• Title/Summary/Keyword: 선량품질관리

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Research on the use of Therapeutic Linear accelerator Quality Control using EPR/alanine Dosimeter (EPR/알라닌 선량계를 이용한 치료용 선형가속기 정도관리 활용 연구)

  • Yoon-Ha Kim;Hyo-Jin Kim;Yeong-Rok Kang;Dong-Yeon Lee
    • Journal of the Korean Society of Radiology
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    • v.18 no.3
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    • pp.239-248
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    • 2024
  • Radiation therapy uses high energy, which can have side effects on the human body. Therefore, it is important to ensure that the appropriate dose is set for irradiation and to have confidence in the radiation produced by the generator. The EPR/Alanine dosimetry system is characterized by water equivalence, dose response linearity, and low fading, which makes it useful for quality control of radiation therapy equipment. In this study, we compared the signal and dose response curves of EPR/Alanine dosimetry by mass of alanine using 6 MV energy of a LINAC. An alanine dosimeter and EPR spectrometer from Burker, and a LINAC from Elekta, were used. A dose response curve and a 1st order regression equation were constructed from the irradiated dose and the EPR signal from the alanine dosimeter. We compared the signal magnitude and dose response curve with mass and checked the confidence through the measurement uncertainty of the dose response curve. As a result, it was found that the magnitude of the EPR signal increased by about 1.3 times at 64.5 mg, and the sensitivity of the dose response curve increased as the mass increased. The measurement uncertainty was evaluated to be between 5.84 % and 8.93 %. Through this study, it is expected that the EPR/alanine dosimetry system can be applied to the quality assurance and quality control of a LINAC.

The Research Relating to QA of the Absorbed Dose in the 10 MeV E-beam Facility in Accordance with the International Standards (국제표준에 따른 10 MeV급 전자빔 조사시설의 흡수선량 품질보증에 관한 연구)

  • Ha, Tae-Sung;Ahn, Cheol;Jung, Pyeong-Hwan;Cho, Jeong-Hee;Lee, Jong-Seok;Lee, Hye-Nam;Yoo, Beong-Gyu
    • Journal of radiological science and technology
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    • v.33 no.4
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    • pp.387-394
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    • 2010
  • In the field of healthcare, the conventional sterilization treatments have been replaced by irradiation methods which are in accordance with internationally well established quality standards. The quality control in radiation sterilization assures that the absorbed dose of the irradiated material is in agreement with its requirements and standards. The electron beam irradiation requires technical assessments of more process parameters than gamma irradiation does. Korea has witnessed wide uses of electron accelerators since early 2000 but there hasn't been research experiences relating to quality system in accordance with international standards. The new large scale e-beam irradiation system with the specification of 10 MeV, 8 kW was installed and operated in 2008 by Seoul Radiology Services Co. It consists of the electron accelerator, product handling system, safety, documentation and control subsystems into an integrated system to meet the requirement of the Good Manufacturing Practice such as process quality assurance and management of product tracking records. To implement the international standard such as EN ISO11137, it is necessary to understand the purposes aimed in the standard and carry out the tests following the procedures required. This study presented the specification of the e-beam facility and showed what its design requirements and features are. The test results on a variety of process parameters were presented and validated it they are within the required limits.

Evaluation of Applicability of Perovskite Dosimeter based on CsPbBr3 Material to Quality Assurance in Radiation Therapy (CsPbBr3을 기반으로 한 Perovskite 선량계의 방사선치료 Quality Assurance에 대한 적용가능성 평가)

  • Yang, Seung-Woo;Park, Sung-Kwang
    • Journal of the Korean Society of Radiology
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    • v.16 no.3
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    • pp.211-216
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    • 2022
  • In radiation therapy, accurate Quality Assurance (QA) is required to irradiate tumor tissue while minimizing damage to normal tissue. Therefore, a dosimeter that can accurately measure radiation is needed. The purpose of this study is to develop a highly efficient radiation dosimeter with high sensitivity by applying a particle in binder method that can reduce manufacturing costs and simplify processes to perovskite materials that are cheaper and simpler to manufacture. By evaluating the response characteristics to high-energy photon, the applicability of QA dosimeter to radiation therapy was evaluated. As a result of reproducibility evaluation, RSD at 6 MV energy was presented as 1.178% and 15 MV energy was presented as 1.141%. As a result of linearity evaluation according to linear regression analysis, R2 values of 0.9999 were presented under each condition of 6 MV and 15 MV energy. It was found that the CsPbBr3 dosimeter manufactured based on the results of reproducibility and linearity evaluation is highly applicable as a QA dosimeter in the field of therapeutic radiation. The CsPbBr3 dosimeter manufactured in this study presented more than the standard performance in the evaluation of reproducibility and linearity, and it can be used as a radiotherapy QA dosimeter through improvement.

Simplistic QA for an Enhanced Dynamic Wedge using the Reversed Wedge Pair Method (역방향 조사방식을 통한 동적쐐기의 품질관리)

  • Lee Jeong Woo;Hong Semie;Suh Tae Suk
    • Progress in Medical Physics
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    • v.15 no.3
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    • pp.161-166
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    • 2004
  • A simplistic quality assurance (QA) method was designed for a Linac built-in enhanced dynamic wedge (EDW), which can be utilized to make wedged beam distributions. For the purpose of implementing the EDW symmetry QA, a film dosimetry system, low speedy dosimetry film, film densitometer and 3D RTP system were used, and the films irradiated by means of a 60$^{\circ}$ Reversed wedge pair (REWP) method. The profiles were then analyzed in terms of their symmetries, including partial treatment, which is the case of stopping it abruptly during EDW irradiation, and the measured and calculated values compared using the Cad Plan Golden Segmented Treatment Table (Golden STT). The result of this experiment was in good agreement, within 1 %, of the 'reversed wedge pair counterbalance effect'. For the QA of the effective wedge factor (EWF), the authors measured EWFs in relation to the 10$^{\circ}$, 15$^{\circ}$, 20$^{\circ}$, 25$^{\circ}$, 30$^{\circ}$, 45$^{\circ}$ and 60$^{\circ}$ EDW, which were compared with the calculated values using the correction factor derived from the Golden STT and the log files produced automatically during the process of EDW irradiation. By means of this method it was capable of check up the safety of effective wedge factor without any other dosimetry system. The EDW QA was able to be completed within 1 hour from irradiation to analysis as a consequence of the simplified QA procedure, with maximized effectiveness. Unlike the metal wedge system, the EDW system was heavily dependent on the dose rates and jaw movements; therefore, its features could potentially cause inaccuracy. The frequent simplistic QA for the EDW is essential, and could secure against the flaw of dynamic treatment that uses the EDW.

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MLC Sequencing File을 이용한 IMRT의 독립적 선량계산에 관한 연구

  • Sin, Dong-Ho;Park, Seong-Yong;Kim, Ju-Yeong;Kim, Dae-Yong;Jo, Gwan-Ho
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2005.04a
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    • pp.75-78
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    • 2005
  • IMRT를 이용한 환자치료에서 환자의 특이적 품질관리에 대한 독립적인 선량계산을 위해 치료계획용 컴퓨터로 부터 계획된 다엽콜리메이터의 배열파일(MLC sequencing file)과 계획된 MU값 및 선량계산 위치에서의 각각의 조사필드 별 기여 치 등을 얻어낸 후 MS office Excel 2000 VBA를 이용하여 간단한 분석을 통하여 MU값을 계산한 결과 계획선량과 계산선량이 ${\pm}$4% 의 선량 오차를 얻을 수 있었다.

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Prediction of Delivery Quality Assurance Via Machine Learning in Helical Tomotherapy (방사선치료 시 다양한 기계학습을 이용한 선량품질관리 결과의 예측)

  • Kyung Hwan Chang
    • Journal of radiological science and technology
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    • v.47 no.4
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    • pp.263-270
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    • 2024
  • The objective of this study was to evaluate the accuracy and impact of leaf open time (LOT) and pitch using various machine learning models on EBT film-based delivery quality assurance (DQA) performed on 211 patients of helical tomotherapy (HT). We randomly selected passed (n=191) and failed (n=20) DQA measurements to evaluate the accuracy of the k-nearest neighbor (KNN), support vector machine (SVM), naive Bayes (NB) and logistic regression (LR) models using scale-dependent metrics such as the coefficient of determination (R2), mean squared error (MSE), and root MSE (RMSE). We evaluated the performance of the four prediction models in terms of the accuracy, precision, sensitivity, and F1-score using a confusion matrix, finding the NB and LR models to achieve optimal results. The results of this study are expected to reduce the workload of medical physicists and dosimetrists by predicting DQA results according to LOT and pitch in advance.

Quality Control of Radiation Dosimetry Service (개인피폭선량 측정기관의 품질관리기준 개발)

  • Lee, Jun-Haeng;Lee, Sang-Bock;Chang, Kun-Jo;Lee, Kwang-Yong;Lee, Hyun-Koo;Kim, Hyeog-Ju;Jin, Gye-Hwan
    • Progress in Medical Physics
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    • v.20 no.4
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    • pp.253-259
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    • 2009
  • We have developed standards based on international criterions for the quality control of dose tested by the measurement institutions of individual exposure doses through improving the reliability of data on the exposure dose of individuals working in radioactive environment and securing the accuracy and reliability of individual dose measurements. Laws related to radiation dose applied to domestic institutions refer to ANSI N13.11.1993, but currently, in U.S. and some other countries the measurement of radiation doses is based on ANSI N13.11.2001 that reduced test categories and tightened the standards. We made efforts to simplify the standards and to reduce the number of dosimeters required in experiment, and avoided preventing or hindering the use of future technologies not approved under the current law such as glass dosimeter and optical stimulation dosimeter. The Quality Management Manual of Radiation Dosimetry Service, Assessment Manual of Radiation Dosimetry Service Accreditation Program, and the Personnel Dosimetry Performance. Criteria for Testing are documents applicable in supervising laboratories.

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Calibration of Optically Stimulated Luminescent nanoDot Dosimeter for 6 MV Photon Beam (6 MV 광자 빔에 대한 광자극형광나노닷선량계의 교정)

  • Kim, Jongeon;Kim, Seonghu;Lee, Hyoyeong
    • Journal of the Korean Society of Radiology
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    • v.7 no.1
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    • pp.93-98
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    • 2013
  • The purpose of this study is to investigate the calibration of an optically stimulated luminescent nanoDot dosimeter(OSLnD) to 6 MV photon beam. Dose ranges of the calibration of linear and non-linear from the analysis of dose response of the OSLnD were decided. To evaluate the accuracy of calibration equation and the calibration, the sets of the calibration and quality control dosimeter were used to make. The calibrations were performed by the linear and the non-linear in the dose range of 0~300 cGy and 20~1300 cGy, respectively. The errors of the calibration were acquired less than 0.1% respectively from the measurement of the quality control dosimeters for the calibration of linear and the non-linear. This study provides the calibration equation of the OSLnD to the 6 MV photon beam.

Development of Preliminary Quality Assurance Software for $GafChromic^{(R)}$ EBT2 Film Dosimetry ($GafChromic^{(R)}$ EBT2 Film Dosimetry를 위한 품질 관리용 초기 프로그램 개발)

  • Park, Ji-Yeon;Lee, Jeong-Woo;Choi, Kyoung-Sik;Hong, Semie;Park, Byung-Moon;Bae, Yong-Ki;Jung, Won-Gyun;Suh, Tae-Suk
    • Progress in Medical Physics
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    • v.21 no.1
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    • pp.113-119
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    • 2010
  • Software for GafChromic EBT2 film dosimetry was developed in this study. The software provides film calibration functions based on color channels, which are categorized depending on the colors red, green, blue, and gray. Evaluations of the correction effects for light scattering of a flat-bed scanner and thickness differences of the active layer are available. Dosimetric results from EBT2 films can be compared with those from the treatment planning system ECLIPSE or the two-dimensional ionization chamber array MatriXX. Dose verification using EBT2 films is implemented by carrying out the following procedures: file import, noise filtering, background correction and active layer correction, dose calculation, and evaluation. The relative and absolute background corrections are selectively applied. The calibration results and fitting equation for the sensitometric curve are exported to files. After two different types of dose matrixes are aligned through the interpolation of spatial pixel spacing, interactive translation, and rotation, profiles and isodose curves are compared. In addition, the gamma index and gamma histogram are analyzed according to the determined criteria of distance-to-agreement and dose difference. The performance evaluations were achieved by dose verification in the $60^{\circ}$-enhanced dynamic wedged field and intensity-modulated (IM) beams for prostate cancer. All pass ratios for the two types of tests showed more than 99% in the evaluation, and a gamma histogram with 3 mm and 3% criteria was used. The software was developed for use in routine periodic quality assurance and complex IM beam verification. It can also be used as a dedicated radiochromic film software tool for analyzing dose distribution.