• 대한의용생체공학회:의공학회지
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• 제25권1호
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• pp.77-82
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• 2004

다양한 한국인의 표준 뇌를 완성하기 위해 영상 획득의 기준을 마련하고, 획득된 한국인의 뇌 영상 데이터들과 피검자들의 개인 정보들을 저장하고 관리하는 데이터베이스 관리 시스템의 개발이 본 연구의 목적이다. 해부학적 영상 획득을 위해 SNR과 CNR이 우수하고 영상획득시간도 줄일 수 있는 3D MP-RAGE 기법을 선택하였고, 최적의 영상 획득을 손잡이 검사, 상태-특성 불안척도 검사, A 유형 성격 검사, 자기평가 우울척도 검사, 사상체질 검사 간이정신 진단검사, 지능진단 검사, 성격요인 검사를 질문지로 수행한 후 그 결과를 저장하고 관리 할 수 있도록 하였다. 또한 본 시스템은 피검자의 영상 정보 및 개인 정보의 저장, 삽입, 삭제, 검색, 출력 기능뿐만 아니라 Access 권한 기능, ODBC와의 연결 설정도 자동으로 수행되도록 개발하였다. 개발된 시스템은 다양한 한국인의 영상 정보와 개인 정보를 저장, 관리 할 수 있기 때문에 다양한 한국인의 표준뇌를 완성하는데 큰 기여를 할 수 있을 것이다.

• 대한한방부인과학회지
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• 제32권2호
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• pp.29-49
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• 2019

Objectives: This study was a methodological study to verify the reliability and validity and to make a diagnosis of a diagnostic tool for climacteric and postmenopausal syndrome pattern identification (CaPSPI). Methods: This study was conducted from June 1, 2018 to October 18, 2018 with ${{\bigcirc}{\bigcirc}}$ University Korean Medicine Hospital IRB's approval (2018-3). To make a diagnosis using CaPSPI, we decided the cut-points for the tool. Three professors of ${{\bigcirc}{\bigcirc}}$Korean Medical University conducted pattern identification diagnosis. The result is marked from 0 to 3, 0 is 'No', 1 is 'Slightly Yes', 2 is 'Yes' and 3 is 'Very Yes'. And if two or more professors' diagnoses are the same, we took the diagnoses as a diagnostic criteria. The decision of pattern by three experts converted to 0-1 scores in two ways. In "method 1", if the diagnosis was zero points, the score was 0 (have no such identification), and the rest was 1 (have such identification). In "method 2", if the diagnosis was zero or 1 point, the score was 0, and the rest was 1. After that, intraclass correlation was calculated for experts agreement. And logistic regression was conducted. A response variable was the results of the experts' diagnosis and an explanatory variable was the results of the pattern identification diagnostic tool. Results: The diagnosis of the three experts showed excellent concordance of more than 0.794 and showed a significant correlation with the diagnostic tool. Both 'Method 1' and 'Method 2' showed statistically significant effects with the diagnosis of 3 experts and the results of the diagnostic tool. The frequency of cumulative pattern identification diagnosis in 'Method 1' and 'Method 2' were found to be 578 occasions and 203 occasions, respectively. The average number of pattern held by participants in 'Method 1' and 'Method 2' were found to be 5.26 and 1.85, respectively. In both "Method 1" and "Method 2," the yield frequency of liver qi depression was the highest, and the frequency of kidney yin deficiency and liver-kidney yin deficiency was relatively high. Conclusions: Based on the above results, it is thought that, in diagnosis using CaPSPI of menopausal women, 'method 1' could be used for the health diagnosis and prevention, 'method 2' could be used for the pattern diagnosis. On the conclusion, CaPSPI is thought to be available for pattern diagnosis of menopause women.

• 한국한의학연구원논문집
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• 제8권1호
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• pp.75-92
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• 2002

The purpose of this study was to investigate the difference of the morphological diagram by Sasang Constitutions and compare with Huh's morphological diagram, a theory based on the Four Cho Theory(四焦設) by Lee Je-Ma. We classified the Sasang Constitutions of 104 Korean College Students(average age 23.81) using QSCC II. Before measuring of morphologic diagrams, we exert the subjects to take supine position on the bed, and make it a rule that our staffs mesure each people directly. The 50% of the total subjects was Soeumin, 26.9% was Soyangin and 23.1% was Taeumin, our study shows the higher percentage than the other studies in Soeumin. The results as follows ; In the cases of man, Taeumin have more developed Low-Middle Cho(the interval between stomach line and Navel line) than other constitutions, whereas Soeumin has more developed Low cho(the interval between Navel line and Ilium line). In the cases of woman, there is no significant difference of Huh's morphology diagram among three Sasang constitutions. We analyzed the difference of obesity among sasang constitutions, and we found that the BMI(Body Mass Index$(Kg/m^2)$) of Taeumin was significantly higher than other constitutions in male. But there was no significant difference among Sasang constitutions in female. We have not found the exact accordance between the real measurement and Huh's Theory. But for man, there are several statistically significant results, indicating the usefulness of the Huh's Morphological Diagramming theory on the discriminating ability of Sasang Constitutions Classificaton. So this results suggest that the use of the Huh's theory should be improved in the classification of the Sasang Constitutions, considering the difference of morphology by sex.

• 대한예방한의학회지
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• 제12권2호
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• pp.131-143
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• 2008

This study aims at finding out the correlation between sasang constitution diagnosis using QSCCII which is self reporting questionnaire and sasang constitution diagnosis using iridology. In this study, 131 adult male and female participated as testees. The survey on questionnaires of QSCCII were carried out and then photos of irises of the participants were taken. The data from QSCCII was computed in WIN QSCCII version and they were translated into sasang constitution. For iris photos, the iris specialized camera with 1,300,000 picture elements was used, and then the iris photos were also read by computer. The correlation rate between QSCCII sasang constitution and iris sasang constitution was 52.4%, where kappa coefficient shows 0.323, which gives meaningful result statistically. And thus, the result can be used as a reference in sasang constitution diagnosis. For iridology to be served as a tool for sasang constitution diagnosis, criteria need to be developed for more concrete iris sasang constitution diagnosis in the future. And also comparative research is required among sasang constitution professionals and its iridological correlation of Sasang constitution carried out on more various group of people.

• 한국한의학연구원논문집
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• 제12권2호통권17호
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• pp.103-113
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• 2006

Objectives we intended to know how much did it relate with the results between the instruments of diagnosis by using methods of three factors - QSCCII, PSSC(Phonetic System for Sasang Constitution)-2004, and body measurement which are usually used in diagnosing the Sasang Constitution in clinics Methods We diagnosed Sasang constitution through QSCCII, PSSC(Phonetic System for Sasang Constitution)-2004, Body measurement as a dignosis factors and we used Kappa coefficient to estimate simularity between diagnosis factors, and SPSS 12.0K to analyze data Results and conchusions 1. The orders of agreement statistics are different in the currency of Sasang Constitution diagnosis, Soeum-in was highest and Taeum-in lowest in the the fricency of Sasang Conctitution Diagnosis in the QSCCII, Soeum-in was highest Soyang-in lowest in the PSSC and Taeum-in highest, Soyang-in lowest in the body measurement so, we analogized incorrection in Sasang Constitution Diagnosis 2. Among 443 subjects, 156 (35.3%) had same dignosis in three Sasang Constitution factors. It means agreement statistics among factors of diagnosis are very low, so it is absolutely nessessary to research connection among those, especially Soyang-in part 3. Totally, it is not robust to apply these factors on Sasang Constitution diagnosis, especially agreement statistics between two kinds of Sasang Constitution diagnosis as $0.358{\sim}0.380$. However, we can have a possibility the more we use Sasang Constitution dignosis factors, the higher the agreement statistics is, through the ascending of agreement statistics as $0.526{\sim}0.592$, among three kinds of Sasang Constitution diagnosis To evaluate accuracy of Sasang Constitution diagnosis, it is nessessary to collect data from the subjects who are dignosed through the evidences such as herb medicine, disease and normal symption observation, etc. Using these data, we have to evaluate correction of seperated Sasang Constitution diagnosis methods and to connect those.

• 동의생리병리학회지
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• 제23권4호
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• pp.765-771
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• 2009

The medical informatics for clustering Sasang types with collected clinical data is important for the personalized medicine, but it has not been thoroughly studied yet. The purpose of this study was to examine the usefulness of neural network data mining algorithm for traditional Korean medicine. We used Kohonen neural network, the Self-Organizing Map (SOM), for the analysis of biomedical information following data pre-processing and calculated the validity index as percentage correctly predicted and type-specific sensitivity. We can extract 12 data fields from 30 after data pre-processing with correlation analysis and latent functional relationship analysis. The profile of Myers-Briggs Type Inidcator and Bio-Impedance Analysis data which are clustered with SOM was similar to that of original measurements. The percentage correctly predicted was 56%, and sensitivity for So-Yang, Tae-Eum and So-Eum type were 56%, 48%, and 61%, respectively. This study showed that the neural network algorithm for clustering Sasang types based on clinical data is useful for the sasang type diagnostic test itself. We discussed the importance of data pre-processing and clustering algorithm for the validity of medical devices in traditional Korean medicine.

• 동의생리병리학회지
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• 제23권5호
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• pp.950-957
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• 2009

The purpose of this study was to develop generalized validity evaluation indexes for the Sasang type diagnostic test. As a generalized evaluation index for Sasang type diagnostic test, Generalized Squared Correlation (GC2), Mutual Information (I) and Mutual Information Coefficient (IC) as overall validity index, and Correlation Coefficient (C) and Mutual Information Contribution (ID) as type-specific validity index were suggested and the practicability of these indexes was assessed along with Percentage Correctly Predicted (PCP), adjusted PCP, type-specific sensitivity and type-specific specificity which was proposed previously. The usefulness of the nine validity indexes was examined using previously reported data and three mock Sasang type diagnosis results. We demonstrated here that the PCP is not adequate for the analysis of validity. We also showed that our validity index is recommendable for the comparison and improvement of Sasang type diagnosis. The generalized validity analysis of Sasang type diagnosis can provide a guideline for the development of new Sasang type diagnosis or pattern identification. The working sheet for calculating validity indexes can be acquired at http://www.sasangtypology.org/validity.

• 한국한의학연구원논문집
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• 제11권1호
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• pp.127-138
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• 2005

We have examined the phase of Bian Zheng(辨證) by individual characteristics, who underwent the Oriental Medical Physical Examination, based on the Bian Zheng questionnaire of Korea Institute of Oriental Medicine. Since the correlations in all Bian Zhengs showed meaningful results at 0.01(p-value<0.05) in terms of level of significance and all coefficients are in positive value, the correlation in these Bian Zhengs could be said to exhibit the change toward the same direction with close correlation rather than contradictory change. The mean Bian Zheng score of women was generally higher than that of men, particularly in Blood-Deficiency, Qi-Stasis, Qi-Deficiency. But there is no difference of the mean Bian Zheng score in Sasang Constitution. We performed the Linear regression analysis to see the change of Bian Zheng score by age and could presume that the older they are, the higher Bian Zheng score, but statically the result is not meaningful. By the above result, we could come to the conclusion that the Bian Zhen questionnaire is more useful to the patient than the healthy people.

• 대한한방부인과학회지
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• 제35권3호
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• pp.105-121
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• 2022

Objectives: It is a statistical analysis study to examine the results of CaPSPI (Diagnostic System for Climacteric and Postmenopausal Syndrome Pattern Identification), developed for objective defecation of climacteric and postmenopausal syndrome. Methods: Total 341 people's questionnaire responses were statistically analyzed. 275 people involved in developing CaPSPI 2018 (E) and 146 people involved in 2019-2020 study of research1,3). Results: The frequency of diagnosis for examination was the highest at liver depression, 93.8% for 320 times, the lowest at heartheat, 62.8% for 214 times. The frequency of treatment for examination was the highest at liver depression, 54.3% for 185 times, and the lowest at dual deficiency of heart-spleen, 16.7% for 57 times. The diagnosis ratio was the lowest at dual deficiency of heart-spleen, 19.72%, and the highest at liver depression, 57.81%. As a result of comparing these diagnoses with the Kupperman's index, all showed significant differences. As a result of comparing these disease elements, all showed significant differences. The correlation between diagnosis and dialectic elements was found to have similar results with the korean medical pathology, and in 7 dialectics except for heartheat, the treatment version was more severe or progressing to perjury than for examination. Conclusions: The CaPSPI shows the characteristics of korean medicine well, and it is needed to utilize the high correlative disease elements to upgrade the system.

• 동의생리병리학회지
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• 제37권6호
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• pp.172-177
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• 2023

In order to deduce the pathogenic factor(PF) diagnosis logic of underlying in pattern identification of Korean medicine, 2,072 cases of DSOM(Diagnosis System of Oriental Medicine) data from May 2005 to April 2022 were collected and analyzed by means of decision tree model(DTM). The entire data were divided into training data and validation data at a ratio of 7:3. The CHAID algorithm was used for analysis of DTM, and then validity was tested by applying the validation data. The decision rules of items and pathways determined from the diagnosis data of Qi Deficiency, Blood Deficiency, Yin Deficiency and Yang Deficiency Pathogenic Factor of DSOM were as follows. Qi Deficiency PF had 7 decision rules and used 5 questions: Q124, Q116a, Q119, Q119a, Q55. The primary indicators(PI) were 'lack of energy' and 'weary of talking'. Blood deficiency PF had 7 decision rules and used 6 questions: Q113, Q84, Q85, Q114, Q129, Q130. The PI were 'numbness in the limbs', 'dizziness when standing up', and 'frequent cramps'. Yin deficiency PF had 3 decision rules and used 2 questions: Q144 and Q56. The PI were 'subjective heat sensation from the afternoon to night' and 'heat sensation in the limbs'. Yang deficiency PF had 3 decision rules and used 3 questions: Q55, Q10, and Q102. The PI were 'sweating even with small movements' and 'lack of energy'. Conclusively, these rules and symptom information to decide the Qi·Blood·Yin·Yang Deficiency PF would be helpful for Korean medicine diagnostics.