• Title/Summary/Keyword: 서울대학교병원

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Diffuse Leptomeningeal Glioneuronal Tumor with FGFR1 Mutation in a 29-Year-Old Male (29세 남성에서 발생한 FGFR1 돌연변이를 동반한 미만성 연수막성 신경교종)

  • Minsu Kim;Ki Rim Lee;Gheeyoung Choe;Kihwan Hwang;Jae Hyoung Kim
    • Journal of the Korean Society of Radiology
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    • v.84 no.4
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    • pp.970-976
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    • 2023
  • This study reports on diffuse leptomeningeal glioneuronal tumor (DL-GNT) in a 29- year-old male. DL-GNT is a rare central nervous system (CNS) tumor mostly seen in children and only few cases have been reported in adult patients. Our patient presented with a chronic headache that lasted for five months. MR imaging showed mild hydrocephalus, multiple rim-enhancing nodular lesions in the suprasellar cistern, diffuse leptomeningeal enhancement in the lumbosacral area, and multiple small non-enhancing cyst-appearing lesions not suppressed on fluid attenuated inversion recovery (FLAIR) images in the bilateral basal ganglia, thalami, and cerebral hemispheres. Under the impression of germ cell tumor with leptomeningeal seeding, the patient underwent trans-sphenoidal tumor removal. DL-GNT was pathologically confirmed and FGFR1 mutation was detected through a next-generation sequencing test. In conclusion, a combination of leptomeningeal enhancement and multiple parenchymal non-enhancing cyst-appearing lesions not suppressed on FLAIR images may be helpful for differential diagnosis despite overlapping imaging features with many other CNS diseases that have leptomeningeal enhancement.

Extraordinary Response of Metastatic Pancreatic Cancer to Chemotherapy (항암 치료에 좋은 반응을 보였던 전이성 췌장암 증례)

  • Shin, Dong Woo;Kim, Jinkook;Lee, Jong-chan;Kim, Jaihwan;Hwang, Jin-Hyeok
    • Journal of Digestive Cancer Research
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    • v.7 no.1
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    • pp.22-25
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    • 2019
  • A 58-year-old woman presented with right flank and back pain for one month. After undergoing an abdominal computed tomography (CT), she was referred to our hospital. The abdominal CT showed a hypodense pancreatic tail mass with multiple retroperitoneal lymph node metastases. Positron emission tomography-computed tomography (PET-CT) scan showed high 18F-FDG uptake in pancreatic tumor and enlarged lymph nodes. Endoscopic ultrasound fine needle aspiration (EUS-FNA) revealed adenocarcinoma, which stained strongly in hENT1 (human equilibrative nucleoside transporter 1) on immunohistochemistry. She received gemcitabine 1,000 mg/m2 + nanoparticle albumin-bound paclitaxel 125 mg/m2 as a palliative chemotherapy. Follow-up abdominal CT and PET-CT after 4 cycles of chemotherapy showed that both pancreatic mass and the metastatic retroperitoneal lymph nodes were nearly disappeared. We report a case of 58-year-old female with metastatic pancreatic cancer who had a dramatic response to palliative chemotherapy (gemcitabine plus nanoparticle albumin-bound paclitaxel).

Education needs for clinical nursing practice using an Importance-Performance Analysis and Borich needs assessment model: Focused on nurses in the general wards of a tertiary hospital (Importance-Performance Analysis와 Borich 요구도 분석 방법을 활용한 임상간호실무 교육 요구도: 일개 상급종합병원 일반병동 간호사 대상)

  • Lee, Mira;Kim, Jiyoung;Kim, Boyeon;Park, Yooyun;Han, Jiyoo;Lee, Seunghee;Lee, Hyunju
    • The Journal of Korean Academic Society of Nursing Education
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    • v.29 no.2
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    • pp.124-137
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    • 2023
  • Purpose: This study's aim was to confirm the importance and performance of the clinical practice of nurses working in the general wards of a tertiary hospital and to analyze their educational needs. Methods: The study employed a descriptive research design, and a self-reported questionnaire was developed and used for nurses in a tertiary hospital. Data were collected from July 22 to July 29, 2022, analyzed by an independent t-test, paired t-test, and one-way ANOVA for the importance and performance of each clinical nursing practice according to general characteristics, and then a post hoc verification was performed by Scheffé's test. An Importance-Performance Analysis and Borich needs assessment model were used to analyze clinical nursing education needs. Results: Clinical nursing practice performance showed a significant difference according to length of total clinical career, time working in current department, and preceptor experience. According to the results of the Importance-Performance Analysis, neurological evaluation, and nursing intervention, artificial respirator and high-flow oxygen inhalation nursing, chemotherapy, emergency nursing, and cardiopulmonary resuscitation were identified as belonging to the "concentrate here" quadrant. All these items ranked in the top 10 in the Borich needs assessment model. Conclusion: Based on these results, the current education system should be reviewed, and short and long term education strategies based on educational needs should be established to strengthen the competence of nurses.

Primary Rectal Syphilis Mimicking Lymphoma: A Case Report and Literature Review (림프종으로 오인될 수 있는 원발성 직장 매독: 증례 보고와 문헌 고찰)

  • Hyunyoung Bae;Jungheum Cho;Hyuk Jung Kim;Suk Ki Jang;Hee Young Na;Jin Ho Paik
    • Journal of the Korean Society of Radiology
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    • v.85 no.4
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    • pp.801-806
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    • 2024
  • Primary rectal syphilis is a rare disease that can be misdiagnosed as lymphoma or other rectal cancers on sigmoidoscopy or CT. Here, we report a case of primary rectal syphilis mimicking rectal malignancy in a 23-year-old male who presented with a rectal mass and multiple lymphadenopathies. In this case report and literature review, we focused on the CT findings and endoscopic observations of primary rectal syphilis. Infectious diseases, such as rectal syphilis, should be considered in the differential diagnosis of young patients with unusual rectal lesions and disproportionately extensive lymphadenopathies.

Effects of Resilience, Family Support, and Spiritual Well-Being on Posttraumatic Growth in Patients with Lung Cancer Undergoing Chemotherapy (항암화학요법을 받은 폐암 환자의 회복탄력성, 가족 지지, 영적 안녕이 외상 후 성장에 미치는 영향)

  • Moon, Ha Young;Nam, Ki Sook;Oh, Hye Won;Cho, Yeon Soo;Choi, Ju Yeon
    • Journal of Korean Clinical Nursing Research
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    • v.30 no.2
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    • pp.147-156
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    • 2024
  • Purpose: The purpose of this study is to confirm the effect of resilience, family support, and spiritual well-being on posttraumatic growth(PTG) in lung cancer patients undergoing chemotherapy. Methods: The study collected data from January 20 to July 6, 2023 on 124 lung cancer patients who were admitted to hospital of C university in Seoul and received chemotherapy treatment. Patients were asked to complete a questionnaire consisting of general characteristics, disease characteristics, resilience, family support, spiritual well-being and PTG. Data were analyzed using t-tests, One-way ANOVA, Pearson's correlation and multiple regression analysis. Results: The mean score for PTG in lung cancer patients was 55.17, resilience was 72.46, family support was 49.00, and spiritual well-being was 53.50. Significant positive correlations were found for PTG with resilience (r=.62, p<.001), family support (r=.40, p<.001) and spiritual well-being (r=.47, p<.001). Factors contributing to PTG of lung cancer patients were resilience (β=.50, p<.001), spiritual well-being (β=.20, p=.008), and gender (β =.14, p=.043). Conclusion: This study aims to provide basic data for the PTG intervention program by identifying factors affecting the PTG of lung cancer patients. It is necessary to develop new nursing intervention programs to improve PTG for patients with lung cancer based on strategies to enhance resilience and spiritual well-being.

Analysis of the Rate of Discrepancy between Preliminary Reports by Radiology Residents and Final Reports by Certified Radiologists for Emergency Radiology: Studies in a University Hospital (대학병원 응급 영상검사에서 영상의학과 전공의 가판독과 전문의 최종 판독 간의 불일치 발생률 분석)

  • Younbeom Jeong;Cheong-Il Shin;Hwan Jun Jae;Jung Hoon Kim;Jin Wook Chung
    • Journal of the Korean Society of Radiology
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    • v.82 no.5
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    • pp.1186-1195
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    • 2021
  • Purpose In the adult emergency department of a university hospital, we investigated the frequency of major discrepancies between the preliminary reports by radiology residents and the final reports by certified radiologists. Materials and Methods Based on CT and MRI scans obtained between December 2016 and November 2019, we selected cases with diagnoses or treatment plans that could be changed due to discrepancies between preliminary and final reports and classified them by the type of discrepancy. We also examined the distributions of the major discrepancies and stratified them by residents' working time zone, experience, and subspecialty. Results Based on the 72137 preliminary reports evaluated, 1348 tests (1.9%) showed major discrepancies. Most of the major discrepancies were false negatives (72.0%), followed by misdiagnosis (26.3%) and false positives (1.7%). Acute findings (87.2%) were more common than non-acute findings (12.8%). The major discrepancy rate increased toward the second half of the 24-hour shift, with the highest rate of 2.9% occurring between 2 am and 4 am. The major discrepancy rate did not vary with experience, and it varied from 0.6% to 4.5% for each subspecialty. Conclusion The major discrepancy rate was less than 2%, and it increased with longer working hours during a 24-hour shift.

산업보건기관 탐방기 - 가톨릭대학교 서울성모병원 직업환경의학센터

  • Hong, A-Reum
    • 월간산업보건
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    • s.362
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    • pp.52-55
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    • 2018
  • 직업병을 홀대하던 시절이 있었다. 일을 하면서 그 일로 인해 병이 걸렸음에도 불구하고 그 누구 하나 대책을 마련하기 힘들었던 시절. '직업병'이라는 개념이 서서히 사회 표면으로 꺼내기 시작해 지금까지 산업보건의 역사를 함께하는 곳, 가톨릭대학교 서울성모병원 직업환경의학센터에는 건강하게 일하고 싶은 근로자들의 바람이 담겨있다.

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Clinical Use of Virtual Reality in Addiction (중독 질환에서 가상현실기술 적용의 임상적 유용성)

  • Lee, Jung-Young;Jung, Duk Hwan;Choi, Jung-Seok
    • Journal of Korean Academy of Addiction Psychiatry
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    • v.18 no.1
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    • pp.17-22
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    • 2014
  • Virtual reality (VR) provides an immersive and interactive 3-dimensional system, which allows an individual to become immersed in a computer-generated situation. VR technology has been administered in the exposure-based treatment of a variety of psychiatric disorders, including acrophobia, fear of flight, and post-traumatic stress disorder. Furthermore, VR systems have also been developed for the use of research and treatment in addiction. They might have advantages in cue exposure therapy, by increasing the salience of cues, as well as assessments of cue reactivity in addiction. This article summarizes the application of VR in the field of psychiatry. More importantly, it suggests the possibilities of clinical use of VR technology, in the treatment of addiction.

A feasibility study of audio-video communication application using mobile telecommunication in inter-hospital transfer situations (병원 간 전원 상황에서 이동통신망을 이용한 음성화상정보통신 애플리케이션의 유용성에 관한 연구)

  • Jeong, Joo;Kim, Tae-Han;Kang, Saee-Byel
    • The Korean Journal of Emergency Medical Services
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    • v.23 no.1
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    • pp.125-134
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    • 2019
  • Purpose: The aim of this study was to evaluate the usefulness of video communication with medical staff located at a remote location, through a communication application connected to a long term evolution (LTE) mobile communication network in a moving ambulance. Methods: In this study, we recruited patients who were transferred by mobile intensive care unit ambulance from one hospital to another. In the moving ambulance, the information of the patient was transferred to a physician using the application in real time. Recorded video files were evaluated by emergency physicians with experience in video direct medical control. Results: A total of 18 patients were evaluated, and the average score was 5.9 out of a possible 9. It was expected that applying the use of the technology to actual clinical sites would enable the sites to provide assistance. Conclusion: In this study, we confirmed the possibility of benefiting from the clinical field when using the video-audio communication application which is connected to the remote location in real time through the current LTE mobile communication network in the ambulance.

Diagnosis of Scoliosis Using Chest Radiographs with a Semi-Supervised Generative Adversarial Network (준지도학습 방법을 이용한 흉부 X선 사진에서 척추측만증의 진단)

  • Woojin Lee;Keewon Shin;Junsoo Lee;Seung-Jin Yoo;Min A Yoon;Yo Won Choi;Gil-Sun Hong;Namkug Kim;Sanghyun Paik
    • Journal of the Korean Society of Radiology
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    • v.83 no.6
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    • pp.1298-1311
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    • 2022
  • Purpose To develop and validate a deep learning-based screening tool for the early diagnosis of scoliosis using chest radiographs with a semi-supervised generative adversarial network (GAN). Materials and Methods Using a semi-supervised learning framework with a GAN, a screening tool for diagnosing scoliosis was developed and validated through the chest PA radiographs of patients at two different tertiary hospitals. Our proposed method used training GAN with mild to severe scoliosis only in a semi-supervised manner, as an upstream task to learn scoliosis representations and a downstream task to perform simple classification for differentiating between normal and scoliosis states sensitively. Results The area under the receiver operating characteristic curve, negative predictive value (NPV), positive predictive value, sensitivity, and specificity were 0.856, 0.950, 0.579, 0.985, and 0.285, respectively. Conclusion Our deep learning-based artificial intelligence software in a semi-supervised manner achieved excellent performance in diagnosing scoliosis using the chest PA radiographs of young individuals; thus, it could be used as a screening tool with high NPV and sensitivity and reduce the burden on radiologists for diagnosing scoliosis through health screening chest radiographs.