第)56보(報)) -영지(靈芝)의 성분(成分) 및 면역촉진작용(免疫促進作用)-)

  • Lee, Myung-Hee;Kim, Ha-Won;Shim, Mi-Ja;Toh, Sang-Hak;Choi, Eung-Chil;Kim, Byong-Kak
    • The Korean Journal of Mycology
    • /
    • v.14 no.2
    • /
    • pp.149-163
    • /
    • 1986
  • To determine contents of general constituents of Ganoderma lucidum in Korea, the dried carpophores were analyzed. The contents of water, ash, crude lipid, crude protein and crude cellulose were 14.6, 2.0, 3.3, 23.6, and 59.0%, respectively. Among reducing sugars, maltose was the most abundant. Seventeen free amino acids were detected, showing alanine the highest value. The pH of hot water extract was 4.1-4.2. The spores of Ganoderma lucidum was flat and ovoidal long. Their size was $6.3-7.1{\times}3.5-4.3{\times}2.0-2.5\;{\mu}m$ long. To examine effects of life span against sarcoma-180 cells, Fractions A, B and C, were obtained from the extract of Ganoderma lucidum. The survival rates of Fractions A, B and C were 131.7, 162.5, and 141.7 %, respectively. In addition, to examine effects of Fraction B on cell-mediated immunity, delayed type hypersensitivity (=DTH) test was conducted. It restored the suppressed DTH in the sarcoma-180 bearing group up to 66.7%.

  • PDF

Data Dissemination Protocol based on Home Agent and Access Node for Mobile Sink in Sensor Network (센서 네트워크에서 홈에이젼트와 액세스 노드에 기반한 모바일 싱크를 위한 데이터 전송 기법)

  • Lee, Joa-Hyoung;Jung, In-Bum
    • The KIPS Transactions:PartC
    • /
    • v.15C no.5
    • /
    • pp.383-390
    • /
    • 2008
  • The mobile sink is most suitable to guarantee the real time processing to events in ubiquitous environment. However it brings many challenges to wireless sensor networks. In particular, the question of how to transfer the collected data to the mobile sink is an important topic in the aspect of effective management of wireless sensor nodes. In this paper, a new data dissemination model is proposed. Since this method uses the home agent and the access node concepts, it provides reliable and efficient data delivery to mobile sink with minimum overhead. In this proposed method, the information of the mobile sink which is constantly moving is informed only to the home agent node and the access node, instead of all sensor nodes. Thus, the collected data from sensor nodes are transferred to the fixed home agent and it sends these data to the mobile sink. Since the confliction phenomenon between data packets in wireless networks could be reduced, the success ratio of data arriving in the mobile sink is highly enhanced. In our experiments, the proposed method reduces the number of broadcast packets so that it saves the amount of energy consumed for transmitting and receiving the data packets. This effect contributes to prolong the lifetime of the wireless sensor networks operated by batteries.

Immuno-potentiating and Antitumor Effects against Mouse Sarcoma 180 by Crude Polysaccharides Extracted from Fruiting Body of Russula rosacea (장미무당버섯(Russula rosacea)의 자실체에서 추출한 조다당류의 생쥐 Sarcoma 180에 대한 면역증강 및 항암 효과)

  • Choi, Yon-Il;Lee, Geon-Woo;Hur, Hyun;Lee, U-Youn;Lee, Tae-Soo
    • The Korean Journal of Mycology
    • /
    • v.36 no.1
    • /
    • pp.84-92
    • /
    • 2008
  • Russula rosacea, one of edible and medicinal mushroom belonging Agaricales of Basidiomycota, has been known to have good inhibitory effects on sarcoma 180 and Ehrlich carcinoma of mice. Neutral saline soluble (0.9% NaCl), hot water soluble and methanol soluble substances (hereinafter referred to Fr. NaCl, Fr. HW and Fr. MeOH, respectively) were extracted from fruiting body of the mushroom. In vitro cytotoxicity tests, crude polysaccharides were not cytotoxic against cancer cell lines such as Sarcoma 180, HepG2, HT-29 and NIH3T3 at the concentration of $10{\sim}2000\;{\mu}g/ml$. Intraperitoneal injection with crude polysaccharides exhibited life prolongation effect of $21.4{\sim}45%$ in mice previously inoculated with Sarcoma 180. Fr. HW improved the immuno-potentiation activity of B lymphocyte by increasing the alkaline phosphatase activity by 6.8 fold compared with control at the concentration of $500\;{\mu}g/ml$. In case of Fr. NaCl, the numbers of peritoneal exudate cells and circulating leukocytes were increased by 6 and 2.6 folds at the concentration of 50 mg/kg, respectively. Therefore, the antitumor effect against mice Sarcoma 180 by Russula rosacea could be due to immunomodulating activity.

Antitumor and Immuno-potentiating activity against Mouse Sarcoma 180 by Crude Polysaccharides from Fruiting Body of Lentinus giganteus (대향고(Lentinus giganteus)의 자실체에서 추출한 조다당류가 생쥐의 Sarcoma 180에 미치는 항암 및 면역 증강효과)

  • Lee, Geon-Woo;Kim, Hye-Young;Hur, Hyun;Lee, Tae-Soo;Lee, U-Youn
    • The Korean Journal of Mycology
    • /
    • v.36 no.1
    • /
    • pp.75-83
    • /
    • 2008
  • Lentinus giganteus, one of edible and medicinal mushroom belongs to Pleurotaceae of Agaricales, has been known to contain some inhibitive substances on Sarcoma 180 and curative effect on high blood pressure. Neutral saline soluble (0.9% NaCl), hot water soluble and methanol soluble substances (hereinafter referred to Fr. NaCl, Fr. HW and Fr. MeOH, respectively) were extracted from fruiting body of the mushroom. In vitro cytotoxicity tests, crude polysaccharides were not cytotoxic against cancer cell lines such as Sarcoma 180 and HepG2 at the concentration of $10{\sim}2,000\;{\mu}g/ml$, but crude polysaccharides from Fr. NaCl was toxic to NIH3T3 at the concentration of $10{\sim}2,000\;{\mu}g/ml$. Intraperitoneal injection with crude polysaccharides showed life prolongation effect of $14.3{\sim}67.5%$ in mice previously inoculated with Sarcoma 180, respectively. Fr. NaCl exhibited the immuno-potentiating activity of B lymphocyte by increasing the alkaline phosphatase activity by $1.53{\sim}1.68$ folds compared with control at the concentration of $50{\sim}200\;{\mu}g/ml$, respectively. The numbers of peritoneal exudate cells and circulating leukocytes were increased by 7.7 and 1.6 folds by injecting Fr. NaCl and Fr. MeOH into the mice at the concentration of 50 mg/ml body weight, respectively.

The Knowledge, Attitude, and Practices Related to Noncommunicable Diseases Among Korean Adults Residing in Urban and Rural Areas -Focusing on Hypertension, Diabetes, and Cancer- (도시 및 시골에 거주하는 성인들의 성인병에 대한 지식, 태도 및 실천 - 고혈압, 당뇨병 및 암을 중심으로 -)

  • Kim, Byung-Sung;Kim, Kong-Hyun;Lee, Chae-Un;Shin, Hae-Rim;Park, Hyung-Jong
    • Korean Journal of Health Education and Promotion
    • /
    • v.9 no.1
    • /
    • pp.14-29
    • /
    • 1992
  • 의학이 발달하고 수명이 연장되고, 그리고 식사가 보다 서양화되는 등 생활양식이 변화됨에 따라 성인병이 1970년대부터 한국에 보다 늘어나게 되었다. 본 연구는 면접 및 설문지법을 이용하여 성인병, 특히 고혈압, 당뇨병 및 암에 관하여 도시 및 시골 거주자들의 지식, 태도 및 실천을 비교 연구하였다. 연구기간은 1990년 1월 부터 12월까지 1년동안이었고 대상은 전체 716명으로 그중 360명은 부산시 거주자였고 356명은 부산 근교의 시골거주자였다. 고혈압, 당뇨병 및 암에 대해 알고 있다고 응답한 대상자는 각각 92.6%, 92.0% 및 74.7%였다. 고혈압, 당뇨병 및 암의 지식도에 있어서 도시 거주자들이 시골 거주자보다 유의하게 더 많이 알고 있었다(각각 p<0.001). 그러나 성인병에 관한 태도와 지식에 있어서는 도시 거주자와 시골 거주자 사이에 유의한 차이가 없었다(p<0.05). 고혈압의 지식도는 거주지(r=0.2159, p<0.01) 및 수입 (r=0.1882, p<0.01)과 유의한 상관관계가 있었고, 당뇨병에 관한 지식도는 거주지(r=0.3952, p<0.001), 수입(r=0.3663, p<0.001) 및 직업(r=0.2576, p<0.001), 수입(r=0.4138, p<0.001), 직업(r=0.3044, p<0.001) 및 성별(r=-0.1887, p<0.01)과 유의한 상관관계가 있었다. 성인병에 관한 태도는 성별(r=0.4748, p<0.001), 경제상태(r=0.2209, p<0.01) 및 고혈압 지식도(r=0.1844, p<0.01)와 유의한 상관관계를 나타내었다. 성인병에 관한 실천은 본 연구에서 어떤 변수와도 상관관계가 없는 것으로 나타났다. 성인병이 이전보다 더 많아짐에 따라 연령이 증가하는 나라와 개발국가에서 성인병이 주요한 대상질환이 될 것이고, 질병예방과 건강증진의 차원에서 성인병을 예방하기 위해 보건교육에 보다 중점을 두어야 할 것이다.

  • PDF

Antioxidative and Antitumor Activities of Crude Polysaccharide Fraction from P leurotus eryngii (큰느타리버섯(Pieurotus eryngii) 조다당체 분획의 항산화 및 항종양활성)

  • Kim, Jae-Yong;Kang, Hye-In;Park, Kyung-Uk;Moon, Kwang-Deog;Lee, Sang-Dae;Cho, Sook-Hyun;Wee, Jae-Joon;Kyung, Jong-Soo;Song, Yong-Beom;Seo, Kwon-Il
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.33 no.10
    • /
    • pp.1589-1593
    • /
    • 2004
  • The aims of this study were to investigate the antioxidative and antitumor effects of crude polysaccharide fraction from Pleurtus eryngii (CPPE). CPPE inhibited autoxidation of linoleic acid at 1,000 $\mu$g/mL concentration, and the inhibitory rates of lipid peroxidation in rat liver microsome were 5.28, 9.40, and 32.5% at 10, 100, and 1,000 $\mu$g/mL concentrations, respectively. After treatment with CPPE for 72 hours, the inhibitory rates against MCF-7, A549 and AGS cell lines showed 42.3, 33.4 and 26.7% at concentration of 1,000 $\mu$g/mL, respectively. Results of CPPE treatment at 100 and 300 mg/kg/day for 7 days in sarcoma-180 bearing-mice showed survival rates of 70 and 90%, respectively. Body weights of mice treated with CPPE were significantly decreased when compared with the control.

An Experimental Study on the Flexural Behavior of One-Way Concrete Slabs Using the Restorative Mortar and Crimped Wire Mesh (크림프 철망 및 단면복구 보수 모르타르를 사용한 일방향 슬래브의 휨 거동에 관한 실험적 연구)

  • Lee, Mun-Hwan;Song, Tae-Hyeob
    • Journal of the Korea Concrete Institute
    • /
    • v.19 no.5
    • /
    • pp.569-575
    • /
    • 2007
  • The repair of concrete surfaces does not normally take into account structural tolerance for longer service lift and better capabilities of concrete structures. In particular, the repair of surface spelling completes as mortar is applied, which does not display additional structural performances. The use of crimped wire mesh for better construction and fracture resistance, however, expects to have some reinforcement effects. Particularly, it is also expected that the repair of bottom part in structures built between bridges like irrigation structures results in the increase of flexural resistance. Therefore, this study is intended to perform the repair using crimp wire mesh and examine strength depending on the repair section and depth. For this, a slab with 150 mm in depth, 3,000 mm in length and 600 mm in width and total 8 objects to experiment such as upper part, upper whole, bottom part, bottom whole and crimp wire mesh reinforced are manufactured to perform flexural performance. The results of the analysis show that yield strength and failure load increase as the depth of repair materials in the experiment reinforced with crimp wire mesh get bigger. In the same condition, repair of bottom part is able to increase internal force of bending force. Besides, the results show that partial repair of structures under bending force cannot produce flexural performance. Consequently, the repair method with crimp wire mesh results in the increase of flexural resistance.

Experimental Investigation on Cracks and Defects of a Valve Sealing Components for a LPG Cylinder (LPG 용기용 밸브의 밀봉부품 크랙 및 결함에 관한 실험적 고찰)

  • Kim, Chung-Kyun;Lee, Byung-Kwan;Kim, Tae-Hwan
    • Journal of the Korean Institute of Gas
    • /
    • v.11 no.1 s.34
    • /
    • pp.23-28
    • /
    • 2007
  • This paper presents an experimental investigation on the sealing defects and cracks of O-rings and a valve packing of a gas valve for a LPG cylinder. O-ring in which stops a gas leakage of a liquefied petroleum gas is very important for a LPG valve safety. Valve packing is to open and close a gas flow port for supplying and charging a LPG fuel. The sealing performance of two sealing units ism related to the leak safety and long lift of a gas valve. The investigated results show that most of O-rings was failed due to a circumferential crack in which is caused by partial press bonding failure near the partition zone and an excess compression rate. Some of the O-ring failure was originated by an extrusion of an excessive leak pressure of a LP gas. Thus, this paper strongly recommends a tight quality control and a safety guarantee system of O-rings and valve packing to guarantee a leak safety and to extend a service lift of a gas valve. At the end, a warranty policy of the sealing units should be adopted for increasing a product quality and safety of a gas valve.

  • PDF

Experimental Study for The Development of a Blower to Extend The Life of The Impeller and Reduce The Power Cost by Changing the Air Flow (공기흐름 변경으로 임펠러의 수명연장과 전력비 절감을 위한 송풍기 개발을 위한 실험적 연구)

  • Kim, Il-Gyoum;Park, Woo-Cheul;Sohn, Sang-Suk;Kim, Young-Nam
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.21 no.11
    • /
    • pp.219-225
    • /
    • 2020
  • In this study, the prototype of a blower was designed and made to develop a long-life blower with a volume flow rate of 10,000 ㎥/min with a required total pressure efficiency of 83% or more. Five experimental impellers with various lengths of dust deflectors were manufactured and used for the erosion experiments. The erosion test was conducted by operating for 160 hours in a self-produced closed loop-type erosion test apparatus. A prototype of a model blower was designed, fabricated, and tested. The results revealed a total pressure, air volume flow rate, and efficiency of 690.6 mmAq, 16,243.6 ㎥/min, and 83.6%, respectively, as the result of conversion to a blower based on the measured value of the blower model. The prototype was designed and fabricated as the experimental erosion equipment of the blower. A blower with a dust deflector was developed by performing the erosion experiments under harsh conditions. The blower showed an improved effect of more than 190% based on the wear thickness of the impeller compared to a conventional blower without a dust deflector.

Quality Changes of Retorted Samgyetang During Storage Depending on the Degassing Methods (탈기 포장 방법에 따른 레토르트 삼계탕의 저장 중 품질 변화)

  • Jang, Min Jun;Lee, Jin Ho;Lee, Keun Taik
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
    • /
    • v.19 no.2
    • /
    • pp.67-73
    • /
    • 2013
  • This study investigated the quality changes of Samgyetang during storage, resulting from various degassing methods used at the packaging stage. Three different samples were prepared, one without any treatment (CON), a second with reduced head space volume by squeezing the pouch (RHS), and a third by flushing with nitrogen gas (NGF). These were retorted at $120^{\circ}C$ for 65 min under the F-value of approx. 8.0, and stored at $25^{\circ}C$ for 9 months. The oxygen ratio in the head space and the dissolved oxygen content of NGF samples tended to be lower than those of other samples over the storage period. Compared to the CON, the acid values of NGF and RHS samples were lower than the CON from month 3 and 6 (p<0.05). During storage, volatile basic nitrogen values of NGF and RHS samples increased slowly compared to the CON. To delay quality deterioration and extend the shelf-life of Samgyetang products, the reduction of oxygen content in the head space of the retort pouch (preferably by flushing with nitrogen gas) is recommended, even though no significant differences in sensory evaluation were observed among the samples during 9 months of storage (p>0.05).

  • PDF