• Korean Journal of Microbiology
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• v.51 no.2
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• pp.177-180
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• 2015

For prevention of atrophic rhinitis of swine by Bordetella bronchiseptica and fowl typhoid by Salmonella gallinarum, bacterial strains showing antimicrobial activity against those pathogenic bacteria were isolated from various samples collected at animal farms. Among 372 bacterial isolates strain TK3 showed the highest antibacterial activity against both pathogens, and was identified as Bacillus amyloliquefaciens by 16S rRNA gene sequence analysis. B. amyloliquefaciens TK3 could inhibit growth of both pathogens by secretion of antibacterial compounds such as siderophore, rhamnolipid and antimicrobial peptide. Production radius of siderophore on Chrome azurol S agar plate by strain TK3 was 0.53 cm after 14 days of incubation, and concentration of siderophore in King's B medium was 1.06 mmol/ml. It also secreted 82.4 mg/L of rhamnolipid, and antimicrobial peptide that completely inhibited growth of both pathogens at concentration of $30{\mu}l/ml$ in LB medium.

• Journal of Industrial Convergence
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• v.18 no.5
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• pp.70-76
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• 2020

The purpose of this study was to determine the dietary behavior of adolescents and to determine the association with allergic diseases according to dietary behavior. The data were obtained from the 15th Korea Youth Risk Behavior Survey 2019. Complex-sample descriptive statistics and the chi-square test were used for data analysis in SPSS. Adolescents diagnosed with asthma had a relationship with frequency of breakfast, fruit, soda, energy drink, sweet drink, fast food, vegetable and convenience store eating experience. Adolescents diagnosed with allergic rhinitis were associated with frequency of breakfast, fruit, soda, sweet drinks, vegetables, and milk. Adolescents diagnosed with atopic dermatitis were associated with soda, vegetables, milk, and convenience store eating experiences. Therefore, in the case of adolescents with allergic diseases, it is necessary to educate them on correct dietary behavior so that they can have correct habits.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.1 s.32
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• pp.218-227
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• 2007

Objective : The purpose of this study is to investigate outpatients of hypersensitive rhinitis including allergic rhinitis who had visited to Hospital of Oriental Medicine. Method : We analyzed statistics study in 580 patients, who had visited to the Dept. of dermatology, ophthalmology & otorhinolayngology Hospital of Oriental Medicine Dongeui University from March, 1998 to December, 2006. Results : The results were as follows. 1. There is more male(53.28%) than femal(46.72%). The age distributions of patients showed highest in 20-29 years, followed by 10-19 years, 30-39 years in order. 2. The yearly distributions of patients showed highest in 2004, followed by 2001, 2005 in order. The seasonal distributions of patients showed highest in fall, followed by winter, summer, spring in order. The monthly distributions of patients showed highest in September, followed by August, October in order. 3. The distributions of number of times in treatment showed highest in 1-5 times. The distributions of duration of treatment showed highest in 1 week. In the treatment method, a major portion of treatment methods was acupuncture, followed by herbal medicine treatment, aroma therapy in order. 4. The Frequency of use of Prescriptions showed highest in Bojungikgi-Tanggami. The Frequency of use of Extract showed highest in Sochungryong-Tang. 5. The distribution of past history showed highest in Atopic dermatitis. The distribution of Rhinologic Complication showed highest in Paranasal sinusitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.17 no.2
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• pp.72-80
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• 2004

Background and Objectives: Recently the incidence of allergic rhinitis has increased but treatment in most cases has only dealt with the symptoms. Medicine has been developed that shows fewer side effects. However, some side effects and the psychological stress over taking medicine have remained. There have been no studies so far performed on the effect of Lizhongtang plus Baidusan Extract. This study aimed to find out the therapeutic effects of its exclusive use in rats with Allergic Rhinitis. Materials and Methods : Thirty Sprague-Dawley rats were divided into three groups: the control group, the cetirizine HCI group and the sample group. To induce allergic rhinitis in the control group, the cetirizine HCI group and the sample group, rats were sensitized intraperitoneally with 0.1$\%$ ovalumin solution 3 times at an interval of I week. Then intranasal sensitization was performed by diffusing 0.1$\%$ ovalumin solution 3 times at an interval of 2 days. After that time, rats of the cetirizine HCI group were orally administered with cetirizine HCI. Rats of the sample group were treated with Lizhongtang plus Baidusan Ex. for 28 days. We observed changes in nasal mucosa and submucosa. Also we found changes in the segment of neutrophil and lympocyte in Leukocyte. We used the statistical methods of ANOVA test(p 〈0.05). Results: The loss of the cilium and the secretion of mucus in the treated group was rare when compared to control group. Effects of Lizhongtang plus Baidusan Ex. on the liver function were also studied in rats. Treatment of Lizhongtang plus Baidusan Ex. did not affect AST and ALT. The segment of neutrophil was significantly increased in the treated group when compared with the control group and the cetirizine HCI group(p 〈0.05). The segment of lympocyte was significantly decreased in the treated group when compared with the control group and the cetirizine HCI group(p 〈0.05). Conclusion: This study shows that Lizhongtang plus Baidusan Ex. decreases the inflammatory response in rats with Allergic Rhinitis.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.101-109
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• 2014

Objective : The purpose of this study is to summarize the differential diagnosis between allergic and nonallergic rhinitis and suggest management. Methods : We reviewed the current update of medical history and physical examination for allergic and nonallergic rhinitis. Then we analyzed clinical characteristics according to onset age, gender incidence and state of nasal symptoms, etc. Results : 1. Patients with nonallergic rhinitis tend to develop symptoms at a later age(>35 years of age), and there is a female-to-male incidence ratio for nonallergic rhinitis of 2:1 to 3:1. 2. Patients with nonallergic rhinitis report nasal congestion, nasal rhinorrhea and more often report postnasal drip rather than sneezing and itching, which are predominant symptoms of allergic rhinitis. And the nasal mucosa in nonallergic rhinitis usually looks normal. 3. Patients with nonallergic rhinitis have few complaints of concomitant symptoms of allergic symptoms and the absence of other atopic diseases in the patient or in the family supports the diagnosis of nonallergic rhinitis. 4. Common triggers of nonallergic rhinitis are nonspecific irritant exposures and many patients with nonallergic rhinitis find that antihistamines have no benefit. Conclusions : The differential diagnosis between allergic and nonallergic rhinitis is clinical and relies on a detailed medical history and physical examination.

• Journal of the Korea Convergence Society
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• v.10 no.6
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• pp.347-353
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• 2019

This study was a descriptive research to investigate the difference of obesity, smoking, drinking affected allergy disease in Korean adolescents using the raw data of $6^{th}$ Korea National Health and Nutrition Survey(2015). Study data on 535 Korean adolescents classified 12 to 18 years and Rao-Scott Chi-square test and logistic regression were used for analysis. The results of the study showed that the prevalence of asthma, atopic dermatitis, allergic rhinitis were 5.4%, 15.5%, 22.8% and not shown differences according obesity, smoking, drinking. But, the risk factor of asthma was related obesity, atopic dermatitis was related smoking. Based of this study's findings, It is necessary to develop the Heath Promotion Intervention Program according of obesity, drinking, smoking for the quality of life in adolescents diagnosed Allergy disease.

• Journal of Korean society of Dental Hygiene
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• v.23 no.6
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• pp.475-483
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• 2023

Objectives: This study aimed to determine whether adolescents with allergic rhinitis are at an increased risk of stomatitis and to ascertain possible sex-specific differences. Methods: The data for this cross-sectional study was obtained from the 18th Korea Youth Risk Behavior Web-based Survey (2022). Of the 56,213 students surveyed, 51,850 (boys 26,397 and girls 25,453) were included in the final analyses. Multivariate logistic regression was performed to identify the impact of allergic rhinitis on the risk of stomatitis among Korean adolescents. Results: In Model II, which was adjusted for allergic disease, boys with allergic rhinitis had a 1.53-fold (adjusted odds ratio [aOR]=1.53, 95% confidence interval [CI]=1.40-1.67), and girls had a 1.35-fold (aOR=1.35, CI=1.25-1.46) elevated risk of stomatitis than in those without. In Model III, after adjusting for all covariates, boys with allergic rhinitis had a 1.48-fold (aOR=1.48, CI=1.36-1.62) elevated risk of stomatitis than in those without, and girls had a 1.32-fold (aOR=1.32, CI=1.22-1.43) elevated risk, which remained statistically significant after adjusting for covariates. Therefore, allergic rhinitis in adolescents exerts a detrimental effect on the risk of experiencing stomatitis symptoms; the risk was higher in boys than in girls. Conclusions: These findings suggest that oral health care attention and intervention are needed for adolescents with allergic rhinitis.

• Pediatric Infection and Vaccine
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• v.17 no.2
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• pp.91-100
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• 2010

Purpose : Recurrent otitis media (ROM) is usually defined as ${\geq}$3 distinct and well-documented episodes within 6 months or ${\geq}$4 episodes within 12 months. ROM is sufficiently important to warrant consideration of chemoprophylaxis, tympanostomy tube placement. There also is evidence that children with ROM are at risk for both hearing loss and speech delay. However, studies of ROM have been notably insufficient. In addition, even though environmental, racial, and sociocultural differences can affect risk factors, few studies have been conducted with regard to recurrent otitis media in Korea. Methods : This study was conducted from July 2009 to January 2010 with infants and children who were younger than 60 months old, who visited the out-patient clinics at Han-Il General Hospital and Kyunghee University Hospital. Data were collected by interview using a pre-formed sheet. Among a total of 892 infants and children, 457 were excluded, and the remaining 435 were allocated to 104 with ROM and 331 as a control group. Results : Attendance at daycare centers (P<0.001, OR=2.85), allergic rhinitis (P=0.026, OR=2.32), past history of bronchiolitis (P=0.003, OR=2.33), and low socioeconomic status (P=0.005, OR=2.00) were found to have a close significant correlation with ROM. Risk factors such as sex, having a sibling, breast-feeding, use of pacifiers, atopy, pneumococcal vaccination, influenza vaccination, smoking of parents, and indoor smoking are not relevant. Conclusion : Attendance at daycare centers, allergic rhinitis, past history of bronchiolitis, and low socioeconomic status have been identified as risk factors for ROM.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.66 no.1
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• pp.72-79
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• 2021

The increasing use of deicing salts has caused various environmental problems, including crop damage along the motorway where deicing salts are sprayed during winter. Deicing salts used on roads have been reported to negatively affect crops, but little information is known about their impact on crops. A seedling emergence assay was conducted to evaluate the effects of deicing salts on crops using oilseed rape (Brassica napus) as a model plant. We tested five chloride deicing salts consisting of NaCl, CaCl2, or MgCl2 and 1 non-chloride deicing salt (SM-3) at a range of concentrations (25, 50, 100, 200, and 400 mM), and untreated control. Regardless of deicing salts, they significantly delayed and reduced seedling emergence of oilseed rape with increasing salt concentration. Non-linear regression analysis of seedling emergence with a range of salt concentrations by fitting to the log-logistic model revealed that the chloride deicing salts reduced seedling emergence more than the non-chloride deicing salt SM-3. The GR50 value, the concentration causing 50% seedling emergence, of SM-3 was 47.1 mM, while those of the chloride deicing salts ranged from 30.7 mM (PC-10) to 37.5 mM (ES-1), showing approximately 10 mM difference between non-chloride and chloride deicing salts. Our findings suggest that seedling emergence assay is a useful tool to estimate the potential damage caused by deicing salts on crops.

• Korean Journal of Oriental Medicine
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• v.1 no.1
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• pp.335-345
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• 1995

The clinical study was done as apreliminary to treat Rhinitis with orinetal medicine. We analysed 73 patients with sneezing, nasal discharge and nasal obstruction, who had visited Kept. of Internal Medicine. Hospital of Oriental Medicine, Dongui University from Jan, 1, 1993 to Dec, 31, 1993. The result swere obtained as follows. 1. In the sex ratio, man was higher than woman as 2.31:1 and in age distribution, below 10s was the top as 30.14% 2. In duration of hestory, over one year was the top as 64.38% 3. The most complained symptoms were nasal discharge and nasal obstruction as 94.52% 4. In the frequency of treatments, the cooler season was more than the warmer season 5. In the treatments of Medi-acupunctrer, most of acupuncture therapy was oden less than 5 times and Seonotanggami was most rsed in presciptions. 6. In the case of applying to Seonotanggami, nasal discharge was the most relieved symptom.