• Title/Summary/Keyword: 변이효과

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Effect of Sequence Variation in Bovine Mitochondrial DNA D-Ioop Region on ~ilk Production for Hanwoo (한우 산유량에 미치는 Mitochondrial DNA D-loop영역의 염기서열 변이효과)

  • Kong, H.S.;Oh, J.D.;Lim, H.J.;Lee, H.K.;Jeon, G.J.;Yoon, D.H.;Jeon, G.J.;Choi, J.G.;Choi, Y.H.;Cho, B.W.
    • Journal of Animal Science and Technology
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    • v.46 no.5
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    • pp.729-734
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    • 2004
  • This study was performed to analyze the sequence variations of mtDNA D-loop and their effects on milk in Hanwoo(Korean cattle). The resulting sequences were compared with previously published sequences for other cattle breeds (GenBank JOI394). The Polymerase Chain Reaction was performed to amplify a total of 964 bp between nucleotide 15758 and 383 within D-loop region of mtDNA using specific primers. Twenty polymorphic sites by nucleotide substitution were found in mtDNA D-loop region of Hanwoo. The frequencies of positions at 8, 169, 16042, 16051, 16057, 16093, 16119, 16122, 16209, 16255 and 16302 nt with high levels of sequence polymorphism were 0.150, 0.950, 0.085, 0.138, 0.106, 0.085, 0.138, 0.212, 0.085, 0.148 and 0.180, respectively. The substitution effect at 16119(p<0.1) and 16185(p< 0.05) nt was found significant on milk production. Polymorphism of mtDNA sequence in D-Ioop region could be useful for the analysis of cytoplasmic genetic variation and associations with the other economically important traits and maternal lineage analysis in Hanwoo.

Non-linear Normalization for Pair-wise Discrimination Based On Local Contribution Measure (유사 문자쌍 구분을 위한 지역적 공헌도 기반 비선형 정규화)

  • Ryu, Sang-Jun;Kim, In-Jung
    • Proceedings of the Korea Information Processing Society Conference
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    • 2010.04a
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    • pp.393-396
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    • 2010
  • 지금까지 필기 변이를 완화하기 위한 다양한 비선형 정규화 방법들이 제안되었으며 실제 인식 시스템에서 상당한 인식률 개선 효과를 나타내었다. 그러나, 필기 한글 인식에 있어서는 필기 변이 외에도 문자간의 높은 유사도로 인해 높은 인식률을 얻는데 어려움을 겪고 있다. 한글과 같이 문자간 유사도가 높은 언어를 효과적으로 인식하기 위해서는 필기 변이를 흡수하는 것뿐 아니라, 유사 문자간의 차이를 정확히 찾아내어 그 차이점을 부각시키는 것이 요구된다. 본 논문에서는 유사 문자간의 차이점을 부각시킬 수 있는 비선형 정규화 방법을 제안한다. 기존의 비선형 정규화 방법들이 영상의 지역적 복잡도를 균일화 함으로써 정규화를 수행했던 것에 반해, 제안하는 방법에서는 유사 문자쌍의 구분에 있어 지역적 공헌도에 기반하여 영상을 정규화한다. 즉, 유사 문자쌍 구분에 공헌도가 높은 지역은 확대하고 그렇지 않은 지역은 축소한다. 그 결과, 문자간에 서로 상이한 지역을 강조 함으로써 유사 문자쌍에 대한 구분력을 높인다. 실험 결과, 제안하는 방법으로 정규화된 영상에서는 유사 문자쌍의 차이점이 확대되었으며, 문자쌍의 구분 성능 또한 향상되었다.

Optimization of Mutant Strain of the Sulfur-Oxidizing Bacteria, Thiobacillus sp. UIW-6 (황산화 세균 Thiobacillus sp. UIW-6 변이주의 성장 최적화)

  • Shin, Seung-Yong;Kang, Sun-Chul
    • Korean Journal of Environmental Agriculture
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    • v.25 no.2
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    • pp.124-128
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    • 2006
  • To reducing offensive odor form compost UIW-6 mutant obtained by UV treatment from sulfur-oxidizing bacteria, Thiobacillus sp. IW. The UIW-6 mutant was found 1.6 times faster in growth than the parent strain on thiosulfate medium (TM) at 36 h after incubation. Initial pH, temperature and agitation for the optimum growth of UIW-6 were 6.5, $35^{\circ}C$ and 200 rpm, respectively. The UIW-6 mutant growth was two times higher than parent strain at 6 h culture in TM liquid medium containing 50 mM sodium thiosulfate. The UIW-6 mutant used fructose and sucrose as carbon sources and yeast extract> tryptone> peptone as nitrogen ones. It was found that the growth of UIW-6 was increased in addition of 0.2% yeast extract.

Antioxidative and Antimutagenic Effects of the Ethanol Elrtract from Cordyceps militaris (번데기동충하초(Cordyceps militaris) 에탄을 추출물의 항산화성 및 항돌연변이원성 효과)

  • 김미남;오상화;이득식;함승시
    • Food Science and Preservation
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    • v.8 no.1
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    • pp.109-117
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    • 2001
  • Cordyceps militaris is a parasitic fungus that has been used as a Chinese medicine for the treatment of fatigue, debility, kidney disease, tuberculosis, asthma and cardiac insufficiency etc. This study was carried out to determine the antioxidative and antimutagenic effects of Cordyceps militaris using DPPH free radical donating method and Ames test, respectively. They were extracted with ethanol and then further fractionated to n-hexane, chloroform, ethyl acetate, butanol and water, stepwise. Among five fractions, the EtOAc and BuOH fractions showed the highest electron donating activities, about 2-fold higher than other fractions. In Ames test, most of the extracts had strong antimutagenic effects against the mutagenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine(MNNG), 4-nitroquinoline-1-oxide(4NQO), benzo($\alpha$)pyrene(B($\alpha$)P) and 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indol (Trp-P-1). The EtOH extracts of C. militaris (200 $\mu\textrm{g}$/plate) showed 62.8%, 74.4% and 67.2% inhibitory effects on the mutagenesis induced by 4NQO, B($\alpha$)P and Trp-P-1, respectively, against TA98 strain, whereas 78.1%, 78.6%, 78.6% and 82.7% inhibition were observed on the mutagenesis induced by MNNG, 4NQO, B($\alpha$)P and Trp-P-1, respectively, against TA100 strain. Especially, the BuOH fraction showed the highest antimutagenic effects against mutation induced by MNNG.

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공간통계분석에서 이상점 수정을 위한 방법비교

  • Lee, Jin-Hui;Sin, Gi-Il
    • Proceedings of the Korean Statistical Society Conference
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    • 2003.05a
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    • pp.275-280
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    • 2003
  • 공간 자료에서 이상점이 존재할 경우 변이도(Variogram)를 추정함에 있어 그 효과를 줄이기 위한 방법으로 로버스트(robust) 변이도를 이용한다. 그러나 이상점이 존재하는 자료분석에서 로버스트 변이도를 사용하기에 앞서 이상점을 수정한 자료를 사용하였을 경우 그 효율성 또한 좋다고 알려져 있다. 본 논문에서는 이상점이 존재하는 자료를 분석함에 있어 기존의 이상점 수정법 및 새로운 이상점 수정법의 효율성을 비교하였다.

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Labor Market Dynamics and Regional Economic Development in Post-Reform China: Implications for Understanding Changing Regional Inequality (경제개혁이후 중국의 노동시장 역동성과 지역경제발전 : 지역격차변화 이해에 대한 함의)

  • 이원호
    • Journal of the Economic Geographical Society of Korea
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    • v.3 no.2
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    • pp.23-42
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    • 2000
  • This study is to investigate spatial patterns of urban labor market growth driven by marketization process and its implication for understanding regional uneven development in post-reform China. Using a shift share analysis, it shows that the geography of employment growth in China's industrial labor market has closely interacted with the space economy of industrial output, which in turn indicates a deepening of economic reform. By decomposing net employment growth into output and productivity effects, it is shown that the non-state sector holds rapid growth of both output and productivity and contributes to net employment growth through positive net shifts. On the contrary, this study also presents that the state sector with relative decrease in output and productivity holds employment decline effects during the reform period. Since there is a significant spatial dimension for the trend above, it is contended that labor market dynamics together with space economy of industrial production play an important role in determining regional patterns of economic development. In addition, through situating this investigation in the context of structural and institutional changes in the reform period, our understanding of regional patterns of labor market growth will be much furthered.

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Biorational Screening System Using Cyanobacteria(Anacystis nidulans $R_2$) for Searching the Photosynthetic Electron Transport Inhibitors (Cyanobacteria를 이용한 광합성 전자전달저해제의 생합리적 스크리닝)

  • Hwang, I.T.;Hong, K.S.;Cho, K.Y.;Yoshida, S.
    • Korean Journal of Weed Science
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    • v.13 no.2
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    • pp.81-88
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    • 1993
  • For searching the photosynthetic electron transport(PET) inhibitors, bio-rational screening system using thylakoid membranes extracted from wild and mutant cyanobacteria(Anacystis nidulans $R_2$) was developed. Generally, thylakoid membrane was more sensitive to the tested herbicides than the chloroplast from spinach in the Hill reaction. Higher resistant characteristics appeared in mutant D-5, Di-22 to diuron and mutant G-264 to atrazine as compared to wild type. To test the reaction of thylakoid membrane to herbicides, diuron and atrazine were applied simultaneously. Diuron and atrazine competed each other for binding with substituted amino acids, while diuron and dinoseb were non-competitive, and inhibiting activity was increased. Conclusively, bio-rational screening system using cyanobacteria was proved to be fast and efficient screening method for the development of PET inhibitors.

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Amino Acid Nutrition on Growth and Reproduction of Potato Dry Rot Fusarium roseum ‘Sambucinum' Variants (감자 건부(乾腐) Fusarium roseum ‘Sambucinum’ 변이체(變異體)의 균사생장(菌絲生長) 및 분생포자(分生胞子) 형성(形成)에 미치는 아미노산(酸) 영양(營養))

  • Lee, Chang-Un
    • The Korean Journal of Mycology
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    • v.10 no.4
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    • pp.187-192
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    • 1982
  • The effects of amino acids on mycerial growth and sporulation of the decreased and increased pathogenicity variants of potato dry rot Fusarium roseum ‘Sambucinum' were as following. The increased pathogenicity variants Ic52 and Ic116 showed the trend of greater mycerial growth, marking up to 67mg on leucine, than the decreased pathogenicity variants Dc14 and Dc91, and produced markedly low conidia below $25{\times}10^{4}/ml$ or no sporulation. On methionine all the variants and the wild type showed the lowest growth recording 14mg to 20mg with no sporulation. Cystine similarly as glysine supported the poor growth 30mg to 19mg of the variants Dc14 and Dc91, respectively, and did not support the sporulation. The former amino acid like asparagine supported the growth of the variants Ic52 and Ic1l6 marking 47mg and 36mg, respectively. On all the eleven amino acids the variant Dc14 showed the trend of more mycerial growth and sporulation than the variant Dc91 which marked the exceptionally high sporulation $195{\times}10^{4}/ml$ on glutamic acid.

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Modeling and Analysis of Soil Moisture Dynamics in the Large River Basin (넓은 유역에 있어서의 토양 수분 동력학의 모델링과 분석)

  • 이재수
    • Proceedings of the Korea Water Resources Association Conference
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    • 1994.02a
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    • pp.449-456
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    • 1994
  • 넓은 지역(Arkansas River Basin)에 대하여 토양 수분을 기본으로한 물 수지 모델이 계절별 년별 시간단위로 연구되었다. 지표면과 대기 수분사이의 상호 작용과 재순환 효과에 대한 연구가 유역의 매개 변수화 과정에서 수행되었으며 대규모의 지표면과 대기사이의 상호 작용에 의하여 넓은 지역의 지표 수문은 장기간의 확률분포함수에 있어서 두가지 즉 건조와 습한 안정상태의 영향을 받는다. 토양수분 균형 방정식에서 추계학적 변동은 주위환경 변동에 의하여 야기되는 안정상태 사이의 변이와 함께 분리된 선호하는 통계학적 안정상태를 초래한다. 과거의 자료를 바탕으로 비선형 물수지 모델이 Arkansas강 유역에 대하여 검정되었다. 모델에서 안정상태 사이의 평균 변이시간이 물리과정의 추계학적 표현과 검정된 모델변수들로부터 계산되었다. 본 연구는 안정상태 사이의 변이시간 혹은 거주시간, 즉 시스템이 주어진 안정상태에 머무는 시간(가뭄이나 홍수상태의 지속기간)의 예측과 밀접한 관계가 있다.

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