• Korean Journal of Poultry Science
• /
• v.50 no.4
• /
• pp.283-291
• /
• 2023

Long-chain fatty acids (LCFAs) are vital in cellular compartments, primarily regulating lipid metabolism. Fatty Acid-Binding Proteins (FABPs) facilitate LCFA transport, lipid synthesis, storage, and act as signaling molecules influencing various pathways, including inflammation. FABP4, in particular, is linked to vascular and cardio-related diseases, and it plays a role in macrophage-mediated inflammatory responses. Previous studies have identified FABP4 as not only a representative biomarker for lipogenesis but also as having correlations with immune responses. This study aims to investigate the regulation of the chicken FABP4 (chFABP4) gene by toll-like receptor 3 (TLR3) activation and determine the signaling pathways that are involved in chFABP4 transcriptional regulation. We analyzed the transcriptional regulation of chFABP4 in TLR3-stimulated DF-1 cells. The results showed that chFABP4 was up-regulated upon stimulation with polyinosinic-polycytidylic acid (PIC), a TLR3 ligand. Notably, chFABP4 transcription was independently regulated in the NF-κB signaling pathway. It was up-regulated in p38 inhibition, demonstrating that the p38 signaling pathway might suppress the transcription of chFABP4 within TLR3-activated DF-1 cells. In contrast, chFABP4 expression was down-regulated in JNK signaling pathway inhibition, suggesting the positive regulation of JNK signaling pathway for chFABP4 transcription in DF-1 cells in response to TLR3 activation, consistent with findings in macrophages. MEK pathway inhibition resulted in a similar regulation to NF-κB signaling. These results suggest that each MAPK contributes differentially to the transcriptional regulation of chFABP4 by in DF-1 cells in response to TLR3 activation.

• Journal of Industrial Convergence
• /
• v.21 no.11
• /
• pp.117-124
• /
• 2023

This study is a descriptive research study to determine the relationship between nursing students' emotional intelligence, communication competence, interpersonal competence, and adaptation to college life, and to identify factors that adaptation to college life. The subjects of the study were 173 nursing students attending a university in G City, and data collection was conducted from September 10 to October 10, 2022 Descriptive statistics, t-test, ANOVA, Pearson correlation coefficient, and multiple regression analysis were performed on the collected data using SPSS 25.0 program. The results showed a significant positive correlation between emotional intelligence(r=.760, p<.001), communication competence(r=.600, p<.001), and interpersonal competence(r=.451, p<.001). Factors that have a significant impact on adaptation to college life include emotional intelligence(𝛽=.543, p<.001), communication competence(𝛽=.433, p=.001), and interpersonal competence(𝛽=.283, p<.031). The total explanatory power of these variables on adaptation to college life was 59.9%, and emotional intelligence was confirmed to be the main influencing factor.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.43 no.6
• /
• pp.785-791
• /
• 2023

Risk management is essential for preventing accidents arising from uncertainties in TBM tunnel projects, especially concerning managing the risk of TBM tunnel collapse, which can cause extensive damage from the tunnel face to the ground surface. In addition, prioritizing risks is necessary to allocate resources efficiently within time and cost constraints. Therefore, this study aimed to establish a TBM risk database through case studies of TBM accidents and determine a risk priority for TBM tunnel collapse using the Bayes theorem. The database consisted of 87 cases, dealing with three accidents and five geological sources. Applying the Bayes theorem to the database, it was found that fault zones and weak ground significantly increased the probability of tunnel collapse, while the other sources showed low correlations with collapse. Therefore, the risk priority for TBM tunnel collapse, considering geological sources, is as follows: 1) Fault zone, 2) Weak ground, 3) Mixed ground, 4) High in-situ stress, and 5) Expansive ground. In practice, the derived risk priority can serve as a valuable reference for risk management, enhancing the safety and efficiency of TBM construction. It provides guidance for developing appropriate countermeasure plans and allocating resources effectively to mitigate the risk of TBM tunnel collapse.

• Journal of the Korean Society of Marine Environment & Safety
• /
• v.29 no.6
• /
• pp.525-535
• /
• 2023

In thi study, we unveil the intricate interplay among picophytoplankton (0.2-2 ㎛) communities, warming surface water temperatures, and major inorganic nutrients within the southwestern East Sea from 2003-2022. The observed surface temperature rise, reflecting global climate trends, defies conventional seasonal patterns in temperate seas, with highest temperatures in summer and lowest in spring. Concurrently, concentrations of major dissolved inorganic nutrient display distinct seasonality, with peaks in winter and gradually declining thereafter during spring. The time course of chlorophyll-a concentrations, a proxy for phytoplankton biomass, reveals a typical bimodal pattern for temperate seas. Notably, contributions from picophytoplankton exhibited a steady annual increase of approximately 0.5% over the study period, although the total chlorophyll-a concentrations declined slightly. The strong correlations between picophytoplankton contributions and inorganic nutrient concentrations is noteworthy, highlighting their competitively advantageous responsiveness to the shifting nutrient regime. These findings reflect significant ecological implications for the scientific insights into the marine ecosystem responses to changing climate conditions.

• Korean Journal of Culture and Social Issue
• /
• v.14 no.2
• /
• pp.41-61
• /
• 2008

This study was performed to investigate the North Korean defectors's depression through the CES-D and a projective test simultaneously. So 40 North Korean defectors and 40 South Koreans participated in this study. The results are the following. First, the North Korean defectors demonstrated more higher CES-D scores than the South Koreans, while there were not significant differences in the Rorschach depression-related indexes, DEPI, CDI, S-CON between two groups. Second, at the analysis of the sex difference effect, women among the North Korean defectors showed the most high CDI index scores. In addition, we analyzed the mean differences between two groups for morbid content, shading response, achromatic response, human movement response, form dimension response, Lamda, and the number of total response. However, there are not significant differences between two groups for those variables, except for form dimension(FD) response. It suggested the probability that the North Korean women defectors could experience more psychological distress underlyingly than the North Korean men defectors. Third, most importantly, the correlation between CES-D and DEPI in the Rorschach test was significantly different in the two groups(the North Korean defectors and the South Koreans). In conclusion, the self-report of the North Korean defectors on depression could be exaggerated. So we should be cautious to interpret the self report results of the North Korean defectors.

• Korean Journal of Culture and Social Issue
• /
• v.8 no.1
• /
• pp.17-40
• /
• 2002

The purpose of this study is to investigate the differences in the traffic environments and driving behaviors in 5 regions of Korea. Data were collected through the survey research from 1387 passenger car drivers in 14 locations in Korea. The main findings of this research are as followings: First of all, There were significant differences in traffic environment factors(road topography, construction, road & safety facilities, pedestrian behaviors, surrounding drivers) among 5 regional areas. When we examined drivers factors, there were significant differences among 5 metropolitan areas on wearing seat belt, most of constructions related to drink driving, speed-limit violation. There were many differences in driving habits, intentions, behaviors including wearing seat belt, driving after drinking according to metropolitan area, and also in case of speed-limit violation and careless driving behavior. These results suggested that there are many differences in traffic environments and driver's behaviors among regional areas. These result suggests that traffic safety policy and practice should be prepared based upon the peculiarities of regional area. We discussed these resulte in terms of the regional traffic policy and the suggestions for future studies were added.

• The Journal of the Convergence on Culture Technology
• /
• v.9 no.5
• /
• pp.357-365
• /
• 2023

Purpose : The purpose of this study was to examine the effect of nursing students' experience of verbal violence on major satisfaction, practice satisfaction, and nursing professionalism. Data were collected 237 237 3rd and 4th grade nursing students from two nursing colleges located in G and P cities, and the structured questionnaire was analyzed The results of the study showed that major satisfaction was significantly different according to gender (F=1,50, p<.001), grade (F=-2.38, p<.001), and motivation for choosing nursing (t=6.79, p<.000). appeared to have a difference. The experiences of verbal violence were related to major satisfaction (r=-.298, p<.001), practice satisfaction (r=.-.348, p<.001), and professionalism (r=.-.4071, p<.001). It was found that there was a statistically significant negative (-) correlation. Factors influencing the subject's experience of verbal violence include professionalism (β=.305, p<.001), satisfaction with major (β=259, p<.001), and satisfaction with practice (β=142, p=.003). ), and the explanatory power of these variables was 25.9%. It is necessary to develop a program that can cope with verbal violence of nursing students.

• Korean Journal of Culture and Social Issue
• /
• v.12 no.1
• /
• pp.55-79
• /
• 2006

This study is interested in aberrant driver behaviour. The aim of this study is to investigate the effect of error and lapse on driving behaviour of elderly drivers. In order to estimate the errors and lapses, 'Driver Behaviour Questionnaire(DBQ) was used and tested with 883 drivers. Among them 175 of young drivers(younger than 25) and 150 of elderly drivers(older than 65) answered their driving patterns; driving history, annual mileage, the frequency of committing traffic violation, and experience of accident within 5 years. Elderly driver's data were collected by face to face interview. The factors of aberrant driver behaviour were analyzed and the DBQ score was compared by the age. The aberrant driver behaviour was consisted of 3 factors; violations, errors and lapses. Elderly driver's DBQ score was lower than young driver's. Elderly and young drivers showed longer driving history. were in low DBQ score group. Elderly drivers had high error score and young drivers had high violation score. Young driver's aberrant driving behaviour was associated with annual mileage, the frequency of committing traffic violation. Elderly driver's aberrant driving behaviour was associated with annual mileage, experience of accident. Specially elderly drivers, whose violation, error, lapse score was high answered more committing experience of accident within 5 years.

• Journal of the Korean Crystal Growth and Crystal Technology
• /
• v.33 no.6
• /
• pp.288-293
• /
• 2023

To optimize the process parameters of laser powder bed fusion process to fabricate the high density STS316L alloy, the effect of laser power, scanning speed and hatching distance on the relative density was studied. Tensile properties of additively manufactured STS316L alloy using optimized parameters was also evaluated according to the build direction. As a result of additive manufacturing process under the energy density of 55.6 J/mm³, 83.3 J/mm³ and 111.1 J/mm³, high density STS316L specimens was suitably fabricated when the energy density, power and scan speed were 83.3 J/mm³, 225 W and 1000 mm/s, respectively. The yield strength, ultimate tensile strength, and elongation of STS316L specimens in direction perpendicular to the build direction, show the most competitive values. Anisotropic shape of the pores and the lack of fusion defects probably caused strain localization which result in deterioration of tensile properties.

• Journal of Industrial Convergence
• /
• v.22 no.2
• /
• pp.153-159
• /
• 2024

This study is a descriptive research study to determine the relationship between middle-aged women's social support, resilience and quality of life, and to identify factors that affect quality of life. The participants were 162 middle-aged women in G City. Data was collected from May 10 to June 10, 2023. Data were analyzed through descriptive statistics, t-test, one-way ANOVA, Pearson's correlation coefficient, and multiple regression using SPSS 25.0 program. The social support was 3.36±0.38, resilience was 3.39±0.42, and quality of life was 3.18±0.50. Quality of life was positively correlated with social support(r=.502, p<.001), resilience(r=.530, p<.001). Factors that have a significant impact on quality of life include resilience(β=.422, p<.001), social support(β=.412, p<.001) and health status(β=.212, p=.001). The total explanatory power of these variables on quality of life was 39.2%. Therefore, it is necessary to develop effective programs and strategies to improve the quality of life of middle-aged women by improving their resilience, social support, and health status.