• Title/Summary/Keyword: 분별도

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Development of An Improved Acetone-Water Fractional Precipitation Process for Purification of Paclitaxel from Taxus chinensis and Its Kinetic and Thermodynamic Analysis (Taxus chinensis로부터 파클리탁셀 정제를 위한 개선된 아세톤-물 분별침전 공정 개발 및 그 동역학 및 열역학적 해석)

  • Kang, Hoe-Jong;Kim, Jin-Hyun
    • Korean Chemical Engineering Research
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    • v.59 no.3
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    • pp.379-392
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    • 2021
  • In this study, an improved acetone-water fractional precipitation process for paclitaxel using ultrasonic cavitation bubbles and gas bubbles was developed. Compared to the conventional method, the time required for precipitation has been reduced by 20~25 times. In addition, the particle size of paclitaxel decreased by 3.5~5.5 times and the diffusion coefficient of paclitaxel increased by 3.5~6.7 times. In the case of precipitation using ultrasonic cavitation bubbles, as the ultrasonic power increased and the temperature decreased, the precipitation rate constant increased. In the case of precipitation using gas bubbles, as the gas flow rate increased and the temperature decreased, the precipitation rate constant increased. Thermodynamic parameters revealed the exothermic, irreversible, and nonspontaneous nature of the improved fractional precipitation.

Petrological Study on the Cretaceous Volcanic Rocks in the southwest Ryeongnam Massif: (1) the Mt. Moonyu volcanic mass, Seungju-gun (영남육괴 남서부에 분포하는 백악기 화산암류에 대한 암석학적 연구: (1) 승주군 문유산 화산암복합체)

  • Kim, Young-La;Koh, Jeong-Seon;Lee, Jeong-Hyun;Yun, Sung-Hyo
    • The Journal of the Petrological Society of Korea
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    • v.17 no.2
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    • pp.57-82
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    • 2008
  • The volcanic sequence of the late Cretaceous Moonyu volcanic mass which distributed in the southwestern part of Ryeongnam massif, can be divided into felsic pyroclastic rocks, andesite and andesitic pyroclastic rocks, rhyolite in ascending order. The earliest volcanic activity might commence with intermittent eruptions of felsic magma during deposition of volcaniclastic sediments. Explosive eruptions of felsic pyroclastic rocks began with ash-falls, to progressed through pumice-falls and transmitted with dacitic to rhyolitic ash-flows. Subsequent andesite and andesitic pyroclastic rocks were erupted and finally rhyolite was intruded as lava domes along the fractures near the center of volcanic mass. Petrochemical data show that these rocks are calc-alkaline series and have close petrotectonic affinities with subduction-related continental margin arc volcanic province. Major element compositions range from medium-K to high-K. Petrochemical variation within the volcanic sequence can be largely accounted for tractional crystallization processes with subordinate mixing. The most mafic rocks are basaltic andesite, but low MgO and Ni contents indicate they are fractionated by fractional crystallization from earlier primary mafic magma, which derived from less than 20% partial melting of ultramafic rocks in upper mantle wedge. Based on the stratigraphy, the early volcanic rocks are zoned from lower felsic to upper andesitic in composition. The compositional zonation of magma chamber from upper felsic to lower andesitic, is interpreted to have resulted from fractionation within the chamber and replenishment by an influx of new mafic magma from depth. Replenishment and mixing is based on observations of disequilibrium phenocrysts in volcanic rocks. REE patterns show slight enrichment of LREE with differentiation from andesite to rhyolite. Rhyolite in the final stage can be derived from calc-alkaline andesite magma by fractional crystallization, but it might have underwent crustal contamination during the fractional crystallization.

The Structure of the Theory of Three Natures from the Hermeneutic Perspective of "the Three Turns of the Dharma Cakra" ('3전법륜설'의 해석학적 지평으로 본 삼성설의 구조)

  • Kim, Jae-gweon
    • Journal of Korean Philosophical Society
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    • v.117
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    • pp.35-55
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    • 2011
  • This article purports to clarify the doctrinal characteristics of the $Yog{\bar{a}}c{\bar{a}}ra$ school's hermeneutic interpretations of the "theory of the three turns of the Dharma Cakra" in the Saṃdbinirmocana-sūtra through early Indian $Yog{\bar{a}}c{\bar{a}}ra$ treatises such as the $Yog{\bar{a}}c{\bar{a}}rabb{\bar{u}}mi-vy{\bar{a}}kby{\bar{a}}$ and the. $Vy{\bar{a}}khy{\bar{a}}yukti$. It will probe how these interpretations apply co the theory of two truths or that of three natures($trisvabh{\bar{a}}va$) among the main doctrines of the $Yog{\bar{a}}c{\bar{a}}ra$ school. Especially, the peculiar characteristic of the "theory of the three turns of the Dharma Cakra" is such chat the thought of ${\acute{s}}{\bar{u}}nyat{\bar{a}}$ in the lineage of $Praj{\bar{n}}{\bar{a}}p{\bar{a}}ramita-s{\bar{u}}tras$ is regarded as incomplete, as the early school of Madhyamaka represented by $N{\bar{a}}g{\bar{a}}rjuna$ is conceived of as belonging to the second period of turn. Speaking of the further details of the "theory of the three turns of the Dharma Cakra", the $Yog{\bar{a}}c{\bar{a}}ra$ school subdivides the realm of saṃvṛti satya in $N{\bar{a}}g{\bar{a}}rjuna^{\prime}s$ theory of two truths; that is, it divides the saṃvṛti into merely linguistic existence and actual existence, and the thus-created structure of the theory of three natures on the basis of ocher-dependent nature(paratantra-$svabh{\bar{a}}va$) makes it possible to establish the doctrinal system of the thought of ${\acute{s}}{\bar{u}}nyat{\bar{a}}$ that is not subject to "nihilism or ${\acute{s}}{\bar{u}}nyat{\bar{a}}$ attached to evil." In effect, the above hermeneutic interpretation of the "theory of the three turns of the Dharma Cakra" is inherited into the structure of the $abh{\bar{u}}taparikalpa$ in the $Madhy{\bar{a}}nta-vibh{\bar{a}}ga$ so that, as seen in the commentary of Sthiramati, it is ascertained to apply to later doctrines through its secure establishment. To summarize its characteristics succinctly, firstly the $abh{\bar{u}}taparikalpa$ newly established as a saṃvṛti-satya is set up as the other-dependent nature, which is seen to have been set up particularly in order to sublate both the $Sarv{\bar{a}}stiv{\bar{a}}da^{\prime}s$ realist "view of being" and the Madhyamaka's "view of ${\acute{s}}{\bar{u}}nyat{\bar{a}}$" that impairs the ocher-dependent nature as a samvṛti-satya. In other words, according to the five kinds of views suggested in Sthiramati's commentary, the three natures are seen to be presented as the fundamental truth in order to unify all the doctrinal systems available ever since the beginning of Buddhism. Then, the theory of three natures is established principally on the basis of the $abh{\bar{u}}taparikalpa$, while the two truths of the $Yog{\bar{a}}c{\bar{a}}ra$ school are clearly ascertained to have been embedded in the structure of the $abh{\bar{u}}taparikalpa$. In fact, this might be understood to reflect the unique ontological view of reality or truth in the $Yog{\bar{a}}c{\bar{a}}ra$ School.

Studies on Milk Protein of Korean Cattle I. Fractionation of Milk Protein on DEAE-Cellulose (한우유(韓牛乳)의 단백질(蛋白質)에 관(關)한 연구(硏究) 제(第)1보(報) DEAE-Cellulose에 의(依)한 한우유단백질(韓牛乳蛋白質)의 분별(分別))

  • Kim, Y.K.;Chang, J.I.
    • Korean Journal of Food Science and Technology
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    • v.6 no.2
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    • pp.75-78
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    • 1974
  • An experiment has been carried out in order to analyze the main components of Korean Cattles' milk, and fractionate the milk protein by DEAE-cellulose column. The results obtained were summarized as follow. 1) The average values of specific gravity, pH and acidity of Korean Cattles milk which were negative in alcohol test were 1,036, 6.4 and 0.21, respectively. 2) The average values of total solids, solids-not-fat, protein, lactose and ash contents of Korean Cattles milk were 11.61%, 9.53%, 2.08%, 3.99%, 4.76% and 0.86%, respectively. 3) Distribution of casein, whey protein, N.P.N., protein precipitated in 12% TCA, lactoglobulin and lactalbumin contents of the milk were 3.07%, 1.13%, 0.10%, 4.06%, 0.34% and 0.66%, respectively. 4) Acid casein obtained from Korean Cattles milk was fractionated into four fractions on DEAE-cellulose column with 0.005M tris-citrate buffer containing 6M urea, pH 8.6, and the ratio of the fraction I, II, III and IV was 3.24%, 52.67%, 26.22% and 17.87%, respectively. 5) Whey protein obtained from Korean Cattles milk was also fractionated into four fractions on DEAE-cellulose column with 0.04M phosphate buffer, pH 5.8, and the ratio of the fraction I, II, III and IV was 41.74%, 10.17%, 1.50% and 46.59%, respectively.

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Geochemical Characteristics of the Quaternary Jungok Basalt in Choogaryong Rift Valley, Mid-Korean Peninsula (추가령 열곡대에 분포하는 전곡현무암의 지화학적 특성)

  • Wee, Soo-Meen
    • Economic and Environmental Geology
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    • v.29 no.2
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    • pp.171-182
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    • 1996
  • Quaternary Jungok basalts are distributed along the old Hantan river in Mid-Korean Peninsula. They were flowed out from Mt. Ori and Upland (680 m), and they formed narrow and long basalt plateau showing the layers of 10 to 20 meters in thickness and about 95 km in length. Fifty seven samples were collected from the study area, and sixteen rock samples were selected and analysed for major and trace elements. The analyzed samples have alkalic composition and show a relatively restricted variation in major element chemistry (except MgO), as comparing to the that of trace element. Based on major element chemistry, a quantitative modelling of fractional crystallization by multiple linear regression method suggests that the chemical evolution of the evolved rocks can be generated by fractionation of olivine, plagioc1ase, clinopyroxene, and magnetite in proportion of 56 : 25 : 17 : 2, respectively. The calculated trace element abundances by mineral proportions estimated from major element modelling, however, underestimate the incompatible element concentrations in the evolved rocks. According to the incompatible element abundances, simple fractional crystallization process has difficulty to explain the chemical variation of the evolved rocks. It seems that the other processes, which enrichment of incompatible elements can occure without concomitant changes in major element compositions, are needed in order to explain the chemical variation of the Jungok basalts. Thus, the major elements and compatible trace elements variations of the Jungok basalts are due to fractional crystallization, but the incompatible elements variation is due to fractional crystallization superimposed on already varying concentrations caused by slightly different degrees of melting of the same source, and/or due to periodic replenishment, tapping and fractionation(RTF) processes.

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A Comparative Analysis on Generated Construction Waste Quantities in a Case Study for Deconstruction of an Apartment (공동주택의 분별해체 시험시공을 통한 건설폐기물 발생량 비교 분석)

  • Kim, Hyojin;Kang, Leenseok;Kim, Changhak
    • Korean Journal of Construction Engineering and Management
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    • v.15 no.6
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    • pp.63-70
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    • 2014
  • Deconstruction of the building must be applied firstly in order to improve recycling and reuse of construction wastes. In this study have done a case study for deconstruction of an apartment. All construction waste(CW) which will be generated during deconstruction was examined in each part of the building. Because drawing did not exist in most of the old building, we drew up floor plans of buildings. After analyzing these drawings, estimated quantities of CW. It was measured working time of labor and equipments for deconstruction and general demolition on each building of the apartment. In addition, it was proposed in the volume and weight per unit after analyzing detailed measurement of CW which was generated in the process of deconstruction and traditional demolition. It suggested recovery rate at a site, volume and weight conversion factors, and waste basic unit per area that based on the results of comparative analysis on the amount of CW which is calculated from drawing and generated at a site. These factors will be used fundamental materials for estimating quantities and treatment cost of CW, and scheduling of works.

The Wondong magmatic system : its petrochemical evolution (원동 마그마계 : 암석화학적 진화)

  • 황상구
    • The Journal of the Petrological Society of Korea
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    • v.6 no.3
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    • pp.166-184
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    • 1997
  • The Wondong caldea is a deeply eroded structure that offers spectacular exposures through the core and margins of a resurgent caldera. The Wondong Tuff and the postcollapse intrusions range from medium-silica rhyolite to rhyodacite in composition and the postcollapse lava and tuff, preresurgent and resurgent intrusions also range from medium-silica rhyolite to an-desite, which jump to gap dacite composition. The continuous compositional zonations generally define a large stratified magma system in the postcollapse and resurgent magma chamber. Isotopic and trace element evidence suggest that the compositional zonations might have resulted from the differentiations from crystal fractionations of a parental andesitic magma, accompanying a little contamination from the crustal assimilations near the chamber roof and wall. But chemically and isotopically distinct late intusions might have resulted from emplacement of any different magma batch.

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A Change of Turbidity on Forest Stands by Rainfall Characteristics in Small Watershed (산지소유역에 있어서 강우특성에 따른 임분별 탁도 변화)

  • Ma, Ho-Seop;Kang, Won-Seok;Kang, Eun-Min
    • Journal of Korean Society of Forest Science
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    • v.101 no.3
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    • pp.381-386
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    • 2012
  • This study was carried out to clarify the turbidity change on three stands (Castanea crenata, Pinus densiflora and Plantation Land) by rainfall characteristics in small watershed. The change of turbidity showed in order of plantation land, Castanea stand and Pinus stand. The linear equations models between turbidity and rainfall intensity were able to account for 91% in Castanea stand, 80% in Pinus stand and 71% in plantation land. The linear equations models between turbidity and duration of rainfall were able to account for about 0-1% in three stands. The linear equations models between turbidity and preceding dry days were able to account for about 30% in three stands. The linear equations models between turbidity and accumulative rainfall were able to account for about 6-22% in three stands. The results indicates that soil runoff by land use and development of forest area could be applied to the mitigation measures such as afforestation and erosion check dam for erosion control and water quality management in small watershed.

Lipid Contents and Fatty Acid Composition of Three Lipid Classes in Korean Pinenut (잣지질 성분의 분획정량 및 각 획분의 지방산 조성)

  • Kim, Myung;Rhee, Sook-Hee;Cheigh, Hong-Sik
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.13 no.4
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    • pp.406-412
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    • 1984
  • Total lipids (TL) from Korean pinenut (Pinuskoraiensis S & Z) were extracted, purified and fractionated into three lipid classes (neutral lipid: NL, glycolipid; GL, phospholipid; PL). Lipid contents(constituent components) and fatty acid composition of three lipid classes were determined by thin layer chromatography and gas chromatography. TL ranged from 69.0% to 69.8% in fresh pinenut and consisted of 95.9% to 96.7% NL, 3.2% to2.5% GL and 0.9% to 0.8% PL. In the NL, triglycerides were predominant (80.8%) with the smaller amounts of sterol, diglycerides, free fatty acids, sterol esters and hydrocarbons. Monogalactosyl diglycerides and esterified steryl glycosides (23.5%) were the major components of GL, but cerebrosides, steryl glycosides and digalactosyl diglycerides were also found as minor components. Of the PL, phosphatidyl choline (40.2%) and phosphatidyl ethanolamine (19.4%) were the major components, comprising over 60% of this class. Phosphatidyl inositol, lysophosphatidyl choline were also present in the PL. The major fatty acids in the NL were linoleic acid (48.6%), oleic acid (28.8%) and arachidic acid(14.4%), The fatty acid composition in the GL was similar to the pattern in the NL, but PL contained a higher percentage of palmitic acid (17.7%) and stearic acid (6.0%) than other lipid classes.

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Studies on the Cellulase. (V) -Fractionation of Cellulolytic Complex produced by Trichoderma $viride(O_2-1)$ (섬유소(纖維素) 분해효소(分解酵素)에 관(關)한 연구(硏究) (제5보(第5報)) -Trichoderma $(O_2-1)$가 생성(生成)하는 Cellulolytic Complex의 분별(分別)에 대(對)하여-)

  • Sung, Nack-Kie
    • Applied Biological Chemistry
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    • v.12
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    • pp.99-105
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    • 1969
  • The yield of cellulase derived from Trichoderma $(O_2-1)$ was remarkably varied with various concentration of ethanol and acetone in purification of the enzyme. In the purification with ethanol of ${\beta}-glucosidase$, the best result was obtained in the concentration of 60% and, of CMCase and of filter paper disintegrating enzyme 80%. And in the purification with acetone of ${\beta}-glucosidase$, filter paper disintegrating enzyme, and CMCase, in the concentration of 60%, 80%, and 90% respectively, was shown the best yield. The activities of crude Cellulase preparation could be seperated into few of fractions by column chromatography with Silica gel, Cellulose powder, and gauze. Most of CMCase, avicelase, and ${\beta}-glucosidase$ were eluted, but most of filter paper disintegrating enzyme and the rest of enzymes mentioned the above were absorbed, and were eluted with water. Therefore, it was considered that CMCase is different from filter paper disintegrating enzyme in properties. The relative activity of CMCase was different from that of avicelase in the peak of elusion part. And it was considered that filter paper disintegrating enzyme and cellulose powder saccharifying enzyme was seperated respectively as absorption part and non absorption part. The auther came to the conclusion that at least there were more than three sorts of cellulase in Trichoderma $(O_2-1)$ cellulase preparation.

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