• Journal of Biomedical Engineering Research
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• v.25 no.1
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• pp.57-64
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• 2004

The non pulsation blood pump is divided into axial flow and centrifugal style according to the direction of inlet and outlet flow. An axial flow blood pump can be made smaller than a centrifugal blood pump because centrifugal pump's rpm is fewer than axial flow pump. Hemolysis is an important factor for the development of an axial flow blood pump. It is difficult to identify the areas where hemolysis occurs. Evaluation of hemolysis both in in-vitro and in-vivo test requires a long-time and more expensive. Computational fluid dynamics(CFD) analysis enables the engineer to predict hemolysis on a computer which just can get not only amount of htmolysis but also location of hemolysis. It takes shorter time and less expensive than in-vitro test. The purpose of this study is to git Computational fluid dynamics in axial flow pump and to verify the accuracy of prediction by the possibility of design comparing CFD results with in-vitro experimental results. Also, wish to figure out the correction method that can bring improvement in shape of axial flow blood pump using CFD analysis.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.42 no.6
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• pp.843-852
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• 2022

Despite continuous safety management, the death rate of construction workers is not decreasing every year. Accordingly, various studies are in progress to prevent construction site accidents. In this paper, we developed an AI-based priority inspection target selection model that preferentially selects sites are expected to cause construction accidents among construction sites with construction costs of less than 5 billion won (KRW). In particular, Random Forest (90.48 % of accident prediction AUC-ROC) showed the best performance among applied AI algorithms (Classification analysis). The main factors causing construction accidents were construction costs, total number of construction days and the number of construction performance evaluations. In this study an ROI (return of investment) of about 917.7 % can be predicted over 8 years as a result of better efficiency of manual inspections human resource and a preemptive response to construction accidents.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.12
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• pp.468-474
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• 2019

Korea had the highest accident rate among OECD countries in 2018, with 8.4 per 100,000 population, ranking 4th among 35 countries. In addition, the accident rate of traffic with children and the elderly was also high. This study reviewed the relevant literature and analyzed the traffic-accident analysis system. Customized traffic safety facilities were developed. In addition, by measuring the visibility of the traffic safety facilities by installing a test bed, this study measured the forward driving frequency and vehicle driving speed while driving. As a result of applying the "pedestrian pedestrian model" collision test model, the possibility of serious injury after installing the facility was reduced greatly to 4.6%. In this study, the visibility of traffic safety facilities and the effect of reducing the traffic speed were verified through test beds. Recognizing traffic safety facilities will reduce traffic accidents.

• Journal of the Korea Society of Computer and Information
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• v.28 no.5
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• pp.17-28
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• 2023

Potholes that occur on paved roads can have fatal consequences for vehicles traveling at high speeds and may even lead to fatalities. While manual detection of potholes using human labor is commonly used to prevent pothole-related accidents, it is economically and temporally inefficient due to the exposure of workers on the road and the difficulty in predicting potholes in certain categories. Therefore, completely preventing potholes is nearly impossible, and even preventing their formation is limited due to the influence of ground conditions closely related to road environments. Additionally, labeling work guided by experts is required for dataset construction. Thus, in this paper, we utilized the Mean Teacher technique, one of the semi-supervised learning-based knowledge distillation methods, to achieve robust performance in pothole image classification even with limited labeled data. We demonstrated this using performance metrics and GradCAM, showing that when using semi-supervised learning, 15 pre-trained CNN models achieved an average accuracy of 90.41%, with a minimum of 2% and a maximum of 9% performance difference compared to supervised learning.

• Tuberculosis and Respiratory Diseases
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• v.53 no.3
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• pp.309-318
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• 2002

Background : Usual interstitial pneumonia (UIP) is a fatal progressive fibrotic disorder of the lung with unknown etiology and characterized by a poor response to conventional immunosuppressive therapy. The histologic hallmark of UIP is parchy distribution of subpleural fibrosis and fibroblastic foci(FBF) with interposed normal appearing lung. Because FBF is a collection of actively proliferating myofibroblasts, it can be a marker of activity and prognosis of UIP. However, there were contradictory reports about the correlation between the degree of FBF and survival. Therefore we performed this study to investigate the value of FBF as prognostic marker of UIP. Methods : This was a retrospective study on the 46 patients(M:F=33:13, mean age:$59{\pm}12$ years) with UIP diagnosed by the surgical lung biopsy at the Asan Medical Center, Seoul, Korea between 1990 and 2000 and had follow-up of more than a year. All the biopsy specimens were reevaluated and diagnosed as UIP according to the ATS/ERS classification. Semiquantitative grading of FBF(absent, 0; mild 1; moderate 2; marked 3) by the experienced pathologists who did not know the clinical findings were compared to the clinical data and the follow up course. Results : Thirteen patients(28.2%) died of UIP progression during the study period. The median survival time of all the subjects was 26 months after the biopsy. At the univariate analysis, FVC, $D_Lco$, smoking history and the grade of FBF were significantly related to the survial. The survival was longer in subjects with lesser degrees of FBF, higher DLco, higher FVC and history of smoking. However the multivariate analysis with Cox regression test showed the extent of FBF was the only independent prognostic marker of UIP. Conclusion : These data suggested that the extent of FBF on the surgical lung biopsy can be used as a prognostic marker of UIP.

• Journal of Life Science
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• v.26 no.6
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• pp.705-710
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• 2016

Colorectal cancer (CRC) is the third most common cancer and a leading cause of cancer-related death worldwide. Although several diagnostic and therapeutic tools have been available, CRC remains difficult to complete cure because of insufficient understanding of the molecular mechanisms underlying this disease progression. MicroRNAs (miRNAs) are small non-coding RNA molecules that strongly regulate gene expression via transcriptional and translational control mechanisms. Many crucial cellular pathways are frequently disrupted in cancer development process due to dysregulation of several miRNAs. Mir-31 functions as an oncogene that modulate expression of multiple cancer related genes. Thus, we aimed to demonstrate clinical relevance of miR-31 in human CRC. Quantitative RT-PCR analysis of miR-31 expression was performed in 175 CRC tissues and 16 normal colonic mucosa (NM). Next, we investigated clinical significances of miR-31 expression in various clinicopathologic features in CRC patients cohort. Mir-31 was significantly up-regulated in CRC tissues compared to NM. In CRC tissues, miR-31 expression level was significantly elevated in a stage-dependent manner, which was associated with poor survival in patients with CRC. High miR-31 levels in CRC tissues significantly correlated with poor prognosis (hazard ratio [HR]=2.4) as well as distant metastasis (odds ratio [OR]=2.3). In conclusion, we identified clinical significance of miR-31 expression in CRC. High miR-31 expression may be clinically able to use as a biomarker for CRC prognosis and predicting metastasis.

• Journal of Chest Surgery
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• v.40 no.6 s.275
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• pp.420-427
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• 2007

Background: Postpneumonectomy empyema (PPE) due to bronchopleural fistula (BPF) can be a surgical challenge for surgeons. We analyzed the follow-up outcomes after performing omentopexy and thoracoplasty for the treatment of PPE with BPF after pneumonectomy. Material and Mehod: Between December 1991 and January 2006, 9 patients underwent BPF closure using an omental pedicled flap for the treatment of PPE with BPF after pneumonectomy. There were 7 males and 2 females (mean age: $45.9{\pm}9$ years). The patients were followed up for a mean of 58 months (median: 28 months, range: $6{\sim}169$). When we performed omentopexy, the surgical procedures for empyema were thoracoplasy for 8 patients and the Clagett procedure for 1 patient. Thoracoplasty was performed for the latter patient due to recurrence of empyema, Result: For the 8 patients who were treated by omentopexy and thoracoplasty, there was 1 operation-related death due to sepsis. During follow up, 1 patient, who was treated by omentopexy and a Clagett procedure, died of acute hepatitis 40 months postoperatively. The early mortality was 11.1% (8/9). Of the 8 patients, including the 1 late death patient, successful closure of the BPF were achieved in all patients (8/9) and the empyema was cured in 7 patients (7/8). Conclusion: The BPF closure using an omental pedicled flap was an effective method for treating PPE with BPF due to 75-destroyed lung, and thoracoplasty with simultaneous omentopexy was effective and safe for removing dead space if the patient was young and in a good general condition.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.12
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• pp.8728-8737
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• 2015

The purpose of this study compared the clinical features of suicidal attempters who visit in the past and present of an emergency medical center, used as a basic data for clinical severity and suicide prevention research of future patients. The author conducted a retrospective analysis of the changed characteristics of suicidal attempters who visit an emergency medical center of Wonkwang University Hospital between from January $1^{st}$, 1998 to December $31^{th}$, 1998 and from August $1^{st}$, 2013 to July $31^{th}$, 2015. Factors related to increased occurrence was changed from male(1.1:1) in 1998 to female(1.3:1) in 2013-2015, from age of $2^{nd}$, $3^{rd}$, and above $6^{th}$ decade in 1998 to $3^{rd}-5^{th}$ decade in 2013-2015. Poisoning was the most common method of suicidal attempt(90.8%;1998, 72.7%;2013-2015), Mortality rate was changed from 16.9%(male 23.1%, female 10.0%) in 1998 to 13.8%(male 18.1%, female 10.5%) in 2013-2015. Among the suicidal attempters(total=516), 37 patients has recurred. But consultant of neuropsychiatric department was 48.3%, All suicidal attempters in future were necessarily neuropsychiatric consultant and continuously follow-up because all patients had recurrent suicide attempt, psychologic disorder, suicide rates are higher than in the general population.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.476-476
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• 2011

베트남은 자연재해로 인해 매년 평균 750명 이상의 사망자가 발생하고 있으며, 경제적인 피해 또한 한해 GDP의 1.5%에 달하고 있다. 저먼워치(Germanwatch)의 2010년 세계기후위험지수(Global Climate Risk Index, GCRI)의 전 지구적 기후재난에 관한 국가별 순위 조사에서 베트남은 4위에 기록되었다. 베트남의 자연재해는 상당 비중이 풍수해에 집중 되어 전체 재해의 86%를 차지하고 있고, 이는 대부분 해안 지대와 강 유역의 홍수 및 범람에서 비롯된 것이다. 베트남 전체인구의 약 70%가 상습적 홍수와 범람 발생 지역인 해안가에 거주하고 있어 재난에 예방 및 복구 관리에 대한 국가 차원의 방안이 시급한 실정이다. 본 연구에서는 과거 30년간의 풍수해 관련 재해에 대한 기록상 추이를 통해 공간적으로 재난에 취약한 지역적 분포를 살펴보고, 그 지역의 지리적 특성을 분석하여 재해에 관한 종합적 고찰을 하였다. 벨기에 루뱅대학 부설 재난역학연구센터(Centre for Research on the Epidemiology of Disasters, CRED)의 EM-DAT를 이용하여 과거 기록상의 개괄적인 재해양상에 관한 추이를 살펴본 결과 대부분의 재난은 풍수해에 집중이 되어 있음을 분석하였고, 베트남 풍수해조정기관인 홍수및폭풍조정중앙위원회(Central Committee for Flood and Storm Control, CCFSC)의 최근 30년간 풍수해에 관련된 통계 자료를 정리하여 상습적 재난 피해지역을 지도상에 표시하였다. 이 때 지구지도제작운영위원회(International Steering Committee for Global Mapping, ISCGM)의 D_WGS_1984 Datum을 바탕으로 한 베트남 shape file을 이용하여 풍수해에 따른 인명피해, 경제적 손실, 발생횟수 등에 관한 사항을 일반화 시켜 재난 취약지역을 지리적으로 분석하였다. Thanh hoa, Quang nam, Binh Dinn, Camau성이 풍수해와 관련된 재난에 취약하게 노출되어 있음을 도출하였다. 재난에 상대적으로 취약한 이들 지역에 대한 현재의 재난 관리는 어떻게 이루어지고 있는지에 관해 현재의 풍수해관리 사업단의 조직적 구조와 그 기능 및 역할을 살펴보고, 국제적 원조 사례를 분석하여 상습적으로 재난의 위험 지역에 대한 지속적인 관리와 복구를 어떻게 이루어 나갈 것인지에 대한 방안 및 제언에 관하여 논의하고자 한다. 베트남의 재난 관리에 관한 지리적인 종합 분석은 기존 양상의 재해에 대한 방안을 구축하는 데 대한 제언뿐만 아니라 기후변화와 관련된 재난을 예측하고 관리 방안을 설정하는 데 기초 자료를 제공할 수 있을 것이다.

• Nuclear industry
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• v.37 no.9
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• pp.58-90
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• 2017

'공포의 값비싼 대가(The High Cost of Fear)'는 공개된 자료 중 동료 평가를 마친 최신의 자료와 간단한 계산 방법을 통해 한국의 탈원전 정책이 가져올 경제적, 환경적 영향을 분석한 보고서이다. 우리는 탈원전 정책이 다음과 같은 영향을 미칠 것으로 예측한다. ${\cdot}$천연가스 구매에만 최소 매년 100억 달러의 비용이 들 것이다. 이는 한국 평균임금인 연소득 29,125달러를 받는 일자리 343,000개에 해당하는 금액이다. ${\cdot}$비용의 대부분은 연료 수입에 사용될 것이며, 한국의 무역 수지가 악화될 것이다. ${\cdot}$한국의 부족한 재생에너지 자원을 고려할 때, 상당한 양의 화석 연료를 추가로 사용하게 될 것이다. ${\cdot}$LNG 발전소가 석탄 발전소를 대체하지 못하고 원자력발전소를 대체하면서 대기 오염으로 인한 조기 사망자 수가 증가할 것이다. ${\cdot}$한국의 전도유망한 원전 수출 산업이 아예 붕괴되거나 큰 타격을 입을 것이다. ${\cdot}$평균적 미국 자동차의 연간 주행거리를 기준으로 150만대에서 270만대의 미국 자동차가 배출하는 배기가스의 양만큼 연간 탄소 배출이 증가할 것이고, 한국은 파리기후협정에서 약속한 탄소 배출 감축 목표를 달성할 수 없게 된다. 본 보고서는 현재 계획된 탈원전 정책의 역사적 사회적 배경을 분석하여 다음과 같은 결론을 도출하였다. ${\cdot}$'그린피스(Greenpeace)', '지구의 친구들(Friends for the Earth)' 등 막대한 자금 지원을 받는 해외 환경단체들은 탈원전 거짓 정보의 근원이며, 이들은 저렴하고 풍부한 에너지라는 개념을 반대한다. ${\cdot}$후쿠시마 원전 사고와 그 여파의 주된 원인은 일본 원자력산업계의 오만과 원자력에 대한 과장된 집단 공포이다. ${\cdot}$반핵 진영의 논리에는 산업계와 정부에 대한 불신과 원자력, 방사선에 대한 몰이해가 반영되어 있다. ${\cdot}$반핵 진영은 후쿠시마 사고를 2014년 한수원 납품 비리 사태의 심각성을 과장하는 데 사용하고 있다. 2014년의 비리 사태는 한국 원자력 규제기관의 독립성을 증명했으며, 2016년의 경주 지진은 2011년 후쿠시마에서 쓰나미와 노심 용융을 초래한 동일본 대지진의 1/350,000의 크기밖에 되지 않는다. 본 보고서는 한국과 타국가의 반핵 운동이 주는 교훈을 다음과 같이 정리하였다. ${\cdot}$어떠한 국가도 에너지 자원 최빈국인 프랑스나 한국 같은 국가조차도 탈원전 '전쟁'에서 자유롭지 않으며, 이는 전 세계적으로 원자력산업이 쇠퇴하는 원인이다. ${\cdot}$원자력산업계, 정부, IAEA 등은 한국과 세계 여러 국가에서- 문화적, 제도적, 재정적 원인으로 원자력산업의 보호와 확대라는 목표를 달성할 수 없다. ${\cdot}$원자력산업을 구하기 위해서는 새로운 비전과 새로운 제도, 그리고 새로운 리더십이 필요하다. ${\cdot}$원자력의 근원적이고 혁신적인 비전 원자력 인본주의(atomic humanism)에 대한 재조명이 필요하다. ${\cdot}$원자력을 지키고 대중과 소통하기 위해 과학 연구단체, 대학교, 사단법인, NGO 등의 새로운 기관들을 후원해야 한다. ${\cdot}$공포를 조장하는 반원전 세력에 맞서 공포를 극복해야 하고, 대중의 공포를 극복해왔던 다른 기술들의 사례에서 교훈을 얻어야 한다.