• Journal of Yeungnam Medical Science
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• v.24 no.2
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• pp.311-314
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• 2007

The extraaxial presentation of a medulloblastoma is rare. This article describes the case of a 12-year-old boy who presented with severe headache, nausea, and vomiting. The tumor developed in the left tentorium; it was misdiagnosed as a meningioma based on the radiology examination. We review the literature and discuss the atypical presentation of medulloblastoma.

• THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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• v.9 no.1
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• pp.47-52
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• 2003

Acupuncture is a complementary medical treatment whose use in cancer patients has been recommended by the American Cancer Society (ACS) for the treatment of cancer and treatment-related symptoms. Pain, nausea, breathlessness, vasomotor symptoms and limb edema have all been found to respond to this treatment modality. This has become quite familiar to many Koreans not only for pain, but also for many other health problems, both in acute and chronic conditions. Actually, acupuncture is a therapeutic technique that is part of a larger system of traditional oriental medicine. There are several styles of acupuncture. We treated one 72-year-old female patient with Dongshiqixue Acupuncture Technique who had refused surgical operation for brain meningioma showing right hemiparesis, dysarthria, headache and dizziness. During the acupuncture treatment, there were no other adverse effects. After six day's treatment, she could ambulate and make usual life all by herself. On her brain magnetic resonence image follow-up, there was no interval change in meningioma. After discharged from our hospital, she has kept up her independent daily life as before. So it is suggested that some acupuncture treatment should be effect on brain meningioma clinically.

• Journal of Veterinary Clinics
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• v.26 no.3
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• pp.290-297
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• 2009

A 5-year-old, castrated male Yorkshire Terrier with strabismus and exophthalmos of the right eye was referred to the Veterinary Medical Teaching Hospital, Chungnam National University. Radiography, ultrasonography(US), computed tomography(CT) and magnetic resonance imaging(MRI), demonstrated a well-circumscribed, locally calcified mass of the retrobulbar region with contiguous bone structures invaded. Surgical removal of the adnexa, globe, optic nerve and the incorporated orbital neoplasm was performed. Primary orbital meningioma was confirmed by histopathologic examination.

• The Korean Journal of Cytopathology
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• v.7 no.2
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• pp.169-176
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• 1996

This study was peformed in order to evaluate the usefulness of the crush cytologic features and differential diagnosis between meningiomas and schwannomas in the central nervous system. Deeply seated and unusually located meningiomas and schwannomas with equivocal or erroneous frozen section diagnosis can be correctly diagnosed cytologically in crush preparations. Twenty-four meningiomas and nine schwannomas were studied by frozen section and crush preparation technique. These tumors displayed distinctive cytologic features. in meningiomas, the tumor tissue fragments were easy to crush, and the tumor cells were arranged in small clusters, flat sheets, papilla-like, whorling pattern or singly. Individual tumor cells displayed round or oval nuclei with finely granular chromatin pattern and inconspicuous small nucleoli. Occasionally psammoma bodies, nuclear pseudoinclusion or nuclear grooves were found. In schwannomas, tissue fragments were hard in consistency and difficult to crush. The crushed tissue presented as thick, irregular fragments with shard borders. The cells showed ill-defined cytoplasm and round, oval, cigar-shaped or curved nuclei. It is important to emphasize that the smear pattern under low-power view and cytologic features are helpful in discriminating between these two tumors.

• Journal of Korean Neurosurgical Society
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• v.29 no.9
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• pp.1222-1227
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• 2000

Objective : Vascular endothelial growth factor(VEGF), an endothelial cell specific cytokine, is a potent angiogenic growth factor implicated in the tumor angiogenesis and increases vascular permeability dramatically. Peritumoral brain edema(PTBE) occurs in 40-60% of meningiomas. Many causative factors have been investigated, but the mechanism of PTBE associate with meningioma is unclear. VEGF has been implicated as one of the causative factors of PTBE. This study was designed to determine whether the extent of VEGF expression is correlated with degree of PTBE in meningiomas. Methods : Meningioma tissue samples from 40 patients(7 men and 33 women, mean age $53{\pm}13years$) who underwent surgery were examined retrospectively for the expression of VEGF immunohistochemically. The extent of PTBE was estimated by using preoperative CT or MRI as an edema index(EI). In addition to VEGF, several causative factors including tumor size, location, histologic type, microvasculature(CD31) were compared with EI. Results : Twenty-six meningiomas demonstrated PTBE, and the other 14 did not. Of the 40 patients of meningiomas, 28 were positive(17 were 1+ and 11 were 2+) for VEGF. The EI increased significantly just as VEGF was strongly expressed(p=0.006). Microvascular proliferation was also closely correlated with the extent of peritumoral brain edema(p<0.05). Conclusion : These data suggest that VEGF expression and microvascular proliferation are closely correlated with PTBE in meningioma.

• Journal of Veterinary Clinics
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• v.27 no.1
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• pp.97-101
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• 2010

A 13-year-old neutered female Maltese was referred to Veterinary Medical Teaching Hospital of Seoul National University with 8-month-history of gradually enlarging retrobulbar mass in the right eye. On the ophthalmic examinations, exophthalmos, exposure keratitis, and cataract were observed, and menace response was absent in the eye. The fellow eye was normal except for nuclear sclerosis. On the ocular ultrasonographic evaluation, a mass was identified in retrobulbar and periocular region in the right eye. Exenteration was performed in order to remove the mass. Histopathologic evaluation revealed that most part of the mass was composed of epithelial-like neoplastic cells. Invasion into adipose cells and osseous metaplasia around the mass were also confirmed. Based on the radiologic and histopathologic examination, the mass in the right eye was diagnosed as primary retrobulbar meningioma. Eleven months after the surgery, recurrence was not observed.

• Journal of Korean Neurosurgical Society
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• v.29 no.11
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• pp.1523-1526
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• 2000

It has been known that hemangioblastoma of spinal cord occurs about 4% of all the spinal tumors. The authors present a rare case of intradural extramedullary(IDEM) hemangioblastoma of distal spinal cord in 41-year-old male patient. This IDEM mass at the level of conus medullaris showed iso-signal intensities on T1-weighted image(T1-WI) and high-signal intensities on T2-WI, and was enhanced homogeneously on MRI. At surgery, T12- L1 total laminectomy and enbloc mass removal were performed. This IDEM hemangioblastoma was confirmed by histopathologic findings. For less postoperative complication in IDEM tumors, we suggest that precise preoperative evaluation and complete excision via proper surgical approach to distal conus should be reemphasized.

• International Journal of Highway Engineering
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• v.17 no.1
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• pp.105-118
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• 2015

PURPOSES : This study aims to evaluate the road safety of the super-elevation transition section of a left turn curve and suggest the minimum longitudinal grade of a super-elevation transition section to be used before and after a left curved section. METHODS : We evaluated the road condition by means of the safety-criterion-evaluation method involving side friction factors, and then solve the problem by introducing the minimum longitudinal grade criterion based on conditions described in the hydraulics literature. RESULTS : It was calculated that when a road satisfies hydroplaning conditions, the difference between side friction assumed and side friction demanded is less than -0.04. In this case, the safety criterion for the condition is unsatisfied. Conversely, when a road is in a normal state under either wet or dry conditions, it was calculated that the difference between side friction assumed and side friction demanded is more than 0.01. Thus, the safety criterion for this condition is found to be satisfied. After adjusting the minimum longitudinal grade applied to a super-elevation transition section, the hydroplaning condition can be eliminated and the safety criterion can be met for all sections. CONCLUSIONS : It is suggested that a minimum longitudinal grade should be provided on super-elevation transition sections in order to prevent hydroplaning.

• Journal of Korean Neurosurgical Society
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• v.30 no.11
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• pp.1263-1270
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• 2001

Objective : To analyze the radiosurgical results of intracranial meningiomas after Gamma Knife radiosurgery (GKS) and to assess the possible factors related to the outcome and complications in treating meningiomas. Patients and Methods : We retrospectively reviewed the clinical and radiological data in 179 patients(194 lesions) treated with GKS for intracranial meningiomas between May 1992 and October 2000. Radiosurgical responses were categorized as shrinkage, stasis and enlargement, and we defined the shrunken and static group as a radio-logical control. A Cox proportional hazards model was used to evaluate the correlation between the radiosurgical outcomes and various factors such as location and size of tumor, age and gender of patients, relation to venous sinus, pre-GKS degree of edema, treatment modality, radiosurgical parameters, and pathologic findings. Results : Patients were grouped into skull base meningiomas(57.7%), non-skull base tumor including convexity, parasagittal, and falx meningiomas(37.1%), and others(5.2%) according to the location of tumors. The mean maximum dose and the margin dose of tumor was 30.0Gy(19-45Gy) and 15.1Gy(9.5-24.5Gy), respectively. The mean volume of the tumors was 9.4cc(0.003-45.0cc). The radiologic control rate was 97.1%. The radiation induced imaging change with or without neurologic deficit was the most common complication(23.6%). There were seen mostly in convexity, parasagittal, and falx meningiomas which were deeply embedded in cortex. Conclusion : GKS for intracranial meningioma seems to be safe and effective treatments. However, GKS should be considered very cautiously in non-skull base tumor such as convexity, parasagittal, or falx meningiomas with regards to patient's age and general condition, size and location of tumor, pattern of embedding into cortex, presenting symptoms and patient's preference.

• Journal of the Korean Society of Radiology
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• v.2 no.1
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• pp.17-21
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• 2008

Because of the reason that the meningioma is enhanced lately, we started the study to maximally enhance the meningioma. we were to know the relation between meningioma and vessels in the skull and compared 3D CT angiography with the conventional angiography. we got the data from 6 patients performed by both 3D CT angiography and there were 5 cases in sphenoidal ridge and 1 case parasagittal sinus. Injecting the contrast media at 3 ml/sec, 120 ml and then the CT number reached 100, we started the study using the medical system Program(smart prep). The scan parameters were HS-Mode(1.25 mm / 7.5 mm) right after being injected all and reconstructed with 0.5 mm interval. We compared the study with the conventional angiography after reconstructing the images required by using 3D-Med software Program(Rapidia). Seeing the consequences, the maximum enhancing time in the menigioma is about 120~180 seconds after injecting the contrast media and we distinguished the relation between vessels and tumors at the time and 1 case showed us the aneurysm with a tumor clearly at the time too. It was very helpful to the operation that the 3D images required by injecting the contrast media to the patients with meningioma distingushed between tumors and vessels dimensionally.