• Clinical and Experimental Pediatrics
• /
• v.45 no.10
• /
• pp.1199-1203
• /
• 2002

Purpose : The study aimed to evaluate the efficacy of auditory brainstem response(ABR) as a screening tool in children with speech and language disorders. Methods : Between January 1, 1999 and December 31, 2001, 139 patients with chief complaints of speech and language delay were recruited from the pediatric neurology clinic, Kyungpook National University Hospital, Daegu, Korea. They had ABR on entry and the clinical data were then analyzed. Results : Fifteen out of 139 cases(10.8%) showed abnormal findings; seven had pervasive developmental disorders, four had developmental language disorders, and four were noted to have other conditions. Among them, seven cases were noted to have conductive hearing loss and eight had sensoryneuronal hearing loss. We also evaluated the normal values in children at the ages of 18 months to seven years. The mean latency of wave I and V were $1.40{\pm}0.13$ and $5.57{\pm}0.26$ respectively. Interpeak latency of I-V was $4.18{\pm}0.24$. Conclusion : Based on these findings, ABR has proved to be a highly sensitive and specific index of hearing impairment. It should be used as a screening tool in children with speech and language disorders.

• The Journal of the Korea Contents Association
• /
• v.20 no.12
• /
• pp.383-392
• /
• 2020

This study was conducted to understand the current status associated with challenging behaviors of adults with developmental disabilities and review the perception of workers at lifelong education centers for the developmentally disabled. To that end, a survey and a focus group interview were conducted. The findings were as follows. First, 85.4% of people working at lifelong education centers for the developmentally disabled had experienced injury in the past year due to challenging behaviors, and those who experience injuries responded that they suffered burnout, psychological trauma, and considered changing jobs. Second, in terms of preemptive response by the organization to address challenging behaviors, 'securing individual space' and 'preemptive identification of causes of challenging behaviors' ranked the highest, with 87.5% of the respondents giving this answer, respectively. For follow-up measures, 81.3% of organizations answered that they hold meetings on individual cases and provide supervision. Third, in terms of suggestions for ways to address challenging behaviors, establishment of an organization-wide system and cooperation with related organizations were cited as needed.

• Korean journal of applied entomology
• /
• v.48 no.2
• /
• pp.123-158
• /
• 2009

An attempt was made to stimulate future research by providing exemplary information, which would integrate published knowledge to solve specific pest problem caused by resistance. This review was directed to find a way for delaying resistance development with consideration of chemical(s) nature, of mixture, rotation, or mosaics, and of insecticide(s) compatible with the biological agents in integrated pest management (IPM). The application frequency, related to the resistance development, was influenced by insecticide activity from potentiation, residual period, and the vulnerability to resistance development of chemical, with secondary pest. Chemical affected feeding, locomotion, flight, mating, and predator avoidance. Insecticides with negative cross-resistance by the difference of target sites and mode of action would be adapted to mixture, rotation and mosaic. Mixtures for delaying resistance depend on each component killing very high percentage of the insects, considering allele dominance, cross-resistance, and immigration and fitness disadvantage. Potential disadvantages associated with mixtures include disruption of biological control, resistance in secondary pests, selecting very resistant population, and extending cross-resistance range. The rotation would use insecticides in high and low doses, or with different metabolic mechanisms. Mosaic apply insecticides to the different sectors of a grid for highly mobile insects, spray unrelated insecticides to sedentary aphids in different areas, or mix plots of insecticide-treated and untreated rows. On the evolution of pest resistance, selectivity and resistance of parasitoids and predator decreased the number of generations in which pesticide treatment is required and they could be complementary to refuges from pesticides To enhance the viability of parasitoids, the terms on the insecticides selectivity and factors affecting to the selectivity in field were examined. For establishment of resistant parasitoid, migration, survivorship, refuge, alternative pesticides were considered. To use parasitoids under the pressure of pesticides, resistant or tolerant parasitoids were tested, collected, and/or selected. A parasitoid parasitized more successfully in the susceptible host than the resistant. Factors affecting to selective toxicity of predator are mixing mineral oil, application method, insecticide contaminated prey, trait of individual insecticide, sub-lethal doses, and the developmental stage of predators. To improve the predator/prey ratio in field, application time, method, and formulation of pesticide, reducing dose rate, using mulches and weeds, multicropping and managing of surroundings are suggested. Plant resistance, predator activity, selective insect growth regulator, and alternative prey positively contributed to the increase of the ratio. Using selective insecticides or insecticide resistant predator controlled its phytophagous prey mites, kept them below an economic level, increased yield, and reduced the spray number and fruits damaged.

• Journal of Music and Human Behavior
• /
• v.4 no.2
• /
• pp.84-105
• /
• 2007

Cerebral palsy is a collection of motor disorders resulting from damage to the central nervous system that arise in multiple handicaps including cognitive disorders, speech disorders, epilepsy, perception disorders, and emotion disorders. Today spastic cerebral palsy has become more prevalent because intensive care for newborns has resulted in higher survival rates for very small premature babies. Since the children grow the fastest in order for a development during one year after birth, the therapeutic intervention is provided as early as possible to the children with cerebral palsy. After seven year old, there is no effect of intervention. So, the necessity of early intervention to spastic cerebral palsied infants is increasing. The purpose of this study is to develop the music therapy activity program using the techniques of neurological music therapy(NMT), the therapeutic application of music to dysfunctions due to neurologic disease of the human nervous system, for rudimentary movement phase of spastic cerebral palsied infant. This music therapy activity program was developed on the basis of the major developmental tasks of the rudimentary movement phase, the period that children can acquire the most basic movement function at the 0 to 2. Then the developmental characteristics of spastic cerebral palsy were applied to this music therapy activity program. This music therapy activity program was classified to three domains, those are stability, locomotion, and manipulation. This study has been consisted of three steps, those are the development of the activities, the evaluation of the activities by th panels, and the adjustment and complement of the activities. Reviewing literatures and interviews were done for the development of the activities, and the evaluation the activities was done by seven music therapists. In the evaluation steps, the questionnaire was used for estimating the content validity and application efficiency. The adjustment and complement of the activities were evaluated by the panels who were participating in the music therapy for cerebral palsied children in the clinical setting, and the results of the adjustment and complement were confirmed by the panels. The evaluation was presented in a mean value with the comment of the panels. In conclusion, the music therapy activity program for the spastic cerebral palsied infants using the techniques of NMT was developed on the basis of the major developmental tasks of the rudimentary movement phase. The program is comprised of 38 activities, those are 14 activities for developing the stability, 10 activities for developing the locomotion, and 14 activities for developing the manipulation. The programed activities would bring out the answers in the affirmative for the conformance with infants' development phase, the harmony between the objective and the activity, the conformance with the cerebral palsied infants, the properness of the music and the instruments, and the utility in the clinic field. This results mean that this developed music activity program is appropriate to help spastic cerebral palsied infants progress their movement development by stages.

• Proceedings of the Korean Society for Rock Mechanics Conference
• /
• 2001.10a
• /
• pp.69-82
• /
• 2001

본 연구는 절리가 발달한 고속도로 절취 사면들의 안정성을 검토하기 위하여 수행되었다. 물성시험을 바탕으로 한 지질 강도지수(GSI)를 이용하여 절리가 발달한 암반에 대한 최적의 물성을 구하는 과정을 제시하였다. 안정성 검토를 위해 FLAC에 의한 수치해석을 실시하였으며 이 때 사용한 모델은 절리 발달 상태가 균일하게 분포하였으므로 Ubiquitous Joint Model을 선정하였다. 해석은 건기와 우기의 경우로 나누어 실시하였는데 조건에 따라 절리면의 강도를 달리 적용하였다. 본 논문은 굴착 사면에서 쉽게 접할 수 있는 절리암반 환경에서 최적의 물성을 결정하고 이를 이용하여 안정성을 분석할 패 하나의 참고자료로 활용할 수 있을 것이다.

• Journal of the Korean Home Economics Association
• /
• v.36 no.11
• /
• pp.193-207
• /
• 1998

이 연구의 목적은 아동의 연령과 성에 따른 아동의 역량지각 발달의 경향을 조사하고, 연령, 성을 포함한 가정환경과 또래 환경의 변수들의 역량지각에 미치는 영향을 구조평형 모델을 통해 알아 보았다. 또한, 이러한 역량지각의 발달 성향을 서구 문화권과 비교하여, 역량지각발달의 문화적 보편성이나 차이점을 알아 보고자 하였다. 유아, 또는 초등학교 저학년 아동은 면접으로, 그리고 3학년이상은 설문지를 사용하였다. 조사 대상은 유아, 초등학교 1, 3, 5학년, 중학교 1학년 아동 750명과 그들의 어머니이다. 인지, 사회, 신체 영역에서 모두 역량지각은 연령이 증가할수록 낮아졌다. 인지, 신체 영역의 역량지각에선 연령과 성의 상호작용효과가 나타났다. 그러나, 서구 문화권의 연구에서는 이러한 상호작용이 발견되지 않는다. 역량지각의 공변량구조모형에서는 또래환경 변수가 모두 포함시키기에 부적합한 변수로 나타났고, 연령, 성과 가족의 수입, 아버지의 교육수준, 가정의 물리적 환경, 부모의 정서적 지지가 아동의 역량지각에 의미 있게 영향을 미치는 것으로 나타났다.

• Journal of the korean Society of Automotive Engineers
• /
• v.5 no.4
• /
• pp.23-33
• /
• 1983

급속한 산업발달과 도시인구의 집중화로 자동차의 이용도가 높아져 이를 육지의 교통 및 수송 수단으로 가장 널리 사용하고 있는 현실이다. 자동차는 1886년 독일의 다이믈러가 사륜가솔린 자동차를 발명한 이래 1913년 미국의 헨리,포오드가 대량생산으로 만들어 개인화가 시작되어 오늘에 이르기까지 끊임없이 발전을 거듭해 왔다. 더욱이 자동차공업은 기계, 금속, 전자, 화학 공업 등이 총망라된 종합공업으로 이들 공업의 발달에 병행하여 모든 산업분야의 발전에 크게 기여해 왔다. 특히 전자공업의 발달에 따라 자동차 생산제공정의 자동조작과 자동차 자체의 작 동에도 많은 컴퓨터 시스템의 이용이 두드러지고 있다. 최근에 들어 에너지위기와 공해문제의 대두로 연료절약(fuel saving) 및 저공해(low pollution)의 자동차 생산에 많은 연구개발이 집중 되며 또한 쾌적성(comfortability), 조향안정성(maneuverability), 내구성(durability), 신뢰 성(reliability)등 까지 중요한 연구개발테마로 하여 많은 발전을 계속하고 있다. 본 고에서는 현재 자동차공업의 선진국인 미국, 일본을 중심으로 유럽 여러나라들의 자동차공업의 현황과 자동 차공업이 직면한 사회적 문제 및 장래의 전망에 대하여 통계적 수치를 중심으로 고찰하고자 한 다.

• Horticultural Science & Technology
• /
• v.33 no.3
• /
• pp.420-428
• /
• 2015

The majority of cultivated varieties of grape have perfect flowers that are clustered in an individual inflorescence. Grape flower has a single pistil, five stamens, a protective flower cap (calyptra), and a calyx. After fertilization, an individual flower develops into a single berry. Although there are a number of reported studies focusing on berry formation, berry enlargement, and sugar accumulation in grape, the morphological studies of flower, including gametophyte morphogenesis and structural change in floral organs, have not yet been studied in detail. In this study, we investigated the flower structure and development characteristics of grape using microscopy and defined the floral development stages 9 to 13 based on microspore or male gametophyte development stage from tetrad to mature pollen. We used seeded diploid table grapes 'Campbell Early' (Vitis labruscana) and 'Tamnara' (V. spp.) as plant materials. At floral development stage 9, pollen mother cells develop to tetrads. During floral development stages 10 to 11, unicellular microspore develop to mid bicellular pollen. At the end of floral stage 12, male gametophyte develops to mature tricelluar pollen. In floral stage 13, the flower cap falls off and flower bud opens. During floral development stages 9 to 12, there were no major changes in calyx length, whereas the length of the flower cap continuously increased. The flower cap-to-calyx length ratio was 2.0, 3.0, 4.5, and 6.5 at floral stages 9, 10, 11, and 12, respectively. The flower cap-to-calyx length ratio was consistent in the two grape cultivars, suggesting that the ratio is a morphological character representing floral development stage. This study provides a reference for determining floral development stage of the two grape cultivars. It will be useful for the determination of optimum time for microspore culture needed to generate doubled haploid lines and appropriate gibberellic acid treatment needed to induce parthenocarpic fruit development in 'Tamnara' grape.

• Applied Microscopy
• /
• v.35 no.4
• /
• pp.74-83
• /
• 2005

The ontogeny of pollen wall in Panax ginseng was studied with transmission and scanning electron microscopy from early tetrad stage until pollen maturity. Initial indication of exine development is undulation of plasma membrane for the preparation of bacular mound. The first recognizable structure of the pollen wall is the cellulosic primexine which is formed outside of the plasma membrane while microspore tetrads are still surrounded by callose wall. As development proceeds, foot-layer and baculum differentiation, callose dissolution and exine formation were progressed. During this process, sporopollenin is deposited into the exine, and then endexine development was followed. The intine, innermost pollen wall layer, is developing form hypertrophic Golgi vesicles. The thickness of exine is very even on all along the pollen wall, but intine thickness of apertural region is thicker than that of nonapertural region. Mature pollen of ginseng is $20{\mu}m$ in size, tricolpate and shows fine reticulate sculpturing.

• Proceedings of the Korean Society of Embryo Transfer Conference
• /
• 2002.11a
• /
• pp.79-79
• /
• 2002

본 연구에서는 in vitro에서 성숙된 난자의 핵성숙(Polar Body extrusion)에 소요되는 시간과 배반포 단계로의 발달능력 사이의 관계를 비교하여 조기에 발달능력을 가진 embryo를 선발할 수 있는 IVP 체계를 개발하고자 하였으며 in vitro maturation(IVM)에 따른 first polar body(PB) 형성, IVM과 IVF 시간이 oocyte의 발달에 미치는 영향과 생산된 배반포의 세포수를 평가하였다. IVM은 TCM199 배양액을 사용하였고 in vitro fertilization(IVF)은 Fer -TALP용액을 사용하였으며 in vitro culture(IVC)는 CRlaa 배양액을 사용하여 2일까지는 0.3% BSA를 3일 부터는 10%FBS와 bovine oviduct epithelial cell을 첨가하여 배양하였다. IVM 시간에 따른 PB의 출현율은 0hr(0%), 6hr(0%), 12hr(0%), 14hr(8.7%), 16hr(40.5%), 18hr(48.0%), 20hr(65%), 22(68%) 그리고 24hr(74.5%)을 보였으며 IVM 시간에 따른 cleavage 및 8cell 발달율 사이에는 유의적인 차이가 없었으나 배반포(BL) 및 8cell에서 배반포로 발달률은 18시간(BL 31$\pm$6, BL/8cell 82 $\pm$5%)에서 가장 높게 나타났으며 24시간(BL 17$\pm$2, BL/8cell 60$\pm$8%)과 유의적인 차이를 보였다(P<0.05). IVC 7일째 배반포의 총세포수와 trophoblast(TE) 세포수는 IVM 18시간(mean$\pm$S.E.; total: 131.1$\pm$34.0, TE: 97.6$\pm$29.6)에서 24시간(total: 112.2$\pm$17.5, TE: 80.1$\pm$15.6)보다 유의하게 많은 것으로 나왔으나(P<0.05) 7일째의 inner cell mass(ICM) 숫자(18hr 33.5$\pm$12.8 vs 24hr 32.1$\pm$12.0)와 8일째 ICM, TE 그리고 총 세포수에는 유의성 있는 차이가 없었다. IVM 18시간에서 PB 형성과 8cell 발달률 사이에 높은 상관성을 보였고 배반포 및 8cell에서 배반포 단계로 높은 발달률을 보였으며 생산된 배반포의 TE 숫자와 총 세포수가 유의하게 많은 것으로 나타났다. 따라서 IVM 18시간 실시하였을 경우 보다 많은 세포수를 가진 배반포 발달 가능성이 높은 embryo를 조기에 선발 가능할 것으로 사료된다.