• Korean Journal of Fisheries and Aquatic Sciences
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• v.33 no.1
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• pp.75-78
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• 2000

The present study was conducted for the data of toxicity and taste components of the pufferfish, Sphoeroides annulayus (bull's eye fuller), transported from Mexico. All other parts including muscle and skin were nontoxic ranging below $10\;{\mu/g$ except gonad, The amounts of IMP and ADP were $5.6\;{\mu}mol/g\;and\;2.7\;{\mu}mol/g$, and the ratio to the total ATP and its related compounds was $41.1{\%}$. The great portion of free amino acids in the muscle of the puffer was occupied by L-glycine, L-alanine, L-anserine, L-threonine and L-valine. Their amounts were $233.5 mg/100 g, 169.0 mg/100 g, 149.1 mg/100 g, 135.7 mg/100 g and 132.3 mg/100 g$. Their concentration ratio to total free amino acids were $14.28{\%},\;10.33{\%},\;9.12{\%},\;8.30{\%}\;and\;8.09{\%}$, respectively. The content was $50.12{\%}$ of the total free amino acids. In addition, the amounts of taurine and L-histidine were 119.3mg/100 g and 14,7 mg/100 g.

• Journal of the KSME
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• v.20 no.5
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• pp.379-386
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• 1980

지금까지 서론에서는 화석연료와 기타 여러 대체에너지의 한계성에 비추어 원자력(특히 핵분열 에너지)에너지 이용의 불가피성을 지적하였다. 이어서 본론에서는 원자력발전에 관한 가장 기초 적인 개념을 소개하고, 또 원자로기술의 현황과 원자력발전소의 안전성에 대하여서도 간단히 고경하였다. 원자력발전소는 방사능을 누출하고 폐열을 방충하기 때문에 잠재적 위험성을 갖고 있음은 부인할 수 없다. 그러나 모든 에너지 전환장치는 폐기물을 내어놓게 마련이다. 특히 석 탄화력발전소는 C $O^{1}$, $SO^{2}$ , 분진등을 방출한다. 각종연구결과와 실 예를 종합하여 보면 공해요소 방출면에서 뿐만아니라, 자원착용 및 국가경제적 측면에서도 원자력발전은 재래식 석탄및 석유화력발전보다 훨씬 우수함을 알 수 있다. 원자력발전시설과 모든 관계기술도 앞으로 시간이 경과함에 따라 계속 진보되어 열효율의 증대는 물론, 안전시설과 그타 방사능 폐기물의 처리법등도 완전히 개량될 것이다. 현시점에서 단기적으로는 경수로(및 경수로)와 이에 수반되는 모든 기술과 시설을 계속 개량하여야 할 것이며, 장기적으로는 증식로와 같은 보다 더 개량된 원자로의 이용으로 열효율의 증가를 구하여 폐열 오염의 문제도 감소시키고, 천연산 핵분열물 질도 함께 절약하여야 할 것이다. 환언하면 장기적으로는 증식로와 경수로(및 중수로)의 병립체를 위한 준비작업을 서둘러야 할 것으로 본다.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.30 no.1
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• pp.148-151
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• 1997

A cossurid polychaete, Cossura brunnea Fauchald, 1972, was newly recorded in Korean fauna. Family Cossuridae is firstly known to in Korean coastal waters. The specimens of the species were collected in the muddy sand bottom. The species was described and illustrated. The key to family was provided.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.4
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• pp.132-147
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• 2007

Purpose: We aimed at reviewing the studies of the acupuncture treatment for women related to pregnancy. Methods: We referred to PubMed by searching words of pregnancy and acupuncture and limited experimental method to randomized control trial. Results: We found 52 articles in 32 journals, which were divided into 3 parts: treatment for symptoms during pregnancy, treatment for symptom related to delivery and treatment for symptoms related to surgical operation for IVF-ET. In this study, articles on hypermesis gravidarum were the greatest in number and acupuncture for pain control related to pregnancy are most frequently appearing in terms of symptoms. Besides acupuncture treatment, acupressure band and acupressure were used for hyperemesis gravidarum, common acupuncture for low back pain in pregnancy and acupuncture or moxibustion to resolve breech presentation. Conclusion: In this study, acupuncture seems to be an efficacious means of reducing symptoms related to pregnancy and improving the quality of life of pregnant women.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.709-713
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• 2009

최근의 주안점이 되고 있는 것 중의 과연 우리나라 하천의 하상이 높아지고 있는지 낮아지고 있는지에 대한 논의이다. 하상이 높아지고 있다고 하는 주장은 다목적 댐이나 하구둑에 의해 이른바 홍수가 플러싱이 안되어 하상이 계속 쌓이고, 그에 따라 홍수 위험이 가중되었다고 주장하는 사람들이 있다. 반면에, 오히려 1960년대부터 1970년대 초까지 산에 숲이 없어 토사 유출이 심해 하상이 쌓였으나, 그 이후 산림녹화가 되고 주요 하천에 대댐이 건설되어 하상이 깎이기 시작하였고, 지금은 주요 댐 상류 이외에는 대부분 하상이 낮아졌다고 추론하는 사람들도 있다. 본 연구는 이를 실증적으로 규명하기 위해 낙동강의 구간별 하상 변화를 조사하고 그 경향성을 분석한 것이다. 그런데, 최심 하상의 비교는 국부적인 변화에 지나치게 민감하여 그 대표성을 띄기 힘들며, 100년 빈도 홍수에 대한 평균 하상은 실제의 저수로 하상 보다 지나치게 높은 하상을 나타내는 문제를 보였다. 따라서 기존의 최심 하상이나 100년 빈도 홍수위에 대한 평균 하상의 비교가 아닌 연평균 홍수위에 근거한 평균 하상 개념을 제안하고, 이를 토대로 하상 변화를 분석하였다. 연평균 홍수위에 대한 평균 하상을 이용한 결과, 낙동강에서는 1983${\sim}$1993년 사이에는 대규모 하상 저하는 없었으나, 중류부인 고령과 왜관 구간(하구에서 150${\sim}$200 km 구간)에서 작은 규모의 하상 저하가 발생하였다. 1993${\sim}$2005년 사이에는 하상 저하의 규모가 더욱 커져서 120${\sim}$200 km 구간에서는 평균적으로 2${\sim}$3 m, 최대의 하상 저하 5 m 정도의 하상 저하가 발생하였고, 그 상류부인 200${\sim}$240 km 구간에서는 1${\sim}$2 m 정도의 비교적 작은 규모의 하상 저하가 발생하였다. 그러나 내성천 합류점 상류 구간 (240 km 이상의 구간)에서는 하상 상승과 하강은 거의 대부분 국부적인 현상에 머물고 있으며, 대규모 하상 변동이 없다. 이러한 낙동강 하상 저하의 주 원인은 대규모 골재 채취임을 밝혀내었다.

• The Journal of Korean Obstetrics and Gynecology
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• v.21 no.1
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• pp.83-98
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• 2008

Purpose: This study was performed to determine the inhibitory effect of Soyosangagamhwajae(SYG) on melanin synthesis in B16F10 mouse melanoma cell. Methods: The Inhibitory effects of Soyosangagamhwajae(SYG) on melanin synthesis were determined by in-vitro assay. To elucidate inhibitory effects of SYG on melanin synthesis, we determined the melanin release in B16F10 cell. And to investigate the action mechanism, we assessed the gene expression of tyrosinase, TRP-1, TRP-2. PKA, $PKC{\beta}$ in B16F10 cell. Results: 1. SYG significantly inhibited melanin-release in B16F10 cell. 2. SYG significantly inhibited mushroom tyrosinase activity in vitro. 3. SYG significantly suppressed the expression of tyrosinase in B16F10 cell. 4. SYG significantly suppressed the expression of TRP-1, TRP-2 in B16F10 cell. 5. SYG significantly suppressed the expression of PKA, $PKC{\beta}$ in B16F10 cell. Conclusion: From these results, it may be concluded that SYG has the antimelanogenetic effect.

• The Journal of Korean Obstetrics and Gynecology
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• v.19 no.3
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• pp.151-173
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• 2006

Purpose : This study was performed to evaluate anti-thrombotic and anti-inflammatory effects of BokbangHongdeungPaejangSan water extract (BHPS). Methods : BHPS was investigated using cultured cells and a murine models. As for the parameters of inflammation, levels of several inflammatory cytokines and chemical mediators which are known to be related to inflammation were determined in mouse lung fibroblast cells (mLFC) and RAW 264.7 cells. Results : In experiment of anti-thrombotic effect, BHPS inhibited the platelet aggregation induced by ADP and epinephrine, and inhibited pulmonary embolism induced by collagen and epinephrine. BHPS increased Platelet number and fibrinogen amount, and shortened PT and APTT in thrombus model induced by dextran. In experiment of anti-inflammatory effect, BHPS inhibited IL-1${\beta}$, IL-6, TNF-${\alpha}$, COX-2 and NOS-II mRNA expression in a concentration-dependent manner in RAW 264.7 cell line, and inhibited significantly NO production at 50, 100 ${\mu}g/ml$, and also inhibited ROS production in a concentration-dependent manner. BHPS inhibited IL-1${\beta}$, IL-6 and TNF-${\alpha}$ production significantly in serum of acute inflammation-induced Balb/c mice, and decreased IL-1${\beta}$, IL-6 and TNF-${\alpha}$ production in spleen tissue, but increased IL-1${\beta}$, IL-6 and TNF-${\alpha}$ production in liver tissue. BHPS increased survival rate at the 3th day in ICR mice with lethal endotoxemia induced by LPS. Conclusion : These results suggest that BHPS can be used for treating diverse female diseases caused by thrombosis and inflammation such as endometriosis, pelvic pain, cervicitis, pelvic inflammatory disease and pelvic tuberculosis and so forth.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.2
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• pp.1-24
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• 2007

Purpose : These experiments were undertaken to evaluate the effect of adminis tration of JokyungSan on ovarian functions and differential gene expressions related cell viabilities caspase-3, MAPK and MPG in female mice. Methods : We administered the JokyungSan to 6-week-old female ICR mice for 4, 8, or 12 days. The female mice were injected PMSG and hCG for ovarian hyperstimulation. We chose the caspase-3 for cell apoptosis, MAPK and MPG genes for cell viability and DNA repair. To compare the differences, we set a control group treated with plain water at the same volume by the same way. Results : In case of 4-day administration of JokyungSan, the mean number of total ovulated oocytes and the number of morphologically normal oocytes increased significantly compared to a control group. The administration of JokyungSan, were beneficial effect of embryonic development in preimplantation period and play a role of prevention of cell apoptosis and DNA damages and also increased cell proliferation resulted in ovarian functions. Conclusion : From our results suggested that the medication of JokyungSan has beneficial effect on reproductive functions of female mice via prevention of cell apoptosis and DNA damaging and promotion of cell proliferation.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.3
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• pp.173-183
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• 2010

Purpose: To estimate the effect of oriental treatment on recurrent pregnancy loss, a retrospective analysis was done. Methods: Sixty-eight pregnant women at the $\bigcirc\bigcirc$ oriental clinic, Korea, from January 2005 to May 2009 diagnosed as recurrent pregnancy loss were included in this study. The sixty-eight patients received oriental treatment such as acupuncture, moxibution, herbal acupuncture and herbal prescriptions, divided into two groups: Group A- live birth(N=58) and Group B- abortion(N=10). The maternal age, parity, menstrual history, gynecological history and period of treatment were compared. To find out factors affecting the success of birth, we performed binary logistic regression analysis(SPSS ver. 14.0 for windows). Results: The live birth rate was 85.3%. The maternal age, parity, menstrual history, gynecological history and period of treatment were not different between two groups. Logistic regression analysis showed that the significant factors predicting the occurrence of miscarriage were advanced maternal age(${\geq}35$)(P=0.005, Odds Ratio[OR]=3.809, 95% Confidence Interval[95%CI]: 1.514-9.585) and suffering from gynecological problems(P=0.044, OR=4.048, 95%CI: 1.037-15.801). Conclusions: The results suggest that oriental treatment has effectiveness on recurrent pregnancy loss. Further study will be needed.

• The Journal of Korean Obstetrics and Gynecology
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• v.24 no.2
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• pp.13-32
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• 2011

Objectives: This study was performed to elucidate the effects of Danchisoyo-san (DS) on cell damage and gene expression in UVB-exposed dermal fibroblast. Methods: To demonstrate the inhibitory effects of DS on aging of the skin, we used human dermal fibroblast(F6) and UVB light(30 mJ/$cm^2$) was used to damage to dermal fibroblast. We measured the nitrite production, LDH release, and gene expression in UVB-irradiated dermal fibroblast to elucidate the actionmechanism of DS. Also, we evaluated the amount of increased PICP, TIMP-1 in dermal fibroblast. PICP, TIMP-1 concentration was measured using EIA kit, and gene expression (MMP-1, procollagen, c-fos, c-jun, NF-kB, Bcl-2, Bcl-xL, iNOS) were determined using real-time PCR. Results: 1. DS inhibited LDH-release, nitrite production in UVB-irradiated dermal fibroblast. 2. DS suppressed the gene expression of MMP-1 in UVB-irradiated dermal fibroblast. 3. DS increased the gene expression of procollagen in UVB-iradiated dermal fibroblast. 4. DS suppressed the gene expression of c-jun, c-fos, NF-kB, iNOS in UVBirradiated dermal fibroblast. 5. DS increased the gene expression of Bcl-2 in UVB-iradiated dermal fibroblast. 6. DS increased the cell proliferation of dermal fibroblast. Conclusions: From the results, we concluded DS increases the cell proliferation and collagen synthesis in dermal fibroblast. So we suggest that DS has the antiwrinkle effects.