• Journal of Digital Convergence
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• v.9 no.2
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• pp.141-152
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• 2011

The data center has become an increasingly important part of most business operations. An increasing demand for computation has led to increasing industry energy consumption. Therefore, higher-than-normal rates of energy efficiency have become a core issue in the life cycle of data center. In this paper, we proposed the framework of level diagnosis for green data centre that can be used to diagnose the levels of capability maturity model. This framework contains the 5 key areas such as construction, air-conditioning, electricity, information technology, organization and indicators that can be applied as basic level diagnosis guide for green data center.

• Journal of Life Science
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• v.21 no.2
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• pp.316-321
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• 2011

Generation of tryptophan-derived metabolites by indoleamine 2,3-dioxygenase (IDO) is a potent immunoregulatory mechanism in T cell responses. However, the mechanism remains unclear. We showed that 3-hydroxyanthranilic acid (3-HAA), the most potent metabolite, selectively induced apoptosis in activated T cells, but not in resting T cells. This was not associated with cell cycle arrest. We found that TRAIL expression was selectively induced in activated T cells by treatment of 3-HAA. Blockade of the TRAIL: DR4/DR5 pathway significantly inhibited 3-HAA-mediated T cell death. Our data suggest that TRAIL-induced apoptosis is involved in the mechanism of 3-HAA-mediated T cell death.

• Proceedings of the Korea Water Resources Association Conference
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• 2022.05a
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• pp.400-400
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• 2022

관로 내 빈번히 발생하는 수격압의 발생은 관망 구조물에 피로가 누적되고 관벽에 손상을 발생시켜, 관로 내 누수가 다양한 형태로 생성된다. 관 내 누수가 발생되는 경우 관 내부의 수격압의 발생 시 생성되는 부압으로 인하여 외부 물질이 관으로 흡수되거나 혼합되어 스케일과 미생물의 생성되는 등 관 내의 수질에 악영향을 끼치며 마찰을 증가시켜 통수능이 감소하고 관리에 추가적인 비용을 발생시킨다. 이러한 영향을 방지하기 위해 관 내에서 생성되는 누수를 탐지하기 위하여 수격압을 발생시켜 압력파를 분석하거나 추적을 수행하는 여러 가지 연구들이 수행되었다. 본 연구에서는 현장 관망과 연결된 100A 대구경 관로에 관로 수압 발생장치를 연결하여 기존의 수격압을 발생시켜 분석하는 방법 대신 안전하고 용이한 방법인 압력파를 주입하여 실험을 수행하였다. 실험을 통해 획득한 데이터를 시간상에서 분석하고 Fourier 변환을 통한 빈도상 분석과 Wavelet 분석으로 신호주기에서 누수가 미치는 영향을 파악하였다. 실험 결과에서는 누수에 의한 영향으로 반사파가 직접적으로 변형되는 형태보다 시스템 전체에서 반영되어 수두가 감쇠되는 형태로 나타났다. Fourier 변환을 통해 무누수 조건과 누수조건의 비교에서 누수의 유무에 따른 신호의 형태가 차이를 보였다. 앞선 연구들에서의 누수의 특정한 위치를 찾아내는 형태 대신 신호처리 후 분석을 통해 시스템 전체에서 일어나는 감쇠를 통해 누수 존재 유무를 판별하고자 한다.

• Journal of Life Science
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• v.29 no.4
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• pp.447-454
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• 2019

Fat accumulation in adipocytes occurs through the process of adipogenesis in which preadipocytes differentiate into adipocytes. Obesity is a metabolic disorder caused by excessive accumulation of fat in the body, which increases the incidence of cardiovascular diseases, hypertension, type 2 diabetes, hyperlipidemia, and various cancers. Recently, inhibition of adipocyte differentiation was shown to be a potential antiobesity strategy. In this study, the inhibitory effect of dichloromethane fractions from Illicium verum Hooker fil. water extract on the differentiation of 3T3-L1 preadipocytes to adipocytes was investigated. Dichloromethane fractions from I. verum Hooker fil. significantly inhibited adipocyte differentiation when applied during the adipocyte differentiation process, as assessed by measuring fat accumulation using Oil-red O staining. In addition, dichloromethane fractions from I. verum Hooker fil. reduced important adipogenic transcription factors, such as CCAAT/enhancer binding protein ${\alpha}$ ($C/EBP{\alpha}$), $C/EBP{\beta}$, and peroxisome proliferator activated receptor ${\gamma}$ ($PPAR{\gamma}$). The expression of FAS and LPL, which are terminal differentiation markers of mature adipocytes, was also reduced in the 3T3-L1 adipocytes treated with dichloromethane fractions from I. verum Hooker fil. In addition, the treatment significantly inhibited mitotic clonal expansion, which is essential for adipocyte differentiation, by arresting the G1 phase of the cell cycle. Taken together, these results suggest that dichloromethane fractions from I. verum Hooker fil. may be a natural material with antiobesity effects.

• Journal of fish pathology
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• v.33 no.2
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• pp.145-151
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• 2020

The whiteleg shrimp Litopenaeus vannamei can survive in a wide range of salinity (1-40 psu). However, such variation, particularly at low salinity (1-5 psu), can affect various physiological changes such as survival rates, non-specific immunity and disease resistance. In this study, growth, non-specific immunity and disease resistance were measured following simultaneous oral feeding and addition of probiotic microbes into culture water for 73 day period. The salinity of the culture water was maintained at 3 psu by periodical salt additions. The result shows that survival rate increased significantly (5.6 vs. 15.4%) after 73 day rearing. Significant increases were identified in reactive oxygen species (ROS) production and phenol oxidase (PO) activity. However, superoxide dismutase (SOD) activity was not influenced. When the shrimp was artificially challenged with Vibrio alginolyticus, slight mortality reduction was observed in the probiotics-treated group (100 vs. 79%). In conclusion, the production of cultured whiteleg shrimp at low salinity might be increased by probiotics survivable at low salinity levels.

• Journal of Marine Life Science
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• v.5 no.2
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• pp.51-57
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• 2020

Disinfection and maintenance of rearing water in aquaculture is an essential element for the prevention of fish diseases. This is especially important in recirculating aquaculture systems (RAS) in which fish are reared at high density using recycled water. In this study, tilapia was reared in two different RAS (one with plasma generator - PW system, another without plasma generator - No PW system). In plasma treated group, UVT% of water was improved clearly, and the number of heterotrophic bacteria decreased significantly after 40 days. Total weight gain of tilapia in PW system was significantly higher, and other growth indicators were also relatively higher although not statistically significant. In addition, the fish in PW system had a 100% survival rate, and there were no histological differences between fish from both systems. Fish did not seem to be affected by the toxicity of ROS. In conclusion, it is expected that plasma water can effectively deactivate fish pathogens and improve the quality of rearing water.

• Journal of agriculture & life science
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• v.43 no.3
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• pp.1-6
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• 2009

This study has been carried out to measure the extent of damage for Witches' broom of cherry trees planted as street trees along the 5.16 road around the Halla Mountain. This study is expected to provide effective measures to prevent the infection of witches' broom. Among the cherry trees examined, almost all the trees of 40 years or over were severely infected. Those around 30 years old were infected as well, though they showing medium level of disease symptoms. However, cherry trees of less than 23 years were observed to be healthy without showing any symptoms. Cherry trees spontaneously growing within 30m width of the 5.16 road in the section from Sanchondan to Kyunwolak were less severely infected by Witches' broom (Taphrima waesneri), though there was a difference by tree age.

• Research in Plant Disease
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• v.29 no.3
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• pp.251-257
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• 2023

In order to examine the pathogenicity of Alternaria dauci, the causal agent of carrot leaf blight, it is necessary to standardize sporulation conditions to ensure the optimal quantity and quality of spore inoculum. Therefore, in this study, the effects of the growth medium, aeration treatment, and UV treatment with 12-hr photoperiod on the sporulation of A. dauci KACC42997 were investigated. A. dauci KACC42997 was pre-cultured for 7 days in a potato dextrose agar medium at 25℃ in the dark condition. When the pre-culture, after removing aerial mycelia, was re-incubated for 5 days, with simultaneous aeration treatment and 12-hr cycle UV treatment at 20℃, the largest number of spores was produced. One hundred seventy isolates of A. dauci were isolated from major carrot growing regions such as Pyeongchang, Gumi and Jeju and tested for sporulation under the conditions established in this study. Except for 20 strains, all strains produced spores. Statistically significant differences in the extent of sporulation were found among local populations of A. dauci isolates, but no difference was observed in their pathogenicity on carrots.

• Journal of Plant Biotechnology
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• v.36 no.1
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• pp.7-12
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• 2009

This study was conducted to establish the optimal suspension culture system for both the propagation of embryogenic cells (ECs) and the induction of somatic embryos (SEs) of Kalopanax septemlobus. The proliferation rate of ECs was reduced as the inoculum density was increased; the highest rate was obtained when 0.1 g/100 ml of cells was initially inoculated. According to the analysis of cell growth pattern and cell growth cycle (G1, Sand G2/M), the cell growth started in 5 days culture initiation, grew rapidly until 15 days and then decreased gradually. Distinctive changes of the cell growth cycle by the culture periods was also observed; the growth cycle was doubled from initial 5.6% to 11.7% of S stage in 5 days culture and then reached in stable stages again. Therefore, the results indicated that a 15-day-cycle was the optimal culture period for the propagation of the ECs through the suspension culture. Furthermore, the cell inoculum density was also important for the induction of SE; more than 65% of SEs at the torpedo stage was induced by using the low level of cell inoculum (0.5 g/L), while the higher inoculum densities were rapidly reduced the proportion of SEs at that stage. Although the higher inoculum density delayed the development of SE, it did not affect the proportion of SEs at the globular and heart stage. In conclusion, this study showed that the suspension culture of the Kalopanax septemlobus ECs through the control of inoculum density was an efficient way for both the propagation of ECs and the induction of SEs, suggesting that the development of this system might help to reduce the culture period for the somatic embryo production.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10b
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• pp.424-426
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• 2004

웹 기술이 발달할수록 사회 전반의 패러다임 변화속도는 빨라지고, 사용자의 요구 사항과 웹 프로그램 내부의 복잡성은 증가한다. 또한 콘텐츠의 생명 주기는 짧아지고, 웹 프로그램의 구조 변경과 유지보수가 많아지게 된다. 따라서 동적인 변화에 빠르게 대처할 수 있는 웹 프로그램 기술이 더욱 요구되고 있다. XML은 계층적 구조를 갖고 있으면서도 구조적 변경이 가능하고, 다른 형태로의 변환이 용이하다. 본 논문에서는 이런 장점을 이용하여 개발 기간을 단축시킬 수 있는 방법의 하나로, XML을 기반으로 하는 웹 프로그램 개발 지원 서버를 이용해 쉽고 간편하게 웹 서버 프로그램을 개발하고, 유지보수 할 수 있도록 하는데 중점을 두고 웹 기반의 XML 트리를 설계하고 구현하였다. XML 트리는 파싱뿐만 아니라 계층적 구조를 이루고 있어 접근성이 우수하고, XML 스키마와 XML 스타일시트 작성에도 않은 도움을 줄 수 있을 것으로 기대된다.