• Title/Summary/Keyword: 선량증가비

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A Monte Carlo Study of Dose Enhancement according to the Enhancement Agents (몬테칼로 기법을 이용한 방사선 선량증가 물질에 따른 선량증가 효과 평가)

  • Kim, Jung-Hoon;Kim, Chang-Soo;Hwang, Chulhwan
    • Journal of radiological science and technology
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    • v.40 no.1
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    • pp.93-99
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    • 2017
  • Dose enhancement effects at megavoltage (MV) X and ${\gamma}-ray$ energies, and the effects of different energy levels on incident energy, dose enhancement agents, and concentrations were analyzed using Monte Carlo simulations. Gold, gadolinium, Iodine, and iron oxide ($Fe_2O_3$) were compared as dose enhancement agents. For incident energy, 4, 6, 10 and 15 MV X-ray spectra produced by a linear accelerator and a Co-60 ${\gamma}-ray$ were used. The dose enhancement factor (DEF) was calculated using an ICRU Slab phantom for concentrations of 7, 18, and 30 mg/g. The DEF was higher at higher concentrations of dose enhancement agents and at lower incident energies. The calculated DEF ranged from 1.035 to 1.079, and dose enhancement effects were highest for iron oxide, followed by iodine, gadolinium, and gold. Thus, this study contributes to improving the therapeutic ratio by delivering larger doses of radiation to tumor volume, and provides data to support further in vivo and in vitro studies.

대두의 방사선 감수성에 관한 연구(예보)

  • Shin-Han Kwon;Kun-Hyuk Im;Byeo-Jeong Kim
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.2
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    • pp.46-49
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    • 1964
  • 1. 본 시험에 사용된 선량범위내에서는 기건종자에 의한 Thermal neutron이나 X-ray의 처리가 발아율에 크게 영향을 미치지 못하였는데 Fast neutorn 처리종자의 발아율은 선량의 증가에 따라 거의 직선적 저하를 보였다. 2. 선량의 증가에 따라 기형엽발생율은 증가하였으며 특히 Fast neutron에서는 동일 flux일망정 Thermal neutron 조사구에 비해 발생율은 높다. 3. 저선량에서의 기형엽출현은 유식물기에서만 봇 수 있으며 성장함에 따라 회복한다. 이는 정상세포와 이상세포간의 분열속도의 차에 기인되는 상 싶다. 4. 같은 선량에서는 Fast neutron이 Thermal neutron에 비해 그 영향력이 크다는 것이 확실하며 이는 Energy의 차에서 오는 결과이다. 5. 일반적으로 선량의 증가에 따라 성숙이 연장되는 경향이 있었으며, 반면에 아주 희귀하기는 하나 개화와 성숙이 촉진되는 고체도 발견되었다. 6. 선량의 증가에따라 다소 왜소화되기는 하나 저선량에서는 오히려 유의성은 없으나 초장이 증가하였다. 7. 생육초기와 생육종기에 있어서의 선량에 따르는 초장에 대한 영향은 그 초기에 있어서 더 현저하며 성장함에 따라 회복되는 경향을 보인다. 8. 발아와 생육에 별 지장이 없이 재배할 수 있는 선량범위는 Thermal neutron에서 $1O^13$ N/$cm^2$, Fast neutron에서 5$\times$$1O^12$N/$cm^2$ 이하이면 무난할 것이며, X-ray는 본 시험에 이용한 32 Kr 이상에서도 이용에 지장이 없을 것이다.

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Evaluation of Dose Enhancement by Gold Nanoparticles using Mathematical Head Phantom (금 나노입자를 활용한 두부 모의피폭체에서의 선량증가 효과 평가)

  • Hwang, Chulhwan;Park, Eun-Tae;Kim, Jung-Hoon
    • The Journal of the Korea Contents Association
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    • v.16 no.8
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    • pp.477-483
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    • 2016
  • The effect of dose enhancement was evaluated using Snyder head phantom, dependence on size of gold nanoparticle and material concentration in megavoltage X, ${\gamma}$-ray. Monte Carlo simulation using MCNPX was used for 4, 6, 10, 15 MV and Co-60 ${\gamma}$-ray. Described the tumor in Snyder head phantom, gold nanoparticle of 25, 75, 125nm diameter was inserted inside tumor. Concentration of dose enhancement material was used for 5, 15, 25 mg/g and dose enhancement factor was calculated on the basis of the no dose enhancement material. The lower incident energy and the higher concentration of material were that high dose enhancement factor is indicated. The size of gold nanoparticle had relatively high dependence on lower incident energy and higher concentration of material. It will increase dose inside the tumor, and be additional effect of use of gold nanoparticles in radiation therapy.

A Monte Carlo Study of Dose Enhancement with kilovoltage and megavoltage photons (몬테칼로 기법을 이용한 kV, MV X선에서의 선량증가 효과 비교 평가)

  • Hwang, ChulHwan;Im, In-Chul;Kim, Jung-Hoon
    • Journal of the Korean Society of Radiology
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    • v.11 no.2
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    • pp.87-94
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    • 2017
  • Monte Carlo simulations were used to assess dose enhancement effects for 60-, 90-, 120-, and 150-kV X-rays, and for 6- and 15-MV X-rays. The MCNPX code was used for a computer simulation of the ICRU slab phantom, and gold, gadolinium, and iron oxide (Fe2O3) were employed as dose enhancement agents. In consideration of the buildup region of the incident energy, agent concentrations of 5, 10, 15, and 20 mg/g were inserted on the surface of the phantom at a depth of 5 cm. Based on baseline values obtained in the absence of dose enhancement agents, a quantitative analysis was performed by evaluating depth-dependent changes in the absorbed energy and the dose enhancement factor (DEF). A higher concentration of dose enhancement agents led to a greater dose enhancement effect with iron oxide, gadolinium, and gold in descending order. For kilovoltage (kV) X-rays, as the incident energy was decreased and as the energy became closer to the ionization potential of the atoms in the enhancement agent, the dose enhancement effect increased. In the megavoltage (MV) X-ray range, dose enhancement was higher at 6 MV compared with 15 MV. However, the overall dose enhancements were significantly lower compared to the results obtained with kV X-rays.

Research on the Actual Condition of Mammograpgy and Space Scattered Dose in Mammography Room (유방촬영의 실태와 유방촬영실의 공간산란선량에 관한 조사 연구)

  • Lee, In-Ja;Park, Kye-Yeon;Kim, Sung-Soo
    • Journal of radiological science and technology
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    • v.29 no.1
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    • pp.21-28
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    • 2006
  • I made inquires about mammographic equipments and circumstances of mammography rooms in the 64 medical facilities in areas of Seoul and Kyong Gi Do. Moreover I had experments about exposure dose with patients and radiologic technologists. so there is the data indicated follows. 1. There are inclined to improve in quality and function of mammographic equipments, it has been proven that s/f system exchanged to DR system. 2. It is certain that the number of examinations are becoming increasingly significant. 3. The Space Scattered Dose of mammography rooms are much more larger than portable equipments. 4. I worry about the affection of expose dose about Space Scattered Dose of mammography room. 5. There is need of study how to cope with the situation about increasing exposure dose of radiologic technologists in small space and numeruous number of examinations.

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Study on the Change of Absorbed Dose and Image Quality according to X-ray Condition of Detector in Digital Radiography(DR) (Digital Radiography(DR)에서 검출기의 X선 조건에 따른 흡수선량 및 영상화질 변화에 관한 연구)

  • Hwang, Jun-Ho;Jeong, Jae-Ho;Kim, Hyun-Soo;Lee, Kyung-Bae
    • The Journal of the Korea Contents Association
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    • v.17 no.9
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    • pp.99-106
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    • 2017
  • This study focused on the issue that when a diagnostic detector is found to have a defect, a patient would be exposed to radiation and image quality would be degraded. Though dose analysis, an experiment was conducted to evaluate detector performance as Signal to Noise Ratio (SNR) and Contrast to Noise Ratio (CNR). Absorbed dose, SNR and CNR were measured using a dosimeter and a tissue equivalent phantom. The experiment was conducted to compare whether the dose value shown after being attached to the back side of the phantom matches the dose value attached behind the detector, where in the conditions of skull, chest and abdomen were set at 75 kVp, 25 mAs, 110 kVp, 8 mAs, and 80 kVp, 20 mAs, respectively. As a result, there was a difference in that the dose values attached to the back side of the detector were 0.004 mGy, 0.006 mGy, 0.003 mGy, whereas those of the back side of the phantom were 0.006 mGy, 0.016 mGy, 0.017 mGy. In order to match both values, the condition was increased and SNR and CNR also increased from 88.32, 88.10, 4.09, 1.63, 87.94, 79.97 to 93.87, 93.75, 4.91, 4.03, 92.02, 84.92. Though this study, we found that when a detector is found to have a aging, it shortens the life of equipment and increases the dose of a patient, also the improvement effect of image quality is inadequate.

Germination properties of Wheat and Barley Exposed to Gamma Irradiation (감마선 조사된 밀과 보리의 검지를 위한 발아특성 비교)

  • 오경남;김경은;양재승
    • Journal of Food Hygiene and Safety
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    • v.16 no.2
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    • pp.139-144
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    • 2001
  • A 5-day germination test is applicable to detect biological changes in irradiated wheat and barley at low doses. Seeds were irradiated at below 0.5 kGy, husked and placed on distilled water-moistend filter paper in a covered Petri-dish. Water was supplied everyday. To evaluate the growth rate, the length of shoots and roots was measured during germination. In wheat, the shoots of all samples grew well during 5 days, but the shoot length and the daily growth extent decreased with increasing doses. The roots of non-irradiated wheat showed the highest daily growth extent during 5 days and the root length was over 20 mm at 3rd day. In barley, the growth of shoots and roots was retarded at 0.3 kGy or more after 3 days. It was concluded that if the root length was 20mm or longer within 3 days, wheat and barley were identified as non-irradiated. The germination test was proved a promising screening method for the detection of irradiated wheal and barley.

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Effects of Gamma Radiation on the Germination, Growth and Enzyme (peroxidase and catalase) Activities of Old Vegetable Seed (묵은 채소 종자의 발아와 생육 및 효소활성에 미치는 $\gamma$선의 영향)

  • 김재성;백명화;김동희;이영근;정규회
    • Korean Journal of Environmental Biology
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    • v.19 no.3
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    • pp.205-210
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    • 2001
  • To determine the effect of low dose gamma radiation on the germination and enzyme activities, seeds of Chinese cabbage (Brassica compestris L. cv. Hanyoreum) and radish (Raphanus sativus L. cv. Chungsukoungzoung) were irradiated at the dose of 2-50 Gy. The germination rate of irradiation group was higher than that of the control. Especially it was highest at the early stage. The germination rate of Chinese cabbage was high at 2 Gy and 8 Gy irradiation group and that of radish was high at 2 Gy, 6 Gy and 10 Gy irradiation group. Growth of both seedlings of Chinese cabbage and radish increased positively in low dose irradiation group. The height of Chinese cabbage was noticeably high at 4 Gy and 10 Gy irradiation group and that of radish at 6 Gy irradiation group. The protein contents of seedlings from seeds irradiated with the low dose gamma radiation was higher than the control, especially at the early stage. The enzyme activities of seedlings from seeds irradiated with the low dose gamma radiation was high at 4 Gy and 10 Gy irradiation group. These results suggest that the germination, growth and enzyme activities of old vegetable seeds could be promoted by the low dose gamma radiation.

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A Study on Dose Response of MAGAT (Methacrylic Acid, Gelatin Gel and THPC) Polymer Gel Dosimeter Using X-ray CT Scanner (X-ray CT Scanner를 이용한 MAGAT (Methacrylic Acid, Gelatin Gel and THPC) 중합체 겔 선량계의 선량 반응성 연구)

  • Jung, Jae-Yong;Lee, Choong-Il;Min, Jeong-Hwan;Kim, Yon-Lae;Lee, Seong-Yong;Suh, Tae-Suk
    • Progress in Medical Physics
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    • v.21 no.1
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    • pp.1-8
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    • 2010
  • In this study, we evaluated the dose response of MAGAT (Methacrylic Acid Gelatin gel and THPC) normoxic polymer gel dosimeters based on the X-ray CT scanner. To perform this study, we determined the proper ratio of the gel composition and acquired X-ray scan parameters. MAGAT gel dosimeters were manufactured using MAA (MethacrylicAcid) and gelatin of various concentration, irradiated up to 20 Gy. We obtained the 20 CT images from the irradiated gel dosimeters by using on a Phillips Brilliance Big Bore CT scanner with the various scan parameters. This CT images were used to determine the $N_{CT}$-dose response, dose sensitivity and dose resolution As an amount of MAA and gelatin were increase, the slope and intercept were increase in each MAGAT gel dosimeter with various concentration of the $N_{CT}$-dose response curve. The dose sensitivity was $0.38{\pm}0.08$ to $0.859{\pm}0.1$ and increased were amount of the MAA was increased or the gelatin was decreased. However, the change of gelatin concentration was very small compare to MAA. The Dose resolution ($D_{\Delta}^{95%}$) varies considerably from 2.6 to 6 Gy, dependent on dose resolution and CT image noise. The slope and dose sensitivity was almost ident verywith the variation of the tube voltage, tube current and slice thickness in the dose response curve, but the noise (standard deviation of averamalg CT number) was decreased when the tube voltage, tube current and slice thickness are increase. The optimal MAGAT polymer gel dosimeter based on the CT were evaluated to determine the CT imaging scan parameters of the maximum tube voltage, tube current and slice thickness (commonly used in clinical) using the composition ratio of a 9% MAA, 8% gelatin and 83% water. This study could get proper composition ratio and scan parameter evaluating dose response of MAGAT normoxic polymer gel dosimeter using CT scanner.

방사선 조사 건고사리의 습열조리 중 연화속도

  • 성태화;김미리
    • Proceedings of the Korean Society of Postharvest Science and Technology of Agricultural Products Conference
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    • 2003.10a
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    • pp.149.1-149
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    • 2003
  • 방사선에 의한 식품 저장은 이미 그 건전성과 경제적 타당성이 인정되어 세계 여러나라에서 실용화되고 있다. 고사리(Pteridium aquilinum)는 참고사리과에 속하는 다년생 양치식물로서 봄철에 어린잎과 줄기를 삶아 물에 담구었다가 건조시켜 저장하였다가 이용하고 있다. 현재 유통되고 있는 건고사리는 수확, 건조 및 저장 중에 비위생적인 관리 등에 의해 미생물의 증식 및 해충의 발생 등으로 품질이 크게 저하되어 저장상 많은 어려움을 안고 있다. 선행연구에서 방사선 조사된 건고사리는 불림시 연화현상이 나타났으므로, 본 실험에서는 Co-60감마선을 건고사리에 조사하여 습열조리 조건에 따른 연화 특성을 분석하였다. 즉, 건고사리에 조사선량을 0, 3, 5, 7kGy로 달리 하여 조사하였고 조리온도, 조리 시간에 따른 연화정도 및 연화에 따른 활성화 에너지를 분석하였다. 결과 조사선량이 높을 수록 경도는 대조구에 비해 유의적으로 감소하였는데 조리온도, 시간 및 조사선량이 증가할수록 감소하였다. 활성화에너지는 조사선량이 증가함에 따라 감소하여 건고사리의 가열 조리시 에너지가 감소 됨 이 확인되었다.

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