• Journal of Ginseng Research
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• v.20 no.2
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• pp.125-132
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• 1996

To investigate the effect of Korean red ginseng (KRG) on male sexual function and serum lipid level, the results of KRG treatments were compared to placebo group. A total of 35 patients with psychogenic impotence were assigned to medication group with KRG (n=28) and placebo (n=7). KRG and placebo were given to each group for 2 months. Changes in symptoms such as frequency of coitus, morning erection, penile rigidity and tumescence were significantly higher in the group receiving KRG than placebo group. The overall therapeutic efficacies on erectile function were 67% for KRG group and 28% for placebo group (p <0.05). In the group treated with 9 tablets of KRG, there was tendency of better efficacy as compared to the group treated with 6 tablets of KRG. The level of serum high density lipid- cholesterol (HDL-cholesterol) was significantly elevated (p < 0.05) while the other serum lipid such as total cholesterol, tiglyceride and low density lipid-cholesterol (LDL-cholesterol) , were not changed after administration of KRG. This effect was observed significantly in the group in which KRG exerted its effect on sexual function(p < 0.05). From the above results, the administration of Korean red ginseng has shown to have superior of facts as compared to the placebo. The tendency of good effect was increased when a large amount of KRG was administered. The mechanism of KRG in improving sexual function would be the result of elevating the level of geum HDL-cholesterol in impotent patients. The effect of KRG was produced when the level of cholesterol was high before starting KRG medication. Therefore, the effect of KRG could be observed more intensively when the patients have high serum cholesterol level.

• Korean Journal of Biological Psychiatry
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• v.4 no.1
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• pp.108-115
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• 1997

The alcoholic neuropathies developed in approximately 34% of chronic alcoholics and the sexual dysfunction had been experienced in 8-54% of male alcoholics(Schiavi 1990). The aims of this study were to identify the prevalence of subclinical polyneuropathies and sexual disorders in alcohol dependence, and to evaluate the association between them. The nerve conduction velocity(NCV), electromyography(EMG), and pudendal somatosensory evoked potentials(SEPs) were tested for the male alcoholics(N=34) and controls(N=17 for NCV & EMG, N=25 for pudendal SEPs). The pudendal SEPs were measured by the following procedures, in which we stimulated the dorsal nerve of penis attached by the ring electrode(stimulus intensity, three times of threshold : stimulus rate, 1-4.7Hz : stimulus duration, 0.1 or 0.2msec), and recorded at the scalp(active electrode, 2cm behind Cz : reference electrode, Fz). The NCV and EMG detected signs of peripheral neuropathies in 79.4% of alcoholics. Among the alcoholics, 64.7% were abnormal on the pudendal SEPs. Among the alcoholics who revealed abnormality on EMG and NCV, 81.4% were abnormal on the pudendal SEPs, in which 51.9% were not responded. The P1 latencies of pudendal SEPs on neuropathic alcoholics were significantly delayed(p<0.05) than non-neuropathic alcoholics. There was a relative correlation between peripheral neuropathies and sexual disorders in the alcoholics. The prevalence of subclinical neuropathies and sexual disorders seemed to be much higher in alcohol dependence than expectation, and these two problems were relatively correlated, and our results suggested that the peripheral polyneuropathies were one of the prerequisites of sexual disorders.

• The Journal of the Korea institute of electronic communication sciences
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• v.12 no.6
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• pp.1197-1210
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• 2017

This study aimed to compare premature ejaculation and erectile function according to penile characteristics. 99 adult men responded to a questionnaire on penile characteristics, premature ejaculation and erectile function. In the questionnaire survey, 69 questionnaires were analyzed except missing or incomplete answers. All collected data were analyzed by independent t test, Chi-square test using SPSS 22. Glans > penis type showed significant differences in subjective premature ejaculation and objective premature ejaculation compared to Glans ${\frac{._-}{.}$ penis type (p <.05). Men with subjective premature ejaculation showed significant differences in objective premature ejaculation, treatment intent, and satisfaction compared to men without subjective premature ejaculation (p <.05). Presence of objective premature ejaculation, presence of treatment intent, and marital status were significantly different in satisfaction (p <.05). In economic status, high was significantly different in confidence for erectile function compared to middle or low (p <.05). The results of this study suggest that the premature ejaculation and erectile function according to the penile characteristic may be different and may be used as a basis for the development of an intervention program for sexual rehabilitation of men with premature ejaculation and erectile dysfunction.

• Journal of Physiology & Pathology in Korean Medicine
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• v.28 no.5
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• pp.558-564
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• 2014

The purpose of this study was to investigate the clinical results of the 10 male climateric syndrome cases while treated with Singi-hwan. All patients were treated with Singi-hwan two times a days for 5 weeks. We checked testosterone, PSA in blood, HRV and AMS questionnaire score. The questionnaire score was improved after taking Singi-hwan. Stress resistance and autonomic nervous system activity is increased, but there was no statistical significance except for ApEn. Taking Singi-hwan did not affect the serum concentration of testosterone, PSA and blood biochemical tests. The next placebo-controlled studies about late onset hypogonadism treated with Singi-hwan are needed.

• Women's Health Nursing
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• v.10 no.4
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• pp.342-350
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• 2004

Purpose: It has been suggested that approximately 40% of women between 40 and 64 years of age cease their sexual activity. The aim of this study was to establish the basic data for FSD(female sexual dysfunction) and FSD-related factors in regional urban and rural areas of Korea. Method: Three hundred twenty five women over 20 years of age and resident in regional urban and rural areas were analyzed by a visit survey with an organized questionnaire. The female sexual function index(FSFI) for measurement of sexual dysfunction was used. The significance between the degree of sexual dysfunction and characteristics of the participants was analyzed by a t-test and ANOVA test. The relationship between the degree of sexual dysfunction and related factors was analyzed by Pearson's correlation coefficient. Results: All analyzing tools including the FSFI had a high validity for measuring. The FSFI in Korean women was $19.97{\pm}4.87$ and ranged from 2 to 29. Old age, menopause, medication, no contraception usage and longer marital duration were significantly related with a lower FSFI score. Pearson's correlation coefficient revealed the significance in degrees of sexual distress (r=-.469, p=.000), sexual attitude(r=.305, p=.000) and a stressful life event(r= -.141, p=.038) with the sexual function index score. Conclusion: Women with sexual dysfunction should be evaluated for these sexual function-related factors in the history taking, and this data can be a basis for study for sexual dysfunction.

• The Korean Journal of Health Service Management
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• v.6 no.2
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• pp.201-209
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• 2012

This study was conducted to identify prevalence of sexual dysfunction and to determine factors influencing sexual dysfunction in middle aged women. The participants were 285 middle aged women. Data were collected through self-report questionnaires which were constructed to include general characteristics, FSFI (Female Sexual Function Index), sexual knowledge, sexual satisfaction. The mean score FSFI, sexual knowledge, sexual satisfaction were $14.82{\pm}5.74$, $11.25{\pm}2.67$, $45.84{\pm}8.60$, respectively. The score for sexual dysfunction showed significant difference age(F=3.52, p=.031) and health status(F=3.66, p=.013). Sexual dysfunction had significant positive correlation to sexual satisfaction(r=.46, p<001). Age and sexual satisfaction were significant predictor and accounted for 22% of the variance in sexual dysfunction middle aged women. Future sexual dysfunction management program for middle aged women should be considered their emotional, psychological, socio-environmental factors.

• The Monthly Diabetes
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• s.209
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• pp.19-24
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• 2007

당뇨병에 성기능장애가 많다는 것은 옛날부터 알려져 있지만 실제로는 그릇된 지식과 선입관에 의해 과장되게 잘못알고 있는 경우가 많다. 당뇨병이라고 모두 발기부전 환자는 아닌 것이며 정상 건강인보다 조금 높은 빈도를 보이는 것뿐이다. 식사요법과 운동요법으로 혈당조절을 잘하고 합병증을 예방하면 정상인과 다름없는 성생활을 할 수 있으며 인슐린 치료를 계속하면서 주의 깊게 혈당을 조절하고 합병증을 예방하면 60세 이후까지도 정상적인 성생활이 가능하다. 정상인도 노쇠하면 자연현상으로 언젠가는 모두 발기부전이 되므로 당뇨병환자만이 발기부전이 오는 것은 아니므로 미리 겁내고 불안해할 필요는 없는 것이다. 당뇨병환자중에는 선입관에 의해 당뇨라는 진단을 받고 정신적 충격과 그릇된 지식으로 심인성 발기부전에 빠지는 사람이 상당히 많다. 그러므로 당뇨병환자는 정상인보다 더 많은 노력을 하며 합병증의 병발을 미연에 방지하는 것이 가장 중요하다.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.3
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• pp.121-131
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• 2008

Purpose: To confirm reference value for Korean version of FSFI in selecting subjects for clinical trial of sexual dysfunction in female. Methods: Purpose of the research was explained and anonymity was guaranteed to 41 women enlisted in 6 oriental medical clinics in Seoul and Incheon province and the scores for Korean version of FSFI which participants made out themselves were analyzed so that mean value and the distribution could be investigated. Results: Mean value for Korean version of FSFI of 40 participants scored 26.32 and from this score, the participants of clinical trial were enlisted to confirm whether or not the mean value could be applied. Conclusion: The mean value for Korean version of FSFI, which scored 26 might be acceptable as a criterion for selecting participants in clinical trial of sexual dysfunction.

• Journal of Physiology & Pathology in Korean Medicine
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• v.27 no.5
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• pp.530-539
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• 2013

This study reviews the latest articles about oriental and traditional medicine treatment of male sexual dysfunction. We searched the article from 2000 to 2012 using 5 data bases. There were no restrictions on the type of publication, but articles not available in full text were excluded. The methological quality of RCT study was assessed according to Jadad scores and Cochrane's assessment of risk of bias. 18 articles were included in this study. 5 articles published in Korea, the rest were foreign articles. 9 articles were randomized controlled trial(RCT), Case-control studies were 3, case reports were 3, One group pre-post test were 3. In RCT studies, Jadad scores were generally low, and risk of selection bias and performance bias were generally high, risk of detection bias was unclear. Oriental and traditional medicine treatment is as effective as western medicine treatment for male sexual dysfunction, more rigorous oriental medicine treatment studies should be warranted.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.3
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• pp.171-189
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• 2011

Objectives: Female Sexual Dysfuction(FSD) is a common gynecologic condition and its prevalence is more higher than men. Despite its high prevalence and clinical importance, research on FSD is not enough in both of oriental and western medicine. The purpose of this study is to review research tendency of recent oriental medicine studies on FSD and to suggest the following research on FSD. Methods: We searched oriental medicine papers related to FSD published in the last 10 years(2001-2011) through Korean Medicine Gynecology Society database, KISS, RISS, NDSL, CNKI(China National Knowledge Infrastructure), and Pubmed. Results: 26 papers were searched, then 18 papers of them were related to Traditional Chinese Medicine(TCM), 8 papers of them were related to Korean Medicine(KM). In classification according to paper type, 16 papers were clinical study, 1 paper was experimental study, 2 papers were bibliographic study, and 7 papers were the other study. Then 5 papers of clinical study was Randomized Controlled Trial(RCT). Conclusion: There was a lack of oriental medicine research on FSD. On the base of this study, so further research is needed. Especially, Clinical trials such as RCT have strong objective evidence power in the viewpoint of Evidence Based Medicine(EBM) are needed.